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1361
Health literacy in context: struggling to self-manage diabetes – a longitudinal qualitative study
Published 2022-06-01“…The purpose of this qualitative study was to provide a detailed analysis of the health literacy of people with type 2 diabetes in relation to their daily self-care practices.Design Nested qualitative study in the ERMIES randomised controlled trial testing a 2-year structured care in type 2 diabetes. …”
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1362
The influence of gender and waist circumference in the association of body fat with cardiometabolic diseases
Published 2025-01-01“…Information on demographic and lifestyle factors, and history of cardiometabolic diseases (metabolic syndrome, type 2 diabetes, non-alcoholic fatty liver disease (NAFLD), and myocardial infarction) was obtained. …”
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1363
Genetic insights into the risk of hip osteoarthritis on stroke: A single-variable and multivariable Mendelian randomization.
Published 2025-01-01“…In Multivariable Mendelian randomization, factors such as cigarettes per day, alcoholic drinks per week, hypertension, body mass index, type 2 diabetes, C-reactive protein, rheumatoid arthritis were incorporated to further account for the independent causal effects of multiple correlated exposures.…”
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1364
Finerenone in the management of diabetes kidney disease
Published 2025-02-01“…Abstract People with type 2 diabetes are at risk of developing progressive diabetic kidney disease (DKD) and end stage kidney failure. …”
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1365
Risk Factors and Consequent Diseases of Atherosclerosis in a Population Treated in a Medical Office
Published 2024-11-01“…Overweight and obesity has the highest risk associated with altered waist circumference; arterial hypertension with type 2 diabetes mellitus; dyslipidemia with family history of dyslipidemia; and type 2 diabetes mellitus with dyslipidemia and with a family history of type 2 diabetes mellitus. …”
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1366
Diabetic Cataract in Spontaneously Diabetic Torii Fatty Rats
Published 2020-01-01“…Spontaneously Diabetic Torii (SDT) fatty rat is a novel animal model of type 2 diabetes with obesity. SDT fatty rats develop hyperglycemia, dyslipidemia, and other diabetic complications including ocular disorders; however, diabetic cataract formation in SDT fatty rats has not been fully investigated. …”
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1367
Testosterone Deficiency, Cardiac Health, and Older Men
Published 2014-01-01“…The prevalence rates of testosterone deficiency vary according to different studies but may be as high as 40% in populations of patients with type 2 diabetes. There is increasing evidence that testosterone deficiency is associated with increased cardiovascular and all-cause mortality. …”
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1368
Sodium-Glucose Transport Protein 2 Inhibitors Association with Euglycemic Diabetic Ketoacidosis
Published 2023-01-01“…Diabetic ketoacidosis (DKA) is a life-threatening medical emergency that occurs in both type 1 and type 2 diabetes mellitus. Here, we describe the case of a 49 year-old male patient with type 2 diabetes mellitus who presented to the emergency department with complaints of epigastric abdominal pain and intractable vomiting. …”
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1369
The Genetics of PTPN1 and Obesity: Insights from Mouse Models of Tissue-Specific PTP1B Deficiency
Published 2012-01-01“…Due to its prominent role in regulating metabolism, PTP1B is a promising therapeutic target for the treatment of human obesity and type 2 diabetes. The PTP1B protein is encoded by the PTPN1 gene on human chromosome 20q13, a region that shows linkage with insulin resistance, type 2 diabetes, and obesity in human populations. …”
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1370
Therapeutic Potential of Retinoid X Receptor Modulators for the Treatment of the Metabolic Syndrome
Published 2007-01-01“…These compounds have glucose-lowering, insulin-sensitizing, and antiobesity effects in animal models of insulin resistance and type 2 diabetes. However, undesirable side effects such as hypertriglyceridemia and suppression of the thyroid hormone axis also occur. …”
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1371
Relationships of Adrenoceptor Polymorphisms with Obesity
Published 2011-01-01“…Obesity, hypertension, and type 2 diabetes are rapidly growing public health problems. …”
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1372
Pengaruh Stretching Exercise Pada Kualitas Hidup Dan Status Fungsional Lansia Penderita Dm Tipe 2
Published 2022-10-01“…The total sample in this study was 30 elderly with type 2 diabetes. The sample was taken using a consecutive sampling technique. …”
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1373
The Association of a Genetic Variant in SCAF8-CNKSR3 with Diabetic Kidney Disease and Diabetic Retinopathy in a Chinese Population
Published 2017-01-01“…We aimed to investigate the association between the variant rs955333 in SCAF8-CNKSR3 and DKD susceptibility in Chinese type 2 diabetes patients. Methods. The variant rs955333 was genotyped in 1884 Chinese type 2 diabetes patients. …”
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1374
PPARγ Agonist Rosiglitazone Suppresses Renal mPGES-1/PGE2 Pathway in db/db Mice
Published 2013-01-01“…Collectively, the present study demonstrated an inhibitory effect of PPARγ activation on renal mPGES-1/PGE2/EP4 pathway in type-2 diabetes and suggested that mPGES-1 may potentially serve as a therapeutic target for treating type-2 diabetes-associated DN.…”
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1375
Skewed Epigenetics: An Alternative Therapeutic Option for Diabetes Complications
Published 2015-01-01“…Vascular complications are major causes of morbidity and mortality in type 2 diabetes patients. Mitochondrial reactive oxygen species (ROS) generation and a lack of efficient antioxidant machinery, a result of hyperglycaemia, mainly contribute to this problem. …”
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1376
Adipokines and Hepatic Insulin Resistance
Published 2013-01-01“…Obesity is a major risk factor for insulin resistance and type 2 diabetes. Adipose tissue is now considered to be an active endocrine organ that secretes various adipokines such as adiponectin, leptin, resistin, tumour necrosis factor-α, and interleukin-6. …”
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1377
Irisin a Novel Metabolic Biomarker: Present Knowledge and Future Directions
Published 2018-01-01“…The rising prevalence of chronic diseases such as type 2 diabetes and cardiovascular diseases owing to fat mass excess has been described. …”
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1378
The Role of Organelle Stresses in Diabetes Mellitus and Obesity: Implication for Treatment
Published 2015-01-01“…The type 2 diabetes pandemic in recent decades is a huge global health threat. …”
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1379
Impaired Muscle Regeneration in Ob/ob and Db/db Mice
Published 2011-01-01“…In obesity and type 2 diabetes, efficient skeletal muscle repair following injury may be required, not only for restoring muscle structure and function, but also for maintaining exercise capacity and insulin sensitivity. …”
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Hypoadiponectinemia: A Link between Visceral Obesity and Metabolic Syndrome
Published 2012-01-01“…Metabolic syndrome (MetS) represents a combination of cardiometabolic risk factors, including visceral obesity, glucose intolerance or type 2 diabetes, elevated triglycerides, reduced HDL cholesterol, and hypertension. …”
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