Circulating Tissue Inhibitor of Matrix Metalloproteinase-4 (TIMP-4) in Systemic Sclerosis Patients with Elevated Pulmonary Arterial Pressure by Gialafos J. Elias, Moyssakis Ioannis, Psaltopoulou Theodora, Papadopoulos P. Dimitrios, Perea Despoina, Vlasis Kostantinos, Kostopoulos Charalampos, Votteas Vassilios, Sfikakis P. Petros

“…TIMP-4, but not MMP-9, levels were significantly raised in patients with SSc than controls. However, in the subgroup of patients with PASP measurements lower to 40 mmHg (n=69), TIMP-4 levels were comparable to controls irrespective of the presence of diffuse or limited skin involvement, or lung fibrosis. …”
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Pediatric pilonidal sinus disease: Recurrence rates of different age groups compared to adults by Dietrich Doll, Susanne Haas, Ida Kaad Faurschou, Theo Hackmann, Henrike Heitmann, Myriam Braun-Münker, Christina Oetzmann von Sochaczewski

“…Results: Pediatric pilonidal sinus patients have a higher 5-year recurrence rate compared to adults (46 % vs. 11.5 %; p < 0.0001). The subgroup of individuals aged 16–18 years appears to experience recurrences 12 months earlier than those below the age of 16. 46.4 % of all pediatric recurrences occur within 5 years. …”
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Effects on Parental Stress of Early Home-Based CareToy Intervention in Low-Risk Preterm Infants by Giuseppina Sgandurra, Elena Beani, Emanuela Inguaggiato, Jakob Lorentzen, Jens Bo Nielsen, Giovanni Cioni

“…Parents (mother and father) of a subgroup of infants enrolled in the RCT filled out a self-report questionnaire on parenting stress (Parenting Stress Index-Short Form (PSI-SF)) before (T0) and after (T1) the CareToy or Standard Care period (4 weeks), according to the allocation of their preterm infant. …”
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The Expansion of CD25highIL-10highFoxP3high B Regulatory Cells Is in Association with SLE Disease Activity by Zahava Vadasz, Regina Peri, Nasren Eiza, Gleb Slobodin, Alexandra Balbir-Gurman, Elias Toubi

“…B regulatory cells (Bregs) belong to a subgroup of activated B cells tasked with maintaining self-tolerance and preventing autoimmunity. …”
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Perinatal intimate partner violence and breastfeeding practices: A systematic review and meta-analysis protocol. by Zelalem Nigussie Azene, Catherine MacPhail, Lisa Gaye Smithers

“…Statistical analysis will be conducted using STATA/SE version 17, employing random-effects models to calculate pooled effect sizes and assess heterogeneity with I2 and Chi-square tests. Subgroup analyses and meta-regression will explore potential sources of heterogeneity.…”
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The Association between Standardized Serum 25-Hydroxyvitamin D Concentration and Risk of Anemia: A Population-Based Cross-Sectional Study by Yang Zhang, Xiaotong Wang, Jia Wang, Weiwei Hu, Xiaolu Song, Ding Yuan, Xianliang Yan

“…Additionally, the association between serum 25(OH)D concentration and red blood cell (RBC) count and hemoglobin (HB) levels was investigated using generalized additive models with smooth functions. Subgroup analysis also was performed. A total of 29933 individuals were included in our research. …”
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Glutathione-S-Transferase p1 Gene Promoter Methylation in Cell-Free DNA as a Diagnostic and Prognostic Tool for Prostate Cancer: A Systematic Review and Meta-Analysis by Jinghe Ye, Mao Wu, Long He, Peng Chen, Hongtao Liu, Hongwei Yang

“…For prognostic variables, hypermethylation of GSTP1 was associated with shorter survival in PCa (HR = 2.57, 95% CI = 1.30, 5.10), with statistical significance in between-study heterogeneity (I2 = 72%, P=0.006). The results of the subgroup analysis indicated that the heterogeneity of studies may be due to differences in the observed indicators. …”
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Epidemiology of tularemia in the countries of the WHO Eastern Mediterranean Region (EMRO): A systematic review and meta-analysis. by Mohammad Sholeh, Safoura Moradkasani, Saber Esmaeili

“…The human seroprevalence of tularemia in WHO-EMRO countries was 6.2% (95% CI, 4.2 9.2). In the subgroup analysis, anti-F. tularensis antibodies were found in 6.92% and 5.5% of the high-risk individuals and Iran, respectively. …”
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Relation of Vitamin D levels with positive and negative symptoms of schizophrenia – A hospital based cross-sectional comparative study by Soumitra Ghosh, Bikashita Deka

“…Among the positive and negative schizophrenia subgroup, there was no statistically significant difference in Vitamin D levels at means of 16.54 ng/mL and 16.25 ng/Ml, respectively. …”
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Association of education level with mortality in United States - A cross-sectional study by Weihong Chang, Qingping Zeng, Boda Zhou

“…Higher EL was associated with mortality reduction in <65 subgroup, while a risk factor in ≥65 for Accidents Mortality. …”
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Availability, accessibility and activation of mental health services among university students in Africa: a protocol of a mixed-methods systematic review with meta-analysis and met... by Hesborn Wao, Melvin A Wao, Ian Muriithi, Paul Seraii, Jackline Syonguvi

“…We will assess heterogeneity between studies by appropriate subgroup analyses. Publication bias will be detected using funnel plots.Ethics and dissemination Ethical clearance is not required as we are not collecting primary data. …”
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Evaluation of Cognitive Functions in People Living with HIV Before and After COVID-19 Infection by Dimtrios Basoulis, Elpida Mastrogianni, Irene Eliadi, Nikolaos Platakis, Dimitris Platis, Mina Psichogiou

“…A negative correlation was observed between MOCA scores and age (ρ = −0.283, <i>p</i> = 0.002), but not with a CD4 count at diagnosis (ρ = 0.169, <i>p</i> = 0.071) or initial HIV RNA load (ρ = 0.02, <i>p</i> = 0.984). In the subgroup with repeated testing, MOCA was correlated with the CD4 count (ρ = 0.238, <i>p</i> = 0.069 in the first and ρ = 0.319, <i>p</i> = 0.014 second test). …”
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BMI trajectories are associated with NAFLD and advanced fibrosis via aging-inflammation mediation by Haiyang Peng, Zhibo Zhao, Jianping Gong, Kun He

“…The association between rapid ascending trajectory and advanced fibrosis was more pronounced among the male subgroup (p for interaction = 0.008). Conclusion The rapid ascending trajectory of BMI correlates with an increased susceptibility to NAFLD and advanced fibrosis independent of BMI, mediated by aging and inflammation. …”
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The efficacy and safety of fluvoxamine in patients with COVID-19: A systematic review and meta-analysis from randomized controlled trials. by Qiufeng Zhou, Guozheng Zhao, Yu Pan, Ying Zhang, Yuehua Ni

“…In the meantime, compared with the placebo group, fluvoxamine group did not show any higher risk of AEs (P = 0.13 and 0.91, respectively) in safety outcomes analysis. The subgroup analysis showed that fluvoxamine treatment performed more than 200 mg daily appears to be more effective than those performed less than 200 mg daily in reducing clinical deterioration and hospitalization risks, while not exhibiting higher AE and SAE risks than placebo group.…”
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The Impact of Intracoronary Imaging on PCI Outcomes in Cases Utilising Rotational Atherectomy: An Analysis of 8,417 Rotational Atherectomy Cases from the British Cardiovascular Int... by Majd B. Protty, Sean Gallagher, Andrew S. P. Sharp, Vasim Farooq, Mohaned Egred, Peter O’Kane, Peter Ludman, Mamas A Mamas, Tim Kinnaird

“…Adjusted rates of in-hospital major adverse cardiac/cerebrovascular events (IH-MACCE), its individual components (death, peri-procedural MI, stroke, and major bleed), or 12-month mortality were not significantly altered by the use of imaging in RA-PCI. However, subgroup analysis demonstrated a signal towards reduction in 12-month mortality in uLMS RA-PCI cases utilising intracoronary imaging (OR 0.67, 95% CI 0.44–1.03). …”
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Anthropometric and Biochemical Profile of Children and Adolescents with Chronic Kidney Disease in a Predialysis Pediatric Interdisciplinary Program by Vanessa R. Silva, Cristina B. Soares, Juliana O. Magalhães, Isabella Peixoto de Barcelos, Debora C. Cerqueira, Ana Cristina Simões e Silva, Eduardo A. Oliveira

“…Analyses stratified according to clinical variables of interest showed a significant improvement in body mass index (BMI) Z score, especially in the subgroup of children admitted under two years of age. …”
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Psychometric validation of the continuum beliefs of mental illness scale (CB-MIS) and its associations with stigma by Lina-Jolien Peter, Thomas McLaren, Samuel Tomczyk, Holger Muehlan, Silke Schmidt, Georg Schomerus

“…Future studies should conduct subgroup-specific investigations regarding sociodemographic and illness variables, and could apply this measure to anti-stigma interventions. …”
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The impact of depression and anxiety disorders on postoperative outcomes for patients having total hip or knee arthroplasty: Protocol of a meta-analytic study from cohort studies. by Liang Lin, Qing Zhang, Min Xu, Zhihong Xiao, Guosong Xu, Zubing Mei

“…Sources of heterogeneity will be explored via subgroup analyses or meta-regression if possible. Potential publication bias will be visually assessed using funnel plots and statistically tested using Egger's test. …”
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Outcomes of Pembrolizumab plus chemotherapy for patients with metastatic non-squamous NSCLC: Real-world evidence by Irina Surovtsova, Felix J. F. Herth, Daria B. Kokh, Philipp Morakis

“…This study aims to evaluate immunochemotherapy outcomes in a real-world setting, including subgroups underrepresented in the KEYNOTE-189 trial.Methods Patients diagnosed with non-squamous mNSCLC 2011-2022 and recorded in Cancer Registry Database of the German Federal State Baden-Württemberg (BWCR), were analysed. …”
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Large-bore aspiration thrombectomy for the treatment of pulmonary embolism in octogenarians by Reid Masterson, Travis Pebror, Andrew Gauger, Adam William Schmitz, Sabah David Butty

“…This included the octogenarian subgroup from a recently published retrospective analysis assessing all PE patients treated with LBAT at our center between September 2019 and January 2023. …”
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