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    Improvement of the dissolution of the antineoplastic drug regorafenib through impregnation into pullulan polysaccharide using supercritical fluid technology: Optimization of the pr... by Ali Sheikhi, Sepideh Hamedi, Gholamhossein Sodeifian, Fariba Razmimanesh

    Published 2025-03-01
    “…This study explores the impregnation of regorafenib monohydrate (REG MH) into pullulan (PULL) using supercritical carbon dioxide (scCO2), aiming to promote the oral bioavailability, water solubility and therapeutic efficacy of the drug. …”
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