Synergistic effects of recombinant expressed Fowlicidin and Thymosin α1 hybrid peptides in modulating inflammation and infection in avian macrophages by Baseer Ahmad, Baseer Ahmad, Zaheer Abbas, Wei Xubiao, Kashif Hussain, Atif Rehman, Si Dayong, Asghar Abbas, Christina Hölzel, Zhang Rijun

“…Furthermore, physiochemical and structural analysis revealed an amphipathic helical configuration that enhances bioactivity. …”
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The Striated Solar Photosphere Observed at Resolution by David Kuridze, Friedrich Wöger, Han Uitenbroek, Matthias Rempel, Alexandra Tritschler, Thomas Rimmele, Catherine Fischer, Oskar Steiner

“…Both observed and synthetic images reveal photospheric striae with widths of approximately 20−50 km, suggesting that at least 4 m class solar telescopes are necessary to resolve this ultrafine structure. Analysis of the numerical simulations confirms that the striation observed in the filtergrams is associated with spatial variations in photospheric magnetic flux concentrations, which cause shifts in the geometrical height where the emergent intensity forms. …”
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Ethylene/Styrene Copolymerization by (Me₃SiC₅H₄)TiCl₂(O-2,6-<i>ⁱ</i>Pr₂-4-RC₆H₂) (R = H, SiE... by Tiantian Huang, Taiga Fujioka, Daisuke Shimoyama, Kotohiro Nomura

“…The synthesis and structural analysis of (Me₃SiC₅H₄)TiCl₂(OAr) [OAr = O-2,6-<i>ⁱ</i>Pr₂-4-RC₆H₂; R = H, SiEt₃] revealed that it exhibits higher catalytic activities than (<i>^t</i>BuC₅H₄)TiCl₂(OAr), Cp*TiCl₂(OAr), with efficient comonomer incorporation in ethylene/styrene copolymerization in the presence of a methylaluminoxane (MAO) cocatalyst. …”
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Strength characteristics in saturation process and rainfall-induced landslide failure mechanism of granite residual soil by Bing Lan, Bangzhong Jia, Yiying Wu, Yiying Wu, Xiaoyu Yi, Wenkai Feng, Yihe Li

“…This study investigates the hydro-mechanical behavior of Minqing County (Fujian Province) granite residual soils through direct shear tests and novel meso-structural analysis using scanning electron microscopy (SEM). …”
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Identification and characterization of a novel human adenovirus type HAdV-D116 by Menglan Zhou, Menglan Zhou, Wenjing Chen, Dong Zhang, Dong Zhang, Shicheng Ma, Mange Liu, Lili Ren, Jiayu Guo, Jiayu Guo, Yi Gao, Yi Gao, Minya Lu, Minya Lu, Huiting Su, Huiting Su, Ying Zhao, Ying Zhao, Yingchun Xu, Yingchun Xu, Qiwen Yang, Qiwen Yang, Qiwen Yang

“…Recombination analysis suggested that HAdV-D116 is a recombinant strain derived from HAdV-D33, HAdV-D28, and HAdV-D71. Structural analysis of the fiber-knob domain indicated that HAdV-D116 likely uses sialic acid as a receptor.DiscussionThe unique genomic features of HAdV-D116, combined with the patient’s immunodeficiency, are proposed to contribute to its possible CNS infectivity. …”
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Improvement of Catalytic Activity and Thermostability of Alginate Lyase VxAly7B-CM via Rational Computational Design Strategies by Xin Ma, Ke Zhu, Kaiyang Wang, Wenhui Liao, Xiaohan Yang, Wengong Yu, Weishan Wang, Feng Han

“…Moreover, its half-life at 50 °C was 38.4 h, which is 7.0 times that of the wild-type enzyme. Protein structural analysis and molecular dynamics simulations suggested that the enhanced catalytic performance and thermostability of the E188N/S204G mutant may be attributed to optimized surface charge distribution, strengthened hydrophobic interactions, and increased tertiary structure stability. …”
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Genetic Diversity Analysis of <i>Capsicum frutescens</i> Based on Simplified Genome Sequencing Technology by Lidong Wu, Yinhui Qiu, Shuting Lin, Rui Zhang, Lihao Wang, Yongqing Li, Yacong Cao

“…Through population genetic structure analysis, the population structure and phylogenetic tree of 65 <i>C. frutescens</i> germplasms were constructed. …”
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Elimination of Ethanol for the Production of Fucoidans from Brown Seaweeds: Characterization and Bioactivities by Periaswamy Sivagnanam Saravana, Shanmugapriya Karuppusamy, Dilip K. Rai, Janith Wanigasekara, James Curtin, Brijesh K. Tiwari

“…This paper provides research findings on green extraction methods, structural analysis of fucoidan, and its associated bioactivities. …”
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Enhancing Sialidase Production from the <i>Oerskovia paurometabola</i> O129 Strain by the Optimization of Fermentation Parameters and the Addition of Stimulative Compounds by Yana Gocheva, Ekaterina Krumova, Irina Lazarkevich, Rumyana Eneva, Stephan Engibarov

“…Sialidases are gradually entering various areas of human practice—in medicine and pharmacy, as antiviral, antitumor, diagnostic, and vaccine preparations; for the chemoenzymatic synthesis of regioselective sialoglycoconjugates; and for the structural analysis of sialoglycoproteins. Optimizing the synthesis conditions of these commercially important enzymes would be beneficial for enhancing their production and expanding potential applications. …”
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Influence of Overlying Caprock on Coalbed Methane Migration in the Xutuan Coal Mine, Huaibei Coalfield, China: A Conceptional Analysis on Caprock Sealability by Kaizhong Zhang, Qingquan Liu, Kan Jin, Liang Wang, Yuanping Cheng, Qingyi Tu

“…Results indicate that the basic properties of coal were not significantly changed whereas the effect of coalbed gas escape was promoted in the presence of Redbed and loose bed. The pore structure analysis shows that Redbed has well-developed pore connectivity than coal-bearing strata (main components are sandstone, siltstone, and mudstone). …”
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Stochastic demethylation and redundant epigenetic suppressive mechanisms generate highly heterogeneous responses to pharmacological DNA methyltransferase inhibition by Mie K. Jakobsen, Sofie Traynor, Aaraby Y. Nielsen, Christina Dahl, Mette Staehr, Simon T. Jakobsen, Maria S. Madsen, Rasmus Siersbaek, Mikkel G. Terp, Josefine B. Jensen, Christina B. Pedersen, Anup Shrestha, Jonathan R. Brewer, Pascal H. G. Duijf, Odd L. Gammelgaard, Henrik J. Ditzel, Alexei F. Kirkin, Per Guldberg, Morten F. Gjerstorff

“…Mechanistic insights were further gained through DNA methylation profiling and chromatin structure analysis. Results We show that breast cancer tumors and cell cultures exhibit a highly heterogenous response to DNA methyltransferase inhibitors, persisting even under high drug concentrations and efficient DNA methyltransferase depletion. …”
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Humidity sensing enhancement through n-/p-type CdO-CrO heterostructures for eco-friendly monitoring systems by Adil Rauf, Rizwan Akram, Ayesha Masood, Zahid Imran, Safia Hassan, Shumaila Karamat

“…In this study, CrO was prepared via sol-gel route, CdO metal oxide prepared via co-precipitation method, and finally the composite of CdO-CrO was achieved by mixing both the materials in mortar and pestle. The structural analysis was done for all the three samples using X-ray Diffraction (XRD) which confirms the successful formation of CdO and CrO and CdO-CrO composite material. …”
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Metagenomics combined with activity-based proteomics point to gut bacterial enzymes that reactivate mycophenolate by Joshua B. Simpson, Josh J. Sekela, Amanda L. Graboski, Valentina B. Borlandelli, Marissa M. Bivins, Natalie K. Barker, Alicia A. Sorgen, Angie L. Mordant, Rebecca L. Johnson, Aadra P. Bhatt, Anthony A. Fodor, Laura E. Herring, Hermen Overkleeft, John R. Lee, Matthew. R. Redinbo

“…We found that the presence of GUS enzymes that bind the flavin mononucleotide (FMN) is significantly correlated with efficient MPA reactivation. Furthermore, structural analysis identified motifs unique to these FMN-binding GUS enzymes that provide molecular support for their ability to process this drug glucuronide. …”
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Green Synthesis, Characterization, and Biological Activity of 4-Aminoquinoline Derivatives: Exploring Antibacterial Efficacy, MRSA Inhibition, and PBP2a Docking Insights by Lo’ay A. Al-Momani, Ula A. Abu Shawar, Ayman H. Abu Sarhan, Rand Shahin, Panayiotis A. Koutentis, Mohammad K. Abu-Sini, Nada J. Mohammad

“…Heating the reactions to 90–150 °C for 90–120 minutes obtained products with up to 95% yields. Structural analysis and characterization were achieved using FT-IR, ¹H- and ¹³C-NMR spectroscopy and HR-MS. …”
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Structural dynamics of RAF1-HSP90-CDC37 and HSP90 complexes reveal asymmetric client interactions and key structural elements by Lorenzo I. Finci, Mayukh Chakrabarti, Gulcin Gulten, Joseph Finney, Carissa Grose, Tara Fox, Renbin Yang, Dwight V. Nissley, Frank McCormick, Dominic Esposito, Trent E. Balius, Dhirendra K. Simanshu

“…Employing 1 μs atomistic simulations, energetic decomposition, and comparative structural analysis, we elucidate the dynamics and interactions within these complexes. …”
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Evaluation of Antigenicity of Components of Tracheal Allotransplant and Effect of Immunosuppressant Regime in a Rodent Model by Dimpy Sharma, Subramania Iyer, Sobha Subramaniam, Janarthanan Ramu, Mohit Sharma, Ajit Nambiar, AKK Unni, Sivanarayanan S.

“…The antigenicity of different layers of trachea and the effect of various decellularization methods were studied within three time frames, that is, day 3, 9, and 15. Result On structural analysis, the day 3 and day 15 samples showed no meaningful comparison could be made, due to extensive neutrophil infiltration in all three layers. …”
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Interfacial subregions of SARS-CoV-2 spike RBD to hACE2 affect intermolecular affinity by their distinct roles played in association and dissociation kinetics by Xiangwu Tang, Jingxian Chen, Lu Zhang, Tao Liu, Min Ding, Yun-Wen Zheng, Yinghui Zhang

“…The kinetic data and structural analysis of local mutations’ impact on spike RBD’s binding and thermal stability provide a new perspective in evaluating SARS-CoV-2 evolution and other sarbecoviruses’ evolvable binding to hACE2. …”
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Systematic free energy insights into the enhanced dispersibility of myofibrillar protein in low-salt solutions through ultrasound-assisted enzymatic deamidation by Yating Liu, Zongyun Yang, Zhen Li, Juan Shen, Xia Wang, Ru Li, Ye Tao, Xinglian Xu, Peng Wang

“…Although secondary structure analysis showed that MP-PG and MP-U-PG had an increased α-helix ratio and a decreased β-sheet ratio, ultrasonic treatment had a significantly influence on the MD results. …”
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Xyloglucan endotransglucosylase/hydrolase 25 positively regulates the lead tolerance in Raphanus sativus by Tong Han, Yongmei Cui, Yang Jing, Meiying Liu, Xuanchao Chen, Yinghui Song, Xinping Gu, Jiahao Wang, Long Wang, Long Wang

“…In this study, 28 XTH genes were identified in R. sativus. Gene structure analysis revealed the presence of eight conserved motifs, along with variations in exon-intron organization and chromosomal distribution across all chromosomes. …”
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Isolation and identification of serotonin compound from banana hump: a reproductive stimulant for tiger shrimp Penaeus monodon broodstock enhancement by Andi Parenrengi, Emma Suryati, Rachman Syah, Andi Tenriulo, Samuel Lante, Elmi Nurhaidah Zainuddin, Ratu Siti Aliah, Nuril Farizah, Agus Nawang, Sulaeman Sulaeman, Makmur Makmur, Rosmiati Rosmiati, Gunarto Gunarto, Herlinah Herlinah

“…Results Based on the chemical structure analysis, the stimulant component of the banana hump was identified as a serotonin compound (5-hydroxytryptamine) at a concentration of 0.7% of dry weight. …”
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