Age-related cerebral ventriculomegaly occurs in patients with primary ciliary dyskinesia by Franziska Eisenhuth, Joy E. Agbonze, Adam M. R. Groh, Jesse M. Klostranec, David A. Rudko, Jo Anne Stratton, Adam J. Shapiro

“…Patients with PCD displayed significantly larger ventricular areas (p < 0.0001) and Evans index (p < 0.01), indicating ventriculomegaly that was consistent across all genetic subgroups. Ventricular enlargement correlated positively with increasing age in patients with PCD compared to controls (p < 0.001). …”
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Increased Body Mass Index during Therapy for Childhood Acute Lymphoblastic Leukemia: A Significant and Underestimated Complication by Helen C. Atkinson, Julie A. Marsh, Shoshana R. Rath, Rishi S. Kotecha, Hazel Gough, Mandy Taylor, Thomas Walwyn, Nicholas G. Gottardo, Catherine H. Cole, Catherine S. Choong

“…Females treated on standard risk protocols and younger males may be at greatest risk of becoming obese during treatment for ALL. These subgroups may benefit from intervention strategies to manage BMI during treatment for ALL.…”
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Association of dietary niacin intake with osteoporosis in the postmenopausal women in the US: NHANES 2007–2018 by Li Li, Wankun Liang, Bing Deng, Yue Jiang, Xiaomin Huang, Yanlin Zhang, Tianrui Lu, Lu Wang, Yunxiang Xu, Guizhen Chen

“…Additionally, we performed stratified and interaction analyses to illustrate the stability of the observed relationships across different subgroups.ResultsAfter adjusting for all covariates, there was a significant inverse association with osteoporosis (OR = 0.87; 95% CI: 0.77–0.97; p = 0.016). …”
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Predictive role of ABC transporters in the efficacy of enfortumab vedotin for urothelial carcinoma by Toshiki Kijima, Atsuko Takada‐Owada, Hiroki Shimoda, Hidetoshi Kokubun, Toshitaka Uematsu, Kohei Takei, Hironori Betsunoh, Masahiro Yashi, Kazuyuki Ishida, Takao Kamai

“…Progression‐free survival (PFS) was estimated using the Kaplan–Meier method, and differences between subgroups (e.g., Nectin‐4 and ABC transporter expression) were compared using the log‐rank test. …”
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Emergent Biomarkers of Residual Cardiovascular Risk in Patients with Low HDL-c and/or High Triglycerides and Average LDL-c Concentrations: Focus on HDL Subpopulations, Oxidized LDL... by Filipa Mascarenhas-Melo, Filipe Palavra, Daniela Marado, José Sereno, Edite Teixeira-Lemos, Isabel Freitas, Maria Isabel-Mendonça, Rui Pinto, Frederico Teixeira, Flávio Reis

“…Patients with cardiovascular risk factors (n=169) were divided into 4 subgroups, combining normal and low HDL-c with normal and high TGs patients. …”
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Longitudinal relationship between baseline Weight-Adjusted Waist Index and stroke risk over 8 years in Chinese adults aged 45 and older: a prospective cohort study by Xiaoqiang Li, Xiangmao Zhou, Hui Du, Hui Wang, Zhijian Tan, Yaqing Zeng, Zhibin Song, Guifeng Zhang

“…Curve fitting revealed a linear relationship between WWI and stroke risk, consistent across various demographic and clinical subgroups.ConclusionHigher WWI is linked to an increased risk of stroke in aged 45 and older Chinese adults over an eight-year period. …”
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Impact of aspirin on biochemical recurrence of prostate cancer after robot assisted radical prostatectomy in a multicenter retrospective cohort study by Shuhei Suzuki, Hiromitsu Negoro, Masashi Kubota, Takayuki Sumiyoshi, Ryoichi Saito, Tomoya Okuno, Takehiko Segawa, Shigeki Fukuzawa, Hiroyuki Onishi, Kodai Hattahara, Kanji Nagahama, Yuya Sekine, Ryoma Kurahashi, Kimihiro Shimatani, Atsuro Sawada, Shusuke Akamatsu, Hiroyuki Nishiyama, Takayuki Goto, Takashi Kobayashi

“…In the analysis of high-risk subgroups, patients in the aspirin group with an ISUP (International Society of Urological Pathology) grade ≥ 4 had a significantly lower recurrence rate in both matched groups (PSM, hazard ratio 0.44, 95% CI 0.22–0.88; MDM, hazard ratio 0.45, 95% CI 0.23–0.90). …”
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The Polymorphism −308G/A of Tumor Necrosis Factor-α Gene Modulates the Effect of Immunosuppressive Treatment in First Kidney Transplant Subjects Who Suffer an Acute Rejection by Ana Isabel Sánchez-Fructuoso, Isabel Pérez-Flores, Rosalia Valero, Maria Angeles Moreno, Miguel Fernandez-Arquero, Elena Urcelay, Cristina Fernández-Pérez, Jose Luis Santiago

“…A retrospective analysis of 439 first kidney recipients randomly divided into two subgroups (discovery and validation cohorts) was performed to identify the best predictors of acute rejection (AR). …”
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Obesity Severity, Dietary Behaviors, and Lifestyle Risks Vary by Race/Ethnicity and Age in a Northern California Cohort of Children with Obesity by Margaret C. Ford, Nancy P. Gordon, Amanda Howell, Cheryl E. Green, Louise C. Greenspan, Malini Chandra, R. Grant Mellor, Joan C. Lo

“…Unhealthy dietary behaviors, screen time, limited exercise, and sleep were more prevalent in older children and in selected black, Hispanic, and Asian subgroups, where consumption of sweetened beverages or juice was especially high. …”
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A Bioclinical Pattern for the Early Diagnosis of Cardioembolic Stroke by Bruno Zecca, Clara Mandelli, Alberto Maino, Chiara Casiraghi, Giovanbattista Bolla, Dario Consonni, Paola Santalucia, Giuseppe Torgano

“…Patients with cardioembolic stroke had significantly higher levels of NT-proBNP and lower globulin/albumin (G/A) ratio compared with the other subgroups. At multiple logistic regression NT-proBNP>200 pg/mL, G/A ratio>0.70, and NIHSS score were independent predictors of cardioembolic stroke with high accuracy of the model, either including (AUC, 0.91) or excluding (AUC, 0.84) atrial fibrillation. …”
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Cardiac Function in Long-Term Survivors of Childhood Lymphoma by Mark K. Friedberg, Ido Solt, Myriam Weyl-Ben-Arush, Yulia Braver, Avraham Lorber

“…Further comparisons were made between lymphoma subgroups and between males and females. Results. Mean age at diagnosis was 9.1 years. …”
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Assessment of cardiac iron deposition and genotypic classification in pediatric beta-thalassemia major: the role of cardiac MRI by Siqi Zhang, Wen Zhao, Longwei Sun, Guohua Liang, Xiaodong Wang, Hongwu Zeng

“…The patients were classified into three genetic subgroups of β0/β0, β0/β+, and β+/β+ based on their genetic outcomes. …”
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Effectiveness of cognitive–behavioural therapy: a protocol for an overview of systematic reviews and meta-analyses by Sarah E Lamb, Shona Kirtley, Beth Fordham, Thavapriya Sugavanam, Sally Hopewell, Karla Hemming, Jeremy Howick, Roshan das Nair, Julia Hamer-Hunt

“…The evidence will be mapped and synthesised where appropriate by health problem, patient subgroups, intervention type, context and outcome.Ethics and dissemination Ethical approval is not required as this is an overview of published systematic reviews. …”
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Cosmetic Outcome Assessment following Breast-Conserving Therapy: A Comparison between BCCT.core Software and Panel Evaluation by Max Hendrik Haloua, Nicole Marianna Alexandra Krekel, Gerrit Johannes Albertus Jacobs, Barbara Zonderhuis, Mark-Bram Bouman, Marlon Eugène Buncamper, Franciscus Bernardus Niessen, Henri Adolf Hubert Winters, Caroline Terwee, Sybren Meijer, Monique Petrousjka van den Tol

“…By contrast, analysis of the evaluation of scar tissue revealed large discrepancies between the BCCT.core software and the panel. The analysis of subgroups formed from different combinations of the panel members still showed substantial agreement with the BCCT.core software (range 0.64–0.69), independent of personal background. …”
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A protocol to optimize non-invasive brain stimulation for post-stroke rehabilitation by Ayesha Juhi, Manul Das, Dinesh Bhatia, Suman Dhaka, Rajesh Kumar, Deepak Kumar, Shreya Sharma, Pritam Kumar Chaudhary, Chanchal Goyal, Md Asif Khan, Himel Mondal

“…. • Hemodynamically stable post-stroke patients randomized in four groups in rTMS and tDCS each and their baseline cognitive and motor function assessed • Application of the two types of therapy for 6 weeks • Checking improvement of cognitive and motor function and compare the improvement among subgroups of recipient of various frequencies and currents…”
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KRAS, p53 and BRAF Gene Mutations and Aneuploidy in Sporadic Colorectal Cancer Progression by Daniele Calistri, Claudia Rengucci, Ian Seymour, Elena Leonardi, Mauro Truini, Davide Malacarne, Patrizio Castagnola, Walter Giaretti

“…We previously investigated a limited number of human sporadic colorectal cancers (CRCs) and observed a statistically different occurrence of KRAS and p53 mutations among predetermined subgroups of tumors with different degrees of DNA aneuploidy. …”
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Prognostic Factors of Radiofrequency Ablation plus Systemic Chemotherapy for Unresectable Colorectal Cancer with Liver Metastasis by Ky Thai Doan, Long Nguyễn Việt, Thinh Nguyen Tien, Binh Nguyen Canh, Hoai Ngo Thi, Ngoc Nguyen Thanh, Bieu Bui Quang, Quang Le Van, Hyun Woong Lee, Bang Mai Hong

“…Survival analyses were conducted using the Kaplan-Meier method, and the log-rank test was used to characterize differences in the median survival time and the 1-year, 3-year, and 5-year overall survival rates of subgroups to identify prognostic factors. Results. …”
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Genetic association study of TERT gene variants with chronic kidney disease susceptibility in the Chinese population by Yan Su, Yuan Feng, Xinran Lin, Chunyang Ma, Jiali Wei

“…Stratification analysis indicated that rs4635969 was related to an increased risk of CKD in different subgroups (age ≤ 50 years and male). MDR analysis indicated that the two-site model (rs2735940 and rs4635969) was the best prediction model. …”
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Donor Identification, Genetic Diversity, Population Structure and Marker–Trait Association Analyses for Iron Toxicity Tolerance Using Rice Landraces by Debanjana Saha, Udit Nandan Mishra, Chittaranjan Sahoo, Seema Tripathy, Uttam Kumar Behera, Susmita Das, Chandrasekhar Sahu, Shiv Datt, Manoj Kumar Rout, Tanmaya Lalitendu Mohanty, Shakti Prakash Mohanty, Saumya Ranjan Barik, Ishwar Chandra Mohanty, Sharat Kumar Pradhan

“…Utilizing STRUCTURE software, a total of four genetic structure groups were detected in the panel germplasm of lines. These structural subgroups exhibited good correlations among their members for iron toxicity tolerance and other yield-related traits. …”
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A New Weak Chelator in Endodontics: Effects of Different Irrigation Regimens with Etidronate on Root Dentin Microhardness by Talita Tartari, Patrícia de Almeida Rodrigues Silva e Souza, Bruno Vila Nova de Almeida, José Otávio Carrera Silva Júnior, Oscar Facíola Pessoa, Mario Honorato Silva e Souza Junior

“…After measurements, the G3 samples were distributed into subgroups G4, G5, and G6, which were submitted to 17% EDTA, 10% CA and 9% HEBP, respectively. …”
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