Is ChatGPT an Accurate and Reliable Source of Information for Patients with Vaccine and Statin Hesitancy? by Cundullah TORUN, Abdurrahman SARMIS, Aytekin OGUZ

“…The mean scores of ChatGPT were 3.85+-0.34 for vaccination and 3.68+-0.35 for statin use. The mean scores of physicians were 3.73+-0.51 for vaccination and 3.58+-0.61 for statin use. …”
Get full text

Statin Induced Changes in Rat Pancreatic Tissue: A Histological and Biochemical Perspective by Abdullah Qamar, Hammad Gul Khan, Muhammad Marghoob Khan, Muhammad Rizwan Bashir Kiani, Hina Kundi, Fareeha Mushtaq

Get full text

The protective effect and experimental research progress of pleotropic statins in intervertebral disc degeneration by Xianxu Zhang, Shicheng Li, Xin Liu, Zhong Ma, Qiang Zhang, Yuji Zhang, Jiangdong An, Zhiqiang Luo

Subjects: Get full text

Association between statin administration and outcome in patients with sepsis: A retrospective study by Zhou Jianzhu, Feng Zeying, Qiu Hui, Li Tong, Huang Xin, Ye Ling, Huang Longjian, Guo Chengjun, Guo Chengxian, He Li

Subjects: Get full text

Statin-Associated Necrotizing Autoimmune Myositis Complicated by an Uncommon Adverse Effect to Treatment by Brian M. Fung, Emil R. Heinze, Andrew L. Wong

“…Unlike self-limited statin myopathy, this condition usually requires aggressive immunomodulation therapy to assist recovery and prevent future disability. …”
Get full text

β-Caryophyllene and Statins in Bone Fracture Healing – A Narrative Review by Marom H, Khan MA, Darvish N, Tornetta III P, Khoury A, Weil YA, Skelley NW, Allison DC, Meiron S, Ehrmann Barr T

“…Both BCP and statins have shown promising results in preclinical studies, enhancing bone density and promoting fracture healing. …”
Get full text

Statin prescriptions and progression of advanced fibrosis risk in primary care patients with MASLD by Andrew D Schreiner, William P Moran, Jingwen Zhang, Patrick D Mauldin, Justin Marsden, Mulugeta Gebregziabher, Chelsey A Petz, David G Koch, Chloe Bays

“…In the adjusted Cox model with statin prescription as the primary exposure, statins were associated with a lower risk (HR 0.60; 95% CI 0.45 to 0.80) of progressing to a FIB-4≥2.67. …”
Get full text

Subgingival Delivery of Statins as an Adjunct in the Non-Surgical Treatment of Periodontitis: A Systematic Review by Magdalena Maria Pietrzko, Maciej Pietrzko, Wojciech Niemczyk, Dariusz Skaba, Rafał Wiench

“…In recent years, studies have emerged suggesting additional clinical benefits from the use of statins as an adjunct to classical periodontal disease treatment. …”
Get full text

Spectrophotometric method for simultaneous determination of valsartan and substances from the group of statins in binary mixtures by Stolarczyk Mariusz, Apola Anna, Maślanka Anna, Kwiecień Anna, Opoka Włodzimierz

“…Applicability of derivative spectrophotometry for the determination of valsartan in the presence of a substance from the group of statins was checked. The obtained results indicate that the proposed method may be effective by using appropriate derivatives: for valsartan and fluvastatin - D1, D2 and D3, for valsartan and pravastatin - D1 and D3, for valsartan and atorvastatin - D2 and D3. …”
Get full text

Rhabdomyolysis Occurring under Statins after Intense Physical Activity in a Marathon Runner by Éric Toussirot, Fabrice Michel, Nicolas Meneveau

Get full text

Association of Statin, Metformin, and Aspirin Use With Hepatocellular Carcinoma in the All of Us Research Program by Erik Almazan, Raymond T. Chung

Get full text

Statin drugs enhance responses to immune checkpoint blockade in head and neck cancer models by Chrystal Paulos, Gregory B Lesinski, Zachary S Buchwald, Nabil F Saba, Vikash Kansal, Andre J Burnham, Brendan L C Kinney, Nicole C Schmitt

“…Background Anti-PD-1 immune checkpoint blockade is approved for first-line treatment of recurrent/metastatic head and neck squamous cell carcinoma (HNSCC), but few patients respond. Statin drugs (HMG-CoA reductase inhibitors) are associated with superior survival in several cancer types, including HNSCC. …”
Get full text

Response to Statin Therapy in Obstructive Sleep Apnea Syndrome: A Multicenter Randomized Controlled Trial by Marie Joyeux-Faure, Renaud Tamisier, Jean-Philippe Baguet, Sonia Dias-Domingos, Stephen Perrig, Georges Leftheriotis, Jean-Paul Janssens, Wojciech Trzepizur, Sandrine H. Launois, Françoise Stanke-Labesque, Patrick A. Lévy, Frédéric Gagnadoux, Jean-Louis Pepin

“…Accumulated evidence implicates sympathetic activation as inducing oxidative stress and systemic inflammation, which in turn lead to hypertension, endothelial dysfunction, and atherosclerosis in obstructive sleep apnea (OSA). Statins through their pleiotropic properties may modify inflammation, lipid profile, and cardiovascular outcomes in OSA. …”
Get full text

Statins Increase the Frequency of Circulating CD4+FOXP3+ Regulatory T Cells in Healthy Individuals by Ana Lucía Rodríguez-Perea, Carlos J. Montoya, Sven Olek, Claire A. Chougnet, Paula A. Velilla

“…Statins have been shown to modulate the number and the suppressive function of CD4+FOXP3+ T cells (Treg) in inflammatory conditions. …”
Get full text

Body mass index impacts the lipid-lowing effects of statins in patients with type 2 diabetes by Lulu Sun, Zhuo Wang, Bai Wang, Yuxiang Jia, Qidi Zhao, Jingjun Zhao, Xingtao Huang

Subjects: Get full text

Supplementation with Alpha-Tocopherol and Ascorbic Acid to Nonalcoholic Fatty Liver Disease’s Statin Therapy in Men by Nikola Hadzi-Petrushev, Katerina Dimovska, Nikola Jankulovski, Dine Mitrov, Mitko Mladenov

“…Oxidative stress and inflammation contribute to the pathogenesis and progression of nonalcoholic fatty liver disease (NAFLD), and the control of lipid status by statins may help to stop the progression of NAFLD. …”
Get full text

When herpes zoster is not herpes: A case of statin-induced myopathy complicated by drug allergies by Hira Khalid Kareem, Muhammad Fawad Ashraf, Muhammad Shehryar, Hafsa Fayyaz, Shreyas Patil

Subjects: “…Statin-induced myopathy…”
Get full text

The double-edged sword of statins in intracerebral hemorrhage patients: a systematic review and meta-analysis by Zheng Li, Wen-qi Xu, Jiao-qi Wang, Jia-hui Yang, Xiao-hua Shi, Cheng-bing Wang, Zhong-xin Xu, Jin-lan Jiang

Subjects: “…statin…”
Get full text

Response to Letter to the Editor, 'Is ChatGPT an Accurate and Reliable Source of Information for Patients with Vaccine and Statin Hesitancy?' by Cundullah TORUN, Abdurrahman SARMIS, Aytekin OGUZ

Get full text

High-intensity statin therapy in patients with chronic kidney disease: a systematic review and meta-analysis by Jing Wang, Ling Wu, Yu-Ling Yan, Bo Qiu, Song-Bai Deng, Xiao-Dong Jing, Jian-Lin Du, Ya-Jie Liu, Qiang She

“…Objective To evaluate the efficacy and safety of high-intensity statin therapy in patients with chronic kidney disease (CKD).Design A systematic review and meta-analysis.Data sources Randomised controlled trials (RCTs) comparing high-intensity statin therapy (atorvastatin 80 mg or rosuvastatin 20/40 mg) with moderate/mild statin treatment or placebo were derived from the databases (PubMed, Embase, Ovid, the Cochrane Central Register of Controlled Trials (CENTRAL) in the Cochrane Library, and ISI Web of Knowledge).Outcome measure Primary end points: clinical events (all-cause mortality, stroke, myocardial infarction and heart failure); secondary end points: serum lipid, renal function changes and adverse events.Results A total of six RCTs with 10 993 adult patients with CKD were included. …”
Get full text