Fecal Microbiota Transplantation as Therapy for Treatment of Active Ulcerative Colitis: A Systematic Review and Meta-Analysis by Xiaolei Liu, Yan Li, Kaichun Wu, Yongquan Shi, Min Chen

“…FMT with pooled donor stool (RR=0.69, 95% CI 0.56-0.85) and higher frequency of administration (RR=0.76, 95% CI 0.62-0.93) may be more effective with regard to clinical remission. There was no statistically significant difference in serious adverse events with FMT compared with controls (RR=0.98, 95% CI 0.93-1.03). …”
Get full text

Role of the serum levels of the inter-organs messenger fibroblast growth factor 21 (FGF21) in the diagnosis and prognosis of breast cancer patients by Stella Maris Ranuncolo, Eduardo Armanasco, Myriam Nuñez, Laura Yuan, Sujhrob Makhkamov, Mariana S. De Lorenzo

“…We did not find any significant association between the serum FGF21 levels, and many clinical-pathological or metabolic parameters determined at the diagnosis of the primary disease. Interestingly, a statistically significant correlation was determined between serum FGF21 and the body mass index (BMI). …”
Get full text

Quantification of Myocardial Biomarkers in Sudden Cardiac Deaths Using a Rapid Immunofluorescence Method for Simultaneous Biomarker Analysis by Matteo Antonio Sacco, Valerio Riccardo Aquila, Saverio Gualtieri, Roberto Raffaele, Maria Cristina Verrina, Lucia Tarda, Santo Gratteri, Isabella Aquila

“…Results: The study identified statistically significant differences in myoglobin and TnI levels between the SCD group and the control group, though myoglobin’s diagnostic reliability remains limited due to its lack of specificity for myocardial injury. …”
Get full text

Surface water and flood-based agricultural systems: Mapping and modelling long-term variability in the Senegal river floodplain by Andrew Ogilvie, Cheickh Sadibou Fall, Ansoumana Bodian, Didier Martin, Laurent Bruckmann, Djiby Dia, Issa Leye, Papa Malick Ndiaye, Donissongou Dimitri Soro, Jean Homian Danumah, Jean-Claude Bader, Jean-Christophe Poussin

“…Validated against ground truth data, the approach is upscaled using cloud computing across this 2250 km2 floodplain over 1999–2022. Statistical regression models are then developed to estimate flooded and cultivated areas based on upstream flow values since 1950 and analyse trends and exceedance probabilities over time. …”
Get full text

Deep immunophenotyping of circulating immune cells in major depressive disorder patients reveals immune correlates of clinical course and treatment response by Fabiola Stolfi, Claudio Brasso, Davide Raineri, Virginia Landra, Camilla Barbero Mazzucca, Ali Ghazanfar, Lorenza Scotti, Riccardo Sinella, Vincenzo Villari, Giuseppe Cappellano, Paola Rocca, Annalisa Chiocchetti

“…The diagnosis of MDD remains clinical, based on the Diagnostic and Statistical Manual of Mental Disorders (DSM)-5 criteria, as biomarkers have not yet been validated for diagnostic purposes or as predictors of treatment response. …”
Get full text

Effects of ambient air pollutants on cardiovascular disease hospitalization admission by L. Salvaraji, R. Avoi, M.S. Jeffree, S. Saupin, H.R. Toha, S.B. Shamsudin

“…Collected data were analysed spatially and statistically. Autoregressive integrated moving average modelling was implemented to forecast the cardiovascular disease hospital admission.FINDING: Kota Kinabalu recorded the highest hospital admissions for cardiovascular disease, followed by Sandakan, Tawau and Keningau. …”
Get full text

Long-term outcome of photodynamic therapy with hexyl aminolevulinate, 5-aminolevulinic acid nanoemulsion and methyl aminolevulinate for low-risk Basal Cell Carcinomas by M. Salmivuori, M. Grönroos, T. Tani, J. Räsänen, E. Snellman, N. Neittaanmäki

“…Results: According to intention-to-treat (ITT) analyses, the cumulative response rate at one year was 90.6 % for MAL, 81.3 % for BF-200 ALA, and 75.8 % for HAL, and correspondingly at five years 71.9 %, 54.6 % and 60.6 %. There were no statistically significant differences between interventions and comparator. …”
Get full text

Epicardial Fat Tissue: A Potential Marker for Coronary Microvascular Dysfunction by Waiel Abusnina, Ilan Merdler, Matteo Cellamare, Kalyan R. Chitturi, Abhishek Chaturvedi, Irwin M. Feuerstein, Cheng Zhang, Sevket Tolga Ozturk, Teshome Deksissa, Vaishnavi Sawant, Kassandra Lopez, Lior Lupu, Dan Haberman, Itsik Ben‐Dor, Lowell F. Satler, Ron Waksman, Hayder D. Hashim, Brian C. Case

“…Univariate regression analysis demonstrated a statistically significant association between EFV index and CMD diagnosis (odds ratio, 1.037 [95% CI, 1.014–1.063]; P=0.003), while no significance was observed for EFV (odds ratio, 1.006 [95% CI, 0.995–1.017]; P=0.292). …”
Get full text

Endothelial Activation and Stress Index (EASIX) to predict mortality after allogeneic stem cell transplantation: a prospective study by Axel Benner, Peter Dreger, Grzegorz W Basak, Christian Koenecke, Olaf Penack, Christophe Peczynski, Lucia López Corral, Ivan Moiseev, Hélène Schoemans, Zinaida Peric, Thomas Luft, Simona Sica, Mutlu Arat, Maija Itäla-Remes, Nicolaas P M Schaap, Michal Karas, Ludek Raida, Thomas Schroeder, Elisabetta Metafuni, Tulay Ozcelik, Brenda M Sandmaier, Lambros Kordelas

“…We were able to validate the cut-off and found that EASIX ≥3 was associated with more than twofold increased risk for NRM in multivariate analysis (HR=2.18, 95% CI 1.2 to 3.94; p=0.01). No statistically significant difference could be observed for the incidence of relapse.Conclusions The results of this study provide a prospectively validated standard laboratory biomarker index to estimate the transplant-related mortality risk after alloSCT. …”
Get full text

Efficacy of Antimicrobial Photodynamic Therapy for Treating Moderate to Deep Periodontal Pockets in Individuals with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis by João Victor Soares Rodrigues, Mariella Boaretti Deroide, Wilton Mitsunari Takeshita, Valdir Gouveia Garcia, Rafael Scaf de Molon, Leticia Helena Theodoro

“…Forest plots for PD, BOP, PI, and CAL at baseline, three months, and six months revealed no statistically significant differences between the SI+aPDT group and the SI-only group. …”
Get full text

Enhancing furcation involvement classification on panoramic radiographs with vision transformers by Xuan Zhang, Enting Guo, Xu Liu, Hong Zhao, Jie Yang, Wen Li, Wenlei Wu, Weibin Sun

“…ViT also recorded the highest area under the curve (AUC) (98%), outperforming the other models with statistically significant differences (p < 0.05), confirming its enhanced classification capability. …”
Get full text

Predictive factors of thrombosis during autologous stem cell transplantation in multiple myeloma: Experience from EHU Oran (Algeria) by Mohammed Amine BEKADJA, Brahim BENZINEB, Mansour BELKACEM, Hafida OUDJERIOUAT, Badra ENTASOLTAN, Soufi OSMANI, Kamila AMANI, Samira BOUCHAMA, Leila CHAREF, Mohamed BRAHIMI, Abdessamad ARABI, Rachir Amar BOUHASS, Nabil YAFOUR

“…Thepredictive factors studied are: age, co-morbidities, use of IMiDs, use of Granocyte colony stimualing factor in mobilization, the central venous catheter insertion site, cytapheresis count, CD34+ perfused, and finally deep venous thrombosis prophylaxis by a low molecular weight heparin .The statistical analysis focused on a univariate study, followed by a multivariate analysis using binary logistic regression. …”
Get full text

Identification of Resistance to Bacterial Blight in Introgression Lines of Yuanjiang Common Wild Rice and Analysis of Its Japonica Indica Properties by Wang KAN, Hesheng YANG, Huanzhi MENG, Jiyun ZHOU, Zaiquan CHENG, Yun ZHANG, Suqin XIAO, Li LIU, Bo WANG, Fuyou YIN, Qiaofang ZHONG, Jinlu LI, Dunyu ZHANG, Ling CHEN

“…The correlation between these two traits was discussed by statistical analysis.【Result】The results of japonica and indica property analysis showed that among 280 introgression lines, indica rice types were dominant, with a total of 218 samples, while japonica rice types had 61 samples, and the japonica and indica properties of another one could not clearly be distinguished. …”
Get full text

Profiles of Killer Systems and Volatile Organic Compounds of Rowanberry and Rosehip-Inhabiting Yeasts Substantiate Implications for Biocontrol by Iglė Vepštaitė-Monstavičė, Juliana Lukša-Žebelovič, Violeta Apšegaitė, Raimondas Mozūraitis, Robertas Lisicinas, Ramunė Stanevičienė, Laima Blažytė-Čereškienė, Saulius Serva, Elena Servienė

“…It was revealed that the patterns of emitted volatiles are yeast species-specific. Statistically significant differences between the individual VOCs were observed among killing phenotype-possessing vs. non-killer <i>S. paradoxus</i> yeasts, thus revealing the involvement of killer systems in multi-level biocontrol enablement. …”
Get full text

Quasi-weekly oscillation of regional PM_2.5 transport over China driven by the synoptic-scale disturbance of the East Asian winter monsoon circulation by Y. Bai, T. Zhao, K. Meng, Y. Zhou, J. Xiong, X. Sun, L. Shen, Y. Yue, Y. Zhu, W. Hu, J. Yao

“…By constructing the data of daily PM<span class="inline-formula">_2.5</span> transport flux in CEC in the winters of 2015–2019, we utilize the extended empirical orthogonal function (EEOF) decomposition and other statistical methods to extract the moving spatial distribution of regional PM<span class="inline-formula">_2.5</span> transport over CEC, recognizing the QWO in regional PM<span class="inline-formula">_2.5</span> transport with the spatial–temporal variations over CEC. …”
Get full text

Assessing the resilience of child immunisation programmes using geospatial modelling and interrupted time series analysis in Ethiopia and Kenya amidst the COVID-19 pandemic: tracki... by McEwen Khundi, Themba Mzembe, Michael Give Chipeta, Chimwemwe Chifungo, Nyovani Janet Madise, Chifuniro Somanje Mankhwala, Tabitha Ngwira, Maame B Peterson

“…Interrupted time series analyses provided counterfactual coverage assessments, assuming no COVID-19 impact.Results At the national level, minor short-term disruptions in coverage were observed following pandemic peaks in Kenya and Ethiopia, which were considered statistically insignificant. In Ethiopia, a subnational assessment reveals that full vaccination coverage remained relatively stable, with significant changes observed in the southeast regions of Somali and Dire Dawa. …”
Get full text

Risk Factors of Bacteremia following Multiple Traumas by Hak-Jae Lee, Eol Choi, Nak-Joon Choi, Hyun-Woo Sun, Jae-Suk Lee, Jeong-Woo Lee, Tae-Yoon Kim, Yoon-Joong Jung, Suk-Kyung Hong

“…Gram-positive cocci were more frequently isolated in EOB than in LOB; otherwise, there was no statistical significance (77.8% vs. 64.7%, p=0.683). …”
Get full text

CEMP-1 Levels in Periodontal Wound Fluid during the Early Phase of Healing: Prospective Clinical Trial by Claudia Dellavia, Elena Canciani, Giulio Rasperini, Giorgio Pagni, Matteo Malvezzi, Gaia Pellegrini

“…There was a significant trend in CEMP-1 over time, and this trend was different among the 2 groups: the REG group showed a statistically significant rising CEMP-1 trend (0.18 ng/ml a week p=0.012), while the OFD had a trend that was significantly lower (-0.22 ng/ml a week compared to the REG group trend p=0.023), the OFD group lost on average 0.05 ng/ml a week. …”
Get full text

Chronic fatigue and headache in post-COVID-19 syndrome: a radiological and clinical evaluation by Gonçalo G. Almeida, Gonçalo G. Almeida, Saide Alkan, Saide Alkan, Robert Hoepner, André Euler, André Euler, Lara Diem, Franca Wagner

“…Brain MRI revealed T2-hyperintense lesions in 72% of patients, whereas spine MRI showed these lesions in only 16%. There was no statistically significant correlation between the presence of cerebral T2-hyperintense lesions and symptoms of fatigue (p = 0.815) or headaches (p = 0.178). …”
Get full text

Predictive factors of thrombosis during autologous stem cell transplantation in multiple myeloma: Experience from EHU Oran (Algeria) by Mohammed Amine BEKADJA, Brahim BENZINEB, Mansour BELKACEM, Hafida OUDJERIOUAT, Badra ENTASOLTAN, Soufi OSMANI, Kamila AMANI, Samira BOUCHAMA, Leila CHAREF, Mohamed BRAHIMI, Abdessamad ARABI, Rachir Amar BOUHASS, Nabil YAFOUR

“…Thepredictive factors studied are: age, co-morbidities, use of IMiDs, use of Granocyte colony stimualing factor in mobilization, the central venous catheter insertion site, cytapheresis count, CD34+ perfused, and finally deep venous thrombosis prophylaxis by a low molecular weight heparin .The statistical analysis focused on a univariate study, followed by a multivariate analysis using binary logistic regression. …”
Get full text