Reactive Oxygen Species, a Potential Therapeutic Target for Vascular Dementia by Amanda Louise White, Grant M. Talkington, Blake Ouvrier, Saifudeen Ismael, Rebecca J. Solch-Ottaiano, Gregory Bix

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Mitochondrial DNA leakage: underlying mechanisms and therapeutic implications in neurological disorders by Guangming Zhang, Huayuan Wei, Anliu Zhao, Xu Yan, Xiaolu Zhang, Jiali Gan, Maojuan Guo, Jie Wang, Fayan Zhang, Yifang Jiang, Xinxing Liu, Zhen Yang, Xijuan Jiang

“…Advancing our understanding of the complex interplay between mtDNA leakage and neuroinflammation is imperative for developing precision therapeutic interventions for neurological disorders.…”
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The mycobiome in human cancer: analytical challenges, molecular mechanisms, and therapeutic implications by Ting Ding, Chang Liu, Zhengyu Li

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Therapeutic development to accelerate malaria control through intentional intervention layering by Lydia Braunack-Mayer, Narimane Nekkab, Josephine Malinga, Sherrie L. Kelly, Evelyn Ansah, Joerg J. Moehrle, Melissa A. Penny

“…Abstract The clinical development of novel vaccines, injectable therapeutics, and oral chemoprevention drugs has the potential to deliver significant advancements in the prevention of Plasmodium falciparum malaria. …”
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N7-methylguanosine modification in cancers: from mechanisms to therapeutic potential by Qihui Wu, Xiaodan Fu, Guoqian Liu, Xiaoyun He, Yimin Li, Chunlin Ou

“…This suggests that they may be novel therapeutic targets for cancer treatment. On the other hand, the aberrant expression of m7G modification-associated molecules is linked to clinicopathological characteristics, including tumour staging, lymph node metastasis, and unfavourable prognoses in patients with cancer, indicating their potential as tumour biomarkers. …”
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Therapeutic Potential of Retinoid X Receptor Modulators for the Treatment of the Metabolic Syndrome by Jane A. Pinaire, Anne Reifel-Miller

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Biochemistry of Bacterial Biofilm: Insights into Antibiotic Resistance Mechanisms and Therapeutic Intervention by Kashish Azeem, Sadaf Fatima, Asghar Ali, Ayesha Ubaid, Fohad Mabood Husain, Mohammad Abid

“…The identification of vulnerabilities in biofilm architecture and the elucidation of key biofilm-specific targets emerge as crucial focal points for the development of targeted therapeutic strategies. In addressing the limitations of traditional antibiotics, this review discusses innovative therapeutic approaches. …”
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BTK inhibitors are a possible emerging therapeutic target for gastric cancer by José Darío Portillo-Miño, Jhon Jairo Calderon, Arnoldo Riquelme

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Advancing the Fight Against Cervical Cancer: The Promise of Therapeutic HPV Vaccines by Qian Zheng, Misi He, Zejia Mao, Yue Huang, Xiuying Li, Ling Long, Mingfang Guo, Dongling Zou

Subjects: “…therapeutic vaccines…”
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Kidney Transplantation: The Challenge of Human Leukocyte Antigen and Its Therapeutic Strategies by Tilahun Alelign, Momina M. Ahmed, Kidist Bobosha, Yewondwossen Tadesse, Rawleigh Howe, Beyene Petros

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Unraveling the Effect of Immunogenicity on the PK/PD, Efficacy, and Safety of Therapeutic Proteins by Alison Smith, Hugh Manoli, Stacey Jaw, Kimberley Frutoz, Alan L. Epstein, Leslie A. Khawli, Frank-Peter Theil

“…Our discussion will emphasize immunogenicity in the context of therapeutic proteins, a well-known class of biologics. …”
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Dual role of pyroptosis in liver diseases: mechanisms, implications, and therapeutic perspectives by Siyuan Yang, Yunyi Zou, Chunhua Zhong, Zuoqiong Zhou, Xiyang Peng, Changfa Tang

“…This review comprehensively summarizes the dual role of pyroptosis in liver diseases and its therapeutic strategies, offering new theoretical foundations and practical guidance for preventing and treating of liver diseases.…”
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Specific and common therapeutic factors in psychodynamic psychotherapy for children and adolescents: an overview by Sabine Sammer-Schreckenthaler, Gloria Lagetto, Human-Friedrich Unterrainer, Human-Friedrich Unterrainer, Human-Friedrich Unterrainer, Human-Friedrich Unterrainer, Omar C. G. Gelo, Omar C. G. Gelo

“…However, very little is still known about the therapeutic factors responsible for this effectiveness. …”
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Experimental and Clinical Use of Therapeutic Hypothermia for Ischemic Stroke: Opportunities and Limitations by Tine Zgavc, An-Gaëlle Ceulemans, Sophie Sarre, Yvette Michotte, Said Hachimi-Idrissi

“…An emerging treatment, therapeutic hypothermia (TH), is a promising neuroprotective therapy in stroke management. …”
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Galectin-1 as an Emerging Mediator of Cardiovascular Inflammation: Mechanisms and Therapeutic Opportunities by Ignacio M. Seropian, Germán E. González, Sebastián M. Maller, Daniel H. Berrocal, Antonio Abbate, Gabriel A. Rabinovich

“…Here, we discuss the emerging roles of Gal-1 in cardiovascular diseases including acute myocardial infarction, heart failure, Chagas cardiomyopathy, pulmonary hypertension, and ischemic stroke, highlighting underlying anti-inflammatory mechanisms and therapeutic opportunities. Whereas Gal-1 administration emerges as a potential novel treatment option in acute myocardial infarction and ischemic stroke, Gal-1 blockade may contribute to attenuate pulmonary arterial hypertension.…”
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Case report: Therapeutic use of bortezomib in a patient with Schnitzler syndrome by Hua Bai, Dongming Zhou, Jinwen Liu, Jie He, Zhou Min, Wenyong Fan, Bing Chen, Yong Xu

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Role of 3-mercaptopyruvate sulfurtransferase in cancer: Molecular mechanisms and therapeutic perspectives by Ka Zhang, Yi-Wen Zhu, Ao-Qi Tang, Ze-Tao Zhou, Yi-Lun Yang, Zi-Hui Liu, Yan Li, Xiao-Yi Liang, Zhi-Fen Feng, Jun Wang, Tong Jiang, Qi-Ying Jiang, Dong-Dong Wu

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Stimulators and Activators of Soluble Guanylate Cyclase: Review and Potential Therapeutic Indications by Bobby Nossaman, Edward Pankey, Philip Kadowitz

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Therapeutic Potential of α-Synuclein Evolvability for Autosomal Recessive Parkinson’s Disease by Jianshe Wei, Gilbert Ho, Yoshiki Takamatsu, Eliezer Masliah, Makoto Hashimoto

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Extracellular NM23 Protein as a Therapeutic Target for Hematologic Malignancies by Junko Okabe-Kado, Takashi Kasukabe, Yasuhiko Kaneko

“…These results suggest an important role of extracellular NM23-H1 in the malignant progression of leukemia and a potential therapeutic target for these malignancies.…”
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