Analysis of Autoantibodies to 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase Using Different Technologies by Lucile Musset, Makoto Miyara, Olivier Benveniste, Jean-Luc Charuel, Alexander Shikhman, Olivier Boyer, Richard Fowler, Andrew Mammen, Joe Phillips, Michael Mahler

“…Anti-HMGCR antibodies are not always associated with the use of statin and appear to be the exclusive autoantibody specificity in patients with statin associated myopathies.…”
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The Association between KIF6 Single Nucleotide Polymorphism rs20455 and Serum Lipids in Filipino-American Women by Irma B. Ancheta, Cynthia A. Battie, Dan Richard, Christine V. Ancheta, Nancy Borja-Hart, Annabelle S. Volgman, Yvette Conley

“…However, those with the Arg/Arg genotype on statin medication exhibited a significantly higher mean triglycerides level (P<0.01). …”
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Non-HDL-c/TC: A Novel Lipid-Related Marker in the Assessment of Severity of Coronary Artery Lesions and Cardiovascular Outcomes by Anan Huang, Xin Qi, Liping Wei, Mingyin Zhang, Shiqi Zhou

“…Non-high-density lipoprotein cholesterol (non-HDL-c) predicts the severity of coronary artery lesions in patients not treated with statin. The association between non-HDL-c and severity of coronary artery lesions in patients treated with lipid-lowering therapy has been unknown. …”
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Assessing the impact of clinically relevant medicinal chemistry teaching: Learning gains from case study approach by Fernanda Domingues Lustoza, João Paulo S. Fernandes

“…A lecture containing pharmacological information on statins was delivered to the students from the control group. …”
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Rhabdomyolysis Induced by Coadministration of Fusidic Acid and Atorvastatin: A Case Report and Comprehensive Review of the Literature by Dimitrios Patoulias, Theodoros Michailidis, Thomas Papatolios, Rafael Papadopoulos, Petros Keryttopoulos

“…Statins are among the most widely prescribed medications worldwide. …”
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The Effects of Simvastatin on Proteinuria and Renal Function in Patients with Chronic Kidney Disease by Bancha Satirapoj, Anan Promrattanakun, Ouppatham Supasyndh, Panbuppa Choovichian

“…Current data suggests that statins might have beneficial effects on renal outcomes. …”
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Phase IV adaptive randomised clinical trials evaluating efficacy and cost-efficacy of pre-emptive pharmacogenetic genotyping strategies in the Spanish National Health System: iPHAR... by Xandra García-González, Alberto M Borobia, Antonio J Carcas, Miriam Estébanez, Montserrat Carmona, Irene García García, Francisco Abad-Santos, Luis A López-Fernández, Esther Cubo, Iñaki Imaz-Iglesia, Alicia Marín-Candón, Miriam Saiz-Rodríguez, Irene Taladriz-Sender, Pedro Arias, Rocío Rosas-Alonso, Enrique Seco-Meseguer, Stefan Stewart, Elena Diago-Sempere, María del Mar García Saiz, Emilio J Laserna-Mendieta, Ana M Peiró, Magí Farré, Consuelo Rodriguez-Jimenez, Judith Sanabria-Cabrera, Lucia Pedrosa, Ignacio Bernardino, Javier Guiijarro-Eguinoa, Arturo Gómez López De Las Huertas, Susana Martín-López, Olga Hladun Alvaro, Vicente Arrate, Ana Fries, Daniel Rodriguez Díaz, Fernando Marqués García, Núria Alonso Pedrol, Modesto M Maestre Muñiz, Leticia Rodríguez Alcolado, Carlos Ortiz-Bautista, Angela Remesal-Doblado, María Isabel Lucena, Zaida Salmón González, Inmaculada Coca-Prieto

“…After inclusion in the trial and genotyping has been performed, subjects will be randomly allocated to experimental group (pharmacogenetic genotype-guided statin prescription) or standard-of-care statin prescription (as deemed by attending physician). …”
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Low-Density Lipoprotein Cholesterol Levels in Coronary Artery Disease Patients: Opportunities for Improvement by Gary J. Martin, Meron Teklu, Edwin Mandieka, Joe Feinglass

“…At follow-up, 87.8% of patients were prescribed a statin, 9.7% were on ezetimibe, and 0.5% were on a PCSK9 inhibitor. …”
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Clinical Effect of Revascularization Strategies and Pharmacologic Treatment on Long-Term Results in Patients with Advanced Peripheral Artery Disease with TASC C and D Femoropoplite... by Chiu-Yang Lee

“…Kaplan–Meier curve analyses of time-to-primary cumulative AFS showed that nondiabetes mellitus, mild PAD, and cilostazol and statin treatment were correlated with a superior 3-year AFS (log rank test, P=0.001, P<0.001, P=0.009, and P=0.044, respectively). …”
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Gene Expression of Adhesion Molecules in Endothelial Cells from Patients with Peripheral Arterial Disease Is Reduced after Surgical Revascularization and Pharmacological Treatment by Franca Marino, Luigina Guasti, Matteo Tozzi, Laura Schembri, Luana Castiglioni, Elisabetta Molteni, Gabriele Piffaretti, Patrizio Castelli, Marco Cosentino

“…Patients were longitudinally evaluated 1 month before surgery, when statin treatment was established, at the time of surgery, and after 2 and 5 months. …”
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Comparative effects of pravastatin and rosuvastatin on carbohydrate metabolism in an experimental diabetic rat model by Kaya Hacer Kayhan, Demirtas Berjan, Yokus Beran, Kesim Dilek Aygün, Tasdemir Ezel, Sermet Abdurrahman

“…Statin treatment may increase the risk of diabetes; there is insufficient data on how statins affect glucose regulation and glycemic control and the effects of statins on liver enzymes related to carbohydrate metabolism have not been fully studied. …”
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Almanac 2015: coronary artery disease by D. Shavelle

“…These include assessment of novel biomarkers and imaging methods for patients at risk for coronary artery disease, care of patients with ST-segment elevation myocardial infarction, a novel device to treat medical refractory angina, use of non-statin lipid-lowering agents, a better understanding of the risks and benefits of longterm dual antiplatelet therapy and the use of the newer antiplatelet agents. …”
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Residual Dyslipidemia Leads to Unfavorable Outcomes in Patients with Acute Coronary Syndrome after Percutaneous Coronary Intervention by Bin Que, Chunmei Wang, Hui Ai, Xinyong Zhang, Mei Wang, Shaoping Nie

“…The present study aimed to evaluate the prevalence and prognosis of residual lipid abnormalities in statin-treated acute coronary syndrome (ACS) patients after percutaneous coronary intervention (PCI). …”
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Impact of duration of treatments with metformin and sulfonylureas, individually or in combination, on diabetic retinopathy among newly diagnosed type 2 diabetic patients: a pooled... by Mansour Bahardoust, Yadollah Mehrabi, Farzad Hadaegh, Davood Khalili, Ali Delpisheh

“…The cumulative exposure to metformin, SUs, aspirin, statin, and anti-hypertensive medication was also determined using the same approach. …”
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Myopathy with Concurrent Tadalafil and Simvastatin by Maria Pia Gargante, Marco Vacante, Cristina Russo, Mariano Malaguarnera

“…A 48-year-old man, using statin, was admitted to hospital with progressive myalgia after consumption of tadalafil and simvastatin. …”
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Role of high-density lipoprotein cholesterol in health and diseases by Brijesh Yadav, Narayan Prasad

“…In this review, we have discussed the different property of high-density lipoprotein cholesterol, its function and factors influencing HDLc property in light of anti-inflammatory activity in rheumatoid arthritis and the role of cholesterol-lowering statin drug in enhancing the beneficial effect of high-density lipoprotein cholesterol in different cell types.…”
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Adolescent with Rhabdomyolysis due to Undiagnosed Hypothyroidism by Raquel Farias Moeller, Nassim Zecavati, Rosa Sherafat-Kazemzadeh, Shoshana Aleinikoff, Wolfgang Rennert

“…Exercise-induced rhabdomyolysis has been described in military recruits, trained athletes and daily runners. Statin use, quail ingestion, infection by Epstein-Barr virus (EBV), and hypothyroidism, though rare, are risk factors for the development of rhabdomyolysis. …”
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Pure White Cell Aplasia and Necrotizing Myositis by Peter Geon Kim, Joome Suh, Max W. Adelman, Kwadwo Oduro, Erik Williams, Andrew M. Brunner, David J. Kuter

“…These findings were associated with a recent course of azithromycin and her daily use of a statin. Myositis improved on prednisone but PWCA persisted. …”
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Rosuvastatin, Sildenafil and Their Combination in Monocrotaline-Induced Pulmonary Hypertension in Rat by Jasińska-Stroschein Magdalena, Owczarek Jacek, Wesołowska Anna, Orszulak-Michalak Daria

“…There is considerable interest in the pleiotropic effects of statins and their potential role in the treatment of pulmonary hypertension. …”
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MANAGEMENT OF TYPE 2 DIABETES by Maitham Abdallah Albajy, Dan Florin Mihailescu

“…While SGLT2 inhibitors and GLP1 agents offer cardiovascular benefits, they should complement, not replace, statin therapy and blood pressure control for effective cardiovascular risk reduction.…”
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