The dynamic effects of solar eclipses of October 25, 2022, and October 14, 2023, on GPS-derived total electron content by Vishal Chauhan, Vishakha, Rakesh Singh, Shishupal Singh, Vikram Singh, Om Prakash Singh

“…The time of occurrence of maximum depletion in TEC values at each station is in line with their longitudinal sequence. Atmospheric gravity waves (AGWs) are also observed by performing wavelet analysis on TEC data. …”
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Susceptibility to organophosphate insecticides in Aedes aegypti (Diptera: Culicidae) from northern Colombia and associated resistance mechanisms by María Claudia Atencia-Pineda, Javier García-Leal, Diana Diaz-Ortiz, Paula Pareja-Loaiza, Lisandro Pacheco-Lugo, Richard Hoyos-López, Alfonso Calderón-Rangel, Pedro Fragozo-Castilla, Selene M. Gutiérrez-Rodríguez, Adriana E. Flores, Ronald Maestre-Serrano

“…Additionally, the Ace-1 gene was sequenced to identify mutations at the target site of action. …”
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An MLLM-Assisted Web Crawler Approach for Web Application Fuzzing by Wantong Yang, Enze Wang, Zhiwen Gui, Yuan Zhou, Baosheng Wang, Wei Xie

“…While web crawlers can automatically access and extract critical website information—including form fields and request parameters—which are essential for generating effective fuzzing test cases, current crawler technologies exhibit three primary limitations: (i) insufficient capabilities in analyzing page relationships and determining page states; (ii) lack of functionality-aware exploration capabilities, resulting in generated inputs with poor contextual relevance; (iii) generation of unstructured operation sequences that fail to execute effectively due to their incompatibility with state-based testing logic. …”
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Synthetic integrin antibodies discovered by yeast display reveal αV subunit pairing preferences with β subunits by Yuxin Hao, Jiabin Yan, Courtney Fraser, Aiping Jiang, Murali Anuganti, Roushu Zhang, Kenneth Lloyd, Joseph Jardine, Jessica Coppola, Rob Meijers, Jing Li, Timothy A. Springer

“…Of these, six are function-blocking antibodies and contain a ligand-mimetic R(G/L/T)D motif in their CDR3 sequences. We report antibody-binding specificity, kinetics, and binding affinity for purified integrin ectodomains, as well as intact integrins on the cell surface. …”
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An mRNA-Based Respiratory Syncytial Virus Vaccine Elicits Strong Neutralizing Antibody Responses and Protects Rodents Without Vaccine-Associated Enhanced Respiratory Disease by Jianglong Li, Haiyan Long, Shaoyi Chen, Zhendong Zhang, Shuang Li, Qi Liu, Jun Liu, Jiaru Cai, Liping Luo, Yucai Peng

“…This study aimed to investigate the immunogenicity and efficacy of an mRNA-based RSV vaccine with an F protein sequence. Methods: We designed an mRNA construct encoding a modified RSV F protein, which was further developed into an LNP-encapsulated mRNA vaccine (LVRNA007). …”
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Epigenetic modifications and emerging therapeutic targets in cardiovascular aging and diseases by Yurou Qiu, Qing Xu, Peichen Xie, Chenshuang He, Qiuchan Li, Xin Yao, Yang Mao, Xiaoqian Wu, Tiejun Zhang

“…Epigenetics, which modulates gene expression without DNA sequence changes, is shedding light on these mechanisms and their heritable effects. …”
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Impact of land-use and fecal contamination on Escherichia populations in environmental samples by Adrian L. Cookson, Jonathan C. Marshall, Patrick J. Biggs, Lynn E. Rogers, Rose M. Collis, Megan Devane, Rebecca Stott, Gale Brightwell

“…The resulting amplicons were cross-referenced against a database containing over 700 different partial gnd sequences from E. coli/non-E. coli Escherichia species. …”
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Genomic Variability among Field Isolates and Laboratory-Adapted Strains of Leptospira borgpetersenii Serovar Hardjo by Alejandro Llanes, Carlos Mario Restrepo, Pablo Riesgo-Ferreiro, Sreekumari Rajeev

“…In order to better understand genetic variability among L. borgpetersenii serovar Hardjo isolates, we sequenced and compared the genomes of two laboratory-adapted strains and three abattoir-derived field isolates of L. borgpetersenii serovar Hardjo. …”
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Fluid dynamics of planetary differentiation by Deguen, Renaud, Huguet, Ludovic, Landeau, Maylis, Lherm, Victor, Maller, Augustin, Wacheul, Jean-Baptiste

“…After having summarised the main observational constraints on core-mantle differentiation, the article follows the sequence of processes that led to the formation of planetary cores, focusing on the contributions of laboratory fluid dynamics experiments to our understanding of these processes, and discussing the relevance and limitations of this approach to this problem. …”
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Deformation Characteristics of Existing Twin Tunnels Induced by Double Shield Undercrossing with Prereinforcement: A Case Study in Hangzhou by Xinjiang Wei, Mobao Zhang, Shaojun Ma, Chang Xia, Xingwang Liu, Zhi Ding

“…It was considered that the influence of wall breaking is greater than the sequence of shield undercrossing. The driving parameters of shield tunnelling should be optimized before the second crossing.…”
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Redesigning error control in cross-linking mass spectrometry enables more robust and sensitive protein-protein interaction studies by Boris Bogdanow, Max Ruwolt, Julia Ruta, Lars Mühlberg, Cong Wang, Wen-feng Zeng, Arne Elofsson, Fan Liu

“…Here, we benchmark existing data filtering schemes combined with error rate estimation strategies utilizing concatenated target-decoy protein sequence databases. These workflows show shortcomings either in sensitivity (many false negatives) or specificity (many false positives). …”
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Effects of soy hull polysaccharide on dyslipidemia and pathoglycemia in rats induced by a high-fat-high-sucrose diet by Qian Lin, Lina Yang, Lin Han, Ziyi Wang, Mingshuo Luo, Danshi Zhu, He Liu, Xin Li, Yu Feng

“…After SHP feeding for 4 weeks, the fasting blood glucose (FBG), serum triglyceride (TG), serum high-density lipoprotein cholesterol (HDL-C), short chain fatty acids (SCFAs), and 16S rDNA gene sequence were determined. Administration of SHP significantly decreased body fat content and TG levels, and increased water intake and HDL-C levels after 4 weeks of treatment. …”
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Ion-Selective Electrode for Anionic Surfactants Using Hexadecyl Trimethyl Ammonium Bromide-Sodium Dodecylsulfate as an Active Ionophore by Junwei Wang, Zhiping Du, Wanxu Wang, Wei Xue

“…The electrode shows a selective response to SDS and a poor response to common inorganic anions. The selective sequence found was SDS > HCO3 − > CH3COO− > Cl− > I− > NO3 −≈ Br− > F− > CO3 2− > C6H5O7 3− > C2O4 2− > SO4 2− > C4H4O6 2− > SO3 2− > PO4 3−. …”
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Clustering Pattern and Functional Effect of SNPs in Human miRNA Seed Regions by Sha He, Haiyan Ou, Cunyou Zhao, Jian Zhang

“…miRNAs are a class of noncoding RNAs important in posttranscriptional repressors and involved in the regulation of almost every biological process by base paring with target genes through sequence in their seed regions. Genetic variations in the seed regions have vital effects on gene expression, phenotypic variation, and disease susceptibility in humans. …”
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Functional characterization in Chimonobambusa utilis reveals the role of bHLH gene family in bamboo sheath color variation by Long Tong, Long Tong, Long Tong, Qingping Zeng, Yuan Guo, Yanjie Li, Hongyan Li, Lijie Chen, Xia Liu

“…C. utilis cultivars exhibit five natural color variations in their shoot sheaths, but the molecular mechanism behind this color diversity remains unclear.MethodsDe novo assembly was employed to obtain gene sequences. To identify pathways related to color formation, GO enrichment analysis was performed on the 44,255 functionally annotated unigenes.ResultsThe transcriptomic analysis of C. utilis yielded a total of 195,977 transcripts and 75,137 unigenes after removing redundancy. …”
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Collision-Free Path-Planning for Six-DOF Serial Harvesting Robot Based on Energy Optimal and Artificial Potential Field by Lufeng Luo, Hanjin Wen, Qinghua Lu, Haojie Huang, Weilin Chen, Xiangjun Zou, Chenglin Wang

“…Secondly, the harvesting sequence in path planning was computed by energy optimal method, and the anticollision path points were automatically generated based on the artificial potential field and sampling searching method. …”
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Immune-endocrine crossroads: the impact of nuclear receptors in Tuberculosis and Chagas disease by Ana R. Pérez, Ana R. Pérez, Oscar A. Bottasso, Oscar A. Bottasso, Oscar A. Bottasso, Natalia E. Santucci, Natalia E. Santucci

“…They act as transcription factors and are subclassified into families based on their ligands, DNA-binding sequences, tissue specificity, and functions. Evidence indicates that in infectious diseases, cancer, and autoimmunity, NRs modulate immune and endocrine responses, altering the transcriptional profile of cells and organs and influencing disease progression. …”
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First detection and phylogenetic analysis of Trypanosoma species in European wolves and bears: discovery of novel haplotypes by Blanka Orłowska, Magdalena Świsłocka-Cutter, Katarzyna Filip-Hutsch, Daniel Młocicki, Adam Olszewski, Marek Asman, Krzysztof Anusz, Joanna Werszko

“…The diversity and occurrence of Trypanosoma species among wildlife in Europe were investigated through the analysis of 18S rRNA gene sequences. The phylogenetic analysis showed three new haplotypes of the 18S rRNA gene of Trypanosoma sp. isolated from two grey wolves (Canis lupus) and two brown bears (Ursus arctos). …”
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Structure and formation of the Lower Cretaceous–Eocene section in the central part of the Simferopol Uplift by K.A. Dubkova, S.B. Shishlov, E.M. Bugrova, E.Yu. Zakrevskaya

“…The results obtained show that the Valanginian–Early Hauterivian silty and sandy deltaic deposits of the regressive sedimentation phase are concordantly overlapped by a transgressive sequence formed (from bottom to top) by sandy sediments of the coastal shallows, interlayering middle ramp clayey silts and sands, and outer ramp clays. …”
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Multi-level adaptive coordinated AC fault ride-through control strategy for hybrid cascaded UHVDC transmission system by LYU Yanbei, ZHAO Wenqiang, SHI Qiaoming, YAO Qixin, SUI Shunke, CHANG Haotian

“…Multi-level control strategies, namely controlling the negative sequence voltage of the faulty VSC converter, adopting the auxiliary DC voltage control of the sound VSC converters, switching on the controllable energy dissipation devices at the receiving end and retarding of the LCC converters at the sending end, adjusting the DC power of the converters at the sending and receiving ends, are adaptively coordinated within converters, between converters and between stations to effectively mitigate the overvoltage issues in VSC sub-modules and realize AC fault ride-through of the hybrid cascaded UHVDC system. …”
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