Biological rhythms of the liver by Anatol Panasiuk, Mirosław Tarasewicz, Albert Chodowiec, Anna Łokić, Kacper Gan

“…The central clock is located in the suprachiasmatic nucleus (SCN) of the hypothalamus and is regulated by signals received from the retinal pathway. The SCN regulates the circadian rhythm of the entire body through its indirect influence on the peripheral clocks. …”
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NLRP3 Inflammasome: Activation and Regulation in Age-Related Macular Degeneration by Jiangyuan Gao, Ruozhou Tom Liu, Sijia Cao, Jing Z. Cui, Aikun Wang, Eleanor To, Joanne A. Matsubara

“…Progression of AMD is characterized by an increase in the number and size of drusen, extracellular deposits, which accumulate between the retinal pigment epithelium (RPE) and Bruch’s membrane (BM) in outer retina. …”
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Structural insights into light-gating of potassium-selective channelrhodopsin by Takefumi Morizumi, Kyumhyuk Kim, Hai Li, Probal Nag, Tal Dogon, Oleg A. Sineshchekov, Yumei Wang, Leonid S. Brown, Songhwan Hwang, Han Sun, Ana-Nicoleta Bondar, Igor Schapiro, Elena G. Govorunova, John L. Spudich, Oliver P. Ernst

“…Upon photoisomerization of the retinal chromophore, the retinylidene Schiff base NH-bond reorients from the extracellular to the cytoplasmic side. …”
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Drive slow, craters everywhere: A rare presentation of double macular coloboma with contralateral optic disc coloboma by Avik Dey Sarkar, Muthukrishnan Vallinayagam, Naresh Babu Kannan, Tanya Balakrishnan

“…On dilated fundoscopy, in OD, a large, deep hole with sharp borders on the temporal edge of the optic disc without any retinal tissue herniation was noted, while in OS, two large sharply demarcated excavations near the inferior arcade were evident. …”
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Widefield Optical Coherence Tomography Angiography in Diabetic Retinopathy by Alessia Amato, Francesco Nadin, Federico Borghesan, Maria Vittoria Cicinelli, Irini Chatziralli, Saena Sadiq, Rukhsana Mirza, Francesco Bandello

“…WF-OCTA harbors interesting potential in DR because of its noninvasiveness and capability of objective metrics of retinal vasculature. Further studies will facilitate the migration from traditional imaging to WF-OCTA in both the research and clinical practice fields.…”
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Behçet's Disease (Adamantiades-Behçet's Disease) by Fumio Kaneko, Ari Togashi, Sanae Saito, Hideo Sakuma, Noritaka Oyama, Koichiro Nakamura, Kenji Yokota, Keiji Oguma

“…Bes-1 gene encoded partial S. sanguinis genome which is highly homologous with retinal protein, and 65 kD heat shock protein (Hsp-65) released from streptococci is playing an important role with human Hsp-60 in the pathogenesis of ABD. …”
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Aspergillus fumigatus Endophthalmitis with Necrotizing Scleritis following Pars Plana Vitrectomy by Anna M. Gruener, Felicity Allen, Miles R. Stanford, Elizabeth M. Graham

“…We present a case of Aspergillus fumigatus endophthalmitis complicated by necrotizing scleritis in a 68-year-old man with diet-controlled diabetes, after retinal detachment repair. He was initially treated with systemic steroids for surgically induced necrotizing scleritis following routine pars plana vitrectomy. …”
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Bilateral Ampiginous Choroiditis following Presumed SARS-CoV-2 Infection by Elysse S. Tom, K. Matthew McKay, Steven S. Saraf

“…She was treated with oral prednisone and azathioprine with stabilization of the retinal lesions and no progression of her symptoms. …”
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Embolic Stroke as the Initial Manifestation of Systemic Lupus Erythematosus by Reshma M. Khan, Rajaie Namas, Sachin Parikh, Bernard Rubin

“…Ophthalmology evaluation revealed bilateral retinal artery occlusion. Further workup with imaging of the brain was consistent with an ischemic stroke. …”
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Endoscopic Vitrectomy Combined with 3D Heads-Up Viewing System in Treating Traumatic Ocular Injury by Yuan-Shao Cheng, Chung-Hao Hsiao, Wei-Ping Hsia, Hung-Ju Chen, Chia-Jen Chang

“…No subject suffered from retinal detachment, endophthalmitis, or other severe complications. …”
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Photopsias during Systemic Bevacizumab Therapy by Heather Leisy, Meleha Ahmad, R. Theodore Smith

“…We propose that patients who undergo intravenous bevacizumab treatments are questioned for any ocular symptoms and that more systematic evaluations of retinal nerve fiber layer and choroidal effects are obtained in those patients who are on long-term treatment at high doses.…”
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Angularly Resolved Deep Brain Fluorescence Imaging Using a Single Optical Fiber by Israel J. De La Rosa, Mehdi Azimipour, Patrick K. Cullen, Fred J. Helmstetter, Ramin Pashaie

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Leber's Hereditary Optic Neuropathy-Gene Therapy: From Benchtop to Bedside by Rajeshwari D. Koilkonda, John Guy

“…While the mutated mtDNA impairs generation of ATP by all mitochondria, there is only a selective loss of retinal ganglion cells and degeneration of optic nerve axons. …”
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Animal Models of Diabetic Retinopathy: Summary and Comparison by Angela Ka Wai Lai, Amy C. Y. Lo

“…Although clinical assessment and retinal autopsy of diabetic patients provide information on the features and progression of DR, its underlying pathophysiological mechanism cannot be deduced. …”
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Bevacizumab Injection in Patients with Age-Related Macular Degeneration Associated with Poor Initial Visual Acuity by Leila El Matri, Rym Bouraoui, Ahmed Chebil, Fedra Kort, Mejda Bouladi, Rym Limaiem, Hana Landoulsi

“…Mean baseline central retinal thickness was 431 μm ±159.7 at 6 months was 293.43 μm  ±122.79 (𝑃=10−4) and at 12 months was 293.1 μm  ±130 (𝑃=0.004). …”
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Phospho-seq: integrated, multi-modal profiling of intracellular protein dynamics in single cells by John D. Blair, Austin Hartman, Fides Zenk, Philipp Wahle, Giovanna Brancati, Carol Dalgarno, Barbara Treutlein, Rahul Satija

“…We apply our workflow to cell lines, induced pluripotent stem cells, and months-old retinal and brain organoids to demonstrate its broad applicability. …”
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Microelectrothermoforming (μETF): one-step versatile 3D shaping of flexible microelectronics for enhanced neural interfaces by Dong Hyeon Lee, Younghoon Park, Yoon Seo, Hannah Noh, Hyunbeen Jeong, Jongmo Seo, Min-Ho Seo, Kyungsik Eom, Joonsoo Jeong

“…The benefits of 3D MEA are evaluated in retinal stimulation through numerical simulations and ex vivo experiments, confirming a threshold lowered by 1.7 times and spatial resolution enhanced by 2.2 times.…”
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Decreased Perifoveal Sensitivity Detected by Microperimetry in Patients Using Hydroxychloroquine and without Visual Field and Fundoscopic Anomalies by A. Molina-Martín, D. P. Piñero, R. J. Pérez-Cambrodí

“…Microperimetry seems to be a useful tool for the early detection of retinal damage in patients treated with hydroxychloroquine.…”
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Underlying anti-hypertensive mechanism of the Mizuhopecten yessoensis derived peptide NCW in spontaneously hypertensive rats via widely targeted kidney metabolomics by Wenjun Xue, Wenzhu Zhao, Sijia Wu, Zhipeng Yu

“…The peptide NCW might regulate kidney metabolic disorder of SHRs to alleviate hypertension by suppressing inflammation and improving nitric oxide production under the regulation of linoleic acid metabolism, folate related pathways, synthesis and degradation of ketone bodies, pyrimidine metabolism, β-alanine metabolism, and retinal metabolism.…”
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Preoperative Inflammatory Control and Surgical Outcome of Vitrectomy in Intermediate Uveitis by Yong Un Shin, Joo Young Shin, Dae Joong Ma, Heeyoon Cho, Hyeong Gon Yu

“…The indications of vitrectomy included epiretinal membrane (26 eyes), vitreous opacity (21 eyes), and tractional retinal detachment (12 eyes), among others. Uveitic attacks did not occur in 44 of the 66 patients after vitrectomy. …”
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