Truncating the C terminus of formate dehydrogenase leads to improved preference to nicotinamide cytosine dinucleotide by Xiaojia Guo, Xueying Wang, Yinghan Hu, Lingyun Zhang, Zongbao K. Zhao

“…Sequence comparison analysis showed that C-terminal residues were barely conservative among different FDHs. pseFDH and mutants with their C termini truncated were constructed, and the resulted variants showed improved preference to NCD mainly because NAD-dependent activity dropped more substantially. Further structure analysis showed that these pseFDH variants had their cofactor binding domains reconstructed to favor molecular interactions with NCD. …”
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A humanized nanobody phage display library yields potent binders of SARS CoV-2 spike. by Ying Fu, Juliana da Fonseca Rezende E Mello, Bryan D Fleming, Alex Renn, Catherine Z Chen, Xin Hu, Miao Xu, Kirill Gorshkov, Quinlin Hanson, Wei Zheng, Emily M Lee, Lalith Perera, Robert Petrovich, Manisha Pradhan, Richard T Eastman, Zina Itkin, Thomas B Stanley, Allen Hsu, Venkata Dandey, Kedar Sharma, William Gillette, Troy Taylor, Nitya Ramakrishnan, Shelley Perkins, Dominic Esposito, Eunkeu Oh, Kimihiro Susumu, Mason Wolak, Marc Ferrer, Matthew D Hall, Mario J Borgnia, Anton Simeonov

“…Here, we report a rapid and efficient strategy for the development and design of SARS-CoV-2 neutralizing humanized nanobody constructs with sub-nanomolar affinities and nanomolar potencies. CryoEM-based structural analysis of the nanobodies in complex with spike revealed two distinct binding modes. …”
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Exploring the Diversity and Ancestry of Fine-Aroma Cacao from Tumaco, Colombia by Paola Delgadillo-Duran, Jhon A. Berdugo-Cely, Julián Mejía-Salazar, José Ives Pérez-Zúñiga, Roxana Yockteng

“…The analysis yielded 359,950 single nucleotide polymorphisms (SNPs) for Tumaco and identified 38,812 SNPs in common with Colombian National Germplasm Bank genotypes and reference groups. Genetic structure analysis divided Tumaco samples into nine populations, revealing admixtures primarily from the Nacional, Iquitos, Amelonado, and Criollo groups. …”
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A sequence to formula tree model for solving electrical text problems by Yanli Wang, Pengpeng Jian, Haoyu Liu, Ming Yan, Yang Li

“…However, existing solution methods either focus on semantic or structural analysis, and they cannot parse the problem text into a more interpretable form of machine solver. …”
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Exploring the Effects of pH on the Morphology and Optical Characteristics of ZnFe2O4 Nanoparticles by Mahdiyeh Taherkhani, Mohammad Ehsani, Reza Zarei moghadam, Abbas Javadian

“…The synthesis was carried out at various pH levels of 7, 9, and 11, to explore how acidic and basic conditions can influence the characteristics of these nanoparticles. Structural analysis was conducted using X-ray diffraction (XRD), which allowed for a comprehensive understanding of the phase composition and crystallinity of the nanoparticles. …”
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Modeling and Experimentation of the Unidirectional Orthodontic Force of Second Sequential Loop Orthodontic Archwire by Jin-Gang Jiang, Yi-Hao Chen, Lei Wang, Yong-De Zhang, Yi Liu, Wei Qian

“…The different parameters of the second sequential loop are analyzed, and the equivalent beam deflection theory is used to analyze the relationship between orthodontic-force and archwire parameters. Based on the structural analysis of the second sequential loop, the device for measuring orthodontic force has been designed. …”
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Strategic planning of municipalities’ development under post-growth scenarios by Ivan A. Antipin, Elizaveta A. Belousova, Elena A. Shishkina

“…The methods include synthesis, comparative and structural analysis, content analysis and foresight. The evidence base covers municipalities’ strategic planning documents and the composite rating of their socio-economic development in the Sverdlovsk oblast. …”
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Pedagogical analysis of the process of pianism in China by Yawen Hu

“…In the research the following methods were used: a holistic, structural analysis of the associative manifestations of the rich imaginative structure of the music of Chinese composers; analysis of various methods of learning to play the piano. …”
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Genome-wide assessment of population structure and genetic diversity and development of a core germplasm set for sweet potato based on specific length amplified fragment (SLAF) seq... by Wenjin Su, Lianjun Wang, Jian Lei, Shasha Chai, Yi Liu, Yuanyuan Yang, Xinsun Yang, Chunhai Jiao

“…In the present study, the population structure and genetic diversity of 197 sweet potato accessions most of which were from China were assessed using 62,363 SNPs. A model-based structure analysis divided the accessions into three groups: group 1, group 2 and group 3. …”
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Crystal structure of the C-terminal four-helix bundle of the potassium channel KCa3.1. by Tianyang Ji, Senena Corbalán-García, Stevan R Hubbard

“…Near the cytoplasmic C-terminus of KCa3.1 (and KCa2.1-2.3), secondary-structure analysis predicts the presence of a coiled-coil/heptad repeat. …”
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Characteristics of Changes in Residential Building Layouts in Public Rental Housing Complexes in New Towns of Korea by Hyojeong Kim, Byungdeok Roh

“…This study investigates changes in residential building layouts in public rental housing complexes constructed during the 1990s, 2000s, and 2010s to understand how planning practices have evolved over time. Using a structured analysis framework, this research examined layout types (orthogonal, parallel, staggered, and mixed) and key planning elements (density, building height, orientation, and building forms) across 24 complexes. …”
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Characterization of Protein and Peptide Extract from Lamb's Quarters' (Chenopodium Album L.) Seeds: Studying of Composition, Antimicrobial and Analgesic Properties by E. A. Rogozhin, O. V. Kisil, I. V. Cheretaev, S. K. Zavriev

“…In this work a primary structural analysis has been carried out and biological properties of protein-peptide extract from lamb’s quarters ( Chenopodium album L.) were studied. …”
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Enhanced power density in solid oxide fuel cells using nickel-assisted gadolinium-doped ceria anodes. by Nacer Badi, Aashis S Roy, Raghavendra Sagar, Saleh A Alghamdi, Abdulrhman M Alsharari, Alex Ignatiev

“…The synthesized nanocomposites were characterized using Fourier-transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) for structural analysis, and scanning electron microscopy (SEM) for surface morphology assessment. …”
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Key metrics for monitoring performance variability in edge computing applications by Panagiotis Giannakopoulos, Bart van Knippenberg, Kishor Chandra Joshi, Nicola Calabretta, George Exarchakos

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Low-Cyclic Loading Tests of Self-Centering Variable Friction (SCVF) Brace by Qingguang He, Yanxia Bai, Weike Wu, Yongfeng Du

“…The finite element simulation results are essentially consistent with the obtained test results, which is conducive to the use of finite element software for calculation and structural analysis in actual engineering design.…”
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Designing a Psychometric Tool for Measuring Coronavirus Health Literacy of Iranian Adults in Sistan and Baluchestan Province, Iran, in 2020 by Hossein Izadirad, Mohammad Saeed Jadgal, Jamshid Hosseinzehi Zamani

“…Then, the reliability and structural analysis of the tool was evaluated by a descriptive-correlation study conducted on 400 respondents who were selected via sequential non-probability sampling from adults in Sistan and Baluchistan Province, Iran. …”
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Evolution and comparison of the expression of TCP genes in the benincaseae and cucurbiteae tribes by Shuoshuo Wang, Wenli Li, Han Jin

“…Using the melon genome as a reference, an integrated map containing 29 loci across nine chromosomes was constructed, 28 of which were shared by seven Cucurbitaceae species. Gene structure analysis revealed that their function was conserved. …”
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Economic Methods of Managing the Environmental Safety of Cities Abroad: Tax Aspect by S. V. Bogachov, N. I. Malis

“…In the course of the work, general scientific and special methods were used, including content analysis of literary sources, comparison, grouping, analogy, systemic and structural analysis, logical generalization. The results of the study consist in assessing the possibilities and determining the conditions for introducing the best foreign practices in environmental safety management in Russian cities; they can be useful to specialists dealing with both the problems of forming management decisions to stabilize the environmental situation in the city, greening the tax system at the local level, and ensuring the rational use of resources in a mobilization economy through cooperative relations in the processing of industrial and household waste through recycling.…”
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Reliability-Constrained Structural Design Optimization Using Visual Programming in Building Information Modeling (BIM) Projects by Feyzullah Yavan, Reza Maalek

“…The methodology involves multiple stages such as (i) creating parametric trusses employing Visual Programming (VP) software Dynamo (Version: 3.0.4); (ii) performing a First-order Reliability Method (FORM) analysis which includes a Finite Element Method (FEM) analysis as a Limit State Function (LSF); (iii) employing MAs to achieve optimum design variables under uncertain design constraints; (iv) testing the methodology with various real-word examples and scenarios; (v) creating an optimized model on Robot Structural Analysis 2024 (RSA) software in real time in the purpose of further adjustments. …”
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Fluid-Structure Interaction Analysis of Carotid Artery Blood Flow with Machine Learning Algorithm and OpenFOAM by Banu Körbahti, Murad Kucur

“…The research includes the effect of arterial wall deformation by fluid-structure analysis. Pulsatile velocity cycle is trained for 144 patients with different hemodynamic parameters, by machine learning algorithm using blood flow velocity measured from 337 points of the carotid artery. …”
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