Therapeutic Effect of Oral Bisphosphonates on Choroidal Neovascularization in the Human Eye by Shigeru Honda, Takayuki Nagai, Naoshi Kondo, Masahide Fukuda, Sentaro Kusuhara, Yasutomo Tsukahara, Akira Negi

“…The purpose of this study is to investigate the therapeutic effects of oral bisphosphonates for CNV in humans. …”
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Gastric antral vascular ectasia. Clinical presentation and therapeutic management by Nélcido Luis Sánchez García, Ulises Periles Gordillo, Frank Pérez Triana, Yoandy Hernández Casas, Alfredo Hierro González

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Depression after Delivery: Risk Factors, Diagnostic and Therapeutic Considerations by Debra A. Scrandis, Tehmina M. Sheikh, Robina Niazi, Leonardo H. Tonelli, Teodor T. Postolache

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Diabetic Cardiomyopathy: Current Approach and Potential Diagnostic and Therapeutic Targets by Georgiana-Emmanuela Gilca, Gabriela Stefanescu, Oana Badulescu, Daniela-Maria Tanase, Iris Bararu, Manuela Ciocoiu

“…Moreover, since a strategy for prevention and treatment in order to improve the prognosis of DCM has not been established, it is important to identify clear pathophysiological landmarks, to pinpoint the available diagnostic possibilities and to spot potential therapeutic targets.…”
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Telitromicine. A new therapeutic option from macrolides to ketolides. by Pedro Miguel Milián Vázquez., Maira Quirós Enríquez., Arlette Linares Borges.

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Ligament-Derived Stem Cells: Identification, Characterisation, and Therapeutic Application by Katie Joanna Lee, Peter David Clegg, Eithne Josephine Comerford, Elizabeth Gail Canty-Laird

“…The role of the LDSC niche on LDSC viability and function will be discussed as well as the therapeutic potential of LDSC niche modulation.…”
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Submassive Pulmonary Thromboembolism in a Patient with Thrombocytopenia: Therapeutic Challenge by Ronni Andrea Muñoz Tovar, Luis Carlos Alvarez Perdomo, Sandra Milena Rojas Molina, Silvana Jimenez Salazar

“…The case establishes a therapeutic challenge for the treating group, leading us to carry out an extensive search of the literature and propose a management algorithm in this complex situation.…”
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Therapeutic Targeting of Fibroblast Growth Factor Receptors in Gastric Cancer by Mikito Inokuchi, Yoshitaka Fujimori, Sho Otsuki, Yuya Sato, Masatoshi Nakagawa, Kazuyuki Kojima

“…This review discusses the clinical relevance of FGFR in GC and examines FGFR as a potential therapeutic target in patients with GC. Preclinical studies in animal models suggest that multitargeted tyrosine kinase inhibitors (TKIs), including FGFR inhibitor, suppress tumor cell proliferation and delay tumor progression. …”
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Multiple Pigmented Bowen’s Disease: A Diagnostic and Therapeutic Dilemma by Pratik Gahalaut, Madhur Kant Rastogi, Nitin Mishra, Sandhya Chauhan

“…This paper is an attempt to review the available literature regarding the pigmented variant of multiple BD. Rationale for a therapeutic trial of UVB therapy for multiple arsenic induced BD is also discussed.…”
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A20 as a Potential Therapeutic Target for COVID‐19 by Yongyao Wu, Lilan He, Rong Li, Jiuxuan Li, Qing Zhao, Bin Shao

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The role of nurses in Operating Therapeutic Groups in the Family Health Strategy by Francielle Rosso Mazzuchello, Luciane B. Ceretta, Magada Tessman Schwalm, Valdemira Santina Dagostim, Maria Tereza Soratto

“…The research aimed to meet the nurses ‘ performance in Operating Therapeutic Groups in the family health strategy of a municipality in the southern region of Santa Catarina. …”
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Pathogenetic Substantiation of the Therapeutic Impact on Microbiota in Irritable Bowel Syndrome by Yu. O. Shulpekova, G. H. Babaeva, V. Yu. Rusyaev

“…This review aims to describe the nature of changes in the intestinal microbiota in irritable bowel syndrome (IBS) and provide a pathogenetic justification of the feasibility of a therapeutic impact on microbiota. General findings. …”
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Phytochemical-based therapeutics from traditional eastern medicine: analgesic effects and ion channel modulation by Sung Eun Kim, Geehoon Chung, Sun Kwang Kim

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Innovative nanoparticle-based approaches for modulating neutrophil extracellular traps in diseases: from mechanisms to therapeutics by Haisong Li, Can Li, Cong Fu, Yizhuo Wang, Tingting Liang, Haitao Wu, Chenxi Wu, Chang Wang, Tianmeng Sun, Shuhan Liu

“…This review explores the biological mechanisms of NET formation, their interactions with NPs, and the therapeutic applications of NP-based drug delivery systems for modulating NETs. …”
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Implications of intratumoral microbiota in tumor metastasis: a special perspective of microorganisms in tumorigenesis and clinical therapeutics by Lei Zhang, Xichu Duan, Yanhua Zhao, Dejiu Zhang, Yuan Zhang

“…Tumor metastasis is the main cause of therapeutic failure and mortality in cancer patients. …”
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The burden of Alagille syndrome: uncovering the potential of emerging therapeutics – a comprehensive systematic literature review by Philip Bufler, Robin Howard, Lucia Quadrado, Guy Lacey, Jolan Terner-Rosenthal, Andrea Goldstein, Pamela Vig, Deirdre Kelly

Evolution of Alzheimer’s Disease Therapeutics: From Conventional Drugs to Medicinal Plants, Immunotherapy, Microbiotherapy and Nanotherapy by Emma Ortiz-Islas, Pedro Montes, Citlali Ekaterina Rodríguez-Pérez, Elizabeth Ruiz-Sánchez, Talía Sánchez-Barbosa, Diego Pichardo-Rojas, Cecilia Zavala-Tecuapetla, Karla Carvajal-Aguilera, Victoria Campos-Peña

“…Among the therapeutic alternatives, immunotherapy stands out, employing monoclonal antibodies to specifically target and eliminate toxic proteins implicated in AD. …”
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Advancing CNS Therapeutics: Enhancing Neurological Disorders with Nanoparticle-Based Gene and Enzyme Replacement Therapies by Liu S, Li H, Xi S, Zhang Y, Sun T

“…A major obstacle in treating these conditions is the blood-brain barrier (BBB), which restricts the passage of therapeutic agents to the brain. Nanotechnology, particularly the use of nanoparticles (NPs), offers a promising solution to this challenge. …”
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The emergence of cell-based protein arrays to test for polyspecific off-target binding of antibody therapeutics by Diana M. Norden, Carmen T. Navia, Jonathan T. Sullivan, Benjamin J. Doranz

“…Moreover, about 20% of therapeutic mAbs in clinical development and currently on the market display off-target binding. …”
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Structure-guided identification of mitogen-activated protein kinase-1 inhibitors towards anticancer therapeutics. by Md Nayab Sulaimani, Shazia Ahmed, Farah Anjum, Taj Mohammad, Anas Shamsi, Ravins Dohare, Md Imtaiyaz Hassan

“…The study highlights that these compounds could be explored further in preclinical and clinical investigations to develop anticancer therapeutics.…”
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