Molecular epidemiology and pathogenicity of Wesselsbron virus circulating in Africa by Martin Faye, Nicholas Di Paola, Moussa Dia, Amadou Alpha Sall, Ousmane Faye

“…Herein, we investigated the molecular epidemiology of Wesselsbron virus in Africa using whole genome sequencing and structural analysis, and assessed its pathogenicity and tropism through in vivo experiments. …”
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Assay development and screening of inhibitors targeting the SARS-CoV-2 2′-O-methyltransferase NSP16 by Mengtong Cao, Carl W. Trieshmann, Subodh Kumar Samrat, Hongmin Li, Yifei Wu, Steven P. Maher, Angela A. Bae, Zhong-Ru Xie, Robert J. Hogan, Y. George Zheng

“…We identified potential hits that inhibit the NSP16 activity with cellular efficacy. Together with structural analysis and chemotype categorization, this study lays the groundwork for novel antiviral therapeutics development against SARS-CoV-2 and related coronaviruses.…”
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Structural insights into terminal arabinosylation of mycobacterial cell wall arabinan by Yaqi Liu, Chelsea M. Brown, Satchal Erramilli, Yi-Chia Su, Shih-Yun Guu, Po-Sen Tseng, Yu-Jen Wang, Nam Ha Duong, Piotr Tokarz, Brian Kloss, Cheng-Ruei Han, Hung-Yu Chen, José Rodrigues, Kay-Hooi Khoo, Margarida Archer, Anthony A. Kossiakoff, Todd L. Lowary, Phillip J. Stansfeld, Rie Nygaard, Filippo Mancia

“…Through an integrated approach combining structural analysis, biochemical assays, and molecular dynamics simulations, we delineate the molecular basis of AftB’s reaction mechanism and propose a model for its catalytic function.…”
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Electronic structure and adsorption stability of ferrocene on Au (111) and Ag (111) surfaces by Shuhao Li, Chunqing Li, Feng Wang

“…Parallel configurations are less stable, with S-Fc failing to adsorb stably. Electronic structure analysis confirmed the presence of region-specific charge transfer electron circuits in the vertical configuration, which in turn enhanced the adsorption strength on the Au(111) surface. …”
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Structural reliability of hollow core slabs considering compressive membrane action by Thomas Thienpont, Ruben Van Coile, Wouter De Corte, Robby Caspeele

“…In parallel with these tests, a numerical finite element model has been developed in order to perform a more detailed structural analysis of this phenomenon, and to study the influence of various input parameters. …”
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Genome-Wide Association Study and Genomic Prediction of Essential Agronomic Traits in Diversity Panel of Soybean Varieties by Qianli Dong, Yuting Cheng, Yiyang Li, Yan Tong, Dazhuang Liu, Jiaxin Yu, Na Zhao, Bao Liu, Xiaoyang Ding, Chunming Xu

“…The population structure analysis, based on genotyping-by-sequencing (GBS) data, revealed seven subpopulations within the panel and significant gene flows among these subpopulations. …”
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Evaluation and prediction of superhydrophobic surface durability using rolling wear tests and finite element analysis by Kyeongryeol Park, Hyunjong Kim, Kihwan Kim, Changwoo Lee, Amir Asadi, Ho Jun Kim, Kyungjun Lee

“…The study demonstrates that durability predictions based on surface deformation and structural analysis can enhance our understanding of wear mechanisms and improve the practical application of superhydrophobic surfaces in various industries. …”
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Purification and Molecular Characterization of a Mammalian Neurotoxin as a Pharmaceutical Tool from the Venom of Iranian Scorpion Androctonus crassicauda by Hadi Rabiei, Abbas Zare Mirakabadi, Bita Mohtat, Behrooz Mirza

“…Results: The primary structure analysis exhibits a neurotoxin named AnCra2 with 7302.24 Da molecular weight and 64 amino acid residues that cause paralysis and lead to death in NIH mice. …”
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Structural basis for human OGG1 processing 8-oxodGuo within nucleosome core particles by Mengtian Ren, Fabian Gut, Yilan Fan, Jingke Ma, Xiajing Shan, Aysenur Yikilmazsoy, Mariia Likhodeeva, Karl-Peter Hopfner, Chuanzheng Zhou

“…To reveal the underlying molecular mechanism of this phenomenon, we determine the 3.1 Å cryo-EM structure of human 8-oxoguanine-DNA glycosylase 1 (hOGG1) bound to a nucleosome core particle (NCP) containing a common oxidative base lesion, 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodGuo). Our structural analysis shows that hOGG1 can recognize and flip 8-oxodGuo even within NCPs; however, the interaction between 8-oxodGuo and hOGG1 in a NCP context is weaker than in free DNA due to competition for nucleosomal DNA by the histones. …”
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Hydrogen and syngas production from gasification of lignocellulosic biomass in supercritical water media by Farid Safari, Ahmad Tavasoli, Abtin Ataei, Jun-Ki Choi

“…Taking into account the structural analysis, it was recognized that feedstocks with higher cellulose and hemicellulose and lower lignin contents were better gasified due to their easier hydrolysis and higher solubility in water.…”
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USP7 V517F mutation as a mechanism of inhibitor resistance by Yu-Ling Miao, Fengying Fan, Yong-Jun Cheng, Li Jia, Shan-Shan Song, Xia-Juan Huan, Xu-Bin Bao, Jian Ding, Xuekui Yu, Jin-Xue He

“…We discovered a key treatment-emergent heterozygous mutation (V517F) in USP7 in the binding pocket of compounds as the primary cause of resistance to the USP7 inhibitor USP7-797. Our structural analysis, supported by AlphaFold2 predictions, indicates that the V517F mutation altered the conformation of the compound binding pocket, causing steric hindrance and reducing the affinity between USP7 and its inhibitors. …”
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Genetic Diversity and Construction of Salt-Tolerant Core Germplasm in Maize (<i>Zea mays</i> L.) Based on Phenotypic Traits and SNP Markers by Yongfeng Song, Jiahao Wang, Yingwen Ma, Jiaxin Wang, Liangliang Bao, Dequan Sun, Hong Lin, Jinsheng Fan, Yu Zhou, Xing Zeng, Zhenhua Wang, Lin Zhang, Chunxiang Li, Hong Di

“…Whole-genome genotyping was conducted using the Maize6H-60K liquid phase chip. Population structure analysis, principal component analysis, and cluster analysis divided the 588 accessions into six subgroups. …”
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Micrometer long bimetallic Nickel-cobalt schiff base MOF as supercapacitor electrodes by S. Parveen, A. Shanmugapriya, B. Saravanakumar, J.Johnson William, N. Chithra

“…Nickel and Nickel-cobalt [Ni1/3Co2/3(HL)2].3H2O Schiff base complexes were synthesized from 2-(methoxycarbonyl-hydrazono)-pentanedioic acid, H2L ligand with metal salts. The structural analysis reveals that the prepared samples were endowed with well crystalline nature. …”
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A new ALK inhibitor overcomes resistance to first‐ and second‐generation inhibitors in NSCLC by Yue Lu, Zhenzhen Fan, Su‐Jie Zhu, Xiaoxing Huang, Zhongji Zhuang, Yunzhan Li, Zhou Deng, Lei Gao, Xuehui Hong, Ting Zhang, Li Li, Xihuan Sun, Wei Huang, Jingfang Zhang, Yan Liu, Baoding Zhang, Jie Jiang, Fu Gui, Zheng Wang, Qiyuan Li, Siyang Song, Xin Huang, Qiao Wu, Lanfen Chen, Dawang Zhou, Jianming Zhang, Cai‐Hong Yun, Liang Chen, Xianming Deng

“…XMU‐MP‐5 blocks ALK signaling pathways and inhibits the proliferation of cells harboring either wild‐type or mutant EML4‐ALK in vitro and suppresses tumor growth in xenograft mouse models in vivo. Structural analysis provides insights into the mode of action of XMU‐MP‐5. …”
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Automated system for high-throughput process-structure-property dataset generation of structural materials: A γ/γ′ superalloy case study by Thomas Hoefler, Ayako Ikeda, Toshio Osada, Toru Hara, Kyoko Kawagishi, Takahito Ohmura

“…By aging the sample in a temperature gradient, a wide range of aging process temperatures is mapped over the sample length. Structure analysis consists of fully automated, nanometer-resolution FE-SEM scanning, with precipitate fraction, size and shape distributions determined by automatic image analysis using the Python programming language. …”
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Novel FRET‐Based Biosensors for Real‐Time Monitoring of Estrogen Receptor Dimerization and Translocation Dynamics in Living Cells by Kiseok Han, Jung‐Soo Suh, Gyuho Choi, Yoon‐Kwan Jang, Sanghyun Ahn, Yerim Lee, Tae‐Jin Kim

“…This approach involves comprehensive structural analysis, linker comparison, and the selection of optimal fluorescent protein pairs, resulting in three distinct biosensors capable of detecting all ER homo‐ and hetero‐dimerizations within the nucleus. …”
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Influence of Geometrical Design on Defect Formation of Commercial Al-Si-Cu-Mg Alloy Fabricated by High-Pressure Diecasting: Structural Observation and Simulation Validation by Warda Bahanan, Siti Fatimah, Dong-Ju Kim, I Putu Widiantara, Jee-Hyun Kang, Young Gun Ko

“…Because the associated work primarily relies on technical experience, it is necessary to perform the structural analysis of the HPDed component in comparison with simulation-based findings that forecast flow behavior, hence reducing trial and error for optimization. …”
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Structure and function of human XPR1 in phosphate export by Long Chen, Jin He, Mingxing Wang, Ji She

“…In addition, our structural analysis reveals a new conformational state of HsXPR1 in which the cytoplasmic SPX domains form a V-shaped structure. …”
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Genomic epidemiology and phenotypic characterization of Staphylococcus aureus isolated from atopic dermatitis patients in South China by Chao Yang, Xiaowei Chen, Min Li, Wenchang Yuan, Shunguang Li, Dexing Han, Junhui Feng, Haimin Luo, Minling Zheng, Jiaqi Liang, Cha Chen, Pinghua Qu, Song Li

“…Phylogenetic and population structure analysis revealed that 579 strains of global AD were classified into 15 sequence clusters (SCs), with SC5, SC2, and SC7 dominating. …”
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The Effect of Particle Size on the Interpretation of Pore Structure of Shale by N2 Adsorption by Chengfu Lyu, Xinmao Zhou, Xuesong Lu, Ying Zhang, Chao Li, Qianshan Zhou, Zhaotong Sun, Guojun Chen

“…Furthermore, to interpret the data, several attributes such as the pore volume, surface area, fractal dimension (from the fractal analysis), and heterogeneity index (from the multifractal analysis), are studied and compared between the samples and particle size intervals to provide us with the effect that particle size could have on the pore structure analysis. The results showed that as the particle size varies, the pore structures of the shale samples could get affected. …”
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