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  1. 10621

    Are we serologically prepared against an avian influenza pandemic and could seasonal flu vaccines help us? by Iván Sanz-Muñoz, Javier Sánchez-Martínez, Carla Rodríguez-Crespo, Corina S. Concha-Santos, Marta Hernández, Silvia Rojo-Rello, Marta Domínguez-Gil, Ahmed Mostafa, Luis Martinez-Sobrido, Jose M. Eiros, Aitor Nogales

    Published 2025-02-01
    “…These findings demonstrate the importance of vaccination and suggest that seasonal influenza vaccines could be used as a first line of defense against an eventual pandemic caused by avian influenza viruses, to be followed immediately by the use of more specific pandemic vaccines.IMPORTANCEInfluenza A viruses (IAV) can infect and replicate in multiple mammalian and avian species. Avian influenza virus (AIV) is a highly contagious viral disease that occurs primarily in poultry and wild water birds. …”
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  2. 10622

    Synthesizing field plot and airborne remote sensing data to enhance national forest inventory mapping in the boreal forest of Interior Alaska by Pratima Khatri-Chhetri, Hans-Erik Andersen, Bruce Cook, Sean M. Hendryx, Liz van Wagtendonk, Van R. Kane

    Published 2025-06-01
    “…Climate change has increased the temperature, frequency, severity, and amount of area burned, which is leading to changes in the spatial extent of forest type and species range. These rapid ecological shifts necessitate fine-scale monitoring of forest type to detect potential type conversions and guide management interventions. …”
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  3. 10623

    Injectable Nanocomposite Hydrogel for Accelerating Diabetic Wound Healing Through Inflammatory Microenvironment Regulation by Chen Y, Li Y, Song H, Liu X, Zhang H, Jiang J, Liu H, Zhuo R, Cheng G, Fang J, Xu L, Qi Y, Sun D

    Published 2025-02-01
    “…The incorporation of ZIF-8@Cur confers the hydrogel with exceptional antibacterial properties and the capability to eliminate reactive oxygen species (ROS). Moreover, the pH-responsive MCC@ZIF-8@Cur hydrogel continuously releases Cur and Zn2+, mitigating inflammation, inducing M2 polarization of macrophages, and promoting angiogenesis. …”
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  4. 10624

    Antioxidant Properties of Tonsil-Derived Mesenchymal Stem Cells on Human Vocal Fold Fibroblast Exposed to Oxidative Stress by Sung-Chan Shin, Hyung-Sik Kim, Yoojin Seo, Cho Hee Kim, Ji Min Kim, Hyun-Keun Kwon, Jin-Choon Lee, Eui-Suk Sung, Byung-Joo Lee

    Published 2020-01-01
    “…Cell viability and reactive oxygen species (ROS) production were assessed to examine the progression of oxidative stress in vitro. …”
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  5. 10625

    Germline Single-Nucleotide Polymorphism <i>GFI1-36N</i> Causes Alterations in Mitochondrial Metabolism and Leads to Increased ROS-Mediated DNA Damage in a Murine Model of Human Acu... by Jan Vorwerk, Longlong Liu, Theresa Helene Stadler, Daria Frank, Helal Mohammed Mohammed Ahmed, Pradeep Kumar Patnana, Maxim Kebenko, Eva Dazert, Bertram Opalka, Nikolas von Bubnoff, Cyrus Khandanpour

    Published 2025-01-01
    “…Since we have demonstrated that GFI1 plays an active role in metabolism, in this study, we investigated whether increased levels of reactive oxygen species (ROS) could contribute to the accumulation of genetic damage in <i>GFI1-36N</i> leukemic cells. …”
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  6. 10626

    Research on ion cyclotron emission driven by deuterium–deuterium fusion-produced tritium ions on the Experimental Advanced Superconducting Tokamak by Huapeng Zhang, Lunan Liu, Wei Zhang, Xuan Sun, Xinjun Zhang, Zhengshuyan Wang, Zelin Xu, Jiadong Zhang, Weijian Qin, Liuxin Li, Yuhao Jiang, Sichun Qiu, Chengming Qin, Guanghui Zhu, Yongxin Zhu, Kai Zhang, Tao Jin, Zhiping Li

    Published 2025-01-01
    “…It is important to study ICE because ICE can help distinguish the species of fusion-product ions, which can also help monitor the fusion alpha ions in large fusion devices, such as CFETR, DEMO, and ITER.…”
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  7. 10627
  8. 10628
  9. 10629

    The role of point-of-care ultrasound in the assessment of schistosomiasis-induced liver fibrosis: A systematic scoping review. by Eloise S Ockenden, Sandrena Ruth Frischer, Huike Cheng, J Alison Noble, Goylette F Chami

    Published 2024-03-01
    “…Over half of all extracted studies (59.4%; 114/192) were conducted in Brazil (26.0%; 50/192), China (18.8%; 36/192) or Egypt (14.6%; 28/192). For the species of schistosome considered, 77.6% (149/192) of studies considered S. mansoni and 21.4% (41/192) of studies considered S. japonicum. …”
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  10. 10630

    Construction of the mathematical model of the strength of post-consumer wood made blockboard of different designs by Serhiy Gayda, Lyubomyr Medvid

    Published 2024-10-01
    “…Sorted and sawn to the appropriate cross-sectional dimensions, strips made from PCW of various species can be used to manufacture glued panel elements, in particular, blockboards and furniture panels. …”
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  11. 10631

    Optogenetic control of horizontally acquired genes prevent stuck fermentations in yeast by David Figueroa, Diego Ruiz, Nicolò Tellini, Matteo De Chiara, Eduardo I. Kessi-Pérez, Claudio Martínez, Gianni Liti, Amparo Querol, José M. Guillamón, Francisco Salinas

    Published 2025-02-01
    “…In Saccharomyces cerevisiae, a genetic segment known as region A, which harbors 12 protein-coding genes, was acquired horizontally from a phylogenetically distant yeast species. This region is mainly present in the genome of wine yeast strains, carrying genes that have been associated with nitrogen utilization. …”
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  12. 10632

    Thermosensitive Porcine Myocardial Extracellular Matrix Hydrogel Coupled with Proanthocyanidins for Cardiac Tissue Engineering by José Luis Hidalgo-Vicelis, Angélica Raquel Rivera-Contreras, Beatriz Hernández-Téllez, Gabriela Piñón-Zárate, Katia Jarquín-Yáñez, Tatiana Fiordelisio-Coll, José Manuel Saniger-Blesa, Gertrudis Hortensia González-Gómez, María Alicia Falcón-Neri, María Margarita Canales-Martínez, Andrés Eliú Castell-Rodríguez

    Published 2025-01-01
    “…Injectable hydrogels are a treatment option because they may replace the damaged extracellular matrix and, in addition, can be administered minimally invasively. Reactive oxygen species generated by ischemia-reperfusion damage can limit the therapeutic efficacy of injectable hydrogels. …”
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  13. 10633

    Emodin protects against severe acute pancreatitis-associated acute lung injury by activating Nrf2/HO-1/GPX4 signal and inhibiting ferroptosis in vivo and in vitro by Gang Shen, Haiyun Wen, Huijuan Li, Xuetao Zhang, Bowen Lan, Xuanchi Dong, Peng Ge, Yalan Luo, Hailong Chen

    Published 2025-02-01
    “…Moreover, these results also showed that EMO, contrary to the effects of ML385, suppressed the ferroptosis response, which manifested as up-regulated glutathione (GSH) and GPX4 levels in vivo and in vitro and down-regulated malondialdehyde (MDA), superoxide dismutase (SOD), Fe2+, and reactive oxygen species (ROS) levels. Conclusions Our results demonstrated that EMO effectively inhibited ferroptosis both in vivo and in vitro, while also modulating the Nrf2/HO-1/GPX4 signaling pathway to provide protection against SAP-ALI.…”
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  14. 10634

    Antimicrobial Activities of Polysaccharide-Rich Extracts from the Irish Seaweed <i>Alaria esculenta</i>, Generated Using Green and Conventional Extraction Technologies, Against Foo... by Ailbhe McGurrin, Rahel Suchintita Das, Arturo B. Soro, Julie Maguire, Noelia Flórez Fernández, Herminia Dominguez, Maria Dolores Torres, Brijesh K. Tiwari, Marco Garcia-Vaquero

    Published 2025-01-01
    “…This study investigates the antimicrobial activity of compounds produced by the Irish seaweed <i>Alaria esculenta</i> against <i>Escherichia coli</i> and <i>Listeria innocua</i>, bacterial species which are relevant for food safety. Microwave-assisted extraction (MAE), ultrasound-assisted extraction (UAE), ultrasound–microwave-assisted extraction (UMAE), and conventional extraction technologies (maceration) were applied to generate extracts from <i>A. esculenta</i>, followed by their preliminary chemical composition (total phenolic content, total protein content, total soluble sugars) and antimicrobial activity (with minimum inhibitory concentration determined by broth microdilution methods), examining also the molecular weight distribution (via high performance size exclusion chromatography) and oligosaccharide fraction composition (via high-performance liquid chromatography) of the polysaccharides, as they were the predominant compounds in these extracts, aiming to elucidate structure–function relationships. …”
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  15. 10635

    Cerium-based nanoplatform for severe acute pancreatitis: Achieving enhanced anti-inflammatory effects through calcium homeostasis restoration and oxidative stress mitigation by Tingyi Luo, Yujing Tang, Wangcheng Xie, Zhilong Ma, Jian Gong, Yonggui Zhang, Tingsong Yang, Xuyang Jia, Jia Zhou, Zhengyu Hu, Lin Han, Qigang Wang, Zhenshun Song

    Published 2025-04-01
    “…Abnormally elevated calcium levels and reactive oxygen species (ROS) overproduction by damaged mitochondria are key factors in the inflammatory cascade in SAP. …”
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  16. 10636

    CMPK2 promotes NLRP3 inflammasome activation via mtDNA‐STING pathway in house dust mite‐induced allergic rhinitis by YaoMing Zheng, YaDong Xie, JiaYing Li, YuJie Cao, Min Li, Qing Cao, MiaoMiao Han, HongFei Lou, YiLai Shu, Hui Xiao, HuaBin Li

    Published 2025-01-01
    “…Additionally, mitochondrial reactive oxygen species (mtROS) production following HDM exposure contributed to mitochondrial dysfunction and the release of mitochondrial DNA (mtDNA), which activated the cyclic GMP‐AMP synthase (cGAS)‐STING pathway. …”
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  17. 10637
  18. 10638

    Genomic adaptation of Clostridium perfringens to human intestine by Ke Wu, Juan Wang, Zelin Yan, Yanyan Zhu, Shaolin Wang, Bo Fu, Chengtao Sun, Ruichao Li, Edward M. Fox, Séamus Fanning, Li Bai, Yang Wang, Yizhi Tang, Zhe Yin, Rong Zhang, Hongning Wang

    Published 2024-12-01
    “…Moreover, we observed that the genomic characteristics of C. perfringens correlate with host species, with specific toxin genes, such as pfoA and colA, potentially influencing host selectivity. …”
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  19. 10639

    Study on the Regulated Cell Death of Hypertrophic H9c2 Cells Induced by Au:Ag Nanoparticles by Galindo-Padrón AG, Lorenzo-Anota HY, Rueda-Munguía M, García-Carrasco A, Gaitán López M, Vázquez-Garza E, Campos-González E, Lozano O, Cholula-Díaz JL

    Published 2025-02-01
    “…Moreover, the effect of the metal-based nanoparticle exposure on healthy and hypertrophic H9c2 cells was measured by analyzing the cellular vitality, the loss of mitochondrial membrane potential (∆Ψm), and the production of mitochondrial reactive oxygen species (mROS).Results: The Au:Ag NPs did not affect the cell vitality of healthy or metabolically activated macrophages. …”
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  20. 10640