Branch retinal artery occlusion and spontaneous vitreous hemorrhage in cavernous hemangioma of the optic disc: A rare case report by Ketan Jathar, Gunjan Singh, Shalaka Pissurlencar

“…Retinal cavernous hemangioma is a rare benign tumor. …”
Get full text

Revealing speckle obscured living human retinal cells with artificial intelligence assisted adaptive optics optical coherence tomography by Vineeta Das, Furu Zhang, Andrew J. Bower, Joanne Li, Tao Liu, Nancy Aguilera, Bruno Alvisio, Zhuolin Liu, Daniel X. Hammer, Johnny Tam

“…Abstract Background In vivo imaging of the human retina using adaptive optics optical coherence tomography (AO-OCT) has transformed medical imaging by enabling visualization of 3D retinal structures at cellular-scale resolution, including the retinal pigment epithelial (RPE) cells, which are essential for maintaining visual function. …”
Get full text

Predicting branch retinal vein occlusion development using multimodal deep learning and pre-onset fundus hemisection images by Eun Young Choi, Dongyoung Kim, Jinyeong Kim, Eunjin Kim, Hyunseo Lee, Jinyoung Yeo, Tae Keun Yoo, Min Kim

Subjects: “…Branch retinal vein occlusion…”
Get full text

Time-Domain and Spectral-Domain Optical Coherence Tomography of Retinal Nerve Fiber Layer in MS Patients and Healthy Controls by Alex P. Lange, Reza Sadjadi, Jameelah Saeedi, Janette Lindley, Fiona Costello, Anthony L. Traboulsee

“…The aim of this study was to compare retinal nerve fiber layer thickness (RNFLT) between spectral-domain (SD-) and time-domain optical coherence tomography (TD-OCT) in MS patients and healthy controls (HC). …”
Get full text

Effect of Ripasudil on the Change Rates of the Circumpapillary Retinal Nerve Fiber Layer Thickness in Patients With Primary Open-Angle Glaucoma by Katsumasa Sakurai, Kenji Suda, Tadamichi Akagi, Hanako Ohashi Ikeda, Takanori Kameda, Masahiro Miyake, Tomoko Hasegawa, Akitaka Tsujikawa

Get full text

An Efficient Retinal Fluid Segmentation Network Based on Large Receptive Field Context Capture for Optical Coherence Tomography Images by Hang Qi, Weijiang Wang, Hua Dang, Yueyang Chen, Minli Jia, Xiaohua Wang

Subjects: Get full text

A Novel Pathogenic Splicing Mutation of OFD1 is Responsible for a Boy with Joubert Syndrome Exhibiting Orofaciodigital Spectrum Anomalies, Polydactyly and Retinitis Pigmentosa by Chen L, Zhao MF, Deng HW, Liao M, Fan LL, Zhong QB, Wang J, Li K, Wu ZH, Yin JY

“…Here, we identified a child who presented with Joubert syndrome exhibiting orofaciodigital spectrum anomalies, polydactyly, and retinitis pigmentosa. Whole exome sequencing and Sanger sequencing revealed a splicing mutation (NM_003611.2, c.2387+1G>A) in the OFD1 gene of the patient and his mother. mRNA sequencing further confirmed this mutation. …”
Get full text

Neovascular Glaucoma as the First Symptom of Bilateral Occlusive Retinal Vasculitis in a 4-Year-Old Girl: A Case Report by Klaudia Rakusiewicz-Krasnodębska, Joanna Jędrzejczak-Młodziejewska, Krystyna Kanigowska, Wojciech Hautz

Subjects: Get full text

Long-Term Follow-Up Results of a Patient Undergoing Acute Retinal Necrosis: A Case Report and Literature Review by Büşra Köse, Hidayet Erdöl, Dilek Uzlu

“…To describe the follow-up and treatment approach of a patient with acute retinal necrosis. Case Report. A 44-year-old male patient, who had complaints of pain in the right eye and blurred vision, was referred to our clinic. …”
Get full text

Diagnostic Capability of Pattern Electroretinogram and Three Circumpapillary Retinal Nerve Fiber Layer Thickness Circle Diameter Scans in Glaucoma Suspects by Tirsi A, Tsai J, Abizadeh A, Kacaj D, Procyk O, Gliagias V, Leung N, Yang H, Park SC, Tello C

“…Andrew Tirsi,1,2 Joby Tsai,3 Aaron Abizadeh,2 Danielle Kacaj,4 Oksana Procyk,1 Vasiliki Gliagias,2 Nicholas Leung,2 Hanwen Yang,2 Sung Chul Park,1,2 Celso Tello1,2 1Department of Ophthalmology, Manhattan Eye, Ear, and Throat Hospital/Northwell Health, New York, NY, USA; 2Donald and Barbara Zucker School of Medicine at Hofstra/Northwell Health, Hempstead, NY, USA; 3Broward Health, Department of Ophthalmology, Fort Lauderdale, FL, USA; 4Cornell University, Ithaca, NY, USACorrespondence: Andrew Tirsi, Manhattan Eye Ear & Throat Hospital/Northwell Health, Department of Ophthalmology, 210 East 64th Street, New York, NY, 10065, USA, Tel +1 201 982 4168 ; +1 646 785 8217, Email atirsi@northwell.eduPurpose: To assess the diagnostic capability of pattern electroretinography (PERG) and varying circumpapillary optical coherence tomography (OCT) scan diameters in glaucoma suspects (GS).Methods: This is a prospective, cross-sectional study. Circumpapillary retinal nerve fiber layer thickness (RNFLT) was measured using spectral domain OCT in 49 eyes from 26 patients (36 normal, 13 GS) in three circle diameters (3.5, 4.1, and 4.7 mm). …”
Get full text

Correlation between Retinal Changes and Visual Function in Late-Stage Vogt-Koyanagi-Harada Disease: An Optical Coherence Tomography Study by Min Zhou, Chunhui Jiang, Ruiping Gu, Zhongcui Sun, Nancy Huynh, Qing Chang

“…The OCT revealed that the outer retina and retinal pigment epithelium (RPE) were mainly affected. …”
Get full text

Retrospective Comparison of 27-Gauge and 25-Gauge Microincision Vitrectomy Surgery with Silicone Oil for the Treatment of Primary Rhegmatogenous Retinal Detachment by Jie Li, Bo Zhao, Sanmei Liu, Fang Li, Wentao Dong, Jie Zhong

“…To retrospectively compare the safety and effectiveness of 27-gauge (27G) microincision vitrectomy surgery (MIVS) with 25-guage (25G) MIVS for the treatment of primary rhegmatogenous retinal detachment (RRD) with silicone oil tamponade. …”
Get full text

Characterization of Site-Specific Phosphorylation of NF-κB p65 in Retinal Cells in Response to High Glucose and Cytokine Polarization by Haoshen Shi, Elizabeth A. Berger

“…Phosphorylation of NF-κB p65 sites was examined in human primary retinal endothelial cells (HREC) and MIO-M1 Müller cells after exposure to high glucose (HG) and pro- or anti-inflammatory cytokines. …”
Get full text

Combination of Navigated Macular Laser Photocoagulation and Anti-VEGF Therapy: Precise Treatment for Macular Edema under Dry Retinal Conditions by Ernest V. Boiko, Dmitrii S. Maltsev

Get full text

Incidence and Characteristics of Patients with Visual Impairment due to Macular Edema Secondary to Retinal Vein Occlusion in a Representative Canadian Cohort by Robert J. Petrella, Julie Blouin, Brian Davies, Martin Barbeau

“…Retinal vein occlusion (RVO) is an obstruction of the retinal venous system, and macular edema (ME) is a complication of RVO that can lead to blindness. …”
Get full text

Evaluation of Retinal Pigment Epithelial Cell Cytotoxicity of Recombinant Tissue Plasminogen Activator Using Human-Induced Pluripotent Stem Cells by Hiroyuki Kamao, Atsushi Miki, Junichi Kiryu

“…The aim of this study is to validate the concept of cytotoxicity testing using hiPSC-derived retinal pigment epithelium (hiPSC-RPE) by comparing the responsiveness of human fetal RPE (hfRPE) and human RPE cell line (ARPE19) to recombinant tissue plasminogen activator (rtPA). …”
Get full text

Assessment of Ganglion Cell Complex and Peripapillary Retinal Nerve Fiber Layer Changes following Cataract Surgery in Patients with Pseudoexfoliation Glaucoma by Ahmed A. Abdelghany, Moataz A. Sallam, Abdallah A. Ellabban

“…To assess eye pressure, ganglion cell complex, and retinal nerve fiber layer changes following cataract surgery in patients with pseudoexfoliation glaucoma. …”
Get full text

Comparison of CRISPR-Cas13b RNA base editing approaches for USH2A-associated inherited retinal degeneration by Lewis E. Fry, Lauren Major, Ahmed Salman, Lucy A. McDermott, Jun Yang, Andrew J. King, Michelle E. McClements, Robert E. MacLaren

“…These results support the development of transcriptome targeting gene editing therapies for retinal disease.…”
Get full text

Trimethylamine-N-Oxide Promotes High-Glucose-Induced Dysfunction and NLRP3 Inflammasome Activation in Retinal Microvascular Endothelial Cells by Lidan Xue, Lili Huang, Yajing Tian, Xin Cao, Yu Song

“…However, the effect of TMAO on retinal cells under high-glucose conditions remains unclear. …”
Get full text

Incidence and Risk Factors of Iatrogenic Retinal Breaks: 20-Gauge versus 25-Gauge Vitrectomy for Idiopathic Macular Hole Repair by Norio Fujiwara, Goji Tomita, Fumihiko Yagi

“…We compared the incidences of iatrogenic retinal breaks and postoperative retinal detachment between eyes that underwent 20-gauge vitrectomy and those that underwent 25-gauge vitrectomy for idiopathic macular hole repair. …”
Get full text