Possible scenarios of sustainable supply chain in dairy industry with future research approach by Meysam Abedini, Narges Mohammadalipour, Ashraf Shahmansouri, Mahnaz Rabiei

“…According to the findings of the research, the factors influencing the driving forces and key uncertainties on the future of the sustainable supply chain in the dairy industry were identified, which include: foreign trade and communication regulations, the state of competition laws, attention to health and safety issues and standards, attention to Inventory maintenance for each product unit, foreign exchange rate fluctuations, inflation rate fluctuations, the cost of raw material production, the cost of spoilage of dairy products, and the motivation and willingness amount of private investors to invest in the dairy industry. …”
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Identification and leveling of factors affecting the acceptance of excellence model in Islamic Azad University by Seyedeh Somayeh Mousavi Siah Deleh, Samad Jabbari Asl, Musa Rezvani Chaman Zamin

“…Azad University has different branches, and consequently, it cannot be expected that its governing culture will be the same in terms of executive standards and implementation of the plan to accept the model of excellence. …”
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Presenting the model of work and technology curriculum in secondary schools of Fars province by Hamzeh Rahpeyma, Seyedahmad Hashemi, Abbas Gholtash

“…The research findings showed that according to the values ​​of standard coefficients and significant t coefficients, it can be said that the goals and content component (β = 0.63) has a significant role in the model, and the teaching and evaluation method component (β = 0.22) has a significant role in the program model of curriculum work and technology in secondary school. …”
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Investigating the mediating role of academic self-sufficiency and basic psychological needs in the relationship of social skills and social intelligence with academic achievement by Fatimeh Sabih Mahdi, Hasan ghalavandi

“…The statistical population consisted of 2110 students of the fifth grade of literature in Babol city, 327 of which were selected by random cluster sampling, using Morgan's table. Five standard questionnaires of social skills of Gresham and Elliott (1990), social intelligence of Silvera et al., (2001), psychological needs of Guardia et al., 2014) was used to collect the research data; the validity of the questionnaire was confirmed, and the reliability of the tool was confirmed using Cronbach's alpha coefficient in a preliminary study for social skills questionnaire 0.86, social intelligence 0.91, psychological needs 0.88, self-sufficiency 0.83, and academic progress 0.90. …”
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Wisdom of the Established Pattern by Joel Janhonen

“…Psychologically, maintaining the status quo requires less effort, intention, and awareness.[4] This clearly makes it our standard setting and a considerable cognitive bias. …”
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Multi-cancer early detection tests for general population screening: a systematic literature review by Ros Wade, Sarah Nevitt, Yiwen Liu, Melissa Harden, Claire Khouja, Gary Raine, Rachel Churchill, Sofia Dias

“…Data on the intervention(s), participant characteristics, setting, study design, reference standard test(s) used and relevant outcomes were extracted by one reviewer and independently checked by a second. …”
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Relationship between regional relative theta power and amyloid deposition in mild cognitive impairment: an exploratory study by Jaesub Park, Jaesub Park, Woo Jung Kim, Woo Jung Kim, Han Wool Jung, Han Wool Jung, Jae-Jin Kim, Jae-Jin Kim, Jin Young Park, Jin Young Park, Jin Young Park

“…Correlations between relative theta power and standardized uptake value ratios (SUVRs) in 12 brain regions were analyzed using Spearman’s correlation coefficient.ResultsSignificant positive correlations between relative theta power and SUVR values were found in several brain regions in the individualized brain model during the resting eyes-closed condition, including right temporal lobe (r = 0.581, p = 0.006), left hippocampus (r = 0.438, p = 0.047), left parietal lobe (r = 0.471, p = 0.031), right parietal lobe (r = 0.509, p = 0.018), left occipital lobe (r = 0.597, p = 0.004), and right occipital lobe (r = 0.590, p = 0.005). …”
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Dental and oral health assessments in the German National Cohort (NAKO) by Stefanie Samietz, Katrin Borof, Katrin Hertrampf, Ghazal Aarabi, Antonio Ciardo, Hannah Finke, Daniel Hagenfeld, Jan Kühnisch, Maurice Rütters, Sebastian-Edgar Baumeister, Stefan Lars Reckelkamm, Ti-Sun Kim, Thomas Kocher, Wolfgang Ahrens, Hermann Brenner, Carina Emmel, Beate Fischer, Amand Führer, Karin Halina Greiser, Jasmin Grischke, Kathrin Günther, Volker Harth, Stefanie Jaskulski, André Karch, Thomas Keil, Yvonne Kemmling, Alexander Kluttig, Lilian Krist, Oliver Kuss, Michael Leitzmann, Claudia Meinke-Franze, Karin B. Michels, Nadia Obi, Anette Peters, Nicole Pischon, Tobias Pischon, Sabine Schipf, Börge Schmidt, Henning Teismann, Stefan Rupf, Birte Holtfreter

“…Methods During baseline examinations (2014–2019), a total of 205,184 persons aged 19–74 years has been examined in 18 study centres, including, among others, a dental interview, stimulated saliva sampling, and recording of the numbers of present teeth and prostheses (standard Level 1 program). As part of the Level 2 program that was offered to 20% randomly selected participants, each study centre selected one of three modules, one of them being the Level 2 oral examination. …”
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A Randomized Study to Compare the Effects of Once-Weekly Dulaglutide Injection and Once-Daily Glimepiride on Glucose Fluctuation of Type 2 Diabetes Mellitus Patients: A 26-Week Fol... by Huiqin Li, Xiaohua Xu, Jie Wang, Xiaocen Kong, Maoyuan Chen, Ting Jing, Zhiying Zhang, Guoping Yin, Xiaomei Liu, Yun Hu, Lei Ye, Xiaofei Su, Jianhua Ma

“…The Mean Blood Glucose (MBG) of the two groups declined significantly after therapy (P<0.05). However, the Standard Deviation of Blood Glucose (SDBG) decreased significantly only in the dulaglutide group (from 2.57±0.74 mmol/L to 1.98±0.74 mmol/L, P<0.05). …”
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Factors influencing role preferences in decision-making of healthy women with BRCA1/2 pathogenic variants: subanalysis from a randomised controlled decision coaching trial by Sibylle Kautz-Freimuth, Arim Shukri, Claudia Stracke, Anna Isselhard, Birte Berger-Höger, Anke Steckelberg, Frank Vitinius, Nicola Dikow, Marion Kiechle, Cornelia Meisel, Achim Wöckel, Marion Tina von Mackelenbergh, Rita Schmutzler, Kerstin Rhiem, Stephanie Stock

“…The IG completed a decision-coaching (DC) programme, the CG received standard care. A second survey (T2) followed after 12 weeks. …”
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Computational analysis of heat transfer and fluid flow characteristics in a diamond microchannel heat sink with orthogonal ribs by Liang Du, Wenbo Hu, Ningkang Deng, Zhaoyang Zhang, Hongxing Wang

“…Effective thermal management technologies ensure that electronic equipment operates under optimal conditions, extends its service life, improves system integration and reliability, and ensures compliance with industry regulations and standards. Microchannel heat sinks are gaining increasing attention as an efficient thermal management solution. …”
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CD4 T cell dynamics shape the immune response to combination oncolytic herpes virus and BRAF inhibitor therapy for melanoma by Victoria Jennings, Kevin Harrington, Hardev Pandha, Alan Melcher, Adel Samson, Fiona Errington-Mais, Victoria Roulstone, Eva Crespo-Rodriguez, Galabina Bozhanova, Shane Foo, Emmanuel C Patin, Martin McLaughlin, Malin Pedersen, Richard Vile, Joan Kyula, Jehanne Hassan, Lizzie Appleton, Charleen ML Chan Wah Hak, Gabby Baker, Edward Armstrong, Matthew Chiu, Masahiro Ono

“…Background Combination herpes simplex virus (HSV) oncolytic virotherapy and BRAF inhibitors (BRAFi) represent promising immunogenic treatments for BRAF mutant melanoma, but an improved understanding of the immunobiology of combinations is needed to improve on the benefit of immune checkpoint inhibitors (ICI).Methods Using a BRAFV600E-driven murine melanoma model, we tested the immunogenicity of HSV/BRAFi in immunocompetent C57BL mice. In addition to standard FACS analysis, we used the ‘Timer of Cell Kinetics and Activity’ system, which can analyze the temporal dynamics of different T cell subsets. …”
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Exploring the ability of plasma pTau217, pTau181 and beta-amyloid in mirroring cerebrospinal fluid biomarker profile of Mild Cognitive Impairment by the fully automated Lumipulse®... by Marcella Catania, Claudia Battipaglia, Alberto Perego, Erika Salvi, Emanuela Maderna, Federico Angelo Cazzaniga, Paolo M. Rossini, Camillo Marra, Nicola Vanacore, Alberto Redolfi, Daniela Perani, Patrizia Spadin, Maria Cotelli, Stefano Cappa, Naike Caraglia, Pietro Tiraboschi, Fabrizio Tagliavini, Giuseppe Di Fede

“…However, their ability to reflect the cerebrospinal fluid (CSF) profile - that remains to date the gold standard for the biochemical diagnosis of AD - needs to be confirmed and validated before their implementation in clinical practice. …”
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Panitumumab plus 5-fluorouracil and folinic acid or 5-fluorouracil and folinic acid alone as maintenance therapy in RAS wild-type metastatic colorectal cancer (PanaMa, AIO KRK 0212... by Arndt Stahler, Meinolf Karthaus, Stefan Fruehauf, Ullrich Graeven, Lothar Müller, Ludwig Fischer von Weikersthal, Karel Caca, Eray Goekkurt, Alexej Ballhausen, Greta Sommerhäuser, Annabel H.S. Alig, Swantje Held, Armin Jarosch, David Horst, Anke Reinacher-Schick, Stefan Kasper, Volker Heinemann, Sebastian Stintzing, Tanja Trarbach, Dominik P. Modest

“…Interpretation: Panitumumab plus FU/FA might be considered a standard of care maintenance regimen since a potential re-induction therapy with panitumumab cannot be guaranteed at the time of maintenance treatment decision. …”
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Relation among zootechnical performance, biochemical indicators, water quality, and small invertebrates (zooplankton) abundance reared in biofloc-supplemented systems by Ahmed Said Al-Souti, Marwa M. Zaher, Amr M. Helal, Dina T. Meshhal, Mansour D. H., Afify D. G. Al-Afify, Mohamed M. Rafaey, Abeer El-Saharty, Ehab El-Haroun, Marian G. Nassif, Abdallah Tageldein Mansour, Abdallah Tageldein Mansour, Mohamed Ashour

“…The water quality indicated was within the standard values recommended for fish culture. Compared to those of the control group, the values of growth performance, whole-body biochemical composition, and blood biochemical indicators were significantly higher in biofloc groups than in the control group. …”
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Human versus Analogue Insulin for Youth with Type 1 Diabetes in Low-Resource Settings (HumAn-1): protocol for a randomised controlled trial by Éimhín Ansbro, Jing Luo, Chung-Chou H Chang, Kaushik Ramaiya, Bruce L Rollman, Sylvia Kehlenbrink, Sae-Rom Chae, Abigail Foulds, Claire Josey, Christina Lalama, Margaret L Prust, Bedowra Zabeen, Graham Ogle

“…Introduction Long-acting insulin analogues are the standard of care for people with type 1 diabetes (T1D) in high-income countries but remain largely inaccessible and understudied in low-resource settings. …”
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Phase I study of efineptakin alfa (NT-I7) for the treatment of Kaposi sarcoma by Leonard D’Amico, Martin Cheever, Steven P Fling, Anna Wright, Kathryn Lurain, Ramya Ramaswami, Irene Ekwede, Thomas S Uldrick, Robert Yarchoan, Judith C Kaiser, Angela Shaulov Kask, Manoj P Menon, Paul Couey, Eli Burnham, Allysson Angeldekao, Byung Ha Lee, Li-Lian Kwok, Chia-Ching Jackie Wang

“…Background CD4+ T-cell lymphocytopenia and immune dysfunction are factors that drive the onset and persistence of Kaposi sarcoma (KS) in people with (PWH) and without HIV. Standard chemotherapy agents for KS can contribute to increasing CD4+ T cell lymphocytopenia. …”
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Beta-hydroxy-beta-methylbutyrate (HMB) improves daily activity and whole-body protein metabolism in Duchenne muscular dystrophy dogs: a pilot study by Peter P. Nghiem, Alexis M. Rutledge, Kyle Tehas, Corine Kaderli, Meredith Poling, Sidney Arnim, Vitaliy Dernov, Celine van Sas, Macie L. Mackey, Gabriella A. M. ten Have, Mariëlle P. K. J. Engelen, Nicolaas E. P. Deutz

“…We tracked daily activity with an activity monitoring device and measured plasma creatine kinase and standard clinical biochemistry panels to monitor muscle and organ function. …”
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The prognostic association of triglyceride-glucose index and its derived indicators with stable coronary artery disease patients undergoing percutaneous coronary intervention by Yu Shan, Yu Shan, Maoning Lin, Maoning Lin, Fangfang Gu, Duanbin Li, Duanbin Li, Qiongjun Zhu, Qiongjun Zhu, Zhezhe Chen, Zhezhe Chen, Wenbin Zhang, Wenbin Zhang, Guosheng Fu, Guosheng Fu, Min Wang, Min Wang

“…Therefore, this study aims to investigate the association of the TyG index and its derived indicators, including the baseline TyG index, the baseline triglyceride glucose-body mass index (TyG-BMI), the mean TyG index, and the triglyceride glucose index-standard deviation (TyG-SD), with the prognosis of SCAD patients undergoing percutaneous coronary intervention (PCI).MethodsThis retrospective study enrolled 2,306 patients. …”
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Sex and outcomes of patients with microsatellite instability-high and BRAF V600E mutated metastatic colorectal cancer receiving immune checkpoint inhibitors by Michael Hoffmeister, Hermann Brenner, Chiara Cremolini, Sara Lonardi, Filippo Pietrantonio, Julien Taieb, David Tougeron, Robyn L Ward, Marco Vitellaro, Thierry André, Pierre Laurent-Puig, Jitendra Jonnagaddala, Francesca Bergamo, Raghav Sundar, Claire Gallois, Michael J Overman, Jakob Nikolas Kather, Lisa Salvatore, Romain Cohen, Rossana Intini, Priya Jayachandran, Miriam Koopman, Javier Ros, Marwan Fakih, Vincenzo Nasca, Giacomo Mazzoli, Jeanine M L Roodhart, Filippo Ghelardi, Elena Elez, Durgesh Wankhede, Marta Ligero, Joseph Zhao, Koen Zwart, Jeroen Derksen, Nicholas Hawkins, Javier Carmona

“…Background Immune checkpoint inhibitors (ICIs) are the gold standard therapy in patients with deficient mismatch repair (dMMR)/microsatellite instability-high (MSI-H) metastatic colorectal cancer (mCRC). …”
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