The impact of margins and re‐resection in pediatric synovial sarcoma by Andres F. Espinoza, Priya B. Shetty, Jillian C. Jacobson, Hannah Todd, Kelley Harrell, Alfred F. Trappey, John Doski, Eumenia C. Castro, Nicole I. Montgomery, M. Fatih Okcu, Rajkumar Venkatramani, Dai H. Chung, Sanjeev A. Vasudevan

“…Second, our study extends this finding to report negative margins on initial resection or re‐resection is associated with better OS/EFS than positive margins on initial resection or re‐resection. …”
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Ground-based Characterization of (98943) Torifune 2001 CC21, the Target of the Hayabusa2# Space Mission by Marcel M. Popescu, Eri Tatsumi, Javier Licandro, Miguel R. Alarcon, Javier Rodríguez Rodríguez, Miquel Serra-Ricart, Julia de León, Joaquín Fernandez Martin, David Morate, Gabriel N. Simion, Bogdan Alexandru Dumitru, Daniel Nicolae Berteşteanu, George Pantelimon Prodan, Masatoshi Hirabayashi

“…The large number of light curves allows us to estimate its axis ratio, its convex shape, and its pole orientation, λ  = 301 ^∘  ± 35 ^∘ , $\beta =8{9}_{-6}^{+1^\circ }$ , and ϵ  = 5 ^∘  ± 3 ^∘ , respectively, which indicate a prograde rotation. We report the semiaxis of the equivalent ellipsoid, a = 0.42 ${}_{0.06}^{+0.08}$ km, b = 0.16 ${}_{0.04}^{+0.05}$ km, and c = 0.17  ±  0.03 km. …”
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Phantom motor execution as a treatment for phantom limb pain: protocol of an international, double-blind, randomised controlled clinical trial by Brian E McGuire, Lina Bunketorp-Käll, Eva Lendaro, Liselotte Hermansson, Helena Burger, Corry K Van der Sluis, Monika Pilch, Katarzyna Kulbacka-Ortiz, Ingrid Rignér, Anita Stockselius, Lena Gudmundson, Cathrine Widehammar, Wendy Hill, Sybille Geers, Max Ortiz-Catalan

“…The results will be published according to the Consolidated Standards of Reporting Trials guidelines in a peer-reviewed journal.Trial registration number NCT03112928; Pre-results.…”
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Impact of the COVID-19 Event on Trip Intensity and Air Quality in Southern China by Shun Wan, Kangping Cui, Ya-Fen Wang, Jhong-Lin Wu, Wei-Syun Huang, Kaijie Xu, Jiajia Zhang

“…Abstract The COVID-19 epidemic discovered and reported at the end of December 2019 and began spreading rapidly around the world. …”
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Sangre Por Salud (SPS) Biobank: cohort profile by Richard R Sharp, Euijung Ryu, Janet E Olson, Karen Meagher, James R Cerhan, Davinder Singh, Suzette Bielinski, Emmil Zarrugh, Marlene E Girardo, Giovanna Moreno Garzon, Valentina Hernandez, Sharon Levey, Crystal Gonzalez, Daniela B Pompa, Gabriel Q Shaibi, Lawrence Mandarino, Steven Thibodeau, Elena De Filippis

“…At time of recruitment, hypertension, hyperlipidaemia and depression affected 22%, 20% and 13% of the cohort, respectively.Future plans We plan to regularly update the participants’ electronic health records and self-reported health data to longitudinal research. Additionally, we plan to obtain a more comprehensive genomic analysis on the entire cohort, ensuring greater research interest and investigation into the underlying genetic factors that contribute to disease susceptibility in this cohort.…”
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Physician characteristics associated with the referral from general practitioners to dental surgeons and proposal for a referral letter template endorsed by dental surgeons in Fran... by Matthias Lamauviniere, Jan Chrusciel, Cassandre Finot, Adrien Basset, Maximillien Graftieaux, Aline Ohl-Hurtaud, Stéphane Sanchez

“…Medical correspondence between GPs and dental surgeons was reported to be insufficient by most dental surgeons (91.4%). …”
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Single-chain variable fragment affinity tuning can optimize anti-AML CAR-NK cell functionality by Marianna Zahurak, Ravi Varadhan, Ilias Christodoulou, Ruyan Rahnama, Jun Choe, Huilin Yang, Monika Kizerwetter, Christian Guaraca, Natalie Jordan Holl, Stamatia C Vorri, Megan Zinsky, Danielle G Jones, Nikol Garcia Espinoza, Yun-Huai Kuo, Jamie B. Spangler, Challice L. Bonifant

“…Here, we study the functional consequences of CAR binding affinity and targeted epitope on CAR-NK cell activation, cytolytic synapse formation, and antitumor activity.Methods We characterized NK-92 and primary NK cell populations expressing variant affinity AML-specific CARs containing single-chain variable fragments (scFvs, 26292 or 7G3) targeting two epitopes on CD123. 26292 affinity variants were discovered through directed evolution of an error-prone mutagenic library, while 7G3 affinity variants were previously reported. The resulting CAR-NK cell panel was studied with in vitro binding, activation, and cytotoxicity studies and in mouse xenograft models.Results 26292 and 7G3 CARs of variable CD123 binding affinities were highly expressed in NK cells and conferred antigen-specific activation in vitro. …”
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Transcatheter edge-to-edge mitral valve repair <i>versus</i> medical therapy for secondary mitral regurgitation: a meta-analysis of randomized controlled trials by Emídio Mata, Bárbara Lage Garcia, Mariana Tinoco, Margarida Castro, Luísa Pinheiro, João Português, Francisco Ferreira, Silvia Ribeiro, Bruno Melica, António Lourenço

“…A study-level random-effects meta-analysis was conducted using trial-reported point estimates. Seven records from three trials (COAPT, MITRA-FR, RESHAPE-HF2) involving 1426 participants were included. …”
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Uncovering the Hidden Physical Structures and Protostellar Activities in the Low-metallicity S284-RE Region: Results from ALMA and JWST by O. R. Jadhav, L. K. Dewangan, Aayushi Verma, N. K. Bhadari, A. K. Maity, Saurabh Sharma, Mamta

“…The Spitzer ratio 4.5 μ m/3.6 μ m map traces the H _2 outflows in this filament, where previously reported young stellar objects (YSOs) are spatially distributed. …”
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Endothelial Activation and Stress Index (EASIX) to predict mortality after allogeneic stem cell transplantation: a prospective study by Axel Benner, Peter Dreger, Grzegorz W Basak, Christian Koenecke, Olaf Penack, Christophe Peczynski, Lucia López Corral, Ivan Moiseev, Hélène Schoemans, Zinaida Peric, Thomas Luft, Simona Sica, Mutlu Arat, Maija Itäla-Remes, Nicolaas P M Schaap, Michal Karas, Ludek Raida, Thomas Schroeder, Elisabetta Metafuni, Tulay Ozcelik, Brenda M Sandmaier, Lambros Kordelas

“…Background We previously reported that the “Endothelial Activation and Stress Index” (EASIX; ((creatinine×lactate dehydrogenase)÷thrombocytes)) measured before start of conditioning predicts mortality after allogeneic hematopoietic stem cell transplantation (alloSCT) when used as continuous score. …”
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Estimating the association between cigarette and e-cigarette use patterns and SARS-CoV-2 negative conversion time: retrospective online survey in China by Ying Xie, Yinghua Li, Zheng Su, Xueyan Han, Zhao Liu, Zhenxiao Huang, Anqi Cheng, Xinmei Zhou, Jinxuan Li, Rui Qin, Xiaowen Wei, Yi Liu, Xin Xia, Qingqing Song, Liang Zhao, Kian Fan Chung, Dan Xiao, Chen Wang

“…Abstract Background Cigarette smoking has been reported to be associated with SARS-CoV-2 negative conversion, while little is known about the effect of its dual use with e-cigarettes. …”
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Antimicrobial susceptibilities of oral Neisseria from men on HIV pre-exposure prophylaxis in Hanoi, Vietnam by Huan Vinh Dong, Paul Adamson, Dieu Hoa Pham, Quynh Hoa Pham, Hai Ha Long Le, Loc Quang Pham, Hao Thi Minh Bui, Giang Minh Le, Jeffrey D. Klausner

“…Results: There were 42 male participants, the median age was 26 years and 29% (n = 12) reported using antibiotics in the past 6 months. In total, 48 Neisseria isolates were recovered; N. sicca/subflava was the most common species (50%; n = 24), followed by N. mucosa (38%; n = 18). …”
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Chemical Composition Characteristics and Source Apportionment of PM2.5 in Ceramic Industrial Base during Winter by Xiang Tu, Xiaozhen Fang, Hansun Fang, Changlin Ye, Zugen Liu, Xuehui Jia, Dan He, Jinliang Wang, Hong Huang, Changwei Zou, Chenglong Yu

“…Abstract The national architectural ceramic industrial center in east China is suffering from serious ambient fine particle pollution. The study reported herein describes an effort to ascertain the degree and sources of the PM2.5 collected in a ceramic industrial base during winter. …”
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Smoking as a risk factor for lung cancer in women and men: a systematic review and meta-analysis by Sanne A E Peters, Mark Woodward, Paul Mitchell, Rachel R Huxley, Gemma Taylor, Linda M O’Keeffe

“…Individual participant data from three sources were also available to supplement analyses of published literature.Eligibility criteria for selecting studies Cohort studies reporting the sex-specific relative risk (RR) of lung cancer associated with smoking.Results Data from 29 studies representing 99 cohort studies, 7 million individuals and &gt;50 000 incident lung cancer cases were included. …”
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Performance of artificial intelligence on cervical vertebral maturation assessment: a systematic review and meta-analysis by Termeh Sarrafan Sadeghi, Seyed AmirHossein Ourang, Fatemeh Sohrabniya, Soroush Sadr, Parnian Shobeiri, Saeed Reza Motamedian

“…In the present review, we included studies that reported AI models’ performance on CVM assessment. …”
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Assessment of Microbiological Indoor Air Quality in Cattle Breeding Farms by Justyna Szulc, Małgorzata Okrasa, Katarzyna Dybka-Stępień, Michael Sulyok, Adriana Nowak, Anna Otlewska, Bogumiła Szponar, Katarzyna Majchrzycka

“…High-throughput sequencing revealed extensive biodiversity in the microorganisms, which hitherto has not been reported for cattle farms. Of the identified species, those belonging to the genera Bacteroides, Corynebacterium, Staphylococcus, Ruminococcus, Aspergillus and Cladosporium potentially affect human and cattle health. …”
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Out-of-field dose assessment for pencil beam scanning proton radiotherapy versus photon radiotherapy for breast cancer in pregnant women by Menke Weessies, Murillo Bellezzo, Britt J.P. Hupkens, Frank Verhaegen, Gloria Vilches-Freixas

“…PBS-PRT measurements showed that the total equivalent dose was below the 100 mSv threshold outlined in AAPM Task Group Report No. 36 for a 30-week pregnancy, even under a worst-case scenario, maintaining treatment goals. …”
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Chemical Characterization of Marine Aerosols in a South Mediterranean Coastal Area Located in Bou Ismaïl, Algeria by Sidali Khedidji, Konrad Müller, Lyes Rabhi, Gerald Spindler, Khanneh Wadinga Fomba, Dominik van Pinxteren, Noureddine Yassaa, Hartmut Herrmann

“…Overall, the concentrationrace metals, carbonaceous aerosols, the anhydrosugars levoglucosan and arabitol, dicarboxylic acids, and semi-volatile organic coms of selected ionic species were similar to those reported at other Mediterranean sites, ranging from 3.62 µg m−3 to 5.20 µg m−3 for the monthly total WSI. …”
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A stratified two-stage tumor molecular profiling algorithm to identify clinically actionable molecular alterations in pancreatic cancer☆ by S. Hussung, D. Akhoundova, C. Pistoni, D. Lenggenhager, A. Töpfer, C. Pauli, B. Pestalozzi, C. Britschgi, M. Zoche, M. Rechsteiner, H. Moch, A. Weber, R. Fritsch

“…Based on pre-specified events (KRAS wild type, mismatch repair deficiency, molecular tumor board recommendation), subsequent comprehensive molecular testing was carried out (stage 2). We report molecular findings and patient outcomes. Results: A total of 94 PC patients were included in the study. …”
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Prevalence of symptoms suggestive of sleep apnea among children and its impact on academic performance by Silvia D. Boyajian, Muna A. Salameh, Kholoud Alzyoud, Enas A. Amaireh, Lujayn Badah, Malek Al Qutami, Mira Alsharayri, Osama Abubaker, Rzan Shwashreh

“…The prevalence of OSA (defined as SRBD score > 33%) was reported as a proportion along with its 95% confidence interval. …”
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