Proteogenomic annotation of T6SS components identified in Bacteroides fragilis secretome by Natalya B. Zakharzhevskaya, Olga Yu Shagaleeva, Daria A. Kashatnikova, Daria A. Kashatnikova, Anton O. Goncharov, Anton O. Goncharov, Daria V. Evsyutina, Dmitry A. Kardonsky, Elizaveta A. Vorobeva, Artemiy S. Silantiev, Viktoria D. Kazakova, Irina V. Kolesnikova, Ivan O. Butenko, Anna A. Vanyushkina, Svetlana V. Smirnova, Andrei V. Chaplin, Andrei V. Chaplin, Boris A. Efimov, Boris A. Efimov

Get full text

A design principle for neuronal firing with up-down oscillation through Na+ dynamics by Tomohide R. Sato, Koji L. Ode, Fukuaki L. Kinoshita, Hiroki R. Ueda

Get full text

Cultural Science Meets Cultural Data Analytics by Ibrus Indrek, Schich Maximilian, Tamm Marek

“…We instead argue for a study of meaning-making practices in human society, but without confining ourselves to traditional humanities scholarship, but rather, learning from new developments in systems biology, evolutionary economics, complexity science and many more. …”
Get full text

Multi-target and natural product-based multi-drug approach for anti-VEGF resistance in glioblastoma by Sasikumar Jalajakumari Soumya, Kesavan Rathi Arya, Chandran Sheela Abhinand, Padmanabhan Sunitha, Ajitha Prabhakaran Athira, Achuthsankar Sukumaran Nair, Oommen V. Oommen, Perumana R. Sudhakaran

Get full text

Understanding integrative approach of translational bioinformatics on cardiovascular disease: Myocardial Ischemia by Yeswanth Ranganathan, Saayaa Nazar, Ravi Shankar Krishnan, Yuvaraj Dinakarkumar, Vijayalakshmi Varadarajan, Lenita Sebastian, Brindha Rethinam

“…Additionally, it examines the application of systems biology and network analysis to understand biological networks, and the use of clinical decision support systems to enhance patient care. …”
Get full text

Digital twins as global learning health and disease models for preventive and personalized medicine by Xinxiu Li, Joseph Loscalzo, A. K. M. Firoj Mahmud, Dina Mansour Aly, Andrey Rzhetsky, Marinka Zitnik, Mikael Benson

Get full text

A ribosome-associating chaperone mediates GTP-driven vectorial folding of nascent eEF1A by Ibrahim M. Sabbarini, Dvir Reif, Kibum Park, Alexander J. McQuown, Anjali R. Nelliat, Charlotte Trejtnar, Volker Dötsch, Eugene I. Shakhnovich, Andrew W. Murray, Vladimir Denic

Get full text

Liver transcriptome analysis reveals PSC-attributed gene set associated with fibrosis progression by Alena Laschtowitz, Eric L. Lindberg, Anna-Maria Liebhoff, Laura Anne Liebig, Christian Casar, Silja Steinmann, Adrien Guillot, Jun Xu, Dorothee Schwinge, Michael Trauner, Ansgar Wilhelm Lohse, Stefan Bonn, Norbert Hübner, Christoph Schramm

Get full text

Targeting protein kinase C-α prolongs survival and restores liver function in sepsis: Evidence from preclinical models by Ling Xiong, Dustin Beyer, Na Liu, Tina Lehmann, Sophie Neugebauer, Sascha Schaeuble, Oliver Sommerfeld, Philipp Ernst, Carl-Magnus Svensson, Sandor Nietzsche, Sebastian Scholl, Tony Bruns, Nikolaus Gaßler, Markus H. Gräler, Marc Thilo Figge, Gianni Panagiotou, Michael Bauer, Adrian T. Press

Get full text

Metabolic deficiencies underlie reduced plasmacytoid dendritic cell IFN-I production following viral infection by Trever T. Greene, Yeara Jo, Carolina Chiale, Monica Macal, Ziyan Fang, Fawziyah S. Khatri, Alicia L. Codrington, Katelynn R. Kazane, Elizabeth Akbulut, Shobha Swaminathan, Yu Fujita, Patricia Fitzgerald-Bocarsly, Thekla Cordes, Christian Metallo, David A. Scott, Elina I. Zúñiga

Get full text

Single-cell transcriptomes of dissecting the intra-tumoral heterogeneity of breast cancer microenvironment by Peixian Chen, Kaifeng Liang, Xiaofan Mao, Qiuyuan Wu, Zhiyan Chen, Yabin Jin, Kairong Lin, Tiancheng He, Shuqing Yang, Huiqi Huang, Guolin Ye, Juntao Gao, Dan Zhou, Zhihao Zeng

Get full text

Oversized cells activate global proteasome-mediated protein degradation to maintain cell size homeostasis by Shixuan Liu, Ceryl Tan, Chloe Melo-Gavin, Miriam B Ginzberg, Ron Blutrich, Nish Patel, Michael Rape, Kevin G Mark, Ran Kafri

Get full text

Benchmarking the identification of a single degraded protein to explore optimal search strategies for ancient proteins by Rodriguez Palomo, Ismael, Nair, Bharath, Chiang, Yun, Dekker, Joannes, Dartigues, Benjamin, Mackie, Meaghan, Evans, Miranda, Macleod, Ruairidh, Olsen, Jesper V., Collins, Matthew J.

Get full text

Whole genome sequencing in early onset advanced heart failure by Erik Linnér, Tomasz Czuba, Olof Gidlöf, Jakob Lundgren, Entela Bollano, Maria Hellberg, Selvi Celik, Neha Pimpalwar, Philipp Rentzsch, Molly Martorella, Anders Gummesson, Olle Melander, Sebastian Albinsson, Göran Dellgren, Jan Borén, Anders Jeppsson, R. Thomas Lumbers, Sonia Shah, Johan Nilsson, Pradeep Natarajan, Tuuli Lappalainen, Malin Levin, Hans Ehrencrona, J. Gustav Smith

Get full text

Evaluation of the ABC pathway in patients with atrial fibrillation: A machine learning cluster analysis by Jingyang Wang, Haiyang Bian, Jiangshan Tan, Jun Zhu, Lulu Wang, Wei Xu, Lei Wei, Xuegong Zhang, Yanmin Yang

Get full text

The ArcB kinase sensor participates in the phagocyte-mediated stress response in Salmonella Typhimurium by Coral Pardo-Esté, Coral Pardo-Esté, Francisca Urbina, Nicolas Aviles, Nicolas Pacheco, Alan Briones, Carolina Cabezas, Vicente Rojas, Valentina Pavez, Yoelvis Sulbaran-Bracho, Yoelvis Sulbaran-Bracho, Alejandro A. Hidalgo, Juan Castro-Severyn, Juan Castro-Severyn, Claudia P. Saavedra

Get full text