-
1
Rheological monitoring of tau protein polymerisation with acoustic waves sensor
Published 2017-03-01Subjects: Get full text
Article -
2
Association between Elevated Serum Tau Protein Level and Sepsis-Associated Encephalopathy in Patients with Severe Sepsis
Published 2019-01-01“…The aim of this study was to evaluate the potential of using the serum tau protein level in the diagnosis of SAE and the prediction of SAE outcomes. …”
Get full text
Article -
3
-
4
-
5
In search of Alzheimer’s disease treatment methods: trends of clinical trials
Published 2018-03-01Subjects: Get full text
Article -
6
A case report of fatal familial insomnia with cerebrospinal fluid leukocytosis during the COVID-19 epidemic and review of the literature
Published 2024-12-01Subjects: Get full text
Article -
7
Natural bioactive compounds form herbal medicine in Alzheimer’s disease: from the perspective of GSK-3β
Published 2025-02-01Subjects: Get full text
Article -
8
Comparative the efficacy and safety of Gosuranemab, Semorinemab, Tilavonemab, and Zagotenemab in patients with Alzheimer’s disease: a systematic review and network meta-analysis of...
Published 2025-01-01Subjects: “…anti-tau protein monoclonal antibodies…”
Get full text
Article -
9
Application of Low Intensity Ultrasound in the Treatment of Alzheimer’s Disease
Published 2025-03-01“…According to the current known pathological studies, AD biomarker TAU protein, phosphorylated tau and amyloid-β (Aβ) play an important role in the pathophysiological changes of AD. …”
Get full text
Article -
10
Alzheimer's disease and gut-brain axis: Drosophila melanogaster as a model
Published 2025-02-01“…This mini-review explores the relationship between tau protein accumulation and gut dysbiosis in Drosophila melanogaster. …”
Get full text
Article -
11
Proton Pump Inhibitors and Dementia: Physiopathological Mechanisms and Clinical Consequences
Published 2018-01-01“…Although neurological side effects secondary to PPIs are rare, several preclinical reports indicate that PPIs might increase Aβ levels, interact with tau protein, and affect the neuronal microenvironment through several mechanisms. …”
Get full text
Article -
12
Amyloid-β and heart failure in Alzheimer’s disease: the new vistas
Published 2025-02-01“…AD neuropathology is due to the progressive deposition of extracellular amyloid-beta (Aβ) peptide and intracellular hyperphosphorylated tau protein. The accumulated Aβ forms amyloid plaques, while the hyperphosphorylated tau protein forms neurofibrillary tangles (NFTs). …”
Get full text
Article -
13
Generation and characterization of two induced pluripotent stem cell lines (ICGi052-A and ICGi052-B) from a patient with frontotemporal dementia with parkinsonism-17 associated wit...
Published 2024-11-01“…Frontotemporal dementia with parkinsonism-17 is a neurodegenerative disease characterised by pathological aggregation of the tau protein with the formation of neurofibrillary tangles and subsequent neuronal death. …”
Get full text
Article -
14
Tau-Reactive Endogenous Antibodies: Origin, Functionality, and Implications for the Pathophysiology of Alzheimer’s Disease
Published 2019-01-01“…Antibodies against tau protein have been documented both in the brain circulatory system and at the periphery, but their origin and role under normal conditions and in AD remain unclear. …”
Get full text
Article -
15
Diagnosing Sporadic Creutzfeldt-Jakob Disease in a Patient with a Suspected Status Epilepticus in the Intensive Care Unit
Published 2013-01-01“…Clinical signs combined with MRI, EEG, and 14-3-3 and/or tau protein determination might be sufficient to diagnose or exclude sCJD and may therefore prevent the application of unnecessary diagnostic tests.…”
Get full text
Article -
16
Interplay of p23 with FKBP51 and their chaperone complex in regulating tau aggregation
Published 2025-01-01“…Taken together, our findings reveal a co-chaperone mediated Hsp90-independent chaperoning of tau protein.…”
Get full text
Article -
17
Therapeutic Actions of the Thiazolidinediones in Alzheimer’s Disease
Published 2015-01-01“…In the AD brain is common to observe the accumulation of senile plaques formed by amyloid-beta (Aβ) peptide and the neurofibrillary tangles composed of modified tau protein, which both lead to cellular damage and progressive neurodegeneration. …”
Get full text
Article -
18
Navigating the Role and Approach of Gut Microbiota in Addressing Alzheimer's Disease Pathogenesis
Published 2024-11-01“… Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by amyloid beta plaques and tau protein neurofibrillary tangles, leading to cognitive decline. …”
Get full text
Article -
19
Aging-associated sensory decline and Alzheimer’s disease
Published 2024-12-01“…Focusing on molecular mechanisms, the review explores the roles of amyloid-β (Aβ) accumulation and tau protein pathology in sensory decline and their bidirectional relationship with AD. …”
Get full text
Article -
20
Circuitry and Synaptic Dysfunction in Alzheimer’s Disease: A New Tau Hypothesis
Published 2020-01-01“…Confronting this leading hypothesis, a few years ago, we reported that the increase in phosphorylation levels of dendritic Tau, at its microtubule domain (MD), acts as a neuroprotective mechanism that prevents N-methyl-D-aspartate receptor (NMDAr) overexcitation, which allowed us to propose that Tau protein phosphorylated near MD sites is involved in neuroprotection, rather than in neurodegeneration. …”
Get full text
Article