Combination of the endoscopic septonasal flap technique and bioabsorbable steroid-eluting stents for repair of congenital choanal atresia in neonates and infants: a retrospective s... by Peng-peng Wang, Li-xing Tang, Jie Zhang, Xiao-jian Yang, Wei Zhang, Yang Han, Xiao Xiao, Xin Ni, Wen-tong Ge

“…Compared with the silicone stents group, the average operative duration and the hospital length of stay in the bioabsorbable steroid-eluting stents group were decreased [(97.46 ± 15.37) min vs (83.49 ± 19.16) min t = 13.733, P < 0.001] [(12.8 ± 3.22) d vs (7.67 ± 3.91) d t = 15.082, P < 0.001], the average number of procedures was reduced [(2.04 ± 0.64) vs (1.00 ± 0.001), t = 82.689, P < 0.001], the differences were statistically significant. There were no reports of postoperative restenosis and complications in the bioabsorbable steroid-eluting stents group, and follow-up endoscopic examinations showed patency and stable nasal passages in all cases. …”
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Middle Cerebral Artery Pulsatility Index for Prediction of Successful Induction of Labour in Postdated Pregnancy: A Prospective Observational Study by Yashi Nagar, Rekha Bharti, Kajal Baleja, Amita Malik, Divya Pandey, Jyotsna Suri

“…A p-value of <0.05 was considered statistically significant. Results: Out of 296 women enrolled in the study, 285 women (96.3%) had successful IOL. …”
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Impact of EML4‐ALK Variants and TP53 Status on the Efficacy of ALK Inhibitors in Patients With Non‐small Cell Lung Cancer by Zihua Zou, Lige Wu, Xuezhi Hao, Yan Li, Li Liang, Yangchun Gu, Jianming Ying, Junling Li, Puyuan Xing

“…Methods This was a retrospective cohort study, wherein patients diagnosed with locally advanced or metastatic non‐small cell lung cancer harboring EML4‐ALK fusion were stratified into two cohorts based on their first‐line treatment: Cohort 1 received alectinib, while Cohort 2 received crizotinib. Statistical analysis was employed to investigate the impact of different EML4‐ALK variants and TP53 status on the efficacy of first‐line ALK‐TKIs. …”
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Accuracy of artificial intelligence algorithms in predicting acute respiratory distress syndrome: a systematic review and meta-analysis by Yaxin Xiong, Yuan Gao, Yucheng Qi, Yingfei Zhi, Jia Xu, Kuo Wang, Qiuyue Yang, Changsong Wang, Mingyan Zhao, Xianglin Meng

“…The retrieved literature was screened according to inclusion and exclusion criteria, the quality of the included studies was assessed using QUADAS-2, and the included studies were statistically analyzed. Results Among the 2, 996 studies, 33 were included in this meta-analysis, which showed that the pooled sensitivity of AI in predicting ARDS was 0.81 (0.76–0.85), the pooled specificity was 0.88 (0.84–0.91), and the area under the receiver operating characteristic curve (AUC) was 0.91 (0.88–0.93). …”
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Long non-coding RNA Malat1 modulates CXCR4 expression to regulate the interaction between induced neural stem cells and microglia following closed head injury by Qin Dong, Pengyu Chen, Wenqiao Qiu, Zhijun Yang, Yanteng Li, Yuhui Zhou, Lili Guo, Dan Zou, Ruxiang Xu, Mou Gao

“…Student’s t-test and one-way analysis of variance (ANOVA) with Tukey’s post hoc test were used to determine statistical significance. Results Our results indicated that Malat1 could act as a sponge of miR-139-5p to modulate the expression of CXCR4 that exerted significant influence on the immunoregulatory effects of iNSCs on the secretion of CXCL12, TNF-α and IGF-1 by activated microglia. …”
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A U-shaped non-linear association between serum uric acid levels and the risk of Hashimoto’s thyroiditis: a cross-sectional study by Manli Yan, Wenhua Shi, Ping Gong, Yunsi Xie, Kaiyuan Zhang, Xiang Li, Hua Wei, Hua Wei

“…Significant differences were observed in metabolic indicators, including serum uric acid (SUA), serum creatinine (SCr), albumin (ALB) and high-density lipoprotein cholesterol (HDL-C), between the two groups, with statistical significance. A binary logistic regression model was established, revealing that SCr had a significant impact in both univariate and multivariate analyses. …”
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A systematic review and meta-analysis of the impact of transcranial direct current stimulation on cognitive function in older adults with cognitive impairments: the influence of do... by Thatchaya Prathum, Thanwarat Chantanachai, Oranich Vimolratana, Chotica Laksanaphuk, Irin Apiworajirawit, Benchaporn Aneksan, Kanthika Latthirun, Cheng-Ta Yang, Wanalee Klomjai

“…AD was diagnosed based on the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV), or the National Institute of Neurological and Communicative Disorders and Stroke – Alzheimer’ Disease and Related Disorders Association (NINCDS-ADRDA) criteria. …”
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Whether the Indications for Reverse Shoulder Arthroplasty Should Continue to Be Expanded? A Systematic Review and Meta‐Analysis by Huankun Li, Hangsheng Bao, Zhidong Yang, Baijun Hu, Yaocheng Pan, Yi Wang, Jiayi Chen, Hongjun Chen, Bisheng Shen, Yonggen Zou

“…In terms of complication and revision rates, RTSA had lower rates compared to HA and ATSA, except for the complication rate, where there was no significant difference between RTSA and ATSA (p = 0.521), but statistically significant differences were observed in other measures. …”
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Treatment time and learning curve analysis of 1.5 T MR-Linac workflows led by radiation oncologists or therapists by J.M. Westerhoff, F.J. Raaijmakers, L.A. Daamen, E.N. de Groot-van Breugel, L.T.C. Meijers, J.R.N. van der Voort van Zyp, J.J.C. Verhoeff, S. Mook, H.M. Verkooijen, M.P.W. Intven

“…A p-value < 0.01 was considered statistically significant. Results: In total, 4942 fractions of 645 patients were included. …”
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Impacts of drought on respiratory mortality in the upper midwest United States: a population subgroup assessment by Yeongjin Gwon, Yuanyuan Ji, Jesse D Berman, Azar M Abadi, Ronald D Leeper, Jared Rennie, Jesse E Bell

“…Stratification analyses were conducted by age group, gender, race, urbanicity, and state within the region. Statistically significant associations were identified between respiratory mortality and the severe droughts. …”
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Age-related differences in long-term potentiation-like plasticity and short-latency afferent inhibition and their association with cognitive function by Tong Wang, Ying Shen, Tianjiao Zhang, Chuan He, Qian Lu, Jie Song, Manyu Dong, Yilun Qian, Sisi Huang, Jing Teng

“…Furthermore, after employing the Bonferroni correction, the correlation analysis revealed that only the positive correlation between LTP-like plasticity and language function (r=0.61, p&lt;0.001) in the younger group remained statistically significant.Conclusions During the normal ageing process, a decline in synaptic plasticity may precede cholinergic system dysfunction. …”
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Comparative analysis of dominant gut microbiota in Inflammatory Bowel Disease patients and healthy individuals: A case-control study by Alireza Ahmadi, Ebrahim Kouhsari, Shabnam Razavi, Nima Mohamadzadeh, Sima Besharat, Mohammad Ali Vakili, Taghi Amiriani

“…While some bacterial groups exhibited trends toward higher abundance in either CD or UC patients, these differences were not statistically significant (p-value >0.111). The correlation matrix analysis revealed specific co-occurrence patterns: Bacteroides showed a strong negative correlation with Prevotella, more abundant in healthy controls, suggesting a shift in dominance in IBD patients. …”
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A novel model-based meta-analysis to indirectly estimate the comparative efficacy of two medications: an example using DPP-4 inhibitors, sitagliptin and linagliptin, in treatment o... by Yan Gong, James Rogers, Christian Friedrich, Sanjay Patel, Alexander Staab, Jorge Luiz Gross, Daniel Polhamus, William Gillespie, Brigitta Ursula Monz, Silke Retlich

“…Objectives To develop a longitudinal statistical model to indirectly estimate the comparative efficacies of two drugs, using model-based meta-analysis (MBMA). …”
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A case-matched series comparing functional outcomes for robotic-assisted unicompartmental knee arthroplasty versus functionally aligned robotic-assisted total knee arthroplasty by Jonathan R. Manara, Macdaniel Nixon, Beth Tippett, Wil Pretty, Dermot Collopy, Gavin W. Clark

“…There were no differences seen in FJS or OKS at one year postoperatively. There were no statistically significant differences between the groups at 24 months in all the variables assessed. …”
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Effect of trilaciclib administered before chemotherapy in patients with extensive-stage small-cell lung cancer: A pooled analysis of four randomized studies by Ying Liu, Lin Wu, Dingzhi Huang, Qiming Wang, Chen Yang, Li Zhou, Shuguang Sun, Xiaomei Jiang, Ying Cheng

“…Trilaciclib demonstrated a clinically and statistically significant reduction in DSN in cycle 1 and in the incidence of SN and febrile neutropenia (FN) in the overall, 1 L, 2 L/3 L populations. …”
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Acceptance of multiple micronutrient supplementations (MMS) and iron and folic acid supplement utilisation among pregnant and lactating women in the rural part of Ethiopia, 2022: a... by Zewdie Birhanu, Menen Tsegaw, Stanley Chitekwe, Ramadhani Noor, Rachana Sharma, Finina Abebe, Yordanos Tadesse Kidanemariam, Ahmednasir Abdi, Hiwot Getachew, Asli Hassan Aden, Tesfaye Chuko, Tariku Dejene, Ahmed Mohammed Dawd

“…Both bivariable and multivariable logistic regression analysis was conducted with a p value&lt;0.05, and a 95% CI was considered statistically significant. Qualitative data were coded and analysed thematically.Participants A total of 410 pregnant and lactating women.Results The overall level of iron-folic acid utilisation was 59.3%. …”
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The Protocol for the Multi-Ethnic, multi-centre raNdomised controlled trial of a low-energy Diet for improving functional status in heart failure with Preserved ejection fraction (... by Noelle Robertson, Melanie J Davies, Thomas Yates, Gerry P McCann, Gaurav Singh Gulsin, Emer M Brady, Joanne V Wormleighton, Eylem Levelt, Oliver Rider, Jiliu Pan, Christopher Miller, Iain Squire, Mehak Asad, Fardad Soltani, Michelle Hadjiconstantinou, Rachel L Brown, Joanna M Bilak

“…Optional substudies include a qualitative study assessing participants’ experiences and barriers to adopting MRP, and skeletal muscle imaging and cardiac energetics using 31Phosphorus MR spectroscopy.Statistical analysis Complete case analysis will be conducted with adjustment for baseline randomisation factors including sex, ethnicity and baseline SGLT2-i use. …”
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Machine learning prediction of anxiety symptoms in social anxiety disorder: utilizing multimodal data from virtual reality sessions by Jin-Hyun Park, Yu-Bin Shin, Dooyoung Jung, Ji-Won Hur, Seung Pil Pack, Heon-Jeong Lee, Hwamin Lee, Chul-Hyun Cho, Chul-Hyun Cho

“…This study employed extended Geneva minimalistic acoustic parameter set for acoustic feature extraction and extracted statistical attributes from time series-based physiological responses. …”
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Exploring Dance as a Therapeutic Approach for Parkinson Disease Through the Social Robotics for Active and Healthy Ageing (SI-Robotics): Results From a Technical Feasibility Study by Roberta Bevilacqua, Elvira Maranesi, Marco Benadduci, Gabriella Cortellessa, Alessandro Umbrico, Francesca Fracasso, Giovanni Melone, Arianna Margaritini, Angela La Forgia, Pierpaolo Di Bitonto, Ada Potenza, Laura Fiorini, Carlo La Viola, Filippo Cavallo, Alessandro Leone, Andrea Caroppo, Gabriele Rescio, Mauro Marzorati, Amedeo Cesta, Giuseppe Pelliccioni, Giovanni Renato Riccardi, Lorena Rossi

“…To stimulate engagement, sessions were organized in the shape of exergames where an avatar shows patients the movements they should perform to correctly carry out a dance-based rehabilitation exercise. ResultsStatistical analysis reveals a significant difference on the Performance-Oriented Mobility Assessment scale, both on balance and gait aspects, together with improvements in Short Physical Performance Battery, Unified Parkinson Disease Rating Scale–III, and Timed Up and Go test, underlying the usefulness of the rehabilitation intervention on the motor symptoms of PD. …”
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Patient satisfaction with radio-frequency identification (RFID) tag localization compared with wire localization for nonpalpable breast lesions: the RFID trial by Raphaël Pete, Céleste Pinard, Fanny Sirodot, Ioana Molnar, Margot Dressaire, Angeline Ginzac, Catherine Abrial, Xavier Durando, Marielle Tekath

“…Conclusion Our results show a statistically significant difference in median patient satisfaction score with the localization of non-palpable breast cancer lesions using RFID tags compared to the use of the WL. …”
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