3D Culture of Bone Marrow-Derived Mesenchymal Stem Cells (BMSCs) Could Improve Bone Regeneration in 3D-Printed Porous Ti6Al4V Scaffolds by Lingjia Yu, Yuanhao Wu, Jieying Liu, Bo Li, Bupeng Ma, Yaqian Li, Zhenfei Huang, Yu He, Hai Wang, Zhihong Wu, Guixing Qiu

“…We suggest that this approach provides an opportunity to further improve the efficiency of stem cell therapy for the treatment of mandibular bone defects.…”
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Human Adipose-Derived Mesenchymal Stem Cells Cryopreservation and Thawing Decrease α4-Integrin Expression by Ana Carolina Irioda, Rafael Cassilha, Larissa Zocche, Julio Cesar Francisco, Ricardo Correa Cunha, Priscila Elias Ferreira, Luiz Cesar Guarita-Souza, Reginaldo Justino Ferreira, Bassam Felipe Mogharbel, Venkata Naga Srikanth Garikipati, Daiany Souza, Mirian Perlingeiro Beltrame, Katherine Athayde Teixeira de Carvalho

“…Therefore, further studies are warranted to standardize protocols related to cryopreservation to attain full benefits of stem cell therapy.…”
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Multinational retrospective analysis of bridging therapy prior to chimeric antigen receptor t cells for relapsed/refractory acute lymphoblastic leukemia in children and young adult... by Maike Breidenbach, Peter Bader, Andishe Attarbaschi, Claudia Rossig, Roland Meisel, Markus Metzler, Marion Subklewe, Fabian Mueller, Paul-Gerhardt Schlegel, Irene Teichert von Lüttichau, Jean-Pierre Bourquin, Gabriele Escherich, Gunnar Cario, Peter Lang, Ramona Coffey, Arend von Stackelberg, Semjon Willier, Brigitte Strahm, Christina Peters, Tobias Feuchtinger

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Intranasal delivery of hMSC-derived supernatant for treatment of ischemic stroke by inhibiting the pro-inflammatory polarization of neutrophils by Yixiang Jiang, Ning Wang, Jingyi Liu, Haoran Ren, Wenkang Jiang, Yanting Lei, Xidan Fu, Miao Hao, Xiujuan Lang, Yumei Liu, Xijun Liu, Rui Li, Hulun Li

“…These results provide a theoretical basis for a deeper understanding of the mechanisms of stem cell therapy and for exploring suitable delivery pathways of stem cell treatment.…”
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Comparable outcomes after busulfan- or treosulfan-based conditioning for allo-HSCT in children with ALL: results of FORUM by Krzysztof Kalwak, Laura M. Moser, Ulrike Pötschger, Peter Bader, Katharina Kleinschmidt, Roland Meisel, Jean-Hugues Dalle, Akif Yesilipek, Adriana Balduzzi, Gergely Krivan, Evgenios Goussetis, Raquel Staciuk, Petr Sedlacek, Herbert Pichler, Peter Svec, Melissa Gabriel, Tayfun Güngör, Ernest Bilic, Jochen Buechner, Marleen Renard, Kim Vettenranta, Marianne Ifversen, Cristina Diaz-de-Heredia, Jerry Stein, Jacek Toporski, Marc Bierings, Christina Peters, Marc Ansari, Franco Locatelli

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The Histone Demethylase KDM3B Promotes Osteo-/Odontogenic Differentiation, Cell Proliferation, and Migration Potential of Stem Cells from the Apical Papilla by Chen Zhang, Xiao Han, Yuncun Liang, Huina Liu, Zhipeng Fan, Jianpeng Zhang

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lncRNA HHIP-AS1 Promotes the Osteogenic Differentiation Potential and Inhibits the Migration Ability of Periodontal Ligament Stem Cells by Qianyi Qin, Haoqing Yang, Chen Zhang, Xiao Han, Jing Guo, Zhipeng Fan, Jie Guo

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Stem Cell–Based Therapies via Different Administration Route for Stroke: A Meta-analysis of Comparative Studies by Gabriella Jeanne Mulia, Novelia Anna, John Chung-Che Wu, Hon-Ping Ma, Yung-Hsiao Chiang, Ju-Chi Ou, Kai-Yun Chen

“…These findings demonstrate the potential of stem cell therapies to improve functional recovery and survival in stroke patients, regardless of administration route. …”
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Endothelial-Mesenchymal Transition in Regenerative Medicine by Damian Medici

“…As an alternative to traditional or artificial stem cell therapies, EndMT may represent a safe method for engineering new tissues to treat degenerative diseases by mimicking a process that occurs in nature. …”
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Could Metabolic Syndrome, Lipodystrophy, and Aging Be Mesenchymal Stem Cell Exhaustion Syndromes? by Eduardo Mansilla, Vanina Díaz Aquino, Daniel Zambón, Gustavo Horacio Marin, Karina Mártire, Gustavo Roque, Thomas Ichim, Neil H. Riordan, Amit Patel, Flavio Sturla, Gustavo Larsen, Rubén Spretz, Luis Núñez, Carlos Soratti, Ricardo Ibar, Michiel van Leeuwen, José María Tau, Hugo Drago, Alberto Maceira

“…Our point of view could open the possibility for a new strategy of treatment in metabolic syndrome, lipodystrophic syndromes, progeria, and even aging: stem cell therapies.…”
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Optimising Human Mesenchymal Stem Cell Numbers for Clinical Application: A Literature Review by E. Fossett, W. S. Khan

“…Adult mesenchymal stem cells (MSCs) are being investigated further for their use in stem cell therapies. However, as they are found in very low numbers in adult tissue, expansion in vitro is required to produce desired MSC numbers for clinical application. …”
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Ligament-Derived Stem Cells: Identification, Characterisation, and Therapeutic Application by Katie Joanna Lee, Peter David Clegg, Eithne Josephine Comerford, Elizabeth Gail Canty-Laird

“…Ligament is prone to injury and degeneration and has poor healing potential and, with currently ineffective treatment strategies, stem cell therapies may provide an exciting new treatment option. …”
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Trophic Factors from Tissue Stem Cells for Renal Regeneration by Kenji Tsuji, Shinji Kitamura

“…Stem cell therapies against renal injury have been advancing. …”
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The Role of MicroRNAs in Cardiac Stem Cells by Nima Purvis, Andrew Bahn, Rajesh Katare

“…A deeper understanding of the mechanisms by which miRs regulate CSCs may lead to advances in the mode of stem cell therapies for the treatment of cardiovascular diseases.…”
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Comparing Circadian Dynamics in Primary Derived Stem Cells from Different Sources of Human Adult Tissue by Eve H. Rogers, Sandra A. Fawcett, Vanja Pekovic-Vaughan, John A. Hunt

“…The more primitive dental pulp-derived stem cells did not respond as well to the chemical synchronisation but showed temporal clock gene oscillations following rhythmic mechanical stretch, suggesting that incorporating temporal circadian information of different human adult stem cells will have profound implications in optimising tissue engineering approaches and stem cell therapies.…”
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Oligodendrocyte Injury in Multiple Sclerosis. by Mateo Përgjegji, Klei Bame, Ketrina Ceka, Jera Cenalia , Sibora Bërdica , Teona Bushati

“…Emerging therapeutic strategies, such as targeting metabolic pathways, reducing oxidative stress, and enhancing autophagy, have demonstrated potential in preclinical studies. Furthermore, stem cell therapies are being explored for their ability to regenerate oligodendrocytes and restore myelin integrity. …”
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Microtissues in Cardiovascular Medicine: Regenerative Potential Based on a 3D Microenvironment by Julia Günter, Petra Wolint, Annina Bopp, Julia Steiger, Elena Cambria, Simon P. Hoerstrup, Maximilian Y. Emmert

“…However, current stem cell therapies using single-cell suspensions have failed to demonstrate long-lasting efficacy due to the overall low retention rate after cell delivery to the myocardium. …”
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Structural and Functional Characterization of Deceased Donor Stem Cells: A Viable Alternative to Living Donor Stem Cells by Prakash N. Rao, Dayanand D. Deo, Misty A. Marchioni, Rouzbeh R. Taghizadeh, Kyle Cetrulo, Sharyn Sawczak, Jacob Myrick

“…This will offer increased accessibility for patients awaiting stem cell therapies.…”
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Age-Related Yield of Adipose-Derived Stem Cells Bearing the Low-Affinity Nerve Growth Factor Receptor by Raquel Cuevas-Diaz Duran, Maria Teresa González-Garza, Alejandro Cardenas-Lopez, Luis Chavez-Castilla, Delia Elva Cruz-Vega, Jorge E. Moreno-Cuevas

“…Our findings propose CD271+ ADSCs as the primary choice for tissue regeneration and autologous stem cell therapies in older subjects.…”
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The Conditioned Medium of Calcined Tooth Powder Promotes the Osteogenic and Odontogenic Differentiation of Human Dental Pulp Stem Cells via MAPK Signaling Pathways by Jintao Wu, Na Li, Yuan Fan, Yanqiu Wang, Yongchun Gu, Zehan Li, Yin Pan, Gobin Romila, Zuomin Zhou, Jinhua Yu

“…These findings could lead to the creation of stem cell therapies for dental regeneration.…”
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