Patients with Liver Cirrhosis as Frequent Attenders of Emergency Departments by Chen-Ju Chuang, Yi-Fang Wu, Kai-Hsiang Wu, Yi-Chuan Chen

“…Most studies regarding frequent attenders of EDs examine general patients without classifying certain subgroups. This study aimed to investigate patients with liver cirrhosis who present repeatedly to the ED. …”
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Rheumatoid factor isotypes in rheumatoid arthritis diagnosis and prognosis: a systematic review and meta-analysis by Nicola Bizzaro, Franco Franceschini, Maria Infantino, Carlo Selmi, Gian Domenico Sebastiani, Francesca Motta, Davide Giavarina, Boaz Palterer

“…The study of RF isotypes has further attempted to improve diagnostic accuracy and identify specific subgroups of patients. The main objective of this study is to provide an analysis of the literature on the role of RF isotypes in the diagnosis and prognosis of rheumatoid arthritis (RA).Methods We performed a systematic literature review and meta-analysis on the role of RF isotypes in RA (only in English, from PubMed, search terms: “rheumatoid factor isotypes”, “diagnosis”, “prognosis” and “rheumatoid arthritis”, last search 31 July 2022, two independent assessment of quality and biases, results included in tables and in the meta-analysis).Results Thirty-six articles were examined (7517 patients). …”
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Identification of Bacterial Lipopolysaccharide-Associated Genes and Molecular Subtypes in Autism Spectrum Disorder by He Y, He Y, Cheng B

“…This research aims to explore bacterial lipopolysaccharide (LPS)- and immune-related (BLI) molecular subgroups in ASD to enhance understanding of the disorder.Methods: We analyzed 89 control samples and 157 ASD samples from the GEO database, identifying BLI signatures using least absolute shrinkage and selection operator regression (LASSO) and logistic regression machine learning algorithms. …”
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PATIENTS' CHRONOTYPE INFLUENCE IN TREATMENT EFFICIENCY OF PLACENTA CRYERXTRACT CHANGES IN MAXILLOFACIAL PHLEGMONS by K. Lokes, M. Pérez Sayáns, V. Lychman, D. Steblovskyi, I. Boiko, D. Avetikov

“…These patients were divided into three clinical groups, each comprising 30 individuals, further categorized into two subgroups based on circadian rhythms. Analyzing the obtained data, it can be asserted that the most significant changes in markers of lipid peroxidation in patients with superficial phlegmons of maxillofacial localization were experienced in both experimental groups when used against the background of treatment according to standard protocols of intravenous injections of the cryopreserved placenta without and in combination with local injection of the cryopreserved placenta as part of "Levomekol" ointment, in contrast to the control group. …”
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Higher Life’s Crucial 9 protects against infertility among U.S. women aged 18–45 years by Shaoqun Huang, Shuqin Duan, Seok Choi, Hongyang Gong

“…Interaction analyses were conducted on subgroups to validate the findings.ResultsThere was a significant negative association between LC9 and infertility. …”
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Policies, programmes and research on adolescent and youth sexual and reproductive health in South Sudan: a systematic scoping review by Neha S Singh, Jessica Crawford, Chirrilo Madut, Chol Bak, Zack Wol

“…Vulnerable populations were excluded from research, policies and programmes, including very young adolescents, LGBTQ youth and youth with disabilities.Conclusions Quality research has been done on AYSRH in South Sudan; however, there are many key areas that have not been addressed such as maternal mortality and morbidities, safe abortion and tailored interventions for specific subgroups. While some policies and programmes were identified that address AYSRH, robust programme evaluation processes or evidence of follow-through or implementation of government strategies are lacking.…”
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Association of Red Blood Cell Distribution Width With Carotid–Femoral Pulse Wave Velocity in a Southern Chinese Population by Xing Yu, Yali Huang, Yunyun Su, Liangdi Xie

“…Participants were stratified into four subgroups based on RDW quartiles: Q1 (RDW ≤ 12.80%), Q2 (12.80% < RDW ≤ 13.40%), Q3 (13.40% < RDW ≤ 14.10%), and Q4 (RDW > 14.10%). …”
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Assessment of Zinc Alpha-2 Glycoprotein Level in Gestational Diabetes Woman in Respect to Glycemic Status with and without Treatment by Bara Nahdh Saleem, Manal Khalid Abdulridha, Hind Abdalkhaliq Showman, Manal Sabbar

“…Significant variation in ZAG levels was observed among subgroups of treated GDM pregnant women (p<0.01). The metformin group exhibited the lowest level of ZAG. …”
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Access to Diagnostics and Treatment for People With Metastatic EGFR-Positive NSCLC: Lessons From Project PRIORITY by Jill Feldman, MA, Ivy Elkins, MBA, Zofia Piotrowska, MD, Bellinda L. King-Kallimanis, PhD, Tendai Chihuri, MD, Carly Johnson, BS, Alecia Clary, PhD, Teri Kennedy, MA, Upal Basu Roy, PhD, MPH

“…Descriptive statistics were used and included subgroups based on residency and cancer stage. Results: Of the 425 participants, most were female (67%), under 60 years old (53%), and resided in the United States (74%). …”
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Cost-Effectiveness of the Prenatal Detection of Congenital Heart Diseases: A Systematic Literature Review by Darío Londoño Trujillo, Paula A. Castro García, Kristian K. Rojas López, Karen J. Moreno-Medina, María T. Dominguez Torres, Rodolfo J. Dennis Verano, Nestor F. Sandoval Reyes

“…**Discussion:** While recent cost-effectiveness analyses demonstrated improved methodological quality, there was a lack of homogeneity due to differences in comparators and population subgroups analyzed. Despite this heterogeneity, fetal ultrasonography screening was consistently identified as a cost-effective strategy, with its cost-effectiveness heavily influenced by the expertise of the interpreting physician. …”
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The Anti-Inflammatory Effect of Chenopodium Murale in Comparison to Salvia Frigida on Atopic Eczema by Zahraa Y. Hassan, Tuka Y. Hassan, Ahmed Y. Kanany

“…Fifty mice were included in the study, subdivided equally into five subgroups [control, induction, Tacrolimus-1%, Phytosterol-3%, and Phenolic-5%]. …”
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The Obesity Paradox Revisited: Is Obesity Still a Protective Factor for Patients With High Comorbidity Burden or High-Complexity Procedures? by Hyo Jin Son, BSc, Denise W. Gee, MD, David Gomez, MD, PhD, James J. Jung, MD, PhD

“…Then, we investigated the subgroups stratified by procedural complexity and comorbidity burden using a modified Charlson Comorbidity Index (mCCI) and mortality probability. …”
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Association between triglyceride-glucose index and carotid atherosclerosis in Chinese steelworkers: a cross-sectional study by Haoyue Cao, Qinglin Li, Juxiang Yuan

“…The association between TyG and CAS was evaluated across different subgroups, including sex, age, lifestyle, medical history, and the state of occupational exposure. …”
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Thrombin Generation in Acute Ischaemic Stroke by Ibrahim O. Balogun, Lara N. Roberts, Raj Patel, Rohan Pathansali, Lalit Kalra, Roopen Arya

“…The result was reproduced in multiple comparisons between acute ischaemic stroke subgroups and normal healthy volunteers. Endogenous thrombin potential and peak thrombin did not indicate hypercoagulability after acute ischaemic stroke, and thrombolytic therapy did not affect thrombin generation assays. …”
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Expression study of Wnt/β-catenin signaling pathway associated lncRNAs in schizophrenia by Fatemeh Manafzadeh, Behzad Baradaran, Seyed Gholamreza Noor Azar, Kamran Javidi Aghdam, Reza Dabbaghipour, Asghar Shayannia, Soudeh Ghafouri-Fard

“…ROC curve analysis revealed that DANCR, PTCSC3, SNHG5, and CCAT2 genes had diagnostic power with specificity and sensitivity of 80% and above in separation between study subgroups. In brief, our data demonstrated dysregulation of Wnt/β pathway related genes and lncRNAs in the peripheral blood of patients with schizophrenia and their potential as biomarkers for this disorder.…”
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High-density lipoprotein cholesterol as a prognostic marker for 90-day transplant-free mortality in hepatitis B virus-related acute-on-chronic liver failure by Ke Shi, Yi Zhang, Yanqiu Li, Xiaojing Wang, Ying Feng, Xianbo Wang

“…In the training cohort, the 90-day TF mortality rates were 8.3%, 15.2%, 24.0%, and 43.2% for the extremely low, low, medium, and high-risk subgroups, respectively, while in the validation cohort, they were 4.5%, 18.5%, 31.2%, and 44.7%, respectively.ConclusionsHDL-C levels &lt; 0.13 mmol/L were associated with increased 90-day transplant-free mortality in patients with HBV-ACLF. …”
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Altered association between cortisol and adrenocorticotropic hormone levels in the early stage of type 2 diabetic ketoacidosis by Liang Wang, Xiaomei Meng, Yuxiao Tang, Yaping Hao

“…Multiple stepwise regression analysis showed that for all DKA patients and for subgroups with and without infection, the cortisol level at admission was independently positively correlated with the ACTH level and negatively correlated with the bicarbonate level (both P&lt;0.01).ConclusionsIn the early stage of DKA, a phenomenon of altered association between cortisol–ACTH occurs and is especially prominent in DKA patients with infection. …”
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THE STRUCTURE OF THE SIBERIAN GEOGRAPHICAL FLORAL ELEMENT IN THE MIDDLE SIBERIAN FOREST STEPPES by E. M. Antipova

“…All types of distribution areas were combined into four large subgroups, namely Siberian, West Siberian, Middle Siberian, and East Siberian. …”
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Is There a Relationship between Serum Anti-Mullerian Hormone Levels and Abortion Rates in Patients Who Received In vitro Fertilisation-Embryo Transfer Cycles? by Pinar Karacin, Serdar Dilbaz, Oya Aldemir, Berna Dilbaz, Yaprak Engin Ustun

“…The same analyses were repeated in two subgroups under 34 years of age and above, and no difference was found in terms of miscarriage rates. …”
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Once-weekly semaglutide doubles the five-year risk of nonarteritic anterior ischemic optic neuropathy in a Danish cohort of 424,152 persons with type 2 diabetes by Jakob Grauslund, Andreas Abou Taha, Laleh Dehghani Molander, Ryo Kawasaki, Sören Möller, Kurt Højlund, Lonny Stokholm

“…Given the irreversible nature of NAION, it is important to acknowledge this risk, and upcoming studies should aim to identify high-risk subgroups.…”
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