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Expanding and improving analyses of nucleotide recoding RNA-seq experiments with the EZbakR suite.
Published 2025-07-01“…., s4U and s6G dual labeling), and implements an improved hierarchical model to better account for transcript-to-transcript variance in metabolic label incorporation. EZbakR also generalizes dynamical systems modeling of NR-seq data to support analyses of premature mRNA processing and flow between subcellular compartments. …”
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Distinctive features of IncRNA and mRNA between severe and mild patients with influenza a (H1N1) virus pneumonia
Published 2025-04-01“…Objectives: The objectives of the study were to investigate the transcriptional variances in mRNA and lncRNA between severe and mild cases of H1N1 infection to discern potential markers contributing to the severity of the illness. …”
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Luminal epithelial cells integrate variable responses to aging into stereotypical changes that underlie breast cancer susceptibility
Published 2024-11-01“…In addition to age-dependent directional changes in gene expression, we observed increased transcriptional variance with age that contributed to genome-wide loss of lineage fidelity. …”
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