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14741
Negative valuation of ambiguous feedback may predict near-term risk for suicide attempt in Veterans at high risk for suicide
Published 2025-01-01“…Computational modeling was used to estimate latent cognitive variables including learning rates from positive and negative outcomes, and the subjective value of ambiguous feedback.ResultsOptimal responding on the reward-based trials was positively associated with upcoming ASA, and remained predictive even after controlling for other standard clinical variables such as current suicidal ideation severity and prior suicide attempts. …”
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14742
Functional near-infrared spectroscopy for the assessment and treatment of patients with disorders of consciousness
Published 2025-02-01“…Despite limitations such as low spatial resolution and the need for standardized protocols, fNIRS has demonstrated its utility in evaluating residual brain activity, detecting covert consciousness, and monitoring therapeutic interventions. …”
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14743
Postoperative radiotherapy improves survival in completely resected non-small cell lung cancer with pathologic N2 stage IIIA and positive lymph node count greater than one: a SEER-...
Published 2025-02-01“…While multimodal therapy is the standard for treating locally advanced NSCLC, the role of PORT remains controversial. …”
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14744
Proteasome inhibition enhances oncolytic reovirus therapy in multiple myeloma independently of its direct cytotoxic effects
Published 2025-01-01“…T-cell receptor (TCR) sequencing was also conducted both in immune competent MM mice and in patients enrolled in a phase 1b trial per a standard 3 + 3 dose escalation schedule. Results Here we show ex vivo and in vivo that proteasome inhibitors (PIs) potentiate reovirus replication in circulating classical monocytes, increasing viral delivery to myeloma cells. …”
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14745
Adenomas from individuals with pathogenic biallelic variants in the MUTYH and NTHL1 genes demonstrate base excision repair tumour mutational signature profiles similar to colorecta...
Published 2025-02-01“…Results: In biallelic MUTYH cases, SBS18+SBS36 signature proportions in adenomas (mean±standard deviation, 65.6 %±29.6 %) were not significantly different to those observed in CRCs (76.2 % ± 20.5 %, p-value=0.37), but were significantly higher compared with non-hereditary adenomas (7.6 % ± 7.0 %, p-value=3.4 × 10–4). …”
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14746
Surgical nonunion treatment of large-sized defects of femur and tibia based on the diamond concept
Published 2025-01-01“…Moreover, the proven “gold standard” of a two-step procedure, so called Masquelet technique, shows effectiveness. …”
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14747
The Topographic Relationships and Geographic Distribution of Prevascular Vitreous Fissures and Cisterns Assessed by Ultrawidefield En Face Vitreous Images
Published 2025-03-01“…Methods: For each eye, a 29 × 24-mm SS-OCT volume scan was obtained, along with standardized horizontal and vertical scans through the fovea. …”
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14748
Worldwide patterns and trends in ovarian cancer incidence by histological subtype: a population-based analysis from 1988 to 2017Research in context
Published 2025-01-01“…Annual percent changes were computed to describe trends in age-standardized rates (ASRs) of OC and its subtypes. Proportions of ASR for each subtype relative to the ASR of OC for individual countries were calculated. …”
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14749
Short-Term Effect of Air Pollution on Daily Hospital Visits for Anxiety Disorders in Southern China with Low Pollution Concentrations
Published 2025-01-01“…Although the daily levels of most pollutants (PM<sub>10</sub>, SO<sub>2</sub>, CO, NO<sub>2</sub> and O<sub>3</sub>) were consistently below China and WHO’s Ambient Air-Quality Standards, significant associations were observed between daily hospital visits for ADs and all six air pollutants. …”
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14750
Immunomodulatory and anti-inflammatory potential of botanicals bioactive product (PHYTO AX'CELL™) for an improvement of the well-being of laying hens at the peak of production
Published 2025-03-01“…This study was designed to assess the effectiveness of an authorized commercial standardized mixture of Artepillin-C, methyl-salicylates, flavonoids and curcuminoids (PHYTO AX'CELL™) provided intermittently during 8 weeks (wk) of trial to laying hens raised in enriched cages during the peak of the production, in the reduction of inflammation status, improving the immune response, and egg quality. …”
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14751
In Vitro Cultivation of Limbal Epithelial Stem Cells on Surface-Modified Crosslinked Collagen Scaffolds
Published 2019-01-01“…Human LESC were successfully cultivated on six out of seven hydrogel formulations, with primary cell cultures on CLP-12 EDC being deemed unsuccessful since the area of outgrowth did not meet quality standards (i.e., inconsistence in outgrowth and confluence) after 14 days of culture. …”
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14752
Establishing a baseline for surgical care in Mongolia: a situational analysis using the six indicators from the Lancet Commission on Global Surgery
Published 2022-07-01“…Protection against impoverishing and catastrophic expenditures was assessed against standard out-of-pocket expenditure at government hospitals for individual operations.Setting Mongolia’s 81 public hospitals with surgical capability, including tertiary, secondary and primary/secondary facilities.Participants All operative patients in Mongolia’s public hospitals, 2006–2016.Primary and secondary outcome measures Primary outcomes were national-level results of the indicators. …”
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14753
Identification of a novel heterozygous GPD1 missense variant in a Chinese adult patient with recurrent HTG-AP consuming a high-fat diet and heavy smoking
Published 2025-01-01“…It was found that there was a new variant of GPD1 gene-p.K327N, which was verified by gold standard-sanger sequencing method. In vitro, the corresponding plasmid was constructed and transfected into human renal HEK-293T cells, and GPD1 protein levels were detected. …”
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14754
Clinicopathologic characteristics, therapeutic modalities and survival outcomes of plasmablastic lymphoma: A real-world study
Published 2021-12-01“…Introduction Plasmablastic lymphoma (PBL), an extremely rare subtype of B-cell non-Hodgkin lymphoma (NHL), is characterized by aggressiveness, rapid progression and a bleak prognosis. Neither a standardized regimen nor a consensus for PBL treatment has been established. …”
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14755
Risks of parasitic helminth disease outbreaks and influence of physico-chemical factors in flood prone areas of Yaoundé, Cameroon
Published 2025-02-01“…Intestinal parasite resistant forms were identified using the basic sedimentation technique, while water parameters were assessed using standard procedures. Results: Results indicated that rivers in flood-prone areas are highly contaminated with a 75 % prevalence rate. …”
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14756
Determinants of infants and young children feeding practices among mothers living in Saudi Arabia: a cross-sectional study
Published 2025-01-01“…Conclusion Partial compliance with WHO CFP standards need improvement. Interventions should raise awareness of factors leading to poor compliance and support early breastfeeding initiation and continuation. …”
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14757
Optimization of the Antibacterial Activity of a Three-Component Essential Oil Mixture from Moroccan <i>Thymus satureioides</i>, <i>Lavandula angustifolia</i>, and <i>Origanum major...
Published 2025-01-01“…Additionally, <i>L. angustifolia</i> essential oil exhibited the strongest antioxidant activity, with IC<sub>50</sub> values of 84.36 µg/mL (DPPH), and 139.61 µg/mL (ABTS), surpassing both the other EOs and standard antioxidants like BHT and ascorbic acid in the ABTS assay. …”
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14758
Diagnostic accuracy of calculated serum osmolarity to predict dehydration in older people: adding value to pathology laboratory reports
Published 2015-10-01“…Objectives To assess which osmolarity equation best predicts directly measured serum/plasma osmolality and whether its use could add value to routine blood test results through screening for dehydration in older people.Design Diagnostic accuracy study.Participants Older people (≥65 years) in 5 cohorts: Dietary Strategies for Healthy Ageing in Europe (NU-AGE, living in the community), Dehydration Recognition In our Elders (DRIE, living in residential care), Fortes (admitted to acute medical care), Sjöstrand (emergency room) or Pfortmueller cohorts (hospitalised with liver cirrhosis).Reference standard for hydration status Directly measured serum/plasma osmolality: current dehydration (serum osmolality >300 mOsm/kg), impending/current dehydration (≥295 mOsm/kg).Index tests 39 osmolarity equations calculated using serum indices from the same blood draw as directly measured osmolality.Results Across 5 cohorts 595 older people were included, of whom 19% were dehydrated (directly measured osmolality >300 mOsm/kg). …”
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14759
Multicentre adaptive randomised trial of GvHD prophylaxis following unrelated donor stem cell transplantation comparing Thymoglobulin versus calcineurin inhibitor-based or sirolimu...
Published 2025-01-01“…The trial will compare the novel GvHD prophylaxis regimens post-transplant cyclophosphamide (PTCy) in combination with a CNI or sirolimus (PTCy-CNI or PTCy-sirolimus, respectively) to a current standard-of-care GvHD prophylaxis involving the use of Thymoglobulin (a specific brand of ATG containing rabbit polyclonal antibodies). …”
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14760
Modeling the relationship between the moral charter derived from Islamic teachings and performance with the mediating variable of employees' perception
Published 2024-11-01“…Examining the effect of the code of ethics on the performance of employees based on Islamic teachings helps to gain a better understanding of the impact of religious values on individual and organizational behavior and performance, and defines the performance of employees as a standard of progress, overtime, reward, punishment, revision and salary changes. …”
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