Detailed Architecture of the L 98-59 System and Confirmation of a Fifth Planet in the Habitable Zone by Charles Cadieux, Alexandrine L’Heureux, Caroline Piaulet-Ghorayeb, René Doyon, Étienne Artigau, Neil J. Cook, Louis-Philippe Coulombe, Pierre-Alexis Roy, David Lafrenière, Pierrot Lamontagne, Michael Radica, Björn Benneke, Eva-Maria Ahrer, Drew Weisserman, Ryan Cloutier

“…The TTVs of L 98-59 c and d (<3 minutes, P _TTV  = 396 days) constrain the eccentricities of all planets to near-circular orbits ( e  ≲ 0.04). An internal structure analysis of the transiting planets reveals increasing water-mass fractions ( ${f}_{{{\rm{H}}}_{2}{\rm{O}}}$ ) with orbital distance, reaching ${f}_{{{\rm{H}}}_{2}{\rm{O}}}\approx 0.16$ for L 98-59 d. …”
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An immunoinformatics approach in designing high-coverage mRNA multi-epitope vaccine against multivariant SARS-CoV-2 by Ernawati Arifin Giri-Rachman, Al Mirahma Febri Kurnianti, Rizarullah, Aditya Hanung Setyadi, Anita Artarini, Marselina Irasonia Tan, Catur Riani, Dessy Natalia, Reza Aditama, Husna Nugrahapraja

“…Additionally, mRNA codon optimization was performed to enhance vaccine expression efficiency, and secondary structure analysis indicated that the designed mRNA vaccine possessed a stable conformation. …”
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Temporal changes in fecal swine microbiome primarily reflect Salmonella Typhimurium challenge and poor sanitary housing conditions, even with functional amino acid supplementation by Antonio Diego Brandão Melo, Antonio Diego Brandão Melo, Graziela Alves da Cunha Valini, Qinnan Yang, Qinnan Yang, Marllon José Karpeggiane de Oliveira, Danilo Alves Marçal, Pedro Righetti Arnaut, Ismael França, Cleslei Alisson Silva, Nate Korth, Nate Korth, Natasha Pavlovikj, Paulo Henrique Reis Furtado Campos, Henrique Gastmann Brand, John Kyaw Htoo, Andrew K. Benson, Andrew K. Benson, Luciano Hauschild, Joao Carlos Gomes-Neto, Joao Carlos Gomes-Neto, Joao Carlos Gomes-Neto

“…Network and correlation structural analysis further revealed a sub-structuring of the data, with positive correlations forming in the POOR SC group: Sub-cluster 1 (Romboutsia, Turicibacter, Clostridium sensu stricto 1, Terrisporobacter, and Intestinibacter) and Sub-cluster 2 (Dorea, Subdoligranulum, Ruminococcus torques, Blautia, Holdemanella, and Solobacterium). …”
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Cross-neutralization of Influenza A by SARS-CoV-2 specific neutralizing antibodies and polyclonal plasma: Is pre-exposure to SARS-CoV-2 protective against Influenza A? by Mohammad Mamun Alam, Asma Salauddin, Sayra Moni, Md Belayet Hasan Limon, Raisha Musarrat, Sagar Bosu, Mohammad Enayet Hossain, Mohammed Ziaur Rahman, Mustafizur Rahman

“…The SARS-CoV-2 genomes were sequenced using Illumina next-generation sequencing, and an in-silico protein structural analysis was performed to identify epitope and antibody binding similarities between SARS-CoV-2 and influenza viruses. …”
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QTL mapping associated with Verticillium wilt resistance in cotton based on MAGIC population by Muhammad Ayyaz, Zewei Chang, Shugen Ding, Peng Han, Lin Xu, Abudurezike Abudukeyoumu, Irfan Ali Siddho, Zhibo Li, Hairong Lin, Jianwei Xu, Yuanlong Wu, Xinhui Nie

“…Families with higher ARDI values, indicating stronger resistance, were more common, likely due to genetic diversity and environmental factors. Population structure analysis divided the MAGIC population into three subgroups, with Group I showing higher genetic variation and Groups II and III displaying more uniform resistance performance. …”
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Structural basis for spermidine recognition and modulation of Acinetobacter baumannii multidrug efflux regulator AmvR by Na Wang, Xu Wang, Mengxiang Zhou, Qingsong Lu, Yaling Xu, Ying Wang, Haiyun Wang, Beibei Yang, Shibing He, Liuliu Xu, Jie Li, Honghua Ge, Jinming Ma

“…Through detailed structural analysis and functional assays, we have pinpointed the critical residues in AmvR responsible for substrate recognition, providing a foundation for the development of future inhibitors.…”
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Genome-wide identification of the Sec14 gene family and the response to salt and drought stress in soybean (Glycine max) by Jinyu Zhang, Liying Zou, Li Wang, Dongchao Zhang, Ao Shen, Yongqi Lei, Maoni Chao, Xinjuan Xu, Zhiwei Xue, Zhongwen Huang

“…Based on the classification method used for Arabidopsis Sec14 members, GmSec14s can be categorized into three classes: GmPITP1 to GmPITP37, GmSFH1 to GmSFH25, and GmPATL1 to GmPATL15. Structural analysis of the GmSec14 genes revealed that the SFH subfamily contained more introns than the other subfamilies. …”
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CD200R1 immune checkpoint blockade by the first-in-human anti-CD200R1 antibody 23ME-00610: molecular mechanism and engineering of a surrogate antibody by Cristina Melero, S. Jimmy Budiardjo, Anahita Daruwalla, Lance Larrabee, Oleg Ganichkin, Alexander J. Heiler, Jill Fenaux, Ben Chung, Germaine Fuh, Yao-Ming Huang

“…We used phage display libraries of 23ME–00610 variants with individual CDR residues randomized to all 20 amino acids, from which we identified mutations that switched on MfCD200R1 binding. Structural analysis suggests how the surrogate, named 23ME–00611, acquires the ortholog binding ability at the equivalent epitope of 23ME–00610. …”
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AAAP gene family evolution and transcriptional regulation in Eucalyptus grandis under nitrogen, phosphate and boron deficiencies by Jiahui Wei, Yi Han, Huiming Xu, Lichuan Deng, Lu Li, Shasha Zhang, Ting Jiang, Yunzhuo Feng, Liuyin Ma

“…., Eucalyptus AAPs) and algal ancestors as pivotal drivers of functional diversification during early land plant adaptation. Structural analysis revealed subfamily-specific features, including conserved motifs, domain variations, and exon-intron heterogeneity, underpinning functional divergence. …”
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Multi-dimensional perspectives on sustainability in domestic waste management by Y. Ismail, R. Adji, A.D. Santoso, S. Wahyono, M.A. Kholiq, T. Handayani, S.D.R. Pahri, S. Putiamini, R.A. Pratama, F. Nurfatriani, F.L. Sahwan, F. Suryanto, Prasetiyadi , R.D. Tilottama

“…The results were classified into four sustainability levels: unsustainable, less sustainable, fairly sustainable, and sustainable, which facilitated a structured analysis of the system’s performance.FINDINGS: The analysis indicates moderate sustainability across all dimensions, with economic sustainability scoring the highest at 55.27 percent signifying its role as the system's backbone. …”
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Strain Characteristics of Motianling Ductile Shear Zone in Northern Guangxi and its Tectonic Significances by Zhili REN, Ya QIN, Zuohai FENG, Jie WU, Shiyun LIU, Qiaofan HU, Yuming BAI, Pengcheng ZHOU

“…In this article, the strain characteristics and tectonic significance of the tile shear zone of Motianling are discussed through macro-microstructure, finite strain measurement of rocks and EBSD structural analysis of quartz. The results show that the Motianling ductile shear zone has typical macro-micro ductile deformation fabrics, including mylonite foliation, rotating porphyry system, S-C fabric, domino structures, asymmetric ocular sphere, quartz dynamic recrystallization, core-mantle structure, mica fish, feldspar mechanical twinning and asymmetric pressure shadow. …”
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Analysis of genetic diversity of Zymoseptoria tritici populations in central and south-eastern Ethiopia by Ayantu Tucho, Ayantu Tucho, Tilahun Mekonnen, Farideh Ghadamgahi, Samrat Ghosh, Diriba Muleta, Kassahun Tesfaye, Kassahun Tesfaye, Eu Shang Wang, Tesfaye Alemu, Ramesh Raju Vetukuri

“…This study aimed at molecular identification and genetic structure analysis of 200 isolates of Z. tritici representing six populations in central and south-eastern regions of Ethiopia. …”
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Sm2O3-induced superconductivity enhancements in bulk Y-123 ceramics synthesized via a novel modified thermal decomposition method by Ryad Alhadei Mohamed Arebat, Mohd Mustafa Awang Kechik, Yap Siew Hong, Chen Soo Kien, Lim Kean Pah, Hussien Baqiah, Fatma Barood, Syahrul Humaidi, Hoo Keong Peh, Abdul Halim Shaari, Muhammad Kashfi Shabdin, Muralidhar Miryala

“…This study presents a novel modified thermal decomposition (MTD) technique for the synthesis of bulk YBa2Cu3O7-δ (Y-123) ceramics with varying samarium oxide (Sm2O3) additions (0.0,0.1,0.3,0.5, 1.0 and 5.0 wt%) under ambient conditions. A structural analysis via X-ray diffraction (XRD) with Rietveld refinement confirmed the dominant formation of the orthorhombic Y-123 phase, accompanied by minor secondary phases, such as Y2BaCuO5 (Y-211) and BaCuO2. …”
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Micro-credentials as an alternative means of recognising qualifications in education by A. A. Muravyeva, O. N. Oleynikova

“…It also involves a diachronic examination of the formation of various aspects of micro-credentials in subsystems and a system-structural analysis of the development of the genesis of micro-credentials. …”
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Assessing Wolbachia circulation in wild populations of phlebotomine sand flies from Spain and Morocco: implications for control of leishmaniasis by Andrés Torres-Llamas, Victoriano Díaz-Sáez, Manuel Morales-Yuste, Patricia Ibáñez-De Haro, Arturo Enrique López-López, Victoriano Corpas-López, Francisco Morillas-Márquez, Joaquina Martín-Sánchez

“…Five Wolbachia haplotypes distributed in the known A and B supergroups were identified. Structural analysis showed a nine-amino acid insertion in the fourth loop of a Wolbachia haplotype found in P. sergenti specimens from El Borouj (Morocco). …”
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Genomic structural variation in an alpha/beta hydrolase triggers hybrid necrosis in wheat by Yaoqi Si, Huaizhi Zhang, Shengwei Ma, Shusong Zheng, Jianqing Niu, Shuiquan Tian, Xuejia Cui, Keyu Zhu, Xiaocui Yan, Qiao Lu, Zhimeng Zhang, Tingting Du, Ping Lu, Yongxing Chen, Qiuhong Wu, Jingzhong Xie, Guanghao Guo, Mengjun Gu, Huilan Wu, Yiwen Li, Chengguo Yuan, Zaifeng Li, Zhiyong Liu, Lingli Dong, Hong-Qing Ling, Miaomiao Li

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Characterization of a MERS-related betacoronavirus in Danish brown long-eared bats (Plecotus auritus) by Camille Melissa Johnston, Vithiagaran Gunalan, Hans J. Baagøe, Anna S. Fomsgaard, Charlotta Polacek, Morten Rasmussen, Louise Lohse, Thomas Bruun Rasmussen

“…The receptor-binding potential of the spike protein to human DPP4, ACE2, and bat ACE2 orthologs was assessed through phylogenetic analysis of the receptor-binding domain (RBD), alongside homology modeling and structural analysis. Results Three samples tested positive for CoVs. …”
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Numerical simulation optimization analysis and field test for large deformation control of soft rock in Tabaiyi Tunnel by Jieli LI, Jiaguo ZHANG, Quansheng CHEN, Rui AO, Jihao SUN, Pengxiao GUAN

“…The deformation and damage mechanism of the surrounding rock was studied by field investigation, rock structure analysis and numerical simulation. The surrounding rock is strongly—fully and moderately weathered metamorphic sandstone sandwiched with schist and slate mainly. …”
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Epitope mapping targeting the K205R protein of African swine fever virus using nanobody as a novel tool by Xuedan Wei, Fengxia Zhang, Qiming Pei, Aijuan Shen, Duoxing Niu, Yaci Zhang, Ziheng Zhang, Yunshuo Lu, Angke Zhang, Gaiping Zhang, Hong Duan

“…Two epitopes 1MVEPR5 and 188RTQF191 were further identified, with highly conserved in different ASFV strains, and could interact with inactivated ASFV-positive sera, indicating that the two epitopes were natural linear B-cell epitopes. Moreover, structural analysis indicated that both epitopes were exposed on the surface of the K205R molecule. …”
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Leveraging machine learning in nursing: innovations, challenges, and ethical insights by Sophie So Wan Yip, Sheng Ning, Niki Yan Ki Wong, Jeffrey Chan, Kei Shing Ng, Bernadette Oi Ting Kwok, Robert L. Anders, Simon Ching Lam

“…Articles were categorized into themes, such as patient care, nursing education, operational efficiency, ethical considerations, and future potential, thus facilitating a structured analysis.ResultsFindings demonstrate that ML has significantly enhanced patient monitoring, predictive analytics, and preventive care. …”
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