Effect of BMP-2 Delivery Mode on Osteogenic Differentiation of Stem Cells by Taekhee Jung, John Hwan Lee, Soonjung Park, Yong-Jin Kim, Joseph Seo, Hye-Eun Shim, Ki-Suk Kim, Hyon-Seok Jang, Hyung-Min Chung, Seong-Geun Oh, Sung-Hwan Moon, Sun-Woong Kang

“…The present study highlights the potential value of the tool in stem cell therapy.…”
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The History of Cystinosis: Lessons for Clinical Management by Paul Goodyer

“…Major conceptual break-throughs include (a) its discovery in 1903, (b) recognition of the renal Fanconi syndrome, (c) realization that tissue accumulation of cystine reflects a defective channel in the lysosomal membrane, (d) translation of this discovery to trials of cysteamine, (e) discovery of the CTNS gene, and (f) report of successful stem cell therapy in the cystinotic mouse. This paper focuses on the importance management lessons from these milestones and the potential new therapeutic strategies which may be looming in the near future.…”
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New Strategies and In Vivo Monitoring Methods for Stem Cell-Based Anticancer Therapies by Ping Wang, Aitor Aguirre

“…We also summarize the emerging imaging modalities being applied for monitoring anticancer stem cell therapy success and discuss the implications of these novel technologies for precision medicine.…”
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Retinoic Acid Signal Negatively Regulates Osteo/Odontogenic Differentiation of Dental Pulp Stem Cells by Jiangyi Wang, Guoqing Li, Lei Hu, Fei Yan, Bin Zhao, Xiaoshan Wu, Chunmei Zhang, Jinsong Wang, Juan Du, Songlin Wang

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The Influence of Intervertebral Disc Microenvironment on the Biological Behavior of Engrafted Mesenchymal Stem Cells by Jing Zhang, Wentao Zhang, Tianze Sun, Jinzuo Wang, Ying Li, Jing Liu, Zhonghai Li

“…The emergence of stem cell therapy makes it possible to regenerate and repair degenerated intervertebral disc tissue. …”
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Impacts of stem cells from different sources on wound healing rate in diabetic foot ulcers: a systematic review and meta-analysis by Le Tong, Le Tong, Le Tong, Lin Tang, Lin Tang, Lin Tang, Bangli Tang, Jianna Zhang, Jianna Zhang, Jianna Zhang

“…These findings indicated that stem cell therapy might influence the progression of DFU.…”
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Understanding the multifaceted nature of peptide hydrogels in biomedical research by Srestha Ghosh, Shinjini Chaudhuri, Subhabrata Guha, Gaurav Das

“…In this review, we will present the recent advancements that have occurred in the field of peptide-based hydrogels concerning its biomedical applications especially delivery of targeted delivery, wound healing, tissue engineering, stem cell therapy, etc.…”
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Stem cells in Osteoporosis: From Biology to New Therapeutic Approaches by Vasilis Paspaliaris, George Kolios

“…Safe and predictable pharmaceutical means to increase bone formation have been elusive. Stem cell therapy of osteoporosis, as a therapeutic strategy, offers the promise of an increase in osteoblast differentiation and thus reversing the shift towards bone resorption in osteoporosis. …”
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Cavernous Nerve Injury Resulted Erectile Dysfunction and Regeneration by Nan Jiang, Cheng Wu, Xunrong Zhou, Guanghua Zhai, Jian Wu

“…In addition, such as neuromodulatory proteins, proimmune ligands, gene therapy, stem cell therapy, and the current cutting-edge low-energy shock wave therapy have shown advantages in basic research and limited clinical studies. …”
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Sarcopenia and cachexia: molecular mechanisms and therapeutic interventions by Tiantian Wang, Dong Zhou, Zhen Hong

“…This review discusses the muscle microenvironment's changes contributing to these conditions, recent therapeutic approaches like lifestyle modifications, small molecules, and nutritional interventions, and emerging strategies such as gene editing, stem cell therapy, and gut microbiome modulation. We also address the challenges and opportunities of multimodal interventions, aiming to provide insights into the pathogenesis and molecular mechanisms of sarcopenia and cachexia, ultimately aiding in innovative strategy development and improved treatments.…”
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The Domestic Cat as a Large Animal Model for Characterization of Disease and Therapeutic Intervention in Hereditary Retinal Blindness by Kristina Narfström, Koren Holland Deckman, Marilyn Menotti-Raymond

“…Therapeutic trials have been performed mainly in the former type including stem cell therapy, retinal transplantation, and development of ocular prosthetics. …”
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Mesenchymal Stem Cells: A Potential Therapeutic Approach for Amyotrophic Lateral Sclerosis? by Agnese Gugliandolo, Placido Bramanti, Emanuela Mazzon

“…A cure is not available at this time, and the disease leads to death within 3–5 years, mainly due to respiratory failure. Stem cell therapy is arising as a new promising approach for the treatment of neurodegenerative disorders. …”
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Phases I–III Clinical Trials Using Adult Stem Cells by Ricardo Sanz-Ruiz, Enrique Gutiérrez Ibañes, Adolfo Villa Arranz, María Eugenia Fernández Santos, Pedro L. Sánchez Fernández, Francisco Fernández-Avilés

“…First randomized clinical trials have demonstrated that stem cell therapy can improve cardiac recovery after the acute phase of myocardial ischemia and in patients with chronic ischemic heart disease. …”
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Neuroprotective Effects of Stem Cells in Ischemic Stroke by Weilin Xu, Jingwei Zheng, Liansheng Gao, Tao Li, Jianmin Zhang, Anwen Shao

“…However, it is still lacking of efficient agents. Stem cell therapy, with its vigorous advantages, has attracted researchers around the world. …”
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Procedural Treatments for Knee Osteoarthritis: A Review of Current Injectable Therapies by Lisa M. Billesberger, Kyle M. Fisher, Yawar J. Qadri, Richard L. Boortz-Marx

“…Small studies have examined prolotherapy and stem cell therapy and demonstrate some benefits. Trials involving genicular nerve block procedures have been successful. …”
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Stem Cells in the Treatment of Neuropathic Pain: Research Progress of Mechanism by Meichen Liu, Kai Li, Yunyun Wang, Guoqing Zhao, Jinlan Jiang

“…In this review, we briefly introduce the neuropathic pain, the current treatment strategy, and the development of stem cell therapy, and we collected the experimental and clinical trial articles of many kinds of stem cells in the treatment of neuropathic pain from the past ten years. …”
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Mesenchymal Stem Cells Ameliorate Hyperglycemia in Type I Diabetic Developing Male Rats by Hany N. Yousef, Samia M. Sakr, Sahar A. Sabry

“…One of the most promising treatments for diabetes mellitus (DM) is stem cell therapy. This study is aimed at elucidating the antidiabetic effect of mesenchymal stem cells (MSCs) on streptozotocin- (STZ-) induced DM in developing male rats. …”
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Therapeutic Potential of Mesenchymal Stem Cells in Regenerative Medicine by Devang M. Patel, Jainy Shah, Anand S. Srivastava

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Functional Multipotency of Stem Cells: What Do We Need from Them in the Heart? by Pablo Díez Villanueva, Ricardo Sanz-Ruiz, Alberto Núñez García, María Eugenia Fernández Santos, Pedro L. Sánchez, Francisco Fernández-Avilés

“…Randomized clinical trials have demonstrated that stem cell therapy can improve cardiac recovery after the acute phase of myocardial ischemia and in patients with chronic ischemic heart disease, and several efficacy phase III trials with clinical endpoints are on their way. …”
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Stem Cells for Cardiac Repair: Status, Mechanisms, and New Strategies by Ren Mingliang, Zhang Bo, Wang Zhengguo

“…But many clinical trials have shown that the stem cell therapy of heart failure is modest or not effective. …”
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