Clinical Implications for the Timely Diagnosis of Mycobacterium marinum in the Age of Biologic Therapy: A Case Report and Review of the Literature by Chris J. Lata, Kelle Edgar, Stephen Vaughan

“…We present a case of a 67-year-old male misdiagnosed with seronegative rheumatoid arthritis presenting with rheumatic nodules. Initiation of chronic immunosuppressant therapy including biologic monoclonal antibodies resulted in the exacerbation of initially localized disease to broadly disseminated lymphatic, joint, and myotendinous granulomatous disease and led to delay in the correct diagnosis. …”
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Recent Advances in ADAM17 Research: A Promising Target for Cancer and Inflammation by Marcia L. Moss, Dmitry Minond

“…ADAM17 inhibitors have broad therapeutic potential, with properties ranging from tumor immunosurveillance and overcoming drug and radiation resistance in cancer, as treatments for cardiac hypertrophy and inflammatory conditions such as inflammatory bowel disease and rheumatoid arthritis. This review focuses on substrates and inhibitors identified more recently for ADAM17 and their role in cancer and inflammation.…”
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Effect of High-Dose Vitamin C Infusion in a Glucose-6-Phosphate Dehydrogenase-Deficient Patient by Joseph Quinn, Bryan Gerber, Ryan Fouche, Katharine Kenyon, Zachary Blom, Purushothaman Muthukanagaraj

“…We present a case of hemolysis in a glucose-6-phosphate dehydrogenase- (G6PD-) deficient patient receiving high-dose vitamin C infusions for his rheumatoid arthritis.…”
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Role of high-density lipoprotein cholesterol in health and diseases by Brijesh Yadav, Narayan Prasad

“…In this review, we have discussed the different property of high-density lipoprotein cholesterol, its function and factors influencing HDLc property in light of anti-inflammatory activity in rheumatoid arthritis and the role of cholesterol-lowering statin drug in enhancing the beneficial effect of high-density lipoprotein cholesterol in different cell types.…”
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Complete Remission of Methotrexate-Related Epstein-Barr-Virus-Associated Hodgkin-Like Lymphoma following Withdrawal of MTX Coupled with Clarithromycin Administration by Nobuo Takemori, Hiroyuki Kaneko, Masaya Nakamura, Masaru Kojima

“…Patients with rheumatoid arthritis (RA) are known to develop lymphoproliferative disorders (LPDs) during the course of illness, particularly in cases treated with methotrexate (MTX) for long periods. …”
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Peripheral Ulcerative Keratitis Associated with Autoimmune Disease: Pathogenesis and Treatment by Yan Cao, Wensong Zhang, Jie Wu, Hong Zhang, Hongyan Zhou

“…PUK may have a connection to systemic conditions, such as long-standing rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), Wegener granulomatosis (WG), relapsing polychondritis, classic polyarteritis nodosa and its variants, microscopic polyangiitis, and Churg-Strauss syndrome. …”
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Long Term Safety of Infliximab by Thomas F Schaible

“…Infliximab is a chimeric anti-tumour necrosis factor-alpha monoclonal antibody that has been studied for the treatment of Crohn’s disease and rheumatoid arthritis. In several placebo controlled, randomized clinical trials and open trials, 771 patients have been given infliximab (a further 192 received placebo). …”
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Rheumatoid Meningoencephalitis: A Feared Condition in the Era of TNF Blockers by Fernando Figueroa Rodriguez, Kwon Minkyung, Sruthi Jinna, Sohail Farshad, Francisco Davila

“…Central nervous system (CNS) involvement in rheumatoid arthritis (RA) is uncommon, and most of the times, it is secondary to vasculitic processes or extra-articular rheumatoid nodules. …”
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Multicentric Reticulohistiocytosis Presenting with Papulonodular Skin Lesions and Arthritis Mutilans by Raya Saba, Shawn G. Kwatra, Bishwas Upadhyay, Aibek E. Mirrakhimov, Farah N. Khan

“…We report the case of a 54-year-old female who was misdiagnosed as having rheumatoid arthritis and underwent numerous joint replacement surgeries for progressively destructive arthritis in her hands, shoulders, hips, and knees. …”
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A Rapidly Fatal Case of Low-Dose Methotrexate Toxicity by Nasreen Shaikh, Muhammad Sardar, Rishi Raj, Punit Jariwala

“…She had history of rheumatoid arthritis for which she was taking 7.5 mg methotrexate weekly and stage 4 chronic kidney disease from diabetic nephropathy. …”
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Comprehensive management application of sulodexide on proteinuria: 2 case reports by Li Zhou, Wenge Li

“…Case 2 is a 52 years-old female with chronic nephritis and rheumatoid arthritis accompanied by persistent proteinuria and edema in both legs. …”
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Machine Learning Techniques for Quantification of Knee Segmentation from MRI by Sujeet More, Jimmy Singla, Ahed Abugabah, Ahmad Ali AlZubi

“…Moreover, for the detailed diagnosis of varied diseases such as knee rheumatoid arthritis (RA), segmentation of the knee magnetic resonance image is a challenging and complex task that has been explored broadly. …”
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Cytokine Reduction in the Treatment of Joint Conditions by J. D. Sipe, J. Martel-Pelletier, I. G. Otterness, J.-P. Pelletier

“…The destruction of joints caused by rheumatoid arthritis and osteoarthritis is characterized by an imbalance of enzyme catalysed cartilage breakdown and regeneration. …”
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Bilateral Stress Fractures of the Femoral Neck after Total Knee Arthroplasty: Importance of Early Diagnosis by Sei Morinaga, Kenichi Ueshima, Yoshinobu Maruhashi, Noriyuki Hashimoto, Shoji Watanabe, Takuya Nakamura

“…We report a patient suffering from rheumatoid arthritis of both knees, who was treated with bilateral TKA. …”
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Exploring the Safety and Effects of COVID-19 Vaccination in Patients with Autoimmune Disease by Kirttna Solai Vairavan, Loh Teng-Hern Tan, Jodi Woan Fei Law, Priyia Pusparajah, Vengadesh Letchumanan

“…The search results were limited to 4 distinct autoimmune diseases (rheumatoid arthritis, systemic lupus erythematosus, psoriasis, and myasthenia gravis). …”
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Adalimumab (TNFα Inhibitor) Therapy Exacerbates IgA Glomerulonephritis Acute Renal Injury and Induces Lupus Autoantibodies in a Psoriasis Patient by S. S. Wei, R. Sinniah

“…Adalimumab (Humira) is a tumour necrosis factor α (TNFα) inhibitor that is approved for the treatment of rheumatoid arthritis, psoriasis, psoriatic arthritis, Crohn's disease, ankylosing spondylitis, and juvenile idiopathic arthritis (Sullivan and Preda (2009), Klinkhoff (2004), and Medicare Australia). …”
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Therapeutic implications for the PD-1 axis in cerebrovascular injury by James Feghali, Christopher M. Jackson

“…PD-1 agonism has already demonstrated success in clinical trials for rheumatoid arthritis and is being tested in other chronic inflammatory diseases. …”
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Immunometabolism of Tregs: mechanisms, adaptability, and therapeutic implications in diseases by Yuming Lu, Yifan Wang, Tiantian Ruan, Yihan Wang, Linling Ju, Mengya Zhou, Luyin Liu, Dengfu Yao, Min Yao

“…The complex mechanisms of Tregs in metabolic diseases are intriguing, particularly in conditions like MASLD, where Tregs are significantly upregulated and contribute to fibrosis, while in diabetes, systemic lupus erythematosus (SLE), and rheumatoid arthritis (RA), they show downregulation and reduced anti-inflammatory capacity. …”
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Rare Case Studies of Bilateral and Symmetric Sacroiliac Disease by Stephen Soloway, Alyxandra M. Soloway, Tyler G. Chin, Timothy Lieske

“…We present three rare conditions presenting with bilateral and symmetric SIJ disease, none of which is ankylosing spondylitis, Crohn’s colitis, ulcerative colitis, psoriatic arthritis, and reactive arthritis (Reiter syndrome); there are reports of concurrent SIJ disease in rheumatoid arthritis and SLE. Conclusion. The authors believe that SIJ disease is overlooked, is underdiagnosed, and can lead to incorrect treatment. …”
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Patellar Tendon Rupture after Lateral Release without Predisposing Systemic Disease or Steroid Use by S. De Giorgi, A. Notarnicola, G. Vicenti, B. Moretti

“…Nevertheless, in case of systemic diseases (LES, rheumatoid arthritis, and chronic renal insufficiency) that can weaken collagen structures, bilateral patellar tendon ruptures are described. …”
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