Engineered biomimetic cisplatin-polyphenol nanocomplex for chemo-immunotherapy of glioblastoma by inducing pyroptosis by Xinyan Hao, Yucheng Tang, Wenjie Xu, Ming Wang, Jiayi Liu, Yongjiang Li, Jun He, Yanjin Peng, Pengcheng Sun, Dehua Liao, Xiongbin Hu, Tiantian Tang, Min Zhou, Ruyue Han, Jiemin Wang, João Conde, Daxiong Xiang, Junyong Wu

“…For the effective delivery of CDDP, the CDDP-polyphenol nanocomplexes were prepared, and catalase and copper ions were incorporated to fortify structural integrity, enhance glutathione (GSH) responsiveness, and ameliorate tumor hypoxia. …”
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Six-Phase Fully Coreless Axial-Flux Permanent-Magnet Generator: Design, Fabrication, and Performance Analysis by Turki M. Alsuwian, Asiful Habib, Muhammad Ammirrul Atiqi Mohd Zainuri, Ahmad Asrul Ibrahim, Nasrudin Abd Rahim, Adam R. H. Alhawari, Abdulkarem H. M. Almawgani, Saleh Almasabi, A. T. Hindi, Mohamed Fauzi Packeer Mohamed

“…Nevertheless, the proliferation of coreless AFPM machines faces hurdles as to high leakage flux and weaker structural integrity. Additionally, adopting multi-phase setups in AFPM introduces challenges, requiring additional winding coils and enlarging the stator diameter, leading to bulkier machine designs. …”
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Increased cardiac macrophages in Sorbs2-deficient hearts: revealing a potential role for macrophage in responding to embryonic myocardial abnormalities by Beibei Hu, Xiangyang Liu, Xiangyang Liu, Xiangyang Liu, Shanshan Xiong, Qin Gong, Junjie Yang, Hongjun Shi, Hongjun Shi, Hongjun Shi, Min Zhang, Fei Liang, Zhen Zhang, Zhen Zhang

“…Additionally, a non-significant increase in septal defects in macrophage-depleted Sorbs2−/− hearts suggests a potential reparative function for macrophages in maintaining structural integrity. Valve formation, however, remained unaffected. …”
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Molecular Crosstalking among Noncoding RNAs: A New Network Layer of Genome Regulation in Cancer by Marco Ragusa, Cristina Barbagallo, Duilia Brex, Angela Caponnetto, Matilde Cirnigliaro, Rosalia Battaglia, Davide Barbagallo, Cinzia Di Pietro, Michele Purrello

“…Moreover, the pivotal role of ncRNAs as keystones of network structural integrity makes them very attractive and promising targets for innovative RNA-based therapeutics. …”
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Green synthesis of magnetic type Zeolites 4A as catalyst for the elimination of quinoline yellow by the Fenton process: Optimization and kinetic investigation by Roland Urselin Noumsi Foko, Cyrille Ghislain Fotsop, Donald Raoul Tchuifon Tchuifon, Charles Banenzoué, Anatole Guy Blaise Azebaze

“…The characterization results of the material after degradation show that it maintains its structural integrity after use.…”
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Optimization design of an acoustic cover layer for a cylindrical cavity based on porous materials by Bohan ZHANG, Jili RONG, Xiuyan CHENG

“…Vibration suppression is critical for protecting the structural integrity of the payload fairing and the equipment housed within it. …”
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Ultrasound-assisted modification of oat protein isolates: Structural and functional enhancements by Hamad Rafique, Pai Peng, Xinzhong Hu, Kanza Saeed, Muhammad Zubair Khalid, Waseem Khalid, Sonia Morya, Tawfiq Alsulami, Robert Mugabi, Gulzar Ahmad Nayik

“…Moderate ultrasonic treatment (400 W) promoted protein dissolution, and maintained a good balance between β-sheets (71.04 ± 0.08), α-helix (16.27 ± 0.02) and β-turns (12.68 ± 0.03), exhibiting optimized flexibility and structural integrity. Whereas, higher strength (600 W) significantly destroyed protein structure. …”
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One-pot synthesis and characterization of a BSA-Cu2S/CuS quantum dots drug delivery system based on biuret’s reaction by Porfirio Estrada-Rojas, Juan Francisco Hernández-Paz, Claudia Alejandra Rodríguez-González, Mónica Elvira Mendoza-Duarte, Santos Adriana Martel-Estrada, Laura Elizabeth Valencia-Gómez, Héctor Camacho-Montes, Imelda Olivas-Armendáriz

“…Fourier-transform infrared (FTIR) spectroscopy confirmed the structural integrity of BSA after functionalization, while x-ray diffraction (XRD) analysis verified the formation of CuS and Cu _2 S crystals. …”
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Distribution and environmental drivers of macrofaunal nematode communities across gradients of methane seepage at cold seeps on Hikurangi Margin (New Zealand) and potential implica... by Daniel Leduc, Ashley A. Rowden, Ashley A. Rowden, Sarah Seabrook, David A. Bowden, Andrew R. Thurber, Andrew R. Thurber, Jane Halliday, Cliff S. Law, Cliff S. Law, Olivia S. Pereira, Bethany G. Whitten, Andrew Marriner

“…Impact on seep communities from gas hydrate extraction processes may occur via reduction or potentially cessation of free-gas methane supply to the seafloor, ‘sand’ production at the seafloor due to the physical degradation of the substrate structure, or alteration of the structural integrity of the seafloor substrate. Any spatial management options considered for managing these impacts should reflect the differences in benthic community structure between depths and locations on the Hikurangi Margin.…”
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Shexiang Tongxin dropping pills ameliorate myocardial ischemia-reperfusion injury progression via the S1PR2/RhoA/ROCK pathway by Ying Sun, Boyang Jiao, Yizhou Liu, Ran Wang, Qiong Deng, David N. Criddle, Yulin Ouyang, Wei Wang, Xuegong Xu, Chun Li

“…STDP enhanced the structural integrity of coronary microvascular positioning and distribution by clarifying and completing TJs and increasing the expression of ZO-1, occludin, claudin-5, and VE-cadherin in vivo (all P < .05). …”
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An inner membrane complex protein IMC1g in Plasmodium berghei is involved in asexual stage schizogony and parasite transmission by Yinjie Liu, Shitong Cheng, Gang He, Dawei He, Duo Wang, Sicong Wang, Lumeng Chen, Liying Zhu, Yonghui Feng, Liwang Cui, Yaming Cao, Xiaotong Zhu

“…Together, this work reveals an essential role of IMC1g in the parasite life cycle and suggests that IMC1 family members likely contribute to parasite gliding and invasion.IMPORTANCEThe malaria parasite’s inner membrane complex is critical to maintain its structural integrity and motility. Here, we identified the function of the IMC1g protein, a member of the IMC1 family, in invasive and proliferative stages of P. berghei. …”
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Thermoresponsive Gels with Rosemary Essential Oil: A Novel Topical Carrier for Antimicrobial Therapy and Drug Delivery Applications by Ludovic Everard Bejenaru, Adina-Elena Segneanu, Cornelia Bejenaru, Ionela Amalia Bradu, Titus Vlase, Dumitru-Daniel Herea, Marius Ciprian Văruţ, Roxana Maria Bălăşoiu, Andrei Biţă, Antonia Radu, George Dan Mogoşanu, Maria Viorica Ciocîlteu

“…PLGA microparticles were synthesized through an optimized oil-in-water emulsion technique, ensuring high encapsulation efficiency and structural integrity. These microparticles were thoroughly characterized using Fourier-transform infrared (FTIR) spectroscopy to confirm functional group interactions, scanning electron microscopy (SEM) for surface morphology, X-ray diffraction (XRD) for crystalline properties, and thermal analysis for stability assessment. …”
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DEVELOPMENT AND EVALUATION OF AN ANTERIORLY MOUNTED MICROPROCESSOR-CONTROLLED POWERED HIP JOINT PROSTHESIS by Kelly Brannen, Natalie Baddour, Lucas Cho, David Langlois, Patrick Dumond, Edward Lemaire

“…OBJECTIVE: To develop and validate the mechanism, structural integrity, and design of an anteriorly mounted powered hip joint prosthesis. …”
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Unraveling the impact of SARS-CoV-2 mutations on immunity: insights from innate immune recognition to antibody and T cell responses by Rafael Bayarri-Olmos, Rafael Bayarri-Olmos, Adrian Sutta, Adrian Sutta, Anne Rosbjerg, Anne Rosbjerg, Mie Mandal Mortensen, Charlotte Helgstrand, Per Franklin Nielsen, Laura Pérez-Alós, Beatriz González-García, Laust Bruun Johnsen, Finn Matthiesen, Thomas Egebjerg, Cecilie Bo Hansen, Alessandro Sette, Alessandro Sette, Alba Grifoni, Ricardo da Silva Antunes, Peter Garred, Peter Garred

“…Notably, we identified two glycan sites (N717 and N801) as potentially essential for the structural integrity of the spike protein. We also evaluated the antibody and T cell responses. …”
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N-acetylcysteine increased the growth performance of Leuciscus waleckii by improving mitochondrial function, enhancing antioxidant and anti-inflammatory, and inhibiting apoptosis i... by Deng Lai Li, Rui Zhu, Si Tong Meng, Yin Tao Wang, Si Ying Liu, Zhi Yong Yang, Li Fang Wu

“…HE staining results showed that NAC maintained the morphological and structural integrity of the hepatopancreas and intestine. …”
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Comparative Study of the Chemical Composition Disparities Between Fast-twitch and Slow-twitch Muscles in Marine Teleost Fishes by Huan WANG, Shufang LIU

“…Conversely, fast-twitch muscles, responsible for burst swimming, require more PUFA to maintain the structural integrity and functionality of cell membranes. …”
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Comparison of dark-field chest radiography and CT for the assessment of COVID-19 pneumonia by Florian T. Gassert, Henriette Bast, Henriette Bast, Henriette Bast, Theresa Urban, Theresa Urban, Theresa Urban, Manuela Frank, Manuela Frank, Felix G. Gassert, Konstantin Willer, Konstantin Willer, Rafael C. Schick, Rafael C. Schick, Bernhard Renger, Thomas Koehler, Thomas Koehler, Alexandra Karrer, Andreas P. Sauter, Alexander A. Fingerle, Marcus R. Makowski, Franz Pfeiffer, Franz Pfeiffer, Franz Pfeiffer, Franz Pfeiffer, Daniela Pfeiffer, Daniela Pfeiffer

“…BackgroundDark-field chest radiography allows the assessment of the structural integrity of the alveoli by exploiting the wave properties of x-rays.PurposeTo compare the qualitative and quantitative features of dark-field chest radiography in patients with COVID-19 pneumonia with conventional CT imaging.Materials and methodsIn this prospective study conducted from May 2020 to December 2020, patients aged at least 18 years who underwent chest CT for clinically suspected COVID-19 infection were screened for participation. …”
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Lycium barbarum glycopeptide ameliorates aging phenotypes and enhances cardiac metabolism by activating the PINK1/Parkin-mediated mitophagy pathway in D-galactose-induced mice by Tianchan Peng, Jian Xiang, Yun Tian, Xiaogen Tang, Lina Wang, Lijuan Gao, Oscar Junhong Luo, Li’an Huang, Guobing Chen

“…Mitochondrial assays revealed LbGp improved mitochondrial function and preserved structural integrity of the mitochondrial inner membrane. …”
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TRAINING OF ENGINEERING EDUCATORS AND ADDITIONAL PROFESSIONAL EDUCATION SYSTEM AS AN INTEGRATIVE BASIS FOR RESEARCH UNIVERSITY by Vasiliy G. Ivanov

“…The paper presents some results and prospects of development of the contemporary institution for additional professional education. The structure integrates a comprehensive approach to human resourcing of the engineering university on the basis of additional professional programs (professional development) for educators and industry community of the real sector of the economy. …”
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Numerical Analysis and Test Research of the Dynamic Stress of Spiral Bevel Gear by Liu Haiou, Liu Xingxing

“…The inlet gearbox spiral bevel gear of aircraft turbofan engine may result in insufficient of gear vibration margin because of the limitation of structure integration. The numerical analysis and test research of the dynamic stress of spiral bevel gear are carried out. …”
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