Effects of traditional Chinese exercises on brain-derived neurotrophic factor in middle-aged and older adults: A systematic review and meta-analysis of randomized controlled trials by Jianyu Gan, Jiya He, Kaixiang Zhou, Zhangyuting Shang, Gengxin Dong, Dapeng Bao, Junhong Zhou

“…Recent studies suggested that Traditional Chinese exercises (TCEs) may be a promising strategy to improve the BDNF levels of these populations, while the effectiveness has yet to be definitively confirmed due to the variances in the study designs and observations. Therefore, this systematic review and meta-analysis aimed to examine the effects of TCEs intervention on BDNF in middle-aged and older adults. …”
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Development of the Dutch translational knowledge agenda for inherited metabolic diseases by I. J. Hieltjes, J. H. van derLee, M. C. Groenendijk, G. vanHaaften, P. M. vanHasselt, R. J. Lunsing, G. J. J. vanProoijen, E. M. deRuiter, F. J. vanSpronsen, N. M. Verhoeven‐Duif, A. deVreugd, M. Wagenmakers, H. Zweers, H. Dekker, H. R. Waterham, C. D. vanKarnebeek, R. J. A. Wanders, R. A. Wevers

“…The resulting top 10 research questions cover multiple themes, i.e. prediction of disease progression, development of novel tools, mechanistic insights, improved diagnostics, therapeutic integration of multi‐omics techniques, assessment of impact on daily life, expanding treatment avenues, optimal study designs, effect of lifestyle interventions, and data utilization using FAIR principles. …”
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Barriers and enablers to young people accessing sexual and reproductive health services in Pacific Island Countries and Territories: A scoping review. by Maggie Ikinue Baigry, Robin Ray, Daniel Lindsay, Angela Kelly-Hanku, Michelle Redman-MacLaren

“…We assessed the quality of each study according to the study designs, methods of data collection, data analysis and ethical considerations. …”
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The effectiveness of dyadic interventions for health outcomes of prostate cancer patients and informal caregivers: a systematic review and meta-analysis by Yuan Xiao, Jiao Sun, Min Liu, Haifeng Wang, Jingjing Guan

“…However, given features such as research quality and sample size, further randomized controlled trials with excellent study designs are needed in the future to evaluate and validate the efficacy of dyadic care treatments for patients with prostate cancer. …”
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Remote work transition amidst COVID-19: Impacts on presenteeism, absenteeism, and worker well-being-A scoping review. by Behdin Nowrouzi-Kia, Alexia M Haritos, Bao-Zhu Stephanie Long, Chantal Atikian, Luke A Fiorini, Basem Gohar, Aaron Howe, Yiyan Li, Ali Bani-Fatemi

“…., working age), engaged in full or part-time work, and the employees shifted from in-person to remote work due to the COVID-19 pandemic. All study designs, geographical areas, and papers written post-onset of the COVID-19 pandemic were included; however, systematic reviews were excluded. …”
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Making the most of existing research: an evidence gap map of the effects of food systems interventions in low-income and middle-income countries by Birte Snilstveit, Ingunn Gilje Storhaug, Charlotte Lane, Nick Moore, Mark Engelbert, Thalia Morrow Sparling, Amber Franich, Heike Rolker

“…Objective Identify and describe the available evidence on the effects food systems interventions on food security and nutrition outcomes in low-income and middle-income countries.Methods An adapted version of the high-level panel of experts food systems framework defined the interventions and outcomes included studies. Included study designs were experimental and quasi-experimental quantitative impact evaluations and systematic reviews. …”
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Learning by making – student-made models and creative projects for medical education: systematic review with qualitative synthesis by Tan Yong Yi, Panwar Shreyans, Ranganath Vallabhajosyula

“…A narrative synthesis was conducted to summarize study designs and outcome measures. Content analysis was conducted to generate codes and themes. …”
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Efficacy of Health Literacy Interventions for Caregivers of Individuals with Neurodevelopmental and Chronic Conditions: A Rapid Review by Thom Nevill, Jessica Keeley, Susan Hunt, Rachel Skoss, Olivia Lindly, Jenny Downs, Amanda Marie Blackmore

“…All original intervention study designs were eligible, as were systematic reviews. …”
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Interventions to improve media coverage of medical research: a codesigned feasibility and acceptability study with Australian journalists by Brooke Nickel, Ray Moynihan, Alexandra Barratt, Kirsten J McCaffery, Loai Albarqouni, Tessa Copp, Thomas Dakin, Liam Mannix

“…This study aimed to codesign and assess the feasibility of a multicomponent training intervention for journalists in Australia.Design A small pragmatic feasibility study using a pre- and postdesign.Setting 90 min online workshop.Participants Eight journalists currently working in Australia, recruited through the study’s journalist advisor and existing contacts of the researchers.Intervention The training intervention covered a range of topics, including study designs, conflicts of interest, misleading medical statistics, population screening and overdiagnosis. …”
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Favorable Nonclinical Safety Profile of RSVpreF Bivalent Vaccine in Rats and Rabbits by Jun Zhou, Christopher J. Bowman, Vicki R. Markiewicz, Balasubramanian Manickam, Emily Gomme, Rani S. Sellers, Cynthia M. Rohde

“…<b>Methods</b>: Nonclinical safety studies, including a repeat-dose toxicity (RDT) study in rats and a combined developmental and reproductive toxicity (DART) study in rabbits, were conducted to support early clinical development. Study designs and parameters evaluated in these studies were consistent with principles and practices as outlined in relevant regulatory guidelines. …”
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Challenges and possibilities when doing research on active school travel interventions in a school setting - a non-randomized pilot study assessing feasibility of an evaluation des... by Mathias Andersson, Elena Tseli, Anna-Karin Lindqvist, Stina Rutberg, Annie Palstam

“…Evaluation of the effectiveness of interventions requires suitable study designs and feasible quantitative evaluations relating to the school setting. …”
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Comparative efficacy of acupuncture therapies in premature ovarian failure: A systematic review and network meta-analysis by Yonghang Yi, Fengjun Ma, Yang Jiao, Rongqi Zhang, Yunhao Yi, Yuxia Ma

“…This study aimed to systematically review the literature and conduct a network meta-analysis (NMA) to compare the efficacy of different acupuncture and related therapies and identify methodologic weaknesses in previous studies. Design: We systematically searched six databases from their inception to April 2024 for randomized controlled trials (RCTs) of acupuncture therapies for POF. …”
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A preliminary simulator study on exploring responses of drivers to driving system reminders on four stimuli in vehicles by Zhao Zou, Fady Alnajjar, Michael Lwin, Luqman Ali, Hamad Al Jassmi, Omar Mubin, Muhammad Swavaf

“…Therefore, there is an increasing demand for vehicles integrated with assistive driving systems. This pilot study designed to explore which type of driving system reminders, namely Text display, Image display, alarm notification, or humanoid voice command, provokes stronger preferences and higher rates of cooperation from drivers. …”
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Minimal clinical data sets for spine-related musculoskeletal disorders in primary care and outpatient settings: a scoping review protocol by Pierre Côté, Andrea C Tricco, Cesar A Hincapié, Léonie Hofstetter, Jérémie Mikhail, Isabelle Pagé

“…Quantitative and qualitative study designs will be eligible, including consensus-based studies, interventional, observational, feasibility and linguistic validation studies. …”
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Dynamic responses characteristics of bedrock and overburden layer slope with anchored frame piles based on shaking table test by Lei Wang, Qianhui Pu, Guangpeng Chen, Jing Lian, Changwei Yang, Mingming Dai

“…Abstract To adapt to higher and steeper slope environments, this paper proposes a new type of support structure called an anchored frame pile. The study designed and conducted a series of shaking table tests with three-way loading. …”
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Aetiological research on the health of migrants living in Germany: a systematic literature review by Oliver Razum, Florian Fischer, Ina Danquah, Claudia Hövener, Patricia Nayna Schwerdtle, Tracy Bonsu Osei, Isabel Mank, Raissa Sorgho

“…The main objective was to systematically identify, evaluate and synthesise population-based studies that investigated exposure–outcome relationships among migrant groups in Germany.Methods In November 2019, we searched PubMed and LIVIVO, and updated this search in November 2020, to identify peer-reviewed publications that fulfilled our eligibility criteria: English or German language; study on disease aetiology among major migrant groups in Germany, according to the latest microcensus; publication date from inception to 01 November 2020 and observational or experimental study designs. For quality appraisal, we used the Critical Appraisal Skills Programme checklists. …”
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Prevalence and determinants of persistent symptoms after infection with SARS-CoV-2: protocol for an observational cohort study (LongCOVID-study) by Lotte Haverman, Eelco Franz, Ka Yin Leung, Albert Jan Van Hoek, Hans Knoop, Cees C van den Wijngaard, Elizabeth N Mutubuki, Tessa van der Maaden, Albert Wong, Anna D Tulen, Siméon de Bruijn

“…Estimates on prevalence vary due to differences in study designs, populations, heterogeneity of symptoms and the way symptoms are measured. …”
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Personalised Lung Cancer Screening (PLuS) study to assess the importance of coexisting chronic conditions to clinical practice and policy: protocol for a multicentre observational... by Yi Guo, Dongyu Zhang, Rafael Meza, Jihyoun Jeon, Dejana Braithwaite, Gerard A Silvestri, Michael K Gould, Jiang Bian, Bruno Hochhegger, Shama D Karanth, Christopher G Slatore, Martin Tammemagi, Mattthew Schabath, Meghann Wheeler, Frederic J Kaye

“…The principal goal of the PLuS study is to characterise the comorbidity burden of individuals undergoing LCS and quantify the benefits and harms of LCS to enable informed decision-making.Methods and analysis PLuS is a multicentre observational study designed to assemble an LCS cohort from the electronic health records of ~40 000 individuals undergoing annual LCS with LDCT from 2016 to 2022. …”
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Efforts to strengthen anatomic pathology diagnostic services for cancer in sub-Saharan Africa: a scoping review protocol by Katherine Van Loon, Elia John Mmbaga, Marcia Edelweiss, Dianna L. Ng, Asteria Herman Kimambo, Edda Vuhahula, Beatrice Paul Mushi, Omolade Adegoke, Johanna Goldberg, Pendo M. Ibrahim, Zainab Illonga, Julia Jackman, Luisa Jamisse

“…This review will consider scientific literature from published primary studies as well as scoping and systematic reviews related to capacity-building efforts to strengthen anatomic pathology services in any sub-Saharan African country. All study designs will be considered, including quantitative, qualitative and/or mixed-methods studies.Ethics and dissemination Ethical approval is not required for this study. …”
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PretoxTM: a text mining system for extracting treatment-related findings from preclinical toxicology reports by Javier Corvi, Nicolás Díaz-Roussel, José M. Fernández, Francesco Ronzano, Emilio Centeno, Pablo Accuosto, Celine Ibrahim, Shoji Asakura, Frank Bringezu, Mirjam Fröhlicher, Annika Kreuchwig, Yoko Nogami, Jeong Rih, Raul Rodriguez-Esteban, Nicolas Sajot, Joerg Wichard, Heng-Yi Michael Wu, Philip Drew, Thomas Steger-Hartmann, Alfonso Valencia, Laura I. Furlong, Salvador Capella-Gutierrez

“…Much of this information is contained in toxicology reports, which summarise the results of animal studies designed to analyse the effects of the tested compound, including unintended pharmacological and toxic effects, known as treatment-related findings. …”
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