The crosstalk between senescence, tumor, and immunity: molecular mechanism and therapeutic opportunities by Zehua Wang, Chen Chen, Jiaoyu Ai, Yaping Gao, Lei Wang, Shurui Xia, Yongxu Jia, Yanru Qin

“…Understanding how senescence regulates antitumor immunity, along with new therapeutic interventions, is essential for managing tumor cell senescence and remodeling the immune microenvironment.…”
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Arterial Hypertension and Interleukins: Potential Therapeutic Target or Future Diagnostic Marker? by Daniela Maria Tanase, Evelina Maria Gosav, Smaranda Radu, Anca Ouatu, Ciprian Rezus, Manuela Ciocoiu, Claudia Florida Costea, Mariana Floria

“…Further research is needed to evaluate whether drugs targeting hypertensive-linked proinflammatory cytokines, such as monoclonal antibodies, could become a new therapeutic option in treating arterial hypertension.…”
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Research progress on the therapeutic roles and mechanisms of hydrogen-rich water in periodontitis by LIU Fushuang, WEI Xiaoxuan, ZHOU Jianpeng, WANG Jun

“…Therefore, further clinical studies are required to validate the therapeutic significance and optimal therapeutic regimen of HRW in human periodontitis. …”
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Editorial: New insights into intracellular pathways and therapeutic targets in CNS diseases by Lisa Gherardini

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Therapeutic and subsidiarity principles: an approach to the humanizing character of the Bioethics Ecuadorian Society by Rolando Medina Peña, Guido Estuardo Coronel Núñez, Maigre Gallo González, Diana Elisa Palmero Urquiza

“…The principle of totality or therapeutic, and that of sociability and subsidiarity, are the object of reflection in this study, as well as the way in which they are manifested through the Ecuadorian Society of Bioethics, through the analytical and conceptual foundation on the origin and consistency of these. …”
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Failure of Colorectal Anastomosis: Risk Factors, Prevention, Diagnosis, Therapeutic Tactics by M. F. Cherkasov, A. V. Dmitriev, V. S. Groshilin, S. V. Pereskokov, M. A. Kozyrevskiy, A. A. Urupina

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Molecular landscape of lung cancer: insights into therapeutic targets and clinical outcomes by Saloni Mangal, Abhijit Debnath, Rupa Mazumder, Avijit Mazumder, Rajesh Kumar Singh, Jahanvi Sanchitra, S.K. Asif Jan, Pratibha Pandey, Bimlesh Kumar, Anil Kumar Singh

“…Thus, the treatment of the disease urgently requires the discovery of novel therapeutic approaches. This review identifies and discusses key molecular and genetic targets for LC therapy, highlighting recent advancements and potential clinical applications. …”
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Validation of Colchicine Assay Method for Therapeutic Drug Monitoring in Human Plasma by Fadime Canbolat

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Role of intestinal probiotics in the modulation of lipid metabolism: implications for therapeutic treatments by Xiaoran Song, Yanan Liu, Xin Zhang, Peifang Weng, Ruilin Zhang, Zufang Wu

“…Moreover, we discuss the underlying mechanisms of intestinal probiotics regulating lipid metabolism and summarize the therapeutic strategies for abnormal lipids metabolism. …”
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Therapeutic Drug Monitoring of Meropenem in Neonate with Necrotizing Enterocolitis: A Challenge by Steven De Keukeleire, Daniëlle Borrey, Wim Decaluwe, Marijke Reynders

“…We describe the added value of therapeutic drug monitoring by presenting the case of a preterm infant with severe NEC treated with meropenem. …”
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Uterus Conservative Surgery. A Therapeutic Alternative in Postpartum Obstetric Hemorrhage by Yoan Hernández Cabrera, Marioly Ruiz Hernández

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Drug Repositioning for Gynecologic Tumors: A New Therapeutic Strategy for Cancer by Kouji Banno, Miho Iida, Megumi Yanokura, Haruko Irie, Kenta Masuda, Yusuke Kobayashi, Eiichiro Tominaga, Daisuke Aoki

“…The goals of drug repositioning are to find a new pharmacological effect of a drug for which human safety and pharmacokinetics are established and to expand the therapeutic range of the drug to another disease. Such drug discovery can be performed at low cost and in the short term based on the results of previous clinical trials. …”
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Plasma brain-related biomarkers and potential therapeutic targets in pediatric ECMO by Sue J. Hong, Bradley J. De Souza, Kristen K. Penberthy, Lisa Hwang, David E. Procaccini, John N. Kheir, Melania M. Bembea

“…Further research continues to elucidate the role of biomarkers as predictors, prognosticators, and therapeutic targets.…”
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Therapeutic blockade of CCL17 in obesity-exacerbated osteoarthritic pain and disease by Kevin Ming-Chin Lee, Tanya Lupancu, Stacey N. Keenan, Georgina Bing, Adrian A. Achuthan, Mark Biondo, Kim Gia Lieu, Matthew J. Watt, Eugene Maraskovsky, Bronwyn A. Kingwell, John A. Hamilton

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Progenitor Cells for Arterial Repair: Incremental Advancements towards Therapeutic Reality by Trevor Simard, Richard G. Jung, Pouya Motazedian, Pietro Di Santo, F. Daniel Ramirez, Juan J. Russo, Alisha Labinaz, Altayyeb Yousef, Brijesh Anantharam, Ali Pourdjabbar, Benjamin Hibbert

“…Additionally, we discuss the current state of EPCs as therapeutic agents, focusing on endogenous augmentation and transplantation.…”
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The Role of Aggregates of Therapeutic Protein Products in Immunogenicity: An Evaluation by Mathematical Modeling by Liusong Yin, Xiaoying Chen, Abhinav Tiwari, Paolo Vicini, Timothy P. Hickling

“…Therapeutic protein products (TPP) have been widely used to treat a variety of human diseases, including cancer, hemophilia, and autoimmune diseases. …”
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Factors influencing bone loss in anorexia nervosa: assessment and therapeutic options by Isabelle Legroux, Bernard Cortet

“…The essential role of nutrition-related factors—especially leptin and adiponectin—has been reported in recent studies. Therapeutic strategies to mitigate bone involvement in anorexia are still a matter for debate. …”
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Incidental Finding of Left Ventricular False Chamber: Diagnostic and Therapeutic Implications by Antonello Cuccaro, Riccardo Gorla, Domenico Lumia, Mattia Barbiero, Roberto De Ponti

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A Comprehensive Review of the Development and Therapeutic Use of Antivirals in Flavivirus Infection by Aarti Tripathi, Shailendra Chauhan, Renu Khasa

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Autoimmune Hepatitis—Immunologically Triggered Liver Pathogenesis—Diagnostic and Therapeutic Strategies by Elisabeth Sucher, Robert Sucher, Tanja Gradistanac, Gerald Brandacher, Stefan Schneeberger, Thomas Berg

“…Current experimental investigations of T cell-mediated autoimmune pathways and analysis of changes within the intestinal microbiome might advance our knowledge on the pathogenesis of AIH and trigger a spark of hope for novel therapeutic strategies.…”
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