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31241
Is The SARS-CoV2 Evolved in Human Being: A prospective Genetic Analysis
Published 2020-12-01“…The phylogenetic trees for all human coronaviruses with the novel Coronavirus have been built using a several complete amino acid sequences of the four known structural proteins, S (spike), E (envelope), M (membrane), and N (nucleocapsid). …”
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31242
dyphAI dynamic pharmacophore modeling with AI: a tool for efficient screening of new acetylcholinesterase inhibitors
Published 2025-02-01“…Experimental results revealed that molecules, 4 (P-1894047), with its complex multi-ring structure and numerous hydrogen bond acceptors, and 7 (P-2652815), characterized by a flexible, polar framework with ten hydrogen bond donors and acceptors, exhibited IC₅₀ values lower than or equal to that of the control (galantamine), indicating potent inhibitory activity. …”
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31243
The effect of Ocimum basilicum on the prevention of postpartum depression symptoms and sleep quality: A triple-blind randomized controlled clinical trial
Published 2025-01-01“…The EPDS and postpartum sleep quality scale were completed through structured interviews at eight weeks postpartum. The Mann-Whitney U test was used to compare the mean postpartum depression scores before and after the intervention, and ANCOVA was used to compare the mean postpartum sleep quality scores. …”
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31244
Is there a mental health diagnostic crisis in primary care? Current research practices in global mental health cannot answer that question
Published 2025-01-01“…We recommend evaluating multiple conditions, statistically adjusting prevalence estimates generated from self-report tools, and consistently using structured clinical interviews as a gold standard. We propose clinically meaningful detection as ‘good-enough’ diagnoses incorporating multiple conditions accounting for context, health system and types of interventions available. …”
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31245
Challenges and barriers to physician decision-making for prescribing and deprescribing among patients with multimorbidity in eastern China’s primary care settings: a qualitative st...
Published 2025-02-01“…We aimed to investigate the experiences and perceptions of primary care physicians (PCPs) regarding their decision-making processes in prescribing and deprescribing medications for patients with multimorbidity, and identify the challenges and barriers they face.Design From 5 October 2023 to 27 January 2024, this qualitative study was conducted through semi-structured interviews that encouraged in-depth exploration of the participants’ experiences and perspectives. …”
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31246
Transfer from long-term care to acute care and risk of new permanent cognitive or physical disability among long-term care residents in Canada: protocol for a retrospective cohort...
Published 2025-01-01“…We will fit marginal structural models (MSMs) to account for the known shortcomings of traditional regression modelling, such as collider bias. …”
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31247
Silicon-based all-solid-state batteries operating free from external pressure
Published 2025-01-01“…Such an efficient ionic/electronic transport system also facilitates the uniform release of cycling expansion stresses from the Si particles and stabilizes bulk-phase and interfacial structure of anode. Consequently, the Li21Si5/Si–Li21Si5 anode exhibited a critical current density of 10 mA cm−2 at 45 °C with a capacity of 10 mAh cm−2. …”
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31248
“Sleepless nights are a daily reality for us” how women experiencing homelessness in Addis Ababa, Ethiopia describe street life: a photovoice study
Published 2025-02-01“…In this study, we aimed to describe women’s experiences of street homelessness in their own terms and their suggestions to address their unmet needs.MethodsThis photovoice study draws on photos, focus group discussions, and semi-structured interviews. We conducted the study in collaboration with women in their reproductive years experiencing homelessness (n = 9). …”
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31249
Isoxazole-based molecules restore NK cell immune surveillance in hepatocarcinogenesis by targeting TM4SF5 and SLAMF7 linkage
Published 2025-01-01“…We used comprehensive structure activity relationship analysis to identify TM4SF5-specific isoxazole (TSI)-based small molecules that inhibit TM4SF5-mediated effects. …”
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31250
A preliminary investigation into self-compassion and compassion-based intervention for mental health in the performing arts
Published 2025-02-01“…Descriptive pre-post data combined with thematic analysis of semi-structured interview transcripts identified performer perspectives of the compassion-based intervention.ResultsIn Study 1, 211 participants were included in the final cross-sectional analysis, which showed that the intention to be self-compassionate was associated with lower symptoms of depression and anxiety, and higher wellbeing, even while controlling for several key demographic and risk factors (stress, alcohol use, and body appreciation). …”
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31251
Surface prereacted glass-ionomer particles incorporated into resin composites promote biocompatibility for restoration of subgingival dental defects
Published 2025-04-01“…Surface prereacted glass ionomer (S-PRG) is a novel glass particle characterized by a three-layered structure and the release of multiple ions with bioactive potential. …”
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31252
The externalization of internal experiences in psychotherapy through generative artificial intelligence: a theoretical, clinical, and ethical analysis
Published 2025-02-01“…To address these challenges, we propose the SAFE-AI protocol, offering clinicians structured guidelines for responsible AI integration in therapy. …”
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31253
Monitoring changes of forest height in California
Published 2025-01-01“…Mapping and monitoring the structure of these forests at high spatial resolution provides the necessary data to better manage forest health, mitigate wildfire risks, and improve carbon sequestration. …”
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31254
One-Pot Synthesis and Enhanced Vis-NIR Photocatalytic Activity of NiTiO<sub>3</sub>/TiO<sub>2</sub> Templated by Waste Tobacco Stem-Silks
Published 2025-01-01“…The boosting photocatalytic activity has been shown to be attributed to efficient charge separation and transfer across a direct Z-scheme heterojunction between NiTiO<sub>3</sub> and TiO<sub>2</sub> and enhanced light-harvesting ability of special flaky structure reduplicated from tobacco stem-silks. This reported strategy provides a new idea for the multifunctional utilization of waste tobacco stem-silks and the synthesis of novel photocatalysts for the potential application in wastewater treatment.…”
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31255
A new phase of China-ASEAN health cooperation: the China-ASEAN Beijing Declaration on Cooperation in Innovation of Health Products and Technologies
Published 2025-01-01“…Abstract Utilizing innovative methods to advance the research and development (R&D) of health products and enhance their accessibility has become crucial to achieving universal health coverage, addressing public health emergencies, and promoting population health and wellbeing. However, structural contradictions do exist in the supply and demand of health products in the Association of Southeast Asian Nations (ASEAN). …”
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31256
Dutch Validation of the Self-Evaluation of Negative Symptoms Scale (SNS)
Published 2024-12-01“…CFA confirmed the five-factor structure of the SNS. The SNS was significantly correlated (all <i>p</i> < 0.001) with the PANSS positive (r = 0.31), PANSS negative (r = 0.33), HoNOS (r = 0.37), FR (r = 0.27) and the ManSA (r = −0.40). …”
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31257
Preclinical optimization of a GPC2-targeting CAR T-cell therapy for neuroblastoma
Published 2023-01-01“…We developed a new chimeric antigen receptor (CAR) targeting glypican-2 (GPC2) and conducted iterative preclinical engineering of the CAR structure to maximize its anti-tumor efficacy before clinical translation.Methods We evaluated different GPC2-CAR constructs by measuring the CAR activity in vitro. …”
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31258
Advancements in lamb wave high-frequency devices using diamond-like carbon (DLC) coatings
Published 2025-06-01“…Lamb wave devices, vital in sensing, communication, and structural health monitoring, require efficient surface acoustic wave (SAW) propagation for their diverse applications. …”
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31259
Retinal thickness and vascular density changes in Keratoconus: A systematic review and meta-analysis
Published 2025-01-01“…Conclusion: In KC patients, significant alterations in retinal structure and vascular density have been observed. …”
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31260
Prevalence and Risk Factors of Helicobacter pylori Infection among Children Aged 1 to 15 Years at Holy Innocents Children’s Hospital, Mbarara, South Western Uganda
Published 2019-01-01“…After obtaining informed consent from parents/legal guardians, illegible children who presented with gastrointestinal complaints at Holy Innocents Children’s Hospital were recruited; structured questionnaires were administered to the parents/guardians to collect information on sociodemographic data and risk factors of H. pylori infection. …”
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