Recent Advances in Potential Clinical Application of Ghrelin in Obesity by Christine Delporte

“…Ghrelin is involved in weight regulation, obesity, type 2 diabetes, and metabolic syndrome. Furthermore, a better understanding of ghrelin biology led to the identification of molecular targets modulating ghrelin levels and/or its biological effects: GOAT, ghrelin, and GHS-R1a. …”
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The Mediterranean Lifestyle: The Power of Food by Charissa Lim, Alexa Hosey, Farah Tadros, Madison Woodard, Jeanette Andrade

“…This dietary pattern has been shown to improve heart health, maintain weight, and reduce the risk for chronic diseases such as cardiovascular disease and type 2 diabetes. This new 6-page publication discusses the Mediterranean dietary pattern and provides tips to incorporate this lifestyle into daily life, as well as sample recipes. …”
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Hubungan Berbagai Faktor Risiko Terhadap Kejadian Penyakit Jantung Koroner Pada Penderita Diabetes Melitus Tipe 2 by Fadma Yuliani, Fadil Oenzil, Detty Iryani

“…<br />Kata kunci: DM tipe 2, PJK, faktor risiko</p><p>Abstract<br />The main causes of mortality and morbidity in type 2 diabetes mellitus (DM) patients is coronary heart disease (CHD) which adults who suffer from DM are two to four times have the risk of heart disease than people without DM. …”
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Validation of the Chronic Liver Disease Questionnaire for MASH (CLDQ-MASH) by Zobair M. Younossi, Maria Stepanova, Issah Younossi, Andrei Racila

“…Known-groups validity assessment confirmed that CLDQ-MASH can discriminate patients based on liver disease severity (histology- and NIT-based) and the presence of non-hepatic comorbidities (obesity, type 2 diabetes, depression, clinically overt fatigue, insomnia). …”
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Establishment of a New Hyperglycemic Obesity Cardiac Dysfunction Mouse Model with Triacsin C by ZHAO Xiaona, WANG Peng, YE Maoqing, QU Xinkai

“…Objective This study aims to establish a novel hyperglycemic obesity mouse model by utilizing Triacsin C, an inhibitor of acyl-CoA synthetase long-chain family member 1 (ACSL1), combined with a high-fat diet, to simulate the changes in adipose tissue and cardiac function observed in patients with obesity-related type 2 diabetes.MethodsTwenty adult SPF-grade male C57BL/6J mice were randomly divided into two groups: the Control group (injected intraperitoneally with citric acid-sodium citrate buffer, Con group) and the TC group (injected intraperitoneally with Triacsin C, TC group). …”
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Alström’s Syndrome, Leber’s Hereditary Optic Neuropathy, or Retinitis Pigmentosa? A Case of Misdiagnosis by Palaiologos Alexopoulos, Chrysanthos Symeonidis, Tryfon Rotsos

“…AS affects metabolism, and symptomatology includes type 2 diabetes mellitus (T2DM), obesity, hypogonadism and gynecomastia in males, progressive bilateral sensorineural hearing loss, cardiomyopathy, nonalcoholic fatty liver disease (NAFLD), cirrhosis, and chronic progressive kidney disease. …”
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Use of Platelet Rich Plasma in the Treatment of Diabetic Foot. Case Report by Enrique Ramón Rodríguez Reyes, Alberto Sánchez Garrido, Elsy Labrada González

“…The case of a 60-year-old female patient with a medical history of type 2 diabetes mellitus diagnosed 15 years ago, who suffered a puncture wound in the region of the sole of the foot, is presented. …”
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Evaluation of Therapeutic Benefits of a Novel Herbal Ingredient-Based Hyaluronic Acid Gel as Monotherapy for Inflammatory Enlargement of a Patient with Diabetes Mellitus by Jaahnavi Lanka, Santhosh Kumar

“…A patient aged 64 years with type 2 diabetes mellitus reported to the Department of Periodontology. …”
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Pharma TARP: A Troubled Asset Relief Program for Novel, Abandoned Projects in the Pharmaceutical Industry by Tamas Bartfai, Graham Vaughan Lees

“…Society has a real need for the drugs that are no longer going to be developed for, among others, drug-resistant epilepsy, neuropathic and cancer pain, type-2 diabetes, obesity, and schizophrenia. The authors propose a radical response by the U.S. government and the National Institutes of Health to rescue these abandoned projects, and to continue selected programs for drug approval by the U.S. …”
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Peroxisome Proliferator-Activated Receptor Agonists: Do They Increase Cardiovascular Risk? by Ahmad Aljada, Kshitij Ashwin Shah, Shaker A. Mousa

“…Cardiovascular disease is a major cause of morbidity and mortality among people with type 2 diabetes mellitus. The peroxisome proliferator-activated receptor (PPAR) agonists have a significant role on glucose and fat metabolism. …”
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Renal and Vascular Mechanisms of Thiazolidinedione-Induced Fluid Retention by Tianxin Yang, Sunhapas Soodvilai

“…Thiazolidinediones (TZDs) are peroxisome proliferator-activated receptor subtype γ (PPARγ) activators that are clinically used as an insulin sensitizer for glycemic control in patients with type 2 diabetes. Additionally, TZDs exhibit novel anti-inflammatory, antioxidant, and antiproliferative properties, indicating therapeutic potential for a wide variety of diseases associated with diabetes and other conditions. …”
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Antidiabetic Potential of Phytochemicals Found in Vernonia amygdalina by Archna Talwar, Neha Chakraborty, Manaal Zahera, Shruti Anand, Irshad Ahmad, Samra Siddiqui, Avni Nayyar, Ashanul Haque, Mohd Saeed

“…Type 2 diabetes mellitus (T2DM), or “insulin-independent diabetes mellitus,” is a worldwide health concern. …”
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Does Hsp60 Provide a Link between Mitochondrial Stress and Inflammation in Diabetes Mellitus? by Joshua Juwono, Ryan D. Martinus

“…The focus of this review is to summarise the known relationships between the expression of heat shock protein 60 (Hsp60) and its association with the pathogenesis of Type 1 and Type 2 diabetes mellitus. Hsp60 is a mitochondrial stress protein that is induced by mitochondrial impairment. …”
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Exploring the Interplay of Smoking Behavior, Heart Rate Variability, Pulmonary Function Test Results, Diabetes, and Mood Disorders: A Systematic Review by Bipin Kumar, Tanuj Mathur, Yoshita R. Annepu, Krishna K. Annepu, Perugu D. K. Chaitanya

“…The review found that conditions such as hypertension and type 2 diabetes exacerbate cardiac autonomic dysfunction, thereby aggravating cardiovascular risks. …”
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The Relationship between Serum Ferritin and Insulin Resistance in Different Glucose Metabolism in Nonobese Han Adults by Bo-wei Liu, Xu-min Xuan, Jun-ru Liu, Fang-ning Li, Fu-Zai Yin

“…The exact mechanism through which elevated serum ferritin promotes the development of type 2 diabetes is unknown. This study showed that ferritin concentration in impaired glucose regulation and newly diagnosed diabetes mellitus subjects of nonobesity already significantly increased when compared with normal glucose tolerant subjects of nonobesity. …”
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Comorbidities and Ethnocultural Factors Limit the Physical Activity of Rural Sri Lankan Patients with Diabetes Mellitus by Arjuna Medagama, Manoj Galgomuwa

“…Four hundred patients with type 2 diabetes, comprising 113 (28.2%) males and 287 (71.7%) females, were enrolled. …”
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Enhancing Exercise Responsiveness across Prediabetes Phenotypes by Targeting Insulin Sensitivity with Nutrition by Julian M. Gaitan, Arthur Weltman, Steven K. Malin

“…Herein, we propose the novel hypothesis that the combination of individualized nutrition therapy and exercise should be based on the clinical pathology of prediabetes to overcome exercise resistance and improve responsiveness in people at risk for type 2 diabetes and cardiovascular disease.…”
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The therapeutic agents that target ATP-sensitive potassium channels by Rubaiy Hussein N.

“…ATP-sensitive potassium (KATP) channels are a major drug target for the treatment of type-2 diabetes. KATP channels are ubiquitously expressed and link the metabolic state to electrical excitability. …”
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Endothelial Dysfunction and Oxidative Stress in Patients with Severe Coronary Artery Disease: Does Diabetes Play a Contributing Role? by Alexandra Maria Boieriu, Cezar Dumitrel Luca, Carmen Daniela Neculoiu, Alina Bisoc, Diana Țînț

“…This study evaluated endothelial dysfunction and oxidative stress in patients with severe coronary artery disease (CAD) undergoing coronary artery bypass graft (CABG) surgery, comparing those with and without type 2 diabetes mellitus (T2DM). <i>Materials and Methods:</i> We included 84 patients with severe coronary artery disease (33 of whom had type 2 diabetes mellitus) who underwent clinical assessments, ultrasound, and coronaryangiography. …”
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Traditional and Non-Traditional Risk Factors of Acute Coronary Syndrome in Young Women: Evidence from the ANCORS-YW Study by Ibdah R, Al-Nusair M, Abuhalimeh R, Mahmoud SA, Laswi B, Rawashdeh S, Hamoudeh A, Kheirallah KA

“…The ACS group, compared to control group, had higher proportions of type-2 diabetes (41.6%vs.11.7%, p< 0.001), hypertension (53.9%vs.23.4%, p< 0.001), tobacco use (37.7%vs.24.2%, p=0.001), family history of cardiovascular disease (53.2%vs.23.4%, p< 0.001), metabolic syndrome (14.3%vs.2.4%, p< 0.001), and preterm delivery (24.7%vs.16.7%, p=0.032). …”
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