Investigation of vitamin D deficiency in girls with growth and development variations—a single center study by Panwang Huang, Panwang Huang, Beilei Zeng, Beilei Zeng, Feng Ren, Yuan Zhou, Yuan Zhou, Ye Li, Ye Li, Yinyin Huang, Yinyin Huang, Xingyu Liu, Xingyu Liu, Jiaxiu Zhou, Jiaxiu Zhou, Yaping Ma, Yaping Ma

“…The 25(OH)D <20 ng/ml was used as the standard for vitamin D deficiency.ResultsThe levels of vitamin D in the early puberty group, menarche group, obesity group, short stature group, and control group were as follows: 20.23 ± 5.90 ng/ml, 17.85 ± 5.69 ng/ml, 21.31 ± 8.99 ng/ml, 27.90 ± 12.27 ng/ml, and 29.42 ± 12.65 ng/ml, respectively. …”
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Investigating variability of craft microbreweries spent grains for classification and incorporation into precision diet formulation through multivariate analyses by Arturo Macias Franco, Aghata E.M. Silva, Tio Brody, Graham Holton, Macy Rockwell, Nelcino F. De Paula, Leilson R. Bezerra, Mozart A. Fonseca

“…Regarding gas and volatile fatty acids (VFA) production, clusters exhibited significant differences (P < 0.05) compared to an alfalfa standard, highlighting the diverse fermentation characteristics of BSG. …”
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Early Palliative Care Following Aborted Cancer Surgery: Results of a Prospective Feasibility Trial by Jordan M. Cloyd, MD, Rakhsha Khatri, BA, Angela Sarna, BS, Lena Stevens, PhD, Victor Heh, PhD, Mary Dillhoff, MD, Alex Kim, MD, Timothy M. Pawlik, MD, PhD, MPH, Aslam Ejaz, MD, Sharla Wells-Di Gregorio, PhD, Erin Scott, MD, Sachin S. Kale, MD

“…Secondary outcomes included changes in standardized measures of quality-of-life (QOL) and anxiety/depression during the 3-month follow-up. …”
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Assessing long term impact of regional climate and human activities on vegetation greenness dynamics in Sundarbans by Muhammad Sadiq Khan, Ayesha Akter, Ismail Khan, Luis Carlos Ramos Aguila, Lina Akter, Mengmeng Yang, Xu Li, Yuelin Li

“…We used long-term MODIS-NDVI data (2000−2020) alongside major climatic factors to analyze greenness trends, while also utilizing Landsat data (1989–2020) to assess human-induced disturbances in the Sundarbans landscape through standard land cover monitoring techniques. The results revealed a significant annual increase in greenness (0.0021/year, p = 0.01), with a more pronounced improvement in the wet season (0.0026/year, p = 0.001) compared to the dry season (0.0016/year, p = 0.05). …”
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Radiotherapy(R) Integration(I) Strategy for Small(S)-Cell Lung Cancer in Extensive(E) Stage (RISE) with up to 10 metastases- a study protocol of a randomized phase II trial by Łukasz Kuncman, Jacek Fijuth, Damian Tworek, Ewa Sierko, Paweł Cisek, Michał Masłowski, Maja Lisik-Habib, Magdalena Orzechowska, Katarzyna Galwas-Kliber, Adam Antczak, Izabela Chmielewska, Barbara Ziółkowska, Marta Kurczewska-Michalak, Wojciech Kuźnicki, Nina Jędrzejczak, Kinga Ranoszek, Mateusz Bilski

“…Abstract Background The current standard of care (SoC) for patients with extensive-disease small-cell lung cancer (ED-SCLC) is chemo-immunotherapy. …”
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Integrative computational analysis of anti-influenza potential in Caesalpinia mimosoides Lamk hydroethanolic extract by Anuwatchakij Klamrak, Shaikh Shahinur Rahman, Napapuch Nopkuesuk, Jaran Nabnueangsap, Jaraspim Narkpuk, Piyapon Janpan, Yutthakan Saengkun, Thananya Soonkum, Supawadee Sriburin, Samaporn Teeravechyan, Poramet Sitthiwong, Nisachon Jangpromma, Sirinan Kulchat, Kiattawee Choowongkomon, Rina Patramanon, Arunrat Chaveerach, Jureerut Daduang, Sakda Daduang

“…The C. mimosoides hydroethanolic extract exhibited potent antioxidant activity in the DPPH assay, with an IC50 value of 15.01 µg/mL, comparable to authentic quercetin (IC50 = 12.72 µg/mL) and approximately 4.91 times greater than standard gallic acid (IC50 = 3.06 µg/mL). Through untargeted metabolomic analyses (UPLC-ESI(±)-QTOF-MS/MS) and subsequent stepwise computational metabolomics analyses, we identified the extract as primarily containing simple phenolics (e.g., gallic acid, ellagic acid, shikimic acid, and chlorogenic acid), flavonoid derivatives (e.g., quercetin, taxifolin, myricitrin, and afzelin), and other bioactive components, including dicarboxylic acids and germacrone. …”
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Optimizing hip MRI: enhancing image quality and elevating inter-observer consistency using deep learning-powered reconstruction by Yimeng Kang, Wenjing Li, Qingqing Lv, Qiuying Tao, Jieping Sun, Jinghan Dang, Xiaoyu Niu, Zijun Liu, Shujian Li, Zanxia Zhang, Kaiyu Wang, Baohong Wen, Jingliang Cheng, Yong Zhang, Weijian Wang

“…Conclusion Integrating deep learning-based reconstruction methods into standard clinical workflows has the potential to the promise of accelerating image acquisition, enhancing image clarity, and increasing patient throughput, thereby optimizing diagnostic efficiency. …”
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Breaking the biofilm barrier: Juglone derivatives as dual-action inhibitors and anti-quorum sensing agents by Muhammad Abdullah Bhatti, Atif Ali Khan Khalil, Sayed Muhammad Ata Ullah Shah Bukhari, Faisal Hanif, Mi-Jeong Ahn, Sumra Wajid Abbasi, Nazir Ahmed Lone, Wen-Jun Li, Wasim Sajjad

“…The suppression of S. aureus β-hemolytic, coagulase and proteolytic activity was evaluated using standard assay protocols. High Performance Liquid Chromatography (HPLC) was performed to analyze the acyl homoserine lactones (AHLs) signals degradation by juglone derivatives. …”
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Changes in clinical and imaging variables during withdrawal of heart failure therapy in recovered dilated cardiomyopathy by Brian P. Halliday, Ruth Owen, John Gregson, Ali Vazir, Rebecca Wassall, Zohya Khalique, Amrit S. Lota, Upasana Tayal, Daniel J. Hammersley, Richard E. Jones, Dudley J. Pennell, Martin R. Cowie, John G.F. Cleland, Sanjay K. Prasad

“…Amongst the 49 patients [35% women, mean age 53.6 years (standard deviation 11.6)] who withdrew therapy, 20 relapsed. …”
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The origin and transmission of HIV-1 CRF80_0107 among two major first-tier cities in China by Xiaorui Wang, Bo Zhu, Hanping Li, Jingwan Han, Xiaolin Wang, Lei Jia, Bohan Zhang, Jingyun Li, Linding Wang, Yongjian Liu, Hongling Wen, Lin Li

“…Methods With the partial pol region fragment of the HIV-1 CRF80_0107 subtype standard sequence as a reference, BLAST was used to search for highly similar sequences in the Los Alamos HIV Sequence Database, followed by preliminary subtype identification via COMET. …”
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RETRACTED ARTICLE: Synthesis of silver nanoparticles using Plantago lanceolata extract and assessing their antibacterial and antioxidant activities by Muhammad Zahir Shah, Zheng-Hui Guan, Ala Ud Din, Amjad Ali, Ata Ur Rehman, Kashif Jan, Shah Faisal, Shah Saud, Muhammad Adnan, Fazli Wahid, Saud Alamri, Manzer H. Siddiqui, Shamsher Ali, Wajid Nasim, Hafiz Mohkum Hammad, Shah Fahad

“…NPs achieved a peak antioxidant capacity of 62.43 ± 2.4 and 16.85 ± 0.4 μg mL−1, compared to standard (69.60 ± 1.1 at 100 μg mL−1) with IC50 (369.5 ± 13.42 and 159.5 ± 10.52 respectively). …”
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Translingual neural stimulation induced changes in intra- and inter-network functional connectivity in mild-moderate traumatic brain injury patients by Daniel Y. Chu, Jiancheng Hou, Thomas Hosseini, Veena A. Nair, Nagesh Adluru, Yuri Danilov, Kurt A. Kaczmarek, Mary E. Meyerand, Mitchell Tyler, Mitchell Tyler, Vivek Prabhakaran

“…IntroductionMild-to-moderate traumatic brain injury (mmTBI) that lead to deficits in balance and gait are difficult to resolve through standard therapy protocols, and these deficits can severely impact a patient's quality of life. …”
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Pharmacological interventions for the management of anesthesia and sedation in patients with Duchenne muscular dystrophy: a systematic review and meta-analysis by Xianghong Lian, Xianghong Lian, Xianghong Lian, Yang Jing, Yang Jing, Yang Jing, Ting Luo, Ting Luo, Ting Luo, Yixin Guo, Yixin Guo, Yixin Guo, Yunzhu Lin, Yunzhu Lin, Yunzhu Lin

“…Data from the eligible studies were combined to calculate pooled risk ratios or standardized mean differences, and some included studies are presented in a narrative synthesis.ResultsForty studies with 196 DMD participants were included in the analysis. …”
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Microplastic analysis in soils: A comparative assessment by Stoyana Peneva, Quynh Nhu Phan Le, Davi R. Munhoz, Olivia Wrigley, Flora Wille, Heidi Doose, Crispin Halsall, Paula Harkes, Michael Sander, Melanie Braun, Wulf Amelung

“…Yet, our data indicate that adding stained large MiP as an internal standard could enhance extraction control, while Soxhlet-extraction with subsequent 1H NMR analysis is most powerful for controlling future thresholds of small MiP from biodegradable materials.…”
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Pancreatoduodenectomy without Vascular Resection in Patients with Primary Resectable Adenocarcinoma and Unilateral Venous Contact: A Matched Case Study by Luca Morelli, Raffaella Berchiolli, Simone Guadagni, Matteo Palmeri, Niccolò Furbetta, Desirée Gianardi, Matteo Bianchini, Niccola Funel, Giovanni Caprili, Luca Emanuele Pollina, Giulio Di Candio, Franco Mosca, Gregorio Di Franco, Alfred Cuschieri

“…We identified a group of 40 (25.6%) patients with prVC-PDAC in whom after checking the feasibility with intraoperative ultrasound, we were able to perform PD by separation of the tumor from the portomesenteric axis avoiding vascular resection, without residual macroscopic disease (no vascular resection, nvrPD), and compared this group, using case-matched methodology, with the standard PD (sPD) group of primary resectable without vascular contact- (prwVC-) PDAC. …”
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Comparison of Therapeutic Effects of Different Rehabilitation Methods on Patients Undergoing Total Knee Arthroplasty: A Network Meta‐Analysis of Randomized Controlled Trials by Zhaokai Jin, Yi Tang, Hua Huang, Lei Chen, Zhongyi Zhang, Tianyou Ma, Zhengming Wang, Hai Su, Haojing Zhou, Shuaijie Lv, Peijian Tong

“…A Bayesian network meta‐analysis (NMA) was carried out for calculating standardized mean difference (SMD) and the surface under cumulative ranking curve (SUCRA) of improvement of knee joint function after TKA by different rehabilitation methods. …”
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The effects of ultra-selective beta1-antagonism on the metabolic and cytokine profile in septic shock patients receiving noradrenaline: a sub-investigation from the STRESS-L Random... by Jarrod L. Thomas, Kirsty C. McGee, Anower Hossain, Gavin D. Perkins, Anthony C. Gordon, Duncan Young, Danny McAuley, Mervyn Singer, Ranjit Lall, Tina Kramaric, Janet M. Lord, Tony Whitehouse, Luis A. J. Mur, for the STRESS-L. collaborators

“…Following adjusted analysis for confounders, plasma metabolite concentrations remained statistically different between landiolol and standard care arms for succinic acid, l-tryptophan, l-alanine, 2,2,2-trichloroethanol, lactic acid and d-glucose. …”
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Informatization of the processes of administration of the quality of medical services in surgical hospitals by Ya.S. Bereznytskyi, V.Ya. Bereznytskyi, O.V. Hudoshyna, N.D. Chuhrienko, G.V. Bereznytska, Ye.V. Zalyhina, Yu.B. Dianova, E.A. Rynska, L.N. Ksykevich

“…Control of patient safety and the quality of the provided medical services requires constant verification of their implementation and paying attention to be up to standards, the occurrence of deviations and complications. …”
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Surgery for Patients With cT3/4N2M0, Stage IIIB NSCLC. Is It Time to Redefine Resectability? by J. Humberto Rodriguez-Quintero, MD, MPH, Rajika Jindani, MD, MPH, MS, Roger Zhu, MD, Isaac Loh, Mohamed K. Kamel, MD, Anne Montal, MD, Marc Vimolratana, MD, MS, Neel P. Chudgar, MD, Nitin Ohri, MD, MS, Balazs Halmos, MD, MS, Brendon M. Stiles, MD

“…Introduction: Chemoradiation followed by durvalumab is considered a standard approach for patients with locally advanced NSCLC. …”
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Investigating the neuroprotective effects of Dracocephalum moldavica extract and its effect on metabolomic profile of rat model of sporadic Alzheimer's disease by Marjan Talebi, Seyed Abdulmajid Ayatollahi, Mohammad Ali As’Habi, Farzad Kobarfard, Mona Khoramjouy, Farzaneh Niki Boroujeni, Mehrdad Faizi, Alireza Ghassempour

“…The DM extract was standardized and quantified based on examining total phenolic, total flavonoid, rosmarinic acid, and quercetin contents using colorimetry and high-performance liquid chromatography (HPLC) methods. …”
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