Comprehensive analysis of mRNA and miRNA differential expression profiles in the hypothalamus-pituitary-gonadal axis in laying and broodiness period of Wanxi white geese by Xinwei Tong, Xiaojin Li, Yuhua Wang, Fei Xie, Ruidong Li, Man Ren, Qianqian Hu, Shenghe Li

“…In this study, we systematically elucidated the mechanisms by which the HPG axis regulates the broodiness behavior and laying performance of WWG at the post-transcriptional level. …”
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Unveiling the ultimate advantage: a meta-analysis of 3D visualization and problem-based learning in orthopedic education by Ting Li, Yidan Hu, Ruohong Song, Hangyu Liu, Xin Gao, Fei Wang, Chengwei Xiao, Xilin Liu

“…However, there is a conspicuous lack of systematic reviews that thoroughly evaluate both the advantages and drawbacks of integrating 3D with problem-based learning (3D + PBL). …”
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A Test-Retest Study of Single- and Multi-Delay pCASL for Choroid Plexus Perfusion Imaging in Healthy Subjects Aged 19 to 87 Years by Zixuan Liu, Qinyang Shou, Kay Jann, Chenyang Zhao, Danny JJ Wang, Xingfeng Shao

“…However, comprehensive studies comparing the accuracy and reliability of single- and multi-PLD (post-labeling delay) arterial spin labeling (ASL) techniques, specifically in relation to the ChP, remain limited. This study systematically evaluated the test-retest reliability and quantification accuracy of cerebral blood flow (CBF) measurements, focusing on the ChP, using single-delay and multi-delay 3D gradient-and-spin echo (GRASE) pseudo-continuous ASL (pCASL) on 28 subjects (aged 19 to 87 years, 14 males/14 females) at 3.0 tesla. …”
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Distribution and species composition of potato viruses in the Novosibirsk region by V. S. Maslennikova, M. B. Pykhtina, K. A. Tabanyukhov, E. V. Shelikhova, K. I. Mosalev, A. V. Katokhin, A. A. Bondar, A. B. Beklemishev, M. I. Voevoda

“…In this regard, an important condition for preserving the potato seed fund in Russia is systematic monitoring and early highly specific detection of potato viral infections. …”
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Recent trends in research on the role of cholesterol in leukemia: a bibliometric and visualization study by Huijuan Lv, Ke Lu, Ximing Wang, Yanfang Zhang, Mengqi Zhuang, Jing Li, Keli Su, Wen Gao

“…This study employs bibliometric analysis and visualization techniques to investigate research trends regarding cholesterol in leukemia and identify key hotspots.MethodsA systematic search of the Web of Science Core Collection was performed for literature published from 1980 to 2024 using the keywords “cholesterol” and “leukemia,” yielding 1,220 articles. …”
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Partially Isolated Dual Work Function Gate IGZO TFT With Obviously Reduced Leakage Current for 3D DRAMs by Yunjiao Bao, Gangping Yan, Lei Cao, Chuqiao Niu, Qingkun Li, Guanqiao Sang, Lianlian Li, Yanzhao Wei, Xuexiang Zhang, Jie Luo, Yanyu Yang, Gaobo Xu, Huaxiang Yin

“…Furthermore, the impacts of the dual gate work function level, the length, and the type of isolation dielectric between dual work function gates are systematically investigated. The results show that the off-state leakage is further reduced by increasing the difference of the work function levels between in dual gates, the dielectric length (LD) and using the isolation layer with a lower dielectric constant. …”
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The DnaJ-Hsp70-Hsp90 co-chaperon networks in scallops under toxic Alexandrium dinoflagellates exposure by Moli Li, Jie Cheng, Huizhen Wang, Jiaoxia Shi, Xiaogang Xun, Wei Lu, Xubo Wang, Jingjie Hu, Zhenmin Bao, Xiaoli Hu

“…Here, 37 CfDnaJ and 35 PyDnaJ genes were systematically characterized in Zhikong scallop (Chlamys farreri) and Yesso scallop (Patinopecten yessoensis), the important aquaculture bivalve species in China. …”
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Post‐operative incidence of lymphedema after RARP with or without extended pelvic lymph node dissection in a cohort study by Andries Clinckaert, Laura Ysenbaardt, Annabel Bijnens, Charlotte Van Calster, Inge Geraerts, Steven Joniau, Nele Devoogdt, Luc Bijnens, Wouter Everaerts

“…The incidence of lymphedema after ePLND has not been systematically reported in the literature. This study aimed to determine the incidence of lymphedema, describe its clinical characteristics and identify specific risk factors in patients undergoing RARP with or without ePLND. …”
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Understanding the educational inequalities in suicide attempts and their mediators: a Mendelian randomisation study by Jing Wang, Ye Yang, Rui Gao, Lilu Ding, Jiahao Zhu, Dan Zhou, Yingjun Li, Houpu Liu

“…Elucidating modifiable risk factors that serve as intermediaries in the impact of low educational attainment on suicide has the potential to reduce health disparities.Aims To examine the risk factors that mediate the relationship between educational attainment and suicide attempts and quantify their contributions to the mediation effect.Methods We conducted a two-sample Mendelian randomisation (MR) analysis to estimate the causal effect of educational attainment on suicide attempts, utilising genome-wide association study summary statistics from the Integrative Psychiatric Research (iPSYCH; 6024 cases and 44 240 controls) and FinnGen (8978 cases and 368 299 controls). We systematically evaluated 42 putative mediators within the causal pathway connecting reduced educational attainment to suicide attempts and employed two-step and multivariable MR to quantify the proportion of the mediated effect.Results In the combined analysis of iPSYCH and FinnGen, each standard deviation (SD) decrease in genetically predicted educational attainment (equating to 3.4 years of education) was associated with a 105% higher risk of suicide attempts (odds ratio (OR): 2.05; 95% confidence interval (CI): 1.81 to 2.31). …”
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Construction of Quality Index System and Screening of Characteristic Index of Rice for Different Uses by Cuiling ZHU, Shengyang JI, Yanjun LIU, Huaxin SONG, Yafang SHAO, Baiyi LU

“…Taking rice as the object of study, this study systematized quality evaluation indicators, assessment methods, and their foundations, constructing a rice quality indicator system tailored to different uses. …”
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The Beneficial Application of Turmeric (Curcuma longa L.) on Health and Egg Production, in Layers: A Review by Saade Abdalkareem Jasim, Aiman Mohammed Baqir Al‐Dhalimy, Maryam Zokaei, Shadi Salimi, Mohammed Jawad Alnajar, Abhinav Kumar, Enas R. Alwaily, Ahmed Hussein Zwamel, Soura Alaa Hussein, Majid Gholami‐Ahangaran

“…Objective The objective of this review is to assess the current scientific literature on the effects of turmeric supplementation in layer diets and evaluate its impact on layer health and egg production. Methods A systematic search was conducted in Google Scholar database to identify relevant studies published in peer‐reviewed journals. …”
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AnaDetect: An extensive dataset for advancing anemia detection, diagnostic methods, and predictive analytics in healthcareMendeley Data by Mayen Uddin Mojumdar, Dhiman Sarker, Md Assaduzzaman, Md. Anisul Haque Sajeeb, Md. Mohaimenur Rahman, Md Shadikul Bari, Shah Md Tanvir Siddiquee, Narayan Ranjan Chakraborty

“…This dataset captures various hematological parameters of patients suffering from anemia, including sex, age, Hemoglobin level (Hb), oxygen transportation (RBC), packed cell volume (PCV), mean corpuscular volume (MCV), Mean Corpuscular Hemoglobin (MCH), Mean corpuscular hemoglobin concentration (MCHC). The data is systematically collected from patients admitted to Aalok Healthcare Ltd., situated in Dhaka, Bangladesh., offering an opportunity to analyze hematological variations in patients with anemia. …”
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Xpert Ultra stool testing to diagnose tuberculosis in children in Ethiopia and Indonesia: a model-based cost-effectiveness analysis by Peter J Dodd, Nyashadzaishe Mafirakureva, Rina Triasih, Debebe Shaweno, Jens Levy, Eveline Klinkenberg, Petra de Haas, Ineke Spruijt, Nastiti Kaswandani, Ahmed Bedru, Melaku Gebremichael, Edine W Tiemersma

“…We based model parameters on ongoing studies and surveillance, systematic literature review, and expert opinion. We estimated costs using data available publicly and obtained through in-country expert consultations. …”
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High speciation in the cryptic Pristimantis celator clade (Anura: Strabomantidae) of the Mira river basin, Ecuador-Colombia by Mario H. Yánez-Muñoz, Juan P. Reyes-Puig, Carolina Reyes-Puig, Gabriela Lagla-Chimba, Christian Paucar-Veintimilla, Miguel A. Urgiles-Merchán, Julio C. Carrión-Olmedo

“…This study focuses on the phylogenetic and systematic revision of a frog clade initially labeled as Pristimantis verecundus, revealing significant cryptic diversity. …”
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Building on and tailoring to: Adapting a cancer caregiver psychoeducational intervention for rural settings by Erin E. Kent, Kelly R. Tan, Zev M. Nakamura, Jesse Kovacs, Mindy Gellin, Allison Deal, Eliza M. Park, Maija Reblin

“…Additional systemic challenges, including lack of systematic documentation of caregivers, persist and may especially disadvantage under‐represented and underserved groups, such as rural dwellers. …”
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Quantification of Myocardial Biomarkers in Sudden Cardiac Deaths Using a Rapid Immunofluorescence Method for Simultaneous Biomarker Analysis by Matteo Antonio Sacco, Valerio Riccardo Aquila, Saverio Gualtieri, Roberto Raffaele, Maria Cristina Verrina, Lucia Tarda, Santo Gratteri, Isabella Aquila

“…Conclusions: This study supports the potential use of cardiac markers, particularly TnI, in peripheral blood for postmortem SCD diagnosis, emphasizing the importance of rapid and systematic analysis to minimize hemolysis-related variability. …”
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Determinants of Diabetic Nephropathy among Diabetic Patients in General Public Hospitals of Tigray, Ethiopia, 2018/19 by Teklewoini Mariye Zemicheal, Degena Bahrey Tadesse, Hagos Tasew Atalay, Girmay Teklay Weldesamuel, Gebrewahd Bezabh Gebremichael, Haben Nuguse Tesfay, Teklehaimanot Gereziher Haile

“…An interviewer-administered questionnaire was employed for data collection, and a systematic sampling technique was used to select the study participants. …”
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Challenges and enablers for scaling up interventions targeting non-communicable diseases: a qualitative study applying the Consolidated Framework for Implementation Research to 19... by Josefien van Olmen, Peter Delobelle, Meena Daivadanam, Hassan Haghparast-Bidgoli, Maria Lazo-Porras, J Jaime Miranda, Yuan Li, Rohina Joshi, Amanda G Thrift, Rajesh Vedanthan, Gina Agarwal, Mark D Huffman, Kerstin Klipstein-Grobusch, Naomi Levitt, Dike Ojji, Feng J He, Kamran Siddiqi, Pascal Geldsetzer, Puhong Zhang, Milena Soriano Marcolino, Lal B Rawal, Brian Oldenburg, Helena Teede, Josephine Birungi, Edwin Wouters, Abha Shrestha, Ari Probandari, Mayowa Owolabi, Vilma Irazola, Andrea Beratarrechea, Keiko Nakamura, Gindo Tampubolon, Zulma Ortiz, Violet Naanyu, Jaap Koot, Anusha Ramani-Chander, Stephen Sherwood, Monika Martens, Gade Waqa, Maria Eugenia Esandi, Sujarwoto Sujarwoto, Laura Antonietti, Jan-Walter De Neve, Sayoki G Mfinanga, Antonio Luiz Pinho Ribeiro

“…Generated themes were mapped systematically to four out of five domain categorisations of the Consolidated Framework for Implementation Research (CFIR); the innovation domain fell outside the scope of this study.Results Highlighted findings using CFIR are: (i) outer setting: influence of politics, lack of coordination between government departments and differing agendas towards NCDs hindered implementation while reliable and trustworthy government connections proved useful; (ii) inner setting: commitment of resources for implementation was a challenge while research capacity, work culture and trustworthy networks facilitated implementation; (iii) individuals: high-level stakeholder support and leadership was essential; (iv) process: extensive time and efforts required for stakeholder engagement towards local contextualisation was challenging, while collaborating, joint reflection, effective communication and adaptation facilitated. …”
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Life history, reproductive, and demographic parameters for bottlenose dolphins (Tursiops truncatus) in Sarasota Bay, Florida by Randall S. Wells, Aleta A. Hohn, Michael D. Scott, Jay C. Sweeney, Forrest I. Townsend, Jason B. Allen, Aaron A. Barleycorn, Katherine A. McHugh, Kim Bassos-Hull, Gretchen N. Lovewell, Deborah A. Duffield, Cynthia R. Smith, A. Blair Irvine

“…Detailed histories have been collected for resident individuals through integrated observations, systematic photographic identification surveys, tagging and tracking, catch-and-release health assessments, remote biopsy sampling, and stranding response. …”
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Metabolic reprogramming and immunological changes in the microenvironment of esophageal cancer: future directions and prospects by Zhi-Xun Guo, Jia-Li Ma, Jin-Qiu Zhang, Ling-Ling Yan, Ying Zhou, Xin-li Mao, Xin-li Mao, Xin-li Mao, Shao-Wei Li, Shao-Wei Li, Shao-Wei Li, Xian-Bin Zhou, Xian-Bin Zhou, Xian-Bin Zhou

“…We analyzed and discussed these studies, while also expressing our own insights and opinions.ResultsA total of 137 articles were included in the review: 21 articles focused on the tumor microenvironment of esophageal cancer, 33 delved into research related to glucose metabolism and tumor immunology, 30 introduced amino acid metabolism and immune responses, and 17 focused on the relationship between lipid metabolism in the tumor microenvironment and both tumor cells and immune cells.ConclusionThis article delves into metabolic reprogramming and immune alterations within the TME of EC, systematically synthesizes the metabolic characteristics of the TME, dissects the interactions between tumor and immune cells, and consolidates and harnesses pertinent immunotherapy targets, with the goal of enhancing anti-tumor immunotherapy for esophageal cancer and thereby offering insights into the development of novel therapeutic strategies.…”
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