In silico study about β-amyloid’s role in Alzheimer’s disease and glaucoma and prediction of its interactions with glaucoma related proteins by Nancy Maurya

“…This study is an attempt to evaluate the chances of β-amyloid’s role in pathogenesis of retinal neurodegenerative disorder called glaucoma, in silico. …”
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3D Curvelet-Based Segmentation and Quantification of Drusen in Optical Coherence Tomography Images by M. Esmaeili, A. M. Dehnavi, H. Rabbani

“…Spectral-Domain Optical Coherence Tomography (SD-OCT) is a widely used interferometric diagnostic technique in ophthalmology that provides novel in vivo information of depth-resolved inner and outer retinal structures. This imaging modality can assist clinicians in monitoring the progression of Age-related Macular Degeneration (AMD) by providing high-resolution visualization of drusen. …”
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Selective retina therapy with real-time feedback-controlled technology in central serous chorioretinopathy: a 24-month follow-up real-world prospective study by Hyeong Gon Yu, Chang Ki Yoon

“…The mean best-corrected visual acuity (BCVA; logarithm of the minimum angle of resolution, mean±SD) improved slightly from 0.15±0.18 at baseline to 0.12±0.21 at 6 months (p=0.062). The central retinal thickness (CRT; mean±SD) was reduced significantly from 350.6±100.1 µm at baseline to 268.2±70.6 µm at 6 months (p<0.001). …”
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An Ensemble Based Machine Learning Classification for Automated Glaucoma Detection by Digvijay J. Pawar, Yuvraj K. Kanse, Suhas S. Patil

“…This paper has proposed an approach for effectively extracting the key features of colour retinal fundus images and categorizing them as normal or glaucomatous. …”
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Causes and Risk Factors of Repeated Hospitalization among Patients with Diabetic Retinopathy by Yu Xiao, Yingying Liang, Zhanjie Lin, Huiqian Kong, Zijing Du, Yunyan Hu, Shuyi Ouyang

“…Furthermore, patients readmitted for vitreous hemorrhage, proliferative membrane formation, and retinal detachment experienced longer length of hospital stay and higher hospitalization cost (p<0.001). …”
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Anesthesia for Pars Plana Vitrectomy with Insulin Needle, Is It Possible? by Waleed Riad, Nauman Ahmed, Emad Abboud, Essam Al-Harthi, Eman Kahtani

“…Peribulbar block with 12.5 mm needle together with digital compression is a suitable alternative to the standard block with 25 mm needle length for retinal surgery.…”
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The role of optical coherence tomography angiography in assessing diabetic choroidopathy: a systematic review by M. Hossein Nowroozzadeh, Mansoureh Bagheri

“…Results OCTA allows for non-invasive, high-resolution visualization of retinal and choroidal microvasculature, providing both qualitative and quantitative data. …”
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Update on the Treatment of Diabetic Retinopathy by Jennifer L. Wilkinson-Berka, Antonia G. Miller

“…Vision loss from diabetes is due to a number of factors, including haemorrhage from new and poorly formed blood vessels, retinal detachment due to contraction of deposited fibrous tissue, and neovascular glaucoma resulting in an increase in intraocular pressure. …”
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Unilateral focal choroidal excavation in autosomal recessive bestrophinopathy by Neha Goel

“…ARB is a rare inherited retinal dystrophy resulting from mutations in the BEST1 gene. …”
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Intrasurgical Imaging of Subinternal Limiting Membrane Blood Diffusion in Terson Syndrome by Lorenzo Iuliano, Giovanni Fogliato, Marco Codenotti

“…Here we hypothesize that the subretinal space might be unlikely to be a primary source of intraocular hemorrhage, and we support the two generally accepted theories about blood diffusion from the retinal vasculature or from the perivascular spaces.…”
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Long-Term Treatment Outcomes of Micropulse Transscleral Cyclophotocoagulation in Primary and Secondary Glaucoma: A 5-Year Analysis by Ronald M. P. C. de Crom, Stefani Kujovic-Aleksov, Carroll A. B. Webers, Tos T. J. M. Berendschot, Henny J. M. Beckers

“…Other adverse events were retinal venous occlusion (n = 1) and retinal vasculitis (n = 1), unrelated to the laser treatment. …”
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Characterization of NGF, trkANGFR, and p75NTR in Retina of Mice Lacking Reelin Glycoprotein by Bijorn Omar Balzamino, Filippo Biamonte, Graziana Esposito, Ramona Marino, Francesca Fanelli, Flavio Keller, Alessandra Micera

“…Both Reelin and Nerve Growth Factor (NGF) exert crucial roles in retinal development. Retinogenesis is severely impaired in E-reeler mice, a model of Reelin deficiency showing specific Green Fluorescent Protein expression in Rod Bipolar Cells (RBCs). …”
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High-Mobility Group Box-1 Induces Decreased Brain-Derived Neurotrophic Factor-Mediated Neuroprotection in the Diabetic Retina by Ahmed M. Abu El-Asrar, Mohd Imtiaz Nawaz, Mohammad Mairaj Siddiquei, Abdullah S. Al-Kharashi, Dustan Kangave, Ghulam Mohammad

“…Our results suggest that HMGB1-induced downregulation of BDNF might be involved in pathogenesis of diabetic retinal neurodegeneration.…”
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Comparison of optical coherence tomography vs. fluorescein angiography-based macular neovascularization classifications in age-related macular degeneration by Gábor G. Deák, Klaudia Birner, Bianca S. Gerendas, Georgios Mylonas, Günther Weigert, Martin Michl, Irene Steiner, Ursula M. Schmidt-Erfurth

“…Using a validated AI tool (RetInSight Fluid Monitor Version 2), we localized and quantified retinal fluid. Kappa coefficients for agreement between FA and OCT MNV types were 0.58 [0.52; 0.64] (type 1/occult), 0.46 [0.38; 0.55] (type 2/classic), and 0.53 [0.44; 0.62] (type 3/RAP). …”
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Targeting Endothelial Adhesion Molecule Transcription for Treatment of Inflammatory Disease: A Proof-of-Concept Study by Liam M. Ashander, Binoy Appukuttan, Yuefang Ma, Dione Gardner-Stephen, Justine R. Smith

“…Intercellular adhesion molecule 1 (ICAM-1) mediates leukocyte migration across the retinal endothelium in noninfectious posterior uveitis. …”
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Associations between choroidal thickness and rate of axial elongation in orthokeratology lens users by Riping Zhang, Suoqing Zhuang, Youming Zhou, Man Pan Chin, Lixia Sun, Vishal Jhanji, Mingzhi Zhang

“…Objective: To investigate the impact of using orthokeratology lenses (OK lenses) for one year on the axial length (AL) and choroidal thickness (ChT) in the 6 mm concentric central retinal region. Methods: 36 myopic children (36 eyes) aged 8 to 16 years were enrolled. …”
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An exploratory study to evaluate efficacy and safety of frequent Transcutaneous Electrical Stimulation for Leber Hereditary Optic Neuropathy by Fumio Takano, Kaori Ueda, Takuji Kurimoto, Mina Arai, Takayuki Nagai, Yuko Yamada-Nakanishi, Makoto Nakamura

“…Abstract Electrical stimulation (ES) may be effective for intractable retinal or optic nerve diseases. We studied frequent transcutaneous ES in a single-center, single-arm prospective study in patients with Leber hereditary optic neuropathy (LHON) who carry the mitochondrial (mt) 11778 G > A mutation. …”
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Altered Expression of NF-κB and SP1 after Exposure to Advanced Glycation End-Products and Effects of Neurotrophic Factors in AGEs Exposed Rat Retinas by Guzel Bikbova, Toshiyuki Oshitari, Takayuki Baba, Shuichi Yamamoto

“…These results demonstrate the potential of the NTFs as axoprotectants in AGEs exposed retinal neurons.…”
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Scutellarin Prevents Angiogenesis in Diabetic Retinopathy by Downregulating VEGF/ERK/FAK/Src Pathway Signaling by Lingli Long, Yubin Li, Shuang Yu, Xiang Li, Yue Hu, Tengfei Long, Liqin Wang, Wenwen Li, Xiaoxin Ye, Zunfu Ke, Haipeng Xiao

“…This study demonstrates the antiangiogenic effects of scutellarin (SCU) on high glucose- and hypoxia-stimulated human retinal endothelial cells (HRECs) and on a diabetic rat model by oral administration. …”
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Pronerve Growth Factor Induces Angiogenesis via Activation of TrkA: Possible Role in Proliferative Diabetic Retinopathy by Sally L. Elshaer, Mohammed A. Abdelsaid, Ahmad Al-Azayzih, Parag Kumar, Suraporn Matragoon, Julian J. Nussbaum, Azza B. El-Remessy

“…The angiogenic response of aqueous humor samples from PDR patients was examined in human retinal endothelial cells in the presence or absence of anti-proNGF antibody. …”
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