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2161
Structural stability, electronic, and thermodynamic insights into Ribociclib encapsulation in PEG-functionalized ZnO nanocarriers
Published 2025-10-01“…Configuration II demonstrates superior binding affinity, with an adsorption energy of −0.88 eV compared to −0.76 eV for Configuration I, attributed to optimized interfacial interactions, including dual Zn-O coordination (2.1–2.3 Å) and multiple hydrogen bonds (2.7–2.9 Å). Electronic structure analysis reveals a reduced energy gap (3.15 eV vs. 3.30 eV) and enhanced charge transfer in Configuration II, supported by a higher dipole moment (7.0 D vs. 6.6 D) and increased electrophilicity (7.36 eV vs. 7.10 eV). …”
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2162
CONTEXTUAL DIMENSIONS OF M. PRODANOVYCH`S NOVELS POETICS
Published 2021-12-01“…The study is based on the performance of comparative-historical and genetic-typological methods in combination with structural analysis and cultural semiotic approach. M. Prodanovic`s work has not only a chronological connection with the era and the concept of postmodernism in Serbian literature. …”
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2163
A New Quasi‐Solid Polymer Electrolyte for Next‐Generation Na–O2 Batteries: Unveiling the Potential of a Polyamide‐Polyether System
Published 2025-08-01“…Pebax1657 QSPE exhibits high ionic conductivity (6.57 × 10−4 S cm−1 at room temprerature ‐ RT), an oxidation onset potential of 4.69 V versus Na/Na⁺, and an enhanced Na⁺ transference number (tNa⁺ ≈ 0.40). Structural analysis (Raman spectroscopy, differential scanning calorimetry, X‐ray diffraction, small‐angle X‐ray scattering) confirms reduced PEO crystallinity and formation of orderly nanodomains, facilitating Na⁺ transport. …”
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2164
Genetic Differentiation and Selection Signatures Revealed by Two Successive Genomic Selection of Large Yellow Croaker Against Parasite Cryptocaryon irritans
Published 2025-06-01“…Genomic Estimated Breeding Values (GEBVs) showed steady increases across the three consecutive generations, while genetic structure analysis revealed progressive population differentiation resulting from the two rounds of GS. …”
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2165
Complementary detection strategies for circulating tumor cells in breast cancer: clinical implications of combining immunofluorescence and cytopathological staining
Published 2025-07-01“…The IF staining supported the identity of CTCs detected on Giemsa-stained slides by employing a three-color antibody panel-based approach and allowed detailed phenotypic discrimination and structural analysis of CTCs, including the identification of a distinctive CK polarization pattern suggestive of a transitional state during intravasation.ConclusionGiemsa and IF may thus be complementary rather than mutually exclusive and relying on a single detection approach could underestimate the true CTC burden. …”
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2166
Geology and Zircon U-Pb Geochronology of the Las Cruces Intrusive Suite, B.C.S., México
Published 2024-11-01“…The gabbro is the oldest intrusive unit, with previous U-Pb zircon ages reported near 109 ± 2.3 and 102.3 ± 2.9 Ma. Structural analysis indicates that the gabbro and tonalite were emplaced during an E–W synmagmatic compressional event, evidenced by N–S oriented magmatic foliation, aligning subparallel to the granite and metasedimentary screens contacts. …”
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2167
Bio-Based Polyurethane Asphalt Binder with Continuous Polymer-Phase Structure: Critical Role of Isocyanate Index in Governing Thermomechanical Performance and Phase Morphology
Published 2025-06-01“…During curing, higher isocyanate indices reduced final conversions but enhanced the storage modulus and glass transition temperatures, indicating improved rigidity and thermal resistance. Phase structure analysis demonstrated that increasing NCO/OH ratios reduced bitumen domain size while improving dispersion uniformity. …”
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2168
MtDNA genetic diversity and phylogeographic insights into giant domestic pigeon (Columba livia domestica) breeds: connections between Central Europe and the Middle East
Published 2024-12-01“…The highest genetic diversity was found in the Carpathian Basin, and the lowest in the Iraqi region. STRUCTURE analysis revealed low structurality, K=3 was the most likely. …”
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2169
Genome-wide identification and association analysis of informative SNPs of various nutri-nutraceutical traits in Buckwheat (Fagopyrum spp.)
Published 2025-04-01“…Candidate gene analysis identified 138 genes within 100 kb of significant quantitative trait loci (QTLs), involved in metabolic and biosynthetic pathways such as amino acid and carbohydrate metabolism. Population structure analysis grouped the genotypes into three populations, enhancing the reliability of marker-trait associations. …”
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2170
Seven New Irbesartan Salts: Significantly Improved Dissolution, Excellent Hygrothermal Stability, and Characteristic Supramolecular Synthons
Published 2025-04-01“…Single crystal structure analysis confirmed proton transfer from coformers’ sulfonic/carboxylic acids (deprotonation site, H-out) to IRB’s diazaheterocycles (protonation site, H-in) in IRB salts. …”
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2171
Genomic architecture of purebred and crossbred Moghani lambs with Texel and Booroola sheep
Published 2025-07-01“…Genotyping-by-sequencing (GBS) was used to assess genetic diversity, admixture patterns, and selection signatures. Structure analysis revealed complex admixture in BMM and BRM, while TDM and TTM were more homogeneous. …”
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2172
Facilitating convergence research on water resource management with a collaborative, adaptive, and multi-scale systems thinking framework
Published 2025-03-01“…The specific methods applied within the framework included a six-session workshop on systems thinking, conceptual model development exercises with a longer-term subgroup, a structural analysis of system variables, and classroom-based projects. …”
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2173
Hepatocyte nuclear factor 4-α is necessary for high fat diet-induced pancreatic β-cell mass expansion and metabolic compensations
Published 2024-12-01“…Glucose intolerance and insulin resistance were exacerbated in KO mice, highlighting their inability to adapt to increased metabolic demand. Structural analysis showed that KO mice failed to exhibit HFD-induced β cell mass expansion, resulting in reduced islet diameter and number, confirming the critical role of HNF4α in β cell adaptation.SignificanceThis study demonstrates that HNF4α is essential for the proper metabolic and structural adaptation of pancreatic β-cells in response to an obesogenic environment. …”
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2174
An enhanced dual detection of DMB-labeled sialic acids using high-resolution accurate mass spectrometry and fluorescence detection
Published 2025-01-01“…We then assessed MS and fluorescence detection (FLD) sensitivity using Neu5Ac, Neu5Gc, and Kdn standards, determining detection limits of 32 fmol for MS and 320 amol for FLD, with 320 fmol needed for CID-based structural analysis. These findings highlight the complementary nature of fluorescence and mass spectrometry techniques for DMB-labeled sialic acids identification and quantification. …”
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2175
THE ARTISTIC POTENTIAL OF CHORAL CONDUCTING IN CONTEMPORARY UKRAINE
Published 2025-07-01“…As part of the methodological approach to the study, a comparative and structural analysis was applied, including the processing of statistical data on choral performances on the YouTube platform, as well as an analysis of the use of modern technologies in Ukrainian music institutions based on open sources. …”
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2176
Dual-Branch Luminance–Chrominance Attention Network for Hydraulic Concrete Image Enhancement
Published 2025-07-01“…Inspired by human visual perception, the network simultaneously improves global contrast and preserves fine-grained defect textures, which are essential for structural analysis. The proposed architecture consists of a Luminance Adjustment Branch (LAB) and a Chroma Restoration Branch (CRB). …”
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2177
Association mapping for total phenols, total flavonoids and antioxidant activity in a Mesoamerican bean diversity panel
Published 2025-04-01“…After removing SNPs with high linkage disequilibrium, 707 SNPs were retained for population structure analysis. In total, 147 unique QTNs were significant for the three biochemical traits studied (TPC, FLA, and DPPH), of which 41 were detected at least twice by one of the seven multi-locus methods used or in different environments analyzed (Londrina, Guarapuava, and LSmeans). …”
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2178
Molecular profiling and sex determination of Cannabis sativa germplasm collection: Exploring microsatellite markers and high-resolution melting (HRM) analysis
Published 2025-08-01“…Utilizing 10 microsatellite markers, important genetic variation was observed among the samples. Population structure analysis using STRUCTURE software indicated four distinct genetic subpopulations, which were further supported by the principal coordinate analysis (PCoA). …”
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2179
Biosynthesis of the benzylpyrrolidine precursor in anisomycin by a unique ThDP-dependent enzyme
Published 2025-03-01“…To the best of our knowledge, siAniP is the first TK that catalyzes the transfer of a C2 ketol and symmetrical intermolecular coupling using aromatic keto acids as donor substrates. Structural analysis, docking model construction, and site-directed mutagenesis identified that I220, H275, R322 and W391 were crucial for substrate binding. …”
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2180
Combined impact of semantic segmentation and quantitative structure modelling of Southern pine trees using terrestrial laser scanning
Published 2025-07-01“…Addressing this gap, our study evaluates the performance of multiple segmentation algorithms on TLS data from southern pines, providing valuable insights into improving structural analysis and supporting more precise and efficient forest research and monitoring methodologies. …”
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