Liver Resection Promotes (Regulates) Proinflammatory Cytokines in Patients with Hepatocellular Carcinoma by Farshid Fathi, Behnam Sanei, Mazdak Ganjalikhani Hakemi, Reza F. Saidi, Abbas Rezaei

“…Liver tissues from 15 patients with HCC were collected and the levels of interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α), IL-1α, IL-1 β, IL-10, and transforming growth factor-beta1 (TGF-β1) were assessed using real-time PCR assay at different times before and after LR. …”
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Golgin Subfamily A Member 5 Is Essential for Production of Extracellular Matrix Proteins during TGF-β1-Induced Periodontal Ligament-Fibroblastic Differentiation by Hyun-Jin Kim, Seong-Min Kim, Min-Jeong Choi, Young-Joo Jang

“…Human periodontal ligament stem cells (hPDLSCs) can be differentiated into periodontal ligament- (PDL-) fibroblastic progenitors by treatment with low concentrations of transforming growth factor beta 1 (TGF-β1). Although much is known about the profibrotic effects of TGF-β1, the molecular mechanisms mediating the activation of fibroblasts in periodontal ligament-fibroblastic differentiation are not well known. …”
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The Protective Effect of Naringenin on Airway Remodeling after Mycoplasma Pneumoniae Infection by Inhibiting Autophagy-Mediated Lung Inflammation and Fibrosis by Yan Lin, Dan Tan, Qianna Kan, Zhen Xiao, Zhiyan Jiang

“…The results show proinflammatory cytokines (interleukin- [IL-] 6, IL-1β, and tumor necrosis factor-α), and transforming growth factor beta (TGF-β) expression was significantly increased after MP infection from both clinical and animal experiment. …”
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The Influence of the Preservation Method and Gamma Irradiation Sterilization on TGF-β and bFGF Levels in Freeze-Dried Amnion Membrane (FD-AM) and Amnion Sponge by Heri Suroto, Deny M. Aryawan, Camilla A. Prakoeswa

“…There were significant decreases in amnion sponge compared to the FD-AM, both in transforming growth factor beta (TGF-β) and basic fibroblast growth factor (bFGF) levels and in the preirradiated and 25 kGy postirradiated preparations (p≤0.05). …”
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Cancer-associated fibroblasts and their role in tumor progression by M. S. Ermakov, A. A. Nushtaeva, V. A. Richter, O. A. Koval

“…To date, many molecular and metabolic inducers of the EMT have been discovered including the transforming growth factor-beta (TGF-β), hypoxia, and inflammation. …”
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Role of Serum and Ultrasonometric Markers in the Early Diagnosis of Malignant Transformation of Periductal Liver Fibrosis in Patients with <i>Opisthorchis Felineus</i> Infection by A. Е. Kovshirina, O. S. Fedorova, Yu. V. Kovshirina, V. A. Petrov

“…A comprehensive one-stage comparative study was conducted in a case-control design, using the assessment of biochemical parameters (lactate, alanine aminotransferase, aspartate aminotransferase, gamma-glutamyl transpeptidase, alkaline phosphatase, glucose, direct and indirect bilirubin, high-density lipoproteins and low-density lipoproteins, triglycerides, urea and total protein), immunological parameters (transforming growth factor beta) and tumor markers (CA 19-9, СYFRA 21-1) in blood serum samples obtained from patients with O. felineus infection, with and without periductal fibrosis, O. felineus-infected patients with cholangiocarcinoma and representatives of control groups. …”
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Zebrafish Fins as a Model System for Skeletal Human Studies by Manuel Marí-Beffa, Jesús A. Santamaría, Carmen Murciano, Leonor Santos-Ruiz, José A. Andrades, Enrique Guerado, José Becerra

“…Many other groups have also shown that molecules from the transforming growth factor-beta superfamily (TGFβ), including BMP2, are effective in promoting chondrogenesis and osteogenesis in vivo in higher vertebrates, including humans. …”
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The Maternal Cytokine and Chemokine Profile of Naturally Conceived Gestations Is Mainly Preserved during In Vitro Fertilization and Egg Donation Pregnancies by Alicia Martínez-Varea, Begoña Pellicer, Vicente Serra, David Hervás-Marín, Alicia Martínez-Romero, José Bellver, Alfredo Perales-Marín, Antonio Pellicer

“…The main outcome measures were, firstly, to follow up plasma levels of interleukin (IL) 1beta, IL2, IL4, IL5, IL6, IL8, IL10, IL17, interferon gamma, tumor necrosis factor-alpha (TNFα), transforming growth factor-beta (TGFβ), regulated upon activation normal T-cell expressed and secreted (RANTES), stromal cell-derived factor 1 alpha (SDF1α), and decidual granulocyte-macrophage colony-stimulating factor (GM-CSF) during the three trimesters of pregnancy during the three trimesters of pregnancy; secondly, to evaluate if the cytokine and chemokine pattern of ED pregnant women differs from that of those with autologous oocytes and, thirdly, to assess if women with preeclampsia show different cytokine and chemokine profile throughout pregnancy versus women with uneventful pregnancies. …”
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Modulation of Biomaterial‐Associated Fibrosis by Means of Combined Physicochemical Material Properties by Lisa E. Tromp, Torben A.B. van derBoon, Roderick H.J. deHilster, Ruud Bank, Patrick van Rijn

“…Normal human dermal fibroblasts (NHDFs) are screened for cell density, area, and myofibroblast markers α‐smooth muscle actin (α‐SMA) and Collagen type I (COL1) after 24 h and 7 days of culture, with or without transforming growth factor‐beta (TGF‐β). Results demonstrated that material properties influence fibroblast behavior after 7 days with TGF‐β stimulation, with wettability emerging as the predominant factor, followed by stiffness. …”
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The Effect of Mesenchymal Stem Cell-Derived Exosomes and miR17-5p Inhibitor on Multicellular Liver Fibrosis Microtissues by Farnaz Sani, Mina Soufi Zomorrod, Negar Azarpira, Masoud Soleimani

“…Furthermore, the expression of collagen I (COL I) and α-smooth muscle actin (α-SMA) as critical matrix components, transforming growth factor beta (TGF-β), and miR-17-5p were measured. …”
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Focal adhesion kinase promotes aerobic glycolysis in hepatic stellate cells via the cyclin D1/c-Myc/MCT-1 pathway to induce liver fibrosis by Tao Huang, Ming-Yu Zhou, Gao-Liang Zou, Rui-Han Hu, Lu Han, Qing-Xiu Zhang, Xue-Ke Zhao

“…The migration, proliferation and aerobic glycolysis of LX-2 cells after stimulation and activation by transforming growth factor beta-1 (TGF-β1) or suppression by PF562271 was assessed in vitro. …”
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KLF12 Aggravates Angiotensin II‐Induced Cardiac Remodeling in Male Mice by Transcriptionally Inhibiting SMAD7 by Min Hu, Shi‐Yu Huang, Yi‐Peng Gao, Yu‐Xin Hu, Sha‐Sha Wang, Teng Teng, Xiao‐Feng Zeng, Qi‐Zhu Tang

“…Mechanistically, we discovered that KLF12 directly binds to the promoter of Smad7, leading to the activation of the TGF‐β (transforming growth factor beta)‐Smad3 pathway. Conclusions In conclusion, KLF12 promoted the development of angiotensin II‐induced cardiac remodeling in male mice. …”
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Unraveling TGF-β1’s Role in Mediating Fibrosis and Cell Death in Feline Kidney Cells by Chanyanuch Intachat, Phongsakorn Chuammitri, Benjaporn Sornpet, Prapas Patchanee, Nawin Manachai, Kakanang Piyarungsri

“…Chronic kidney disease (CKD) is prevalent among older cats. The transforming growth factor beta 1 (TGF-β1) pathway is associated with renal fibrosis. …”
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Surface topography modulates initial platelet adhesion to titanium substrata by Cecilia Yan Guo, Raymond Mo, Hugh Kim

“…In addition, the secretion of critical molecules stored in platelet granules (platelet factor 4, PF4; soluble P-selectin, sCD62P; transforming growth factor-beta1, TGF-β1; platelet-derived growth factor-AB, PDGF-AB) was measured by enzyme-linked immunosorbent assay (ELISA) analysis of the supernatants. …”
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Inhibition of Viability, Proliferation, Cytokines Secretion, Surface Antigen Expression, and Adipogenic and Osteogenic Differentiation of Adipose-Derived Stem Cells by Seven-Day Ex... by Jian Wang, Bo Xiang, Jixian Deng, Darren H. Freed, Rakesh C. Arora, Ganghong Tian

“…The SMF slightly downregulated the expression of cytokines including Vascular Endothelial Growth Factor (VEGF), Insulin-like Growth Factor-1 (IGF-1), Transforming Growth Factor Beta 1 (TGF-β1), genetic markers comprising Stem Cell Antigen-1 (Sca1), Octamer-4 (Oct-4), ATP-binding Cassette Subfamily B Member 1 (ABCB1), adipogenic marker genes containing Lipoprotein Lipase (LPL), Peroxisome Proliferator-Activated Receptor Gamma (PPAR-γ), and osteogenic marker genes including Secreted Phosphor-protein 1 (SPP1) and Osterix (OSX). …”
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Involvement of the TGF-β pathway in epithelialmesenchymal transition promoted by the pulmonary microenvironment in Mycoplasma pneumoniae pneumonia by Fan Lu, Wang Huixia, Xu Nuo, Guo Yun, Li Ling

“…Transcriptome sequencing revealed significant upregulation of pathways including transforming growth factor beta (TGF-β), tumor protein 53 (P53), protein kinase Hippo, Ras-proximate-1 or Ras-related protein 1 (Rap1), and members of class O forkhead box proteins (FoxO) in cells exposed to bronchoalveolar lavage fluid (BALF) from MPP patients with atelectasis. …”
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Diacerein Inhibits Myopia Progression through Lowering Inflammation in Retinal Pigment Epithelial Cell by Peng-Tai Tien, Chia-Hung Lin, Chih-Sheng Chen, Ching-Yao Chang, Hsiangyu Ku, Dekang Gan, Yi-Yu Tsai, Jamie Jiin-Yi Chen, Hui-Ju Lin, Lei Wan

“…Furthermore, we determined the level of transforming growth factor-beta- (TGF-) β1, matrix metalloproteinase- (MMP-) 2, type I collagen, interleukin- (IL-) 6, IL-8, and monocyte chemoattractant protein- (MCP-) 1 in the retina. …”
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The Effects of Immunosuppressive Factors on Primary Dendritic Cells from C57BL/6 and CBA Mice by Vasiliy V. Kurilin, Julia N. Khantakova, Valeriy P. Tereschenko, Julia A. Lopatnikova, Irina A. Obleukhova, Sergey V. Sennikov

“…In C57Bl/6 mice, BAY 11-7082 alone had no effect on the expression of DC maturation molecules (CD80, CD86). Transforming growth factor beta (TGF-β), alone and in combination with BAY 11-7082, reduced the expression of these molecules. …”
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Adipose Tissue-Derived Stem Cells Differentiate into Carcinoma-Associated Fibroblast-Like Cells under the Influence of Tumor-Derived Factors by Constantin Jotzu, Eckhard Alt, Gabriel Welte, Jie Li, Bryan T. Hennessy, Eswaran Devarajan, Srinivasalu Krishnappa, Severin Pinilla, Lilly Droll, Yao-Hua Song

“…The conditioned medium from MDAMB231 and MCF7 contains significant amounts of transforming growth factor-beta 1 (TGFβ1) and the differentiation of hASCs towards CAFs is dependent on TGFβ1 signaling via Smad3 in hASCs. …”
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Contradictory Effect of Lymphocyte Therapy and Prednisolone Therapy on CD3+CD8+CD56+ Natural Killer T Population in Women with Recurrent Spontaneous Abortion by Fatemeh Rezayat, Nafiseh Esmaeil, Abbas Rezaei, Roya Sherkat

“…Furthermore, the concentration of interferon-gamma (IFN-γ), transforming growth factor-beta (TGF-β) and interleukin-10 (IL-10) was measured quantitatively using the enzyme-linked immunosorbent assay technique. …”
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