Synthesis of novel titania nanoparticles using corn silky hair fibres and their role in developing a smart restorative material in dentistry by Afsheen Mansoor, Emaan Mansoor, Ezza Mansoor, Efrah Mansoor, Atta Ullah Shah, Uzma Asjid, João Filipe Brochado Martins, Sami Ullah Khan, Paulo J. Palma

“…Adding 5 % of these smart titania nanoparticles to GIC resulted in a substantial increase in its shear bond strength to enamel, which rose to 4.93 + 0.74 MPa, with a standard error of 0.23, and this change was statistically significant at p < 0.05. The material's sustainable surface characteristics were confirmed by the presence of increased Fluorine (6.46 %) and Titanium (0.79 %) alongside a decrease in the amounts of Aluminium (23.51 %), Silicon (20.01 %), Phosphorus (0.33 %), and Sulphur (0.09 %), as indicated by spectral mapping. …”
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Sex-related association between smoke exposure and gallstones in a US population: a cross-sectional study by Xingyong Huang, Xuanyu Hao, Tingting Wang, Xiaoyue Zhang, Peng Wu, Lufan Shen, Yuanyuan Yang, Wanchuan Zhang, Kai Zhang

“…However, the association was statistically insignificant in men. The subgroup analysis showed the robustness of the association. …”
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Role of Chest X-Ray in Coronavirus Disease and Correlation of Radiological Features with Clinical Outcomes in Indian Patients by Satyanand Sathi, Richa Tiwari, Savita Verma, Anil Kumar Garg, Virendra Singh Saini, Manoj Kumar Singh, Amit Mittal, Devinder Vohra

“…The mean ± standard deviation (SD) and frequency (%) were determined, and an unpaired t test, Spearman’s rank correlation coefficient, and logistic regression analyses were performed for statistical analyses. Among 120 COVID-19 patients, 74 (61.67%) and 46 (38.33%) were males and females, respectively; 64 patients (53.33%) had ground-glass opacities (GGO), 55 (45.83%) had consolidation, and 38 (31.67%) had reticular-nodular opacities, with lower zone distribution (50%) and peripheral distribution (41.67%). …”
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Immunogenetics of longevity and its association with human endogenous retrovirus K by Lisa M. James, Lisa M. James, Lisa M. James, Apostolos P. Georgopoulos, Apostolos P. Georgopoulos, Apostolos P. Georgopoulos, Apostolos P. Georgopoulos

“…Next, we performed a stepwise multiple linear regression where the age of the participant was the dependent variable and the 13 median predicted HLA-virus binding affinities were the independent variables.ResultsThe analyses yielded only one statistically significant effect–namely, a positive association between age and HERVK (P = 0.005). …”
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Anticholinergic burden and behavioral and psychological symptoms in older patients with cognitive impairment by Sabrina Pistorio, Gianluca Scotto di Tella, Vittoria Canzanella, Raffaella Merenda, Gianluigi Cuomo, Paola Iacotucci, Vincenzo Carnovale, Leonardo Bencivenga, Maria Vargas, Annalaura Manes, Mauro Cataldi, Giuseppe Rengo, Giuseppe Rengo, Michela Zanetti, Grazia Daniela Femminella, Grazia Daniela Femminella

“…A multiple linear regression was performed to identify factors associated with higher NPI score and a logistic regression model was built to identify drug classes associated with ACB ≥ 3.ResultA total of 173 patients (mean age 74 ± 7, 74 men) were included in the study; 132 patients with ACB &lt; 3 (low risk) versus 41 patients with ACB ≥3 (high risk) were compared. No statistically significant differences were found between the two groups in terms of demographics (age, sex) and anamnestic variables (education, marital status, family history of dementia, hypertension, diabetes, smoking, dyslipidemia, atrial fibrillation, coronary heart disease and use of alcohol). …”
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PIK3CA mutational status in tissue and plasma as a prognostic biomarker in HR+/HER2− breast cancer by Eduardo Terán, Rebeca Lozano, César A. Rodríguez, Mar Abad, Luis Figuero, José Antonio Muñoz, Belén Cigarral, Aline Rodrígues, Magdalena Sancho, M. Asunción Gómez, Daniel Morchón, Juan Carlos Montero, José María Sayagués, M. Dolores Ludeña, Emilio Fonseca

“…A subanalysis was carried out based on exons 9 and 20, which showed a statistically poorer PFS in PIK3CAm exon 9 versus 20 population (9.7 m vs. 30.3 m; HR = 2.84; p = 0.024). …”
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The Performance of Equations That Estimate Glomerular Filtration Rate against Measured Urinary Creatinine Clearance in Critically Ill Patients by Hasan M. Al-Dorzi, Abdulmajeed A. Alsadhan, Ayman S. Almozaini, Ali M Alamri, Hani Tamim, Musharraf Sadat, Lolowa Al-Swaidan, Elwaleed Elhassan, Yaseen M. Arabi

“…The correlations between the different equations and CrCl24h-urine were modest (r: 0.62 to 0.79; p<0.0001). Bias was statistically significant for CGactual-wt (21 ml/min), CGadjusted-wt (12 ml/min), and MDRD-6 (-10 ml/min) equations. …”
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In-Season Automated Mapping of Xinjiang Cotton Based on Cumulative Spectral and Phenological Characteristics by Yongsheng Huang, Yaozhong Pan, Yu Zhu, Xiufang Zhu, Xingsheng Xia, Qiong Chen, Jufang Hu, Hongyan Che, Xuechang Zheng, Lingang Wang

“…The CSP method was applied to 10 major cotton-producing counties in Xinjiang, and the MRE between the CSP-detected area and the statistical area was 14.1&#x0025;. Further analysis revealed that the CSP index can accurately and effectively distinguish cotton from other features and contemporaneous crops and that the Otsu&#x2013;Sauvola automatic threshold method has robustness and regional consistency, thus providing an automatic and effective method for large-scale mapping of cotton in the early growing season.…”
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Chinese herbal formula Tongxie Yaofang granules for diarrhoea-predominant irritable bowel syndrome: a randomised, double-blind, placebo-controlled, phase II trial by Nicola Robinson, Mei Han, Ling Yan, Vincent Chi Ho Chung, Jian-Ping Liu, Hui-Juan Cao, Shi-Bing Liang, Hong-Jie Cheng, Qiao-Yan Zhang, Yu-Fei Li, Ze-Yu Yu, Ling-Yao Kong, Yan-Mei Cai, Li-Bao An, Bao-Tuan Zhao, Shan-Shan Xu, Nai-Wei Zhang, Bo-Yi Jia, Wei-Fang Liu, Fang Niu, Ba-Teer Wu, Jin-Ming Song, Shu-Xin Jia, Meng-Meng Shi, Xiao-Na Zhang

“…Both groups had a high and similar rate of symptom reduction (79.2% (38/48) vs 70.8% (34/48)). There were no statistically significant differences between the two groups on secondary outcomes, although both groups showed substantial improvements. …”
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Low-activity [18F]-somatostatin receptor (SSTR) imaging using [18F]SiTATE on a long axial field-of-view PET/CT scanner by Nils F. Trautwein, Eduardo Calderón, Pia M. Linder, Gerald Reischl, Philippe Driessen, Wenhong Lan, Andreas S. Brendlin, Thorben Groß, Helmut Dittmann, Martina Hinterleitner, Christian la Fougère, Fabian P. Schmidt, Lena S. Kiefer

“…Conclusion Reducing the administered activity of injected [18F]SiTATE by 66% to 1 MBq/kg (HS & UHS) is feasible in a LAFOV PET/CT scanner, maintaining clinically diagnostic image quality without statistically significant deviations in PET uptake parameters and MTV. …”
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Comparison of objectively measured and estimated cardiorespiratory fitness to predict all-cause and cardiovascular disease mortality in adults: A systematic review and meta-analysi... by Ben Singh, Cristina Cadenas-Sanchez, Bruno G.G. da Costa, José Castro-Piñero, Jean-Philippe Chaput, Magdalena Cuenca-García, Carol Maher, Nuria Marín-Jiménez, Ryan McGrath, Pablo Molina-García, Jonathan Myers, Bethany Gower, Francisco B. Ortega, Justin J. Lang, Grant R. Tomkinson

“…For both all-cause and CVD mortality, there were no statistically significant differences in RR per higher MET between objectively measured (RR range: 0.86–0.90) and maximal exercise-estimated (RR range: 0.85–0.86), submaximal exercise-estimated (RR range: 0.91–0.94), and non-exercise-estimated CRF (RR range: 0.81–0.85). …”
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Resting-state functional brain connectivity in female adolescents with first-onset anorexia nervosa by Katrien F.M. Bracké, Laura Monteiro Rente Dias, Marisha N. Meijer, Cathelijne P.M. Steegers, Laurinde F. den Heijer, Tess van der Harst, Marjolein H.G. Dremmen, Meike W. Vernooij, Gwen C. Dieleman, Tonya White

“…Linear regression analyses were conducted to assess differences in RS-FC between AN and TD participants, as well as to assess whether RS-FC was associated with clinical symptoms at baseline and at one-year of follow-up. Two statistical models were used: model 1 adjusted for age and socioeconomic status (SES), and model 2 additionally adjusted for baseline anxiety and depressive symptoms. …”
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Rewilding beech-dominated temperate forest ecosystems: effects on carbon stocks and biodiversity indicators by Markuljaková K, Mikoláš M, Svitok M, Meigs GW, Keeton WS, Kozák D, Pavlin J, Gloor R, Kalaš M, Ferenčík M, Ralhan D, Frankovič M, Hofmeister J, Dúhová D, Mejstrík M, Dušátko M, Veber A, Knír T, Svoboda M

“…We compared some of the best-preserved primary old-growth forests with adjacent secondary old-growth forests which have been allowed to undergo self-development for an extended period of seven decades in the ecologically and socially important beech-dominated forests of the Carpathian Mountains. Statistical analysis showed no significant differences in carbon stock and structural biodiversity indicators between the two forest categories. …”
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Double-Blind Clinical Trial of Arginine Supplementation in the Treatment of Adult Patients with Sickle Cell Anaemia by Renata M. N. Eleutério, Francisco O. Nascimento, Tamara G. Araújo, Marilena F. Castro, Tarcísio P. Almeida Filho, Pedro A. Maia Filho, José Eleutério, Darcielle B. D. Elias, Romélia P. G. Lemes

“…The main outcome measures were nitrite and pain. Results. Statistical analysis showed that the levels of NO were increased in the study group, and there was also a reduction in pain frequency using a pain frequency scale by day, week, and month. …”
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Associations between Children’s Exposure to PM2.5 and their Serum Inflammatory Responses in Taiwan by Wei-Jung Tseng, Jian-He Lu, How-Ran Chao, Ming-Hsien Tsai, Yu-Ting Chang, Liang-Jen Wang, Chih-Cheng Chen, Wan-Nurdiyana-Wan Mansor, Juliana Jalaludin, Chih-Lung Wang, Ying-I Tsai

“…Children’s serum TNF-α was significantly linked to PM2.5 exposure scenarios (p = 0.031) by the test of the multivariate analysis (adjusted R2 = 0.033, p = 0.039), but the other variables of age (p = 0.147) and gender (p = 0.291) were not statistically significant. In conclusion, serum TNF-α might be positively and significantly correlated with the longitudinal exposure of schoolchildren to PM2.5, especially among children living in TRAP-PM2.5 region.…”
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Work-related burnout and its associated factors among kindergarten teachers: a multi-center cross-sectional study in Ethiopia by Anmut Endalkachew Bezie, Girum Tareke Zewude, Amensisa Hailu Tesfaye, Amensisa Hailu Tesfaye, Asmare Asrat Yirdaw, Alebachew Bitew Abie, Giziew Abere

“…Variables found significant in the bivariable analysis were then exported into a multivariable logistic regression model to identify statistically significant variables at a p value &lt; 0.05 and a 95% confidence interval.ResultsThe response rate was 95% (401/422). 97.5% of the participants were female, and the participants’ mean (standard deviation) age was 28.5 years (SD ± 5.8). …”
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Plasma EphA2 level is a superior biomarker to Del-1 for sepsis diagnosis and prognosis by Eun Hye Lee, Mi Hwa Shin, Se Hyun Kwak, Ji Soo Choi, Ah Young Leem, Su Hwan Lee, Kyung Soo Chung, Young Sam Kim, Sang-Guk Lee, Moo Suk Park

“…The levels of both biomarkers were higher in 28-day non-survivors than in survivors, in patients with sepsis (EphA2:898.09 vs. 475.88 pg/mL, p &lt; 0.001; Del-1:46.09 vs. 32.68 pg/mL, p = 0.193); however, only EphA2 was statistically significant. The area under the curve for the EphA2 was 0.74 in the receiver operating characteristic curve analysis for predicting 28-day mortality, whereas APACHE II, SOFA, and Del-1 showed values of 0.762, 0.614, and 0.595, respectively. …”
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Oxidative balance score was negatively associated with the risk of metabolic syndrome, metabolic syndrome severity, and all-cause mortality of patients with metabolic syndrome by Zhixiao Xu, Xiong Lei, Weiwei Chu, Luoqi Weng, Chengshui Chen, Chengshui Chen, Chengshui Chen, Ran Ye

“…These associations retained their strength even subsequent to the introduction of sensitivity analyses. There existed a statistically significant negative correlation between diet/lifestyle OBS and both MetS risk as well as MetS severity.ConclusionsAn inverse correlation was observed between OBS and the susceptibility to MetS, MetS severity, and all-cause mortality of MetS patients. …”
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Russian Non-Interventional Study of the Efficacy and Tolerability of Rifaximin-α Therapy in Patients with Uncomplicated Diverticular Disease under the Conditions of Outpatient Prac... by O. S. Shifrin, E. A. Poluektova, A. V. Korolev, T. I. Semenova, M. V. Shein, G. N. Leksikova, O. A. Tokareva, O. E. Davydova, P. S. Andreev, S. E. Katorkin, A. A. Chernov, A. V. Zhuravlev, O. S. Sek, A. A. Kopina, N. Yu. Samokhina, Yu. V. Gorozhankina, M. F. Samigullin, V. S. Groshilin, E. N. Borisova, T. A. Petrova, I. Yu. Pirogova, S. V. Mednikov, N. V. Smagin, A. S. Sarsenbaeva, N. V. Smirnova, L. G. Kirsanova, N. M. Malyutina, M. A. Smirnova, E. N. Shleikova, V. T. Ivashkin

“…The total score of symptom intensity decreased from 5.6 at the inclusion visit, to 2.2 points at the second visit and to 0.9 points at the end of the observation. A statistically significant (p &lt;0.05) positive dynamics was observed in relation to all evaluated symptoms (abdominal pain, constipation, diarrhea, flatulence, tenesmus). …”
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Land use variation impacts on trace elements in the tissues and health risks of a commercial fish by N.D. Takarina, O.M. Chuan, T.G. Pin, I. Femnisya, A. Fathinah, A.N.B. Ramadhan, R. Hermawan, A. Adiwibowo

“…Differences and correlation of heavy metal data in each tissue and location were statistically analyzed using Pearson correlation values (r), Analysis of Variance, and x2-test. …”
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