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USC-Derived Small Extracellular Vesicles-Functionalized Scaffolds Promote Scarless Vaginal Defect Repair via Delivery of Decorin and DUSP3 Proteins
Published 2025-02-01“…This study highlights the potential of sEVs-loaded scaffolds as a promising strategy for scarless vaginal repair following vaginoplasty, offering a novel approach for regenerative medicine with significant translational potential for clinical application. Keywords: small extracellular vesicles, urine-derived stem cells, vaginal defects, scarless repair, anti-fibrosis…”
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5144
Unraveling complexity and leveraging opportunities in uncommon breast cancer subtypes
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5148
The Platelet-Specific Gene Signature in the Immunoglobulin G4-Related Disease Transcriptome
Published 2025-01-01“…During the selection of differentially expressed genes (DEGs), the translationally active but significantly low amount of platelet mRNA was specifically considered. …”
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5149
A User-Centered Design Approach for a Screening App for People With Cognitive Impairment (digiDEM-SCREEN): Development and Usability Study
Published 2025-01-01“…The app’s usability was evaluated using the System Usability Scale (SUS), and verbal feedback by the end users was obtained using the think-aloud method. ResultsThe translation process during test development took linguistic and cultural aspects into account. …”
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Knockdown of PDPN in astrocytes reduces hippocampal inflammation in T2DM mice
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Automated Recipe Generation AI Tool from Food Images using Machine Learning. Approach for Ingredient Extraction and Cooking Instructions
Published 2025“…Additionally, this chapter discusses the design methodologies and tools utilized to translate conceptual requirements into tangible system specifications. …”
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Community Work Participation and Outcomes in Nyagatare District, Rwanda.
Published 2020“…Basing on the results of the study, the researcher recommends that there is need to find the means to translate the good will of the community on voluntary of community work activities and programs to create public recognition of the value and benefits of realised from their services. …”
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5156
Status of Digital Health Technology Adoption in 5 Vietnamese Hospitals: Cross-Sectional Assessment
Published 2025-02-01“…As projects such as the Vietnam ICU Translational Applications Laboratory are seeking to integrate new digital technologies in the Vietnamese critical care settings, it is important to understand the current status of DHT adoption in Vietnamese hospitals. …”
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Poly (ADP-ribose) (PAR) levels in Peripheral Blood Mononuclear Cells (PBMC) during peri-implantation and early pregnancy in buffalo cows
Published 2023-11-01“… Poly(ADP-ribosyl)ation (PAR) is a reversible post-translational protein modification catalyzed by enzyme members of the poly(ADP-ribose) polymerases (PARPs) family. …”
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Evaluation of circulating tumor DNA as a prognostic and predictive biomarker in BRAF V600E mutated colorectal cancer—results from the FIRE‐4.5 study
Published 2025-02-01“…This study was accompanied by a prospective translational project analyzing cell‐free circulating tumor DNA (ctDNA) in plasma to test whether ctDNA analysis may help to guide clinical treatment decision making. …”
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Selection of terminal Piétrain pigs improves vitality and prevalence of congenital defects in crossbred piglets
Published 2025-01-01“…A joint analysis of the datasets showed a moderate to high genetic correlation (rg=0.52 to 0.84) for porcine congenital splay leg syndrome and pre-weaning mortality, indicating the translatability of estimated breeding values for terminal sires to new farms, specifically for these traits. …”
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Sodium Butyrate: A Multifaceted Modulator in Colorectal Cancer Therapy
Published 2025-01-01“…<i>Results:</i> This study provides the first exploration of <i>MCL-1</i> and <i>PCNA</i> modulation by NaB in the context of CRC and HCT-116 cells, offering significant translational insights. All treatments reduced cell viability, confluence, and number in a dose-dependent manner (<i>p</i> < 0.0001). …”
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