Stability of miR-126 in Urine and Its Potential as a Biomarker for Renal Endothelial Injury with Diabetic Nephropathy by Yang Liu, Guangqiang Gao, Chun Yang, Kun Zhou, Baozhong Shen, Hongyan Liang, Xiaofeng Jiang

“…Stability of urinary miR-126 and factors that affected the stability were assessed. A subgroup analysis was also carried out to compare the urinary miR-126 level in T2DM patients well controlled by the treatment versus those who were not well controlled. …”
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Lipid Metabolism-Related Gene Signature Predicts Prognosis and Indicates Immune Microenvironment Infiltration in Advanced Gastric Cancer by Lijian He, Qiange Ye, Yanmei Zhu, Wenqi Zhong, Guifang Xu, Lei Wang, Zhangding Wang, Xiaoping Zou

“…The high-risk score predicted poor prognosis and indicated low degree of immune infiltration. Subgroup analysis showed that the risk model was an independent predictor of prognosis in AGC. …”
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Inhaled corticosteroids in asthma and chronic obstructive pulmonary disease combined phenotype: when to use and what to expect? by Srishankar Bairy, Tarun Tiwari, Himanshu Mittal, Neeraj Gupta, Meghana M

“…Although the number of exacerbations decreased during the study period in this subgroup, this reduction did not reach statistical significance. …”
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Understanding the impact of racism on surgical outcomes in settler nation-states USA and Canada: a protocol for a systematic review and meta-analysis by Mary Brindle, Oluwatomilayo Daodu, Tyara Marchand, Saffa Aziz, Ifeoluwa Adedipe, Mirna Matta

“…Heterogeneity in these estimates will be examined using subgroup analyses and meta-regression.Ethics and dissemination This study uses secondary data and, therefore, does not require ethics approval. …”
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Association between impaired brachial flow-mediated dilation and early neurological deterioration in acute ischemic stroke: a retrospective analysis by Sang Hee Ha, Bo Hye Yoon, Bon Gook Koo, Dong Hoon Shin, Yeong-Bae Lee, Bum Joon Kim

“…Multivariate analysis revealed that a history of stroke (adjusted odds ratio [aOR] = 1.728; 95% confidence interval [CI] 1.159–2.578; P = 0.007) and low % were independently associated with END. Subgroup analysis revealed that low %FMD was significantly associated with END within the small vessel disease (SVD) category (aOR = 0.789; 95% CI 0.679–0.920; P = 0.002). …”
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Platelet-to-lymphocyte ratio as a biomarker of systemic inflammation in systemic lupus erythematosus: A meta-analysis and systematic review. by Young Ho Lee, Gwan Gyu Song

“…Upon stratification by ethnicity, an elevated PLR was observed in the SLE group among both Asian and Arab populations. Subgroup analysis based on sample size revealed consistently higher PLR in both small (n < 200) and large sample (n ≥ 200) SLE groups. …”
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The addition of vitamin E could reduce femoral head penetration of the polyethylene liners by Fanxiao Liu, Ling Gao, Dawei Wang, Qingyu Zhang

“…The pooled results revealed significant decreased FHP at the last follow-up (pooled Mean Difference [MD] = -0.10, 95% confidence intervals [CIs]: -0.14 to -0.06). The subgroup analysis revealed a consistent trend at different time points during the follow-up. …”
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Prognostic Role of Platelet-to-Lymphocyte Ratio in Hepatocellular Carcinoma with Different BCLC Stages: A Systematic Review and Meta-Analysis by Wan-fu Lin, Mao-feng Zhong, Yu-ren Zhang, Huan Wang, He-tong Zhao, Bin-bin Cheng, Chang-quan Ling

“…An elevated pretreatment PLR indicated unfavorable worse OS (HR = 1.73; 95% CI: (1.46, 2.04); P<0.00001) and DFS (HR = 1.30; 95% CI: (1.06, 1.60); P=0.01). Subgroup analysis indicated that high PLR indicated poor OS among BCLC-B/C patients without heterogeneity, while PLR in BCLC-A patients indicated high statistical heterogeneity with I2 value of 78%. …”
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ADIPOQ rs2241766 Gene Polymorphism and Predisposition to Diabetic Kidney Disease by Qiuxia Han, Wenjia Geng, Dong Zhang, Guangyan Cai, Hanyu Zhu

“…After stratification analyses by ethnicity and disease type, a similar trend was also revealed in the Caucasian and African subgroups as well as in the type 2 diabetes mellitus (T2DM) subgroup. …”
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Association between the exposure to brominated flame retardants and psoriasis risk among U.S. adults: A population-based study by Jingbo Zhang, Xiangyun Shi, Genlong Bai, Jin Chen, Yidian Fu, Aijun Chen

“…Moreover, the association between PBB153 and psoriasis risk remained stable across all subgroup analyses, including those stratified by gender. …”
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The Comparison of Diagnostic Ability between Blue Laser/Light Imaging and Narrowband Imaging for Sessile Serrated Lesions with or without Dysplasia by Reo Kobayashi, Naohisa Yoshida, Yukiko Morinaga, Hikaru Hashimoto, Yuri Tomita, Satoshi Sugino, Ken Inoue, Ryohei Hirose, Osamu Dohi, Takaaki Murakami, Yutaka Inada, Yasutaka Morimoto, Yoshito Itoh

“…Materials and Methods. This was a subgroup analysis of prospective studies. 476 suspiciously serrated lesions of ≥2 mm on the proximal colon showing serrated change with magnified NBI or BLI in our institution between 2014 and 2021 were examined histopathologically. …”
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A 2-Year, Phase IV, Multicentre, Observational Study of Ranibizumab 0.5 mg in Patients with Neovascular Age-Related Macular Degeneration in Routine Clinical Practice: The EPICOHORT... by Sergio Pagliarini, Stephen Beatty, Blandina Lipkova, Eduardo Perez-Salvador Garcia, Stefaan Reynders, Margarita Gekkieva, Abdelkader Si Bouazza, Stefan Pilz

“…The observed decline in mean BCVA (Month 12, +1.5; Month 24, –1.3 letters) may be associated with undertreatment as suggested by BCVA subgroup analysis. Conclusion. The EPICOHORT study conducted in routine clinical practice reinforces the well-established safety profile of ranibizumab in nAMD. …”
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Sodium-glucose cotransporter-2 inhibitors increase urinary tract infections?—a cross sectional analysis of a nationwide Japanese claims database by Go Anan, Daisuke Kikuchi, Kenji Omae, Takuo Hirose, Kouji Okada, Takefumi Mori

“…Among female patients with DM, there was no significant difference in the incidence of UTIs with or without an SGLT2 inhibitor prescription (OR, 0.99; 95% CI, 0.96–1.01). Subgroup analyses by age confirmed similar relationships between SGLT2 inhibitor prescriptions and UTIs, except for female patients aged ≤39 years, in whom SGLT2 inhibitor prescription was negatively associated with the likelihood of developing UTIs. …”
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Risk of adverse cardiovascular events following spinal cord injury in patients with osteoporosis: Real-world evidence by Shih-Kai Kao, Yu-Ting Yu, Ming-Hsien Tsai

“…Furthermore, mortality risk is higher in individuals with SCI, particularly those with pathological fracture. Subgroup analyses based on sex and age supported these findings. …”
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Smoking Exposure and Survival of Patients with Esophagus Cancer: A Systematic Review and Meta-Analysis by Jun-jie Kuang, Zhi-min Jiang, Yan-xian Chen, Wei-peng Ye, Qiong Yang, Hui-zhong Wang, De-rong Xie

“…In the grouping analysis, among esophageal squamous-cell carcinoma patients, current and former smokers, compared to those who have never smoked, seemed to have a poorer prognosis (HR = 1.41, 95% CI 1.22–1.64, and HR = 1.35, 95% CI 0.92–1.97, resp.). In the subgroup analysis, adverse effects on current smoker compared with never smoker were also observed in China and the other countries (HR = 1.5, 95% CI 1.18–1.92, and HR = 1.36, 95% CI 1.12–1.65, resp.). …”
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Chronic Liver Disease in Ethiopia with a Particular Focus on the Etiological Spectrums: A Systematic Review and Meta-Analysis of Observational Studies by Behailu Terefe Tesfaye, Temesgen Mulugeta Feyissa, Azmeraw Bekele Workneh, Esayas Kebede Gudina, Mengist Awoke Yizengaw

“…We used the DerSimonian-Laird random-effects models to perform the meta-analysis. We conducted subgroup and meta-regression analyses to account for the heterogeneity of the estimates. …”
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Pretransplant HbA1c Is a Useful Predictor for the Development of New-Onset Diabetes in Renal Transplant Recipients Receiving No or Low-Dose Erythropoietin by Kazuaki Tokodai, Noritoshi Amada, Izumi Haga, Atsushi Nakamura, Toshiaki Kashiwadate, Naoki Kawagishi, Noriaki Ohuchi

“…To avoid the strong influence of high-dose erythropoietin on HbA1c levels, we performed subgroup analyses on 85 patients receiving no or low-dose (≤6000 IU/week) erythropoietin. …”
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Safety and performance of oropharyngeal muscle strength training in the treatment of post-stroke dysphagia during oral feeding: protocol for a systematic review and meta-analysis by Xin Wang, Ying Wang, Fenghua Zhou, Minxing Gao, Lingyuan Xu, Heying Wang, Jinan Song, Xiaoqiu Yang

“…Next, quantitative or qualitative, subgroup and sensitivity analyses of the included literature data will be performed as appropriate.Ethics and dissemination Ethical approval is not required for this systematic review as no primary data collection will be required. …”
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Severe Symptomatic Primary CMV Infection in Inflammatory Bowel Disease Patients with Low Population Seroprevalence by Catherine Rowan, Ciaran Judge, Mary D. Cannon, Garret Cullen, Hugh E. Mulcahy, Elizabeth Ryan, Cillian F. De Gascun, Glen A. Doherty

“…Seroprevalence of IgG to CMV, indicating prior exposure, in a subgroup of IBD patients (n=80) was 30.5% and increased with age. …”
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Cross-sectional association between plasma aldosterone concentration and cognitive performance by mini-mental state examination in community dwellers by Aketilieke Nusufujiang, Mulalibieke Heizhati, Nanfang Li, Ling Yao, Wenbo Yang, Hui Wang, Mei Li, Lin Gan, Adalaiti Maitituersun, Miaomiao Liu, Qiaolifanayi Nuermaimaiti, Li Cai, Xiayire Aierken, Xiufang Li, Qin Luo, Jing Hong

“…Multi-variable linear and logistic regression were used to explore the association between log PAC and log MMSE score, and between tertiled PAC (the higher PAC as the exposure) and low cognitive performance, respectively, in total, apparently healthy and diseased participants. Subgroup analyses also were performed by age, gender, BMI, living region, ethnicity and education attainment status.Results27,707 subjects were included, of whom, 12,862 were apparently healthy and 14,845 had disease. …”
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