Effects of RARα ligand binding domain mutations on breast fibroepithelial tumor function and signaling by Xi Xiao Huang, Ley Moy Ng, Po-Hsien Lee, Peiyong Guan, Mun Juinn Chow, Aisyah Binte Mohamed Bashir, Meina Lau, Kenric Yi Shu Tan, Zhimei Li, Jason Yongsheng Chan, Jing Han Hong, Sheng Rong Ng, Tun Kiat Ko, Hong Lee Heng, Hsiang Ling Teo, Daniela Rhodes, Patrick Tan, Puay Hoon Tan, Donald P. McDonnell, Bin Tean Teh

“…X-ray crystallography revealed that the mutants maintained structural integrity, with altered co-activator recruitment explaining the loss of transcriptional function. …”
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Effect of Dry Aging on Beef Muscle Proteins by Galina V. Gurinovich, Irina S. Patrakova, Vladislav A. Khrenov, Marina V. Patshina, Antonina I. Shevchenko

“…As a result, the structural integrity of muscle fibers degraded, the meat grew tender, and the proteins became more available to digestive enzymes. …”
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A novel cryopreservation solution for adipose tissue based on metformin by Yaping Deng, Xin Liu, Xichao Jian, Yan Zhang, Yinchi Hou, Suyun Hou, Fang Qi, Shune Xiao, Chengliang Deng

“…In vivo analysis revealed the highest tissue retention rate in the TGM group, with histological examination indicating robust structural integrity. Conclusion The TGM cryopreservation solution, containing metformin, greatly preserves adipose tissue, reduces apoptosis, and improves tissue retention rates. …”
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Efficacy Study of Carrageenan as an Alternative Infused Material (Filler) in Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) Porous 3D Scaffold by Nor Syamimi Che Johari, Syazwan Aizad, Saiful Irwan Zubairi

“…The 3D infused scaffold of 4% (w/v) carrageenan concentration (S2) produced a moderate degradation rate of 0.02±1.55 (mg/day) with a sustained structural integrity up to 28 days. The carrageenan infused scaffold of 4% (w/v) was demonstrated to be the best 3D structure for a long-term cell culture (>2 weeks). …”
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Cross Flow Analysis over the Jet Pumps of a BWR-5 Reactor by G. Soto-Mendoza, A. Armenta-Molina, S. Pérez-Montejo, L.H. Hernández-Gómez, P. Ruiz-López, G.M. Urriolagoitia-Calderón, J.A. Beltrán-Fernández

“…Therefore, the structural integrity of the jet pump assemblies is maintained.…”
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Studies on the Effect of Laser Shock Peening Intensity on the Mechanical Properties of Wire Arc Additive Manufactured SS316L by Geethapriyan Thangamani, Santosh Kumar Tamang, Md Saad Patel, Jinoop Arackal Narayanan, Muthuramalingam Thangaraj, Jufan Zhang, Pardeep Kumar Gianchandani, Palani Iyamperumal Anand

“…This is due to LSP effectively enhancing the mechanical properties and structural integrity of WAAM-fabricated SS316L, reducing porosity, and refining the microstructure. …”
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In vitro and in vivo studies on bioactive hydroxyapatite-coated magnesium for glaucoma drainage implant by Huanhuan Gao, Yi Chen, Xia Chen, Liandi Huang, Hao Yao, Xiaomin Zhu, Min Tang, Yong Wang, Xiangji Li, Lin Xie

“…Magnesium (Mg) is an essential element in maintaining the functional and structural integrity of vital ocular tissues, but Mg and its alloys are rarely mentioned in ophthalmic applications. …”
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Incorporating insulin into alginate-chitosan 3D-printed scaffolds: A comprehensive study on structure, mechanics, and biocompatibility for cartilage tissue engineering by Afsaneh Jahani, Mohammad Sadegh Nourbakhsh, Ali Moradi, Marzieh Mohammadi, Lobat Tayebi

“…Histological analysis confirmed favorable biocompatibility and structural integrity of Insulin-loaded pure Alg and Alg-Cs scaffolds at drug loading levels of up to 20 and 10 μg, respectively. …”
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Effect of recycling on the time- and temperature-dependent mechanical properties of PP/MWCNT composite liner materials by Attila Bata, Péter Gerse, Krisztián Kun, Emese Slezák, Ferenc Ronkay

“…These preliminary findings reveal that recycled PP/MWCNT composites can provide structural integrity, making them suitable for high-performance applications like hydrogen storage. …”
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Mechanistic switch in corrosion behavior of magnesium alloy diamond lattice structures induced by argon plasma treatment by Viviana M. Posada, Alexandru Marin, Tonny Naranjo, Juan Ramírez, Patricia Fernández-Morales

“…This protective layer, combined with modified surface topology, initiated a core-to-periphery degradation pattern that maintained structural integrity for up to 8 wk post-implantation. These findings support the conclusion that the DPNS-treated scaffold demonstrates sustained improved corrosion resistance over time compared to the untreated control.Micro-CT revealed plasma-treated samples retained larger struts (504.9 ± 95.3 µm at 8 wk) and formed larger H2 pockets extending 14.2 mm from the implant center, versus 4.9 mm in controls. …”
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Preservation of Bilateral Corticospinal Projections from Injured Hemisphere After Perinatal Stroke by Cameron P. Casey, Ellen N. Sutter, Alina Grimaldo, Kellie M. Collins, Jose Guerrero-Gonzalez, Ryan M. McAdams, Douglas C. Dean, Bernadette T. Gillick

“…Assessments included magnetic resonance imaging (MRI) to characterize the lesion and quantify CST structural integrity, single-pulse transcranial magnetic stimulation (spTMS) to evaluate CST functional circuitry, and neuromotor assessments. …”
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Multiscale integral synchronous assembly of cuttlebone-inspired structural materials by predesigned hydrogels by Huai-Bin Yang, Yi-Xing Lu, Xin Yue, Zhao-Xiang Liu, Wen-Bin Sun, Wen-Pei Zheng, Qing-Fang Guan, Shu-Hong Yu

“…Abstract The overall structural integrity plays a vital role in the unique performance of living organisms, but the integral synchronous preparation of different multiscale architectures remains challenging. …”
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Self‐Healing Hyaluronic Acid‐based Hydrogel with miRNA140‐5p Loaded MON‐PEI Nanoparticles for Chondrocyte Regeneration: Schiff Base Self‐Assembly Approach by Wei Zhu, Han Wang, Bin Feng, Guangli Liu, Yixin Bian, Tianhao Zhao, Qi Wang, Xisheng Weng

“…To enhance the scaffold's structural integrity and gene delivery efficiency, mineralized silk fibroin and miR140‐5p‐loaded MON‐PEI nanoparticles are incorporated. …”
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Enhancing Plasticity and Compaction Properties of Clay Soil- Subgrade Using Iron Ore Tailings: A Case Study of Kabale District. by Mukago, Andrew

“…Despite the abundance of clay soils in construction projects, their plasticity and compaction properties can be detrimental to structural integrity. The main objective of this research was to enhance the plasticity and compaction properties of clay soil subgrade using iron ore tailings and the specific objectives were to determine the physical and mechanical properties of Iron Ore Tailings and Clay, study the change in the; plasticity of clay soils at different percentages of Iron Ore Tailing’s Content (10%, 20% and 30%), compaction property of clay soils at different percentages of Iron Ore Tailing’s Content and to determine the minimum percentage that gives a positive change in the enhancement of plasticity and compaction properties of clay. …”
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Influence of Abutment Screw-Tightening Methods on the Screw Joint: Immediate and Long-Term Stability by Manlin Sun, Yusen Shui, Yuqiang Zhang, Ruiyang Ma, Yuwei Zhao, Hongyu Chen, Ping Yu, Zhi Li, Tingting Wu, Haiyang Yu

“…The operating time of method A was much longer than those of methods B and C (P<0.001). The structural integrity disruption of the screw thread was observed according to the SEM results in all postloading groups. …”
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In silico development of a multi-epitope-based vaccine against Burkholderia cepacia complex using reverse vaccinology by Donya Ghorbani, Donya Ghorbani, Masoumeh Beig, Masoumeh Beig, Narjes Noori Goodarzi, Mohammad Sholeh, Mohammad Sholeh, Behzad Shahbazi, Behzad Shahbazi, Yaser Moghaddam, Farzad Badmasti

“…The MEV-TLR4 system demonstrates the greatest stability and tightly bound interaction, with minimal fluctuations and high structural integrity. In contrast, the MEV-only system exhibits significant flexibility and dynamic behavior as a free ligand, while the MEV-TLR2 system balances stability and flexibility, showing a dynamic but stable interaction.ConclusionNine potential immunogenic proteins were identified as viable targets for vaccine development. …”
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Abnormal Circadian Modification of Aδ-Fiber Pathway Excitability in Idiopathic Restless Legs Syndrome by Catello Vollono, Giacomo Della Marca, Elisa Testani, Anna Losurdo, Daniela Virdis, Diana Ferraro, Valerio Brunetti, Paolo M. Rossini, Domenica Le Pera, Salvatore Mazza, Massimiliano Valeriani

“…This study confirms the structural integrity of Aδ nociceptive system in idiopathic RLS, but it also suggests that RLS patients present circadian modifications in the pain system. …”
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Methylprednisolone substituted lipid nanoparticles deliver C3 transferase mRNA for combined treatment of spinal cord injury by Haoru Dong, Zongxing He, Shiyi Cai, Haiqiang Ma, Lili Su, Jianfeng Li, Huiying Yang, Rong Xie

“…Our findings reveal several significant advantages of this approach: Firstly, the incorporation of C3 transferase mRNA into MP-LNPs does not compromise the structural integrity of the nanoparticles, ensuring efficient mRNA expression within the spinal cord. …”
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Performance evaluation of waste glass in soil improvement: Influence of particle size of waste glass on mechanical, microstructural, and durability characteristics by Harun Akoğuz

“…Nevertheless, the WD cycling damage considerably intensified disintegration, causing a profound deterioration in the structural integrity of the samples. As a result, repeated WD cycles lead to the formation of microcracks, which progressively weaken soil aggregation and reduce the overall strength of the samples. …”
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Citronellol-functionalized natural silica: a biogenic approach for antifungal and antibacterial material applications by Guillermo P. Lopez, Guillermo P. Lopez, Leyanet Barberia Roque, Katerine Igal, Katerine Igal, Erasmo Gámez Espinosa, Erasmo Gámez Espinosa, Natalia Bellotti, Natalia Bellotti

“…IntroductionNew bioactive hybrid materials to prevent biofilm-induced biodeterioration are a significant challenge in indoor environments, where contaminants from microbial films compromise structural integrity and contribute to air pollution, posing health risks from prolonged exposure to biological agents.MethodsFor the first time, diatomaceous earth or diatomite (Dt) was functionalized with quaternary ammonium salt (QAS) and a biogenic compound, citronellol, to develop a bioactive hybrid material (Dt*QC). …”
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