Comparison of Progression Rate of Retinal Pigment Epithelium Loss in Patients with Neovascular Age-Related Macular Degeneration Treated with Ranibizumab and Aflibercept by Juliana Wons, Magdalena A. Wirth, Nicole Graf, Matthias D. Becker, Stephan Michels

“…Purpose. Retinal pigment epithelium (RPE) loss in neovascular age-related macular degeneration (nAMD) seem to have a linear progression but might be influenced by the treatment. …”
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Is the Retinal Vasculature Related to β-Peripapillary Atrophy in Nonpathological High Myopia?... by Jiao Sun, Jialin Wang, Ran You, Yanling Wang

“…The association between β-peripapillary atrophy and the retinal vasculature in nonpathological high myopia is unclear. …”
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iPSC-Derived Retinal Pigment Epithelium Allografts Do Not Elicit Detrimental Effects in Rats: A Follow-Up Study by Peter D. Westenskow, Felicitas Bucher, Stephen Bravo, Toshihide Kurihara, Daniel Feitelberg, Liliana P. Paris, Edith Aguilar, Jonathan H. Lin, Martin Friedlander

“…Phototransduction is accomplished in the retina by photoreceptor neurons and retinal pigment epithelium (RPE) cells. Photoreceptors rely heavily on the RPE, and death or dysfunction of RPE is characteristic of age-related macular degeneration (AMD), a very common neurodegenerative disease for which no cure exists. …”
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Automatic Detection and Classification of Eye Diseases from Retinal Images Using Deep Learning: A Comprehensive Research on the ODIR Dataset by Asadi Srinivasulu, Clement Varaprasad Karu, G Sreenivasulu, Gayathri R

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Switch of Intravitreal Therapy for Macular Edema Secondary to Retinal Vein Occlusion from Anti-VEGF to Dexamethasone Implant and Vice Versa by Amelie Pielen, Anima Desiree Bühler, Sonja Ute Heinzelmann, Daniel Böhringer, Thomas Ness, Bernd Junker

“…To evaluate the anatomical and functional outcome of intravitreal dexamethasone implant for macular edema secondary to central (C) or branch (B) retinal vein occlusion (RVO) in patients with persistent macular edema (ME) refractory to intravitreal antivascular endothelial growth factor (VEGF) treatment compared to treatment naïve patients and to dexamethasone-refractory eyes switched to anti-VEGF. …”
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New proposal for a multimodal imaging approach for the subclinical detection of hydroxychloroquine-induced retinal toxicity in patients with systemic lupus erythematosus by Ricard Cervera, Alfredo Adan, Gerard Espinosa, Jose Rios, Olga Araujo, José Hernández-Rodríguez, Laura Pelegrín, Ricardo P Casaroli-Marano, Halbert Hernández-Negrín, Marc Figueras-Roca, Vanesa Budi, Montse Morató

“…Four (6.1%) patients developed subclinical hydroxychloroquine-induced retinal toxicity without visual acuity impairment. …”
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Application of optical coherence tomography angiography to study retinal and choroidal vascular changes in patients with first-time coronary artery stenosis by Rongrong Guan, Shuyan Qin, Yezhu Chi, Zhen Tang, Haiyang Liu

“…Objective: To study the changes in retinal and choroidal vessels in patients with coronary artery stenosis via optical coherence tomography angiography (OCTA). …”
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Protocol for real-time assessment of energy metabolism in dissociated mouse retinal photoreceptors using a SeahorseXFe24 analyzer by Maria Yera, Joshua J. Wang, Sarah X. Zhang

“…Summary: Defects in retinal metabolism have been linked to the onset and progression of various retinal diseases. …”
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Retinal Ganglion Cell Atrophy in Homonymous Hemianopia due to Acquired Occipital Lesions Observed Using Cirrus High-Definition-OCT by Tsutomu Yamashita, Atsushi Miki, Katsutoshi Goto, Syunsuke Araki, Go Takizawa, Yoshiaki Ieki, Junichi Kiryu, Akio Tabuchi, Yasuyuki Iguchi, Kazumi Kimura, Yoshiki Yagita

“…Also, it is suggested that the retinal changes observed are progressive.…”
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Prediction of Causative Genes in Inherited Retinal Disorders from Spectral-Domain Optical Coherence Tomography Utilizing Deep Learning Techniques by Yu Fujinami-Yokokawa, Nikolas Pontikos, Lizhu Yang, Kazushige Tsunoda, Kazutoshi Yoshitake, Takeshi Iwata, Hiroaki Miyata, Kaoru Fujinami, on behalf of Japan Eye Genetics Consortium

“…To illustrate a data-driven deep learning approach to predicting the gene responsible for the inherited retinal disorder (IRD) in macular dystrophy caused by ABCA4 and RP1L1 gene aberration in comparison with retinitis pigmentosa caused by EYS gene aberration and normal subjects. …”
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Propensity Score to Compare Pars Plana Vitrectomy and Scleral Buckling in Retrospective Studies [Letter] by Visioli G, Alisi L, Albanese GM

Subjects: “…rhegmatogenous retinal detachment…”
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Intraocular inflammation after intravitreal injection of aflibercept 8 mg for treatment-refractory neovascular age-related macular degeneration: a case report by Nozomu Hashiya, Ichiro Maruko, Yuri Miyaguchi, Ruka Maruko, Taiji Hasegawa, Tomohiro Iida

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Quantification of Macular Vascular Density Using Optical Coherence Tomography Angiography and Its Relationship with Retinal Thickness in Myopic Eyes of Young Adults by Shiqi Yang, Minwen Zhou, Bing Lu, Pengfei Zhang, Jingke Zhao, Mei Kang, Ruoshi Wang, Fenghua Wang, Xiaodong Sun

“…To quantify macular vascular density using optical coherence tomography angiography (OCTA) and to investigate its relationship with retinal thickness in myopic eyes of young adults. …”
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Effect of Vitreous Reflux after Intravitreal Aflibercept Injection for Macular Edema with Branch Retinal Vein Occlusion: A Real-World Study by Tetsuya Muto, Masaaki Sakamoto, Shigeki Machida, Shinichiro Imaizumi, Tetsuju Sekiryu

“…The treatment response was evaluated with the best-corrected visual acuity (BCVA) and optical coherence tomography measurements of the retinal foveal thickness (RFT) before treatment and 1 month after the first injection. …”
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Silicone Oil Reinjection without Macular Buckling for Treatment of Recurrent Myopic Macular Hole Retinal Detachment after Silicone Oil Removal by Hammouda Hamdy Ghoraba, Sameh Mohamed Elgouhary, Hosam Osman Mansour

“…The main outcomes were the retinal status after silicone oil removal and management of recurrent cases. …”
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Combined Left Central Retinal Artery Occlusion and Bilateral Anterior Ischemic Optic Neuritis: A Rare Presentation of Giant Cell Arteritis by Anne D. D. Joseph, Jebananthy Anandaselvam Pradeepan, Thirunavukarasu Kumanan, Muthusamy Malaravan

“…We hereby report a case of combined left central retinal artery occlusion and bilateral anterior ischemic optic neuritis in a patient who poorly responded to standard corticosteroid therapy.…”
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Outcomes of Vitrectomy Combined with Scleral Buckling for Eyes with Early Recurrence of Simple Rhegmatogenous Retinal Detachment Previously Treated by Pars Plana Vitrectomy by Tomoaki Tatsumi, Takayuki Baba, Takehito Iwase, Tomohiro Nizawa, Gen Miura, Hirotaka Yokouchi, Shuichi Yamamoto

“…The reattachment of an early recurrent retinal detachment by PPV with SB is effective.…”
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A Propensity-Score Matching Comparison between 27-Gauge and 25-Gauge Vitrectomy Systems for the Repair of Primary Rhegmatogenous Retinal Detachment by Daniele Veritti, Valentina Sarao, Paolo Lanzetta

“…To compare the anatomical and visual results and complications of 27-gauge versus 25-gauge transconjunctival sutureless vitrectomy for the management of primary rhegmatogenous retinal detachment. Methods. A prospective, propensity score-matched 6-month study was performed. …”
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Sub-Clinical Regional Macular Changes in Self-Reported Diabetic Subjects: Vascular and Retinal Layer Analysis Using Swept-Source OCT by Challa NK, Alghamdi WM, Alluwimi MS, Alshammeri S

“…There was also significant thinning of the superior macular retinal nerve fiber layer (RNFL) in diabetics compared to controls (P = 0.02). …”
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Insights and Considerations for “Higher Intraocular Levels of Inflammatory Factors Are Related to Retinal Vascular and Neurodegeneration in Myopic Retinopathy” [Response to Letter] by Zeng L, Yang Z, Li X, Xu H

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