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  1. 14581

    Acupuncture for somatosensory deficits after stroke: a systematic review and meta-analysis by Shumeng Ren, Yuhang Chen, Yu Liu, Qiuyi Lv, Jing Peng, Lei Song, Yihuai Zou, Hua Zhang, Xing Chen

    Published 2025-02-01
    “…The acupuncture also showed an improvement in the ability of daily living [MD = 12.19, 95% CI (8.50, 15.87), I2 = 97.2%, P < 0.001] and the symptoms of neurological deficit [Standardized Mean Difference (SMD) = −1.53, 95%CI (−2.04, −1.03), I2 = 89.7%, P < 0.001].ConclusionsThe current best evidence shows that acupuncture has advantages in raising the effective rate, alleviating sensory disturbance, relieving pain, enhancing the ability of daily living, and improving the symptoms of neurological deficits for somatosensory deficits after stroke compared with the control group. …”
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  2. 14582

    Solving unknown primary cancer with earlier diagnosis - the SUPER-ED trial: study protocol for a stepped-wedge cluster randomised controlled trial to support earlier diagnosis for... by Anna Ugalde, Richard W. Tothill, Stephen Quinn, Hui-Li Wong, Owen Prall, Catherine Mitchell, Nilmini Wickramasinghe, Clare Fedele, Natalie Richards, Elizabeth Todio, Cindy Bryant, Louisa G. Collins, Sarah McLean, Hyun Soo Ko, Tim Akhurst, Christopher Steer, Bo Gao, Mark Wong, Chloe Georgiou, Narayan Karanth, Anna Kuchel, Louise Nott, Shamsudheen Padinharakam, Mark Shackleton, Ian M. Collins, Madhu Singh, Rachel Wong, Zee Wan Wong, Alexis Butler, Tharani Sivakumaran, Penelope Schofield, Linda Mileshkin

    Published 2025-01-01
    “…Methods/design This is a pragmatic stepped-wedge cluster randomised trial comparing a control phase of standard practice with an intervention phase. Patient inclusion criteria are: 1) age 18 years or older, 2) presenting with suspected metastatic malignancy without an obvious primary site on imaging, 3) clinically appropriate to undergo diagnostic work-up and 4) able to provide written or verbal consent. …”
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  3. 14583

    Efficacy of first-line chemotherapy combined with immunotherapy or anti-angiogenic therapy in advanced KRAS-mutant non-small cell lung cancer by Huiping Qiang, Yue Wang, Yao Zhang, Jingwen Li, Lincheng Zhang, Huawei Du, Xuxinyi Ling, Shuhui Cao, Yan Zhou, Runbo Zhong, Hua Zhong

    Published 2025-03-01
    “…First-line chemotherapy combined with immunotherapy has been the standard therapeutic regimen for KRAS-mutant NSCLC patients. …”
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  4. 14584

    Long-term trends in the prevalence of cardiovascular-kidney-metabolic syndrome in South Korea, 2011–2021: a representative longitudinal serial studyResearch in context by Yesol Yim, Jae E. Lee, Yejun Son, Soeun Kim, Hojae Lee, Sooji Lee, Wonwoo Jang, Hanseul Cho, Hayeon Lee, Kyeongmin Lee, Hyesu Jo, Jaeyu Park, Jiyeon Oh, Louis Jacob, Jiseung Kang, Hyunji Sang, Sang Youl Rhee, Dong Keon Yon

    Published 2025-02-01
    “…CKM syndrome was defined using the PREVENT equations, categorizing individuals into five stages (0–4). Age-standardized prevalence rates, annual percent changes (APC), and sociodemographic disparities were analyzed using multinomial logistic regression and Joinpoint regression. …”
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  5. 14585

    Association between migraine severity and sleep quality: a nationwide cross-sectional study by Nura A. Almansour, Nura A. Almansour, Seham S. Alsalamah, Seham S. Alsalamah, Razan S. Alsubaie, Razan S. Alsubaie, Nada N. Alshathri, Nada N. Alshathri, Yasmeen A. Alhedyan, Yasmeen A. Alhedyan, Faisal Y. Althekair’s, Faisal Y. Althekair’s, Faisal Y. Althekair’s

    Published 2025-01-01
    “…This study therefore aimed to determine the association between sleep quality and migraine severity.MethodsA comparative cross-sectional study was conducted with 1,399 participants across all regions of Saudi Arabia from August to October 2023 using standardized questionnaires. Participants were categorized into patients with migraine and non-migraine patients, according to the International Headache Society (IHS) criteria. …”
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  6. 14586

    Surgical resection, radiotherapy and percutaneous thermal ablation for treatment of stage 1 non-small cell lung cancer: protocol for a systematic review and network meta-analysis by Arun Chockalingam, Menelaos Konstantinidis, Brandon Koo, John Timothy Moon, Andrew Tran, Sahar Nourouzpour, Emily Lawson, Kathleen Fox, Peiman Habibollahi, Bruno Odisio, Mohammed Loya, Ali Bassir, Nariman Nezami

    Published 2022-06-01
    “…Currently, surgical resection is the gold standard of treatment. However, as patients are becoming medically more complex presenting with advanced disease, minimally invasive image-guided percutaneous ablations are gaining popularity. …”
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  7. 14587

    Diagnostic Accuracy of Detective Flow Imaging Endoscopic Ultrasonography for Evaluating Blood Flow Within Mural Nodules of Intraductal Papillary Mucinous Neoplasms by Kazuki Endo, Haruo Miwa, Kazuya Sugimori, Kozue Shibasaki, Shoichiro Yonei, Yugo Ishino, Shotaro Tsunoda, Hayato Yoshimura, Akihiro Funaoka, Hiromi Tsuchiya, Ritsuko Oishi, Yuichi Suzuki, Satoshi Komiyama, Takashi Kaneko, Manabu Morimoto, Kazushi Numata, Shin Maeda

    Published 2025-01-01
    “…The diagnostic capability of DFI-EUS to detect MN blood flow was assessed with CE-EUS as the gold standard. Secondary outcomes included inter-reader agreement, the correlation between MN size and detection rates, and the association between DFI blood flow signal patterns and malignancy of MNs in surgically resected cases. …”
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  8. 14588

    Site-specific immunoglobulin G N-glycosylation is associated with gastric cancer progression by Tingting Xu, Jianmin Huang, Jiajing Lin, Yuanyuan Liu, Yi Wang, Wenkang Shen, Jianjie He, Shuyun Chen, Xi Zhu, Yuqin Que, Mengting Hu, Yu Chen, Liming Cheng, Honghao He, Xin Liu, Si Liu

    Published 2025-02-01
    “…Additionally, interleukin-11 (IL-11) levels were quantified using a standardized enzyme-linked immunosorbent assay (ELISA). …”
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  9. 14589

    Revealing the heterogeneity of treatment resistance in less‐defined subtype diffuse large B cell lymphoma patients by integrating programmed cell death patterns and liquid biopsy by Wei Hua, Jie Liu, Yue Li, Hua Yin, Hao‐Rui Shen, Jia‐Zhu Wu, Yi‐Lin Kong, Bi‐Hui Pan, Jun‐Heng Liang, Li Wang, Jian‐Yong Li, Rui Gao, Jin‐Hua Liang, Wei Xu

    Published 2025-01-01
    “…To identify robust prognostic biomarkers that can guide personalized management for less‐defined subtype DLBCL patients, we integrated multi‐omics data derived from 339 standard R‐CHOP‐treated patients diagnosed with less‐defined subtype DLBCL from three independent cohorts. …”
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  10. 14590

    Designing a model for fostering organizational resilience based on organizational agility components by Heidar kadivar zinkanloo, gholamabbas shekari, saeed emamgholizadeh

    Published 2024-11-01
    “…As many as 249 questionnaires were distributed among students and consequently 230 questionnaires were returned. Four standard questionnaires of cognitive coordination (Harmon Jones et al., 2007), systemic thinking (Dolansky et al., 2020), scientific reasoning (Golombic et al., 2022), and critical thinking (Watson and Glaser, 2002) were used to collect research data; and, students' GPA was used in order to measure academic progress. …”
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  11. 14591

    The relationship between cognitive dissonance, scientific reasoning and systemic thinking with the academic progress of Babol University physics students with the mediating role of... by Akram Kamel Zaherolmahni, Mohammad hassani, Hasan ghalavandi

    Published 2024-11-01
    “…As many as 249 questionnaires were distributed among students and consequently 230 questionnaires were returned. Four standard questionnaires of cognitive coordination (Harmon Jones et al., 2007), systemic thinking (Dolansky et al., 2020), scientific reasoning (Golombic et al., 2022), and critical thinking (Watson and Glaser, 2002) were used to collect research data; and, students' GPA was used in order to measure academic progress. …”
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  12. 14592

    Deciphering the effect of exercise timing on glucose metabolism: a randomised controlled trial by Fabienne Bruggisser, Denis Infanger, Henner Hanssen, Raphael Knaier

    Published 2025-01-01
    “…The effect sizes were calculated using the baseline standard deviation of the parameter to provide a standardised measure. …”
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  13. 14593

    Investigating causal relationships between entrepreneurial education and sustainable employment generation in Islamic Azad Universities in Tehran by Sana Abdulali, Mohammad Naghi Imani GelepordesariI, Asghar Sharifi

    Published 2024-08-01
    “…The findings of the research showed that according to the values ​​of the standard coefficients and the significant coefficients of T (above 2.58), it can be said that there are direct relationships between the factors. …”
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  14. 14594

    600 meters to VO2max: Predicting Cardiorespiratory Fitness with an Uphill Run by Kübra Stoican, Regina Oeschger

    Published 2025-01-01
    “…Regarding the performance of VO2max estimation, the MLR model achieved an R2 of 0.77 with a standard error of the estimate (SEE) of 3.4 mL·kg-1·min-1, the XGBoost model an R2 of 0.82 with a SEE of 3.0 mL·kg-1·min-1, and the MLP model an R2 of 0.94 with a SEE of 1.6 mL·kg-1·min-1. …”
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  15. 14595
  16. 14596

    TEC-ADHERE: Real-World Persistence and Adherence on Dimethyl Fumarate in Patients with Relapsing–Remitting Multiple Sclerosis in the French OroSEP Patient-Support Program by Pierre Labauge, Alain Créange, Thibault Moreau, Jocelyne Nouvet-Gire, Bernard Pedespan, Olivier Heinzlef, Nathalie Texier, Marilyn Gros, Catherine Marti, Marta Ruiz, Mikel Martinez, Giovanni Castelnovo

    Published 2024-11-01
    “…Outcomes were compared for patients in OroSEP versus non-OroSEP patients who received their neurologists’ standard of care (SoC). Patients initiated DMF at month 0 (M0); follow-up visits occurred at M3 and M6. …”
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  17. 14597

    Predicting Axillary Lymph Node Metastasis in Young Onset Breast Cancer: A Clinical-Radiomics Nomogram Based on DCE-MRI by Dong X, Meng J, Xing J, Jia S, Li X, Wu S

    Published 2025-01-01
    “…Precisely forecasting axillary lymph node metastasis (ALNM) is essential for customizing treatment plans and enhancing patient results.Objective: This research sought to create and verify a clinical-radiomics nomogram that combines radiomic features from Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) with standard clinical predictors to improve the accuracy of predicting ALNM in young breast cancer patients.Methods: We performed a retrospective analysis at one facility, involving the creation and validation of a nomogram in two stages.At first, a medical model was developed utilizing conventional indicators like tumor dimensions, molecular classifications, multifocal presence, and MRI-determined ALN status.A more detailed clinical-radiomics model was subsequently developed by integrating radiomic characteristics derived from DCE-MRI images.These models were created using logistic regression analyses on a training dataset, and their effectiveness was assessed by measuring the area under the receiver operating characteristic curve (AUC) in a separate validation dataset.Results: The clinical-radiomics nomogram surpassed the clinical-only model, recording an AUC of 0.892 in the training dataset and 0.877 in the validation dataset.Significant predictors included MRI-reported ALN status and select radiomic features, which markedly enhanced the model’s predictive capacity.Conclusion: Integrating radiomic features with clinical predictors in a nomogram significantly improves ALNM prediction in young onset breast cancer, providing a valuable tool for personalized treatment planning. …”
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  18. 14598

    Developing a Prototype Machine Learning Model to Predict Quality of Life Measures in People Living With HIV by Mercadal-Orfila G, Serrano López de las Hazas J, Riera-Jaume M, Herrera-Perez S

    Published 2025-01-01
    “…Additionally, the model demonstrated strong reliability in maintaining standardized prediction errors below 0.2 for most instruments, with probabilities of achieving this threshold being 96.43% for WHOQoL HIV Bref and 88.44% for ESTAR, while lower probabilities were observed for TSQM (44%) and WRFQ (51%).Conclusion: The results from our machine learning algorithms are promising for predicting PROMs and PREMs in AIDS settings. …”
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  19. 14599

    Faktor-Faktor yang Berhubungan dengan Perilaku Bidan dalam Pencegahan Risiko Penularan HIV/AIDS pada Pertolongan Persalinan Normal di Kota Tanjungpinang Tahun 2014 by Rahmadona ., Joserizal Serudji, Erwani .

    Published 2014-09-01
    “…Prevention risk of HIV/AIDS transmission in normal delivery assistance reflected from their behaviour by implementing standard precaution. This study aimed to analyze factors related to midwives behaviour toward prevention risk of HIV/AIDS transmission in normal delivery assistance in Tanjungpinang city year 2014.This is analytical observasional study with cross sectional approach to 39 midwives using self administered questionare and observasional guided forms. …”
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  20. 14600

    Physical behaviours during pregnancy may alter the association of maternal insulin sensitivity with neonatal adiposity: a prospective pre-birth cohort of mother-child pairs by Piraveena Satkunanathan, Catherine Allard, Myriam Doyon, Patrice Perron, Luigi Bouchard, Marie-France Hivert, Tricia M. Peters

    Published 2025-01-01
    “…Among a subset of neonates (n = 265), trained research staff measured skinfold thickness using a calibrated skinfold caliper following standardized protocols to estimate neonatal adiposity. …”
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