A Retrospective Patient Chart Review and Survey in Patients with Cryopyrin-associated Periodic Syndromes Treated with Anakinra by Helen J. Lachmann, Renée J.G. Arnold, Marco Gattorno, Isabelle Koné-Paut, Alberto Ferreira, Jasmin Kümmerle-Deschner

“…During the past 12 months on anakinra, four of five (80%) patients who recalled experiencing flares reported cancelling social activities and staying home as the most common courses of action. …”
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Chromatin remodeling (SWI/SNF) complexes, cancer, and response to immunotherapy by Razelle Kurzrock, Shumei Kato, Nithya Krishnamurthy, Scott Lippman

“…Remarkable, although anecdotal, responses to ICB have been reported in both SMARCA4-aberrant and SMARCB1-aberrant advanced cancers. …”
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Diagnostic pathways for breast cancer in 10 International Cancer Benchmarking Partnership (ICBP) jurisdictions: an international comparative cohort study based on questionnaire and... by David Weller, Usha Menon, Alina Zalounina Falborg, Henry Jensen, Andriana Barisic, Anne Kari Knudsen, David H Brewster, Victoria Cairnduff, Eva Grunfeld, Elizabeth Harland, Mats Lambe, Rebecca-Jane Law, Yulan Lin, Martin Malmberg, Donna Turner, Richard D Neal, Victoria White, Samantha Harrison, Peter Vedsted, Una MacLeod, Conan Donnelly, Anna Gavin, Jon Emery, Oliver Bucher, Jatinderpal Kalsi, Chantelle Anandan, Evangelia Ourania Fourkala, Therese Kearney, Marie-Louise Essink-Bot, Sigrun Saur Almberg, Breann Hawryluk, Jacqueline Kelly, Jackie Boylan, Jan Willem Coebergh, David Brewster, Stefan Bergström, Victoria Hammersley, Rebecca Bergin, Alina Zalounina Falborg, Andriana Barisi, Kerry Moore, Maria Rejmyr Davis

“…PCPs reported 77% presented with symptoms, of whom 81% were urgently referred with suspicion of cancer (ranging from 62% to 92%; Norway and Victoria). …”
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Pattern of Orbito-ocular Tumours in Nigeria: a systematic review by Godswill I. Nathaniel, Ugochukwu A. Eze, Arinze A. Onwuegbuna, Chigozie I. Echieh, Helen A. Alen

“…Result A total of two thousand six hundred and forty-three (2643) patients with orbito-ocular tumors was reported to have been published in Nigerian articles over the past five decades, the age range of the reported cases was 1 month—93 years with a male preponderance. …”
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Recruitment and retention of participants in randomised controlled trials: a review of trials funded and published by the United Kingdom Health Technology Assessment Programme by Stephen J Walters, Daniel Hind, Richard M Jacques, Steven A Julious, Joanne Rothwell, Oscar Bortolami, Laura Flight, Inês Bonacho dos Anjos Henriques-Cadby, Christopher Knox, Ben Nadin, Michael Surtees

“…Many trials fail to reach their planned sample size within the envisaged trial timescale and trial funding envelope.Objectives To review the consent, recruitment and retention rates for single and multicentre randomised control trials funded and published by the UK's National Institute for Health Research (NIHR) Health Technology Assessment (HTA) Programme.Data sources and study selection HTA reports of individually randomised single or multicentre RCTs published from the start of 2004 to the end of April 2016 were reviewed.Data extraction Information was extracted, relating to the trial characteristics, sample size, recruitment and retention by two independent reviewers.Main outcome measures Target sample size and whether it was achieved; recruitment rates (number of participants recruited per centre per month) and retention rates (randomised participants retained and assessed with valid primary outcome data).Results This review identified 151 individually RCTs from 787 NIHR HTA reports. …”
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Validation methods for encapsulated faecal microbiota transplantation: a scoping review by Nina Rågård, Simon Mark Dahl Baumwall, Sara Ellegaard Paaske, Mette Mejlby Hansen, Katrine Lundby Høyer, Susan Mikkelsen, Christian Erikstrup, Jens Frederik Dahlerup, Christian Lodberg Hvas

“…Future studies should report validation covariables to enable accurate comparative assessments of clinical effects.…”
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The responsiveness of surgical research to Māori in Aotearoa, New Zealand—a scoping reviewResearch in context by Jamie-Lee Rahiri, Noah Appleby, Makayla Kahi, Annaliese Wheeler, Jason Tuhoe, Shanthi Ameratunga, Rachelle Love, Wiremu MacFater, Matire Harwood

“…More than half of all studies (55%) did not report Māori leadership, governance, and co-authorship. …”
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An exploratory study of the tax rate reconciliation disclosures of JSE listed companies by Rudie Nel, Anja van Niekerk

“…Results: The main reconciling item category identified over the reporting periods was permanent differences that could be indicative of aggressive tax planning and warrant further research. …”
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Robotic Assistance in Simultaneous Bilateral Medial Unicompartmental Knee Arthroplasty: A Retrospective Cohort Study of 126 Knees Demonstrating Enhanced Radiographic Accuracy and C... by Valentina Rossi, MD, Constant Foissey, MD, Andreas Fontalis, MD, MSc, MRCS, Gabriel Gaggiotti, MD, Stefano Gaggiotti, MD, Elvire Servien, MD, PhD, Sébastien Lustig, MD, PhD

“…Data on surgical outcomes, patient-reported outcome measures (International Knee Society score), and radiographic measurements were collected. …”
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Maternal knowledge, attitude and practice regarding commercial oral rehydration salt solution: experience from a diarrhoeal disease hospital in Bangladesh by Tahmeed Ahmed, Mohammod Jobayer Chisti, Md Fuad Al Fidah, Sharika Nuzhat, Md Ridwan Islam, Shoeb Bin Islam, Md Mushfiqur Rahman, Sneha Paul, Mahfuz-Un Nesa, Devjani Chowdhury, Shayontan Fardin Nabi, Awni Mokhtar Sallam Ali Awn, Liaquat Ali Khan, Chowdhury Ali Kawser

“…The majority (97.4%) reported being aware of the process of ORS preparation. …”
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Otodectes cynotis (Acari: Psoroptidae) infestations in Southern pudus (Pudu puda): In situ and ex situ data of an unexpected host-parasite record by Caroline Wilhelm, Edwin Kniha, Pamela Muñoz, Ángelo Espinoza, Laura Platner, Saskia Dreyer, Lisa Grund, Zoë Tess Lara Lindhorst, Ulrich Gärtner, Julia Walochnik, Anja Taubert, Dominik Fischer, Stephan Hering-Hagenbeck, Carlos Hermosilla, David Ebmer

“…In the current study, we report O. cynotis infestations in Southern pudus (Pudu puda), categorized in the IUCN red list as near threatened. …”
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The COVID-19 pandemic and blood utilisation in South Africa by R Swanevelder, P-L Wessels, V J Louw, A Swarts, M Lennards, K van den Berg

“…The COVID‐19 pandemic, first reported in December 2019, affected every sector of every country worldwide. …”
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Parents’ use of coercive and indulgent feeding practices for children with avid eating behaviour: an Ecological Momentary Assessment study by Abigail Pickard, Katie L. Edwards, Claire Farrow, Emma Haycraft, Moritz Herle, Clare Llewellyn, Helen Croker, Alice Kininmonth, Jacqueline Blissett

“…Over 10 days, participants completed EMA surveys via a mobile app to report on their mood, stress, feeding goals, and feeding practices during eating occasions. …”
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Genomic characterization of antimicrobial-resistance and virulence factors in Salmonella isolates obtained from pig farms in Antioquia, Colombia. by María Isabel García-Álvarez, Juana L Vidal, Pilar Donado-Godoy, Jared Smith, Nikki Shariat, María Fernanda Valencia, Luis M Gómez-Osorio, Sara López-Osorio, Jenny J Chaparro-Gutiérrez

“…<h4>Background</h4>Occurrence of antimicrobial-resistant Salmonella strains has been reported worldwide, because of inappropriate use of antimicrobial products in either humans or animals. …”
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Purpose built catheters for minimally invasive surfactant therapy: Experience from a Canadian tertiary level neonatal intensive care unit by Talib Al Harthy, Michael R Miller, Orlando daSilva, Soume Bhattacharya

“… # Conclusion This is the first study in Canada to report MIST with purpose-built catheters. Overall, the success rate was equally high with both catheters. …”
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Prevalence of signs and symptoms of temporomandibular disorders (TMD) in a sample of medical students in Erbil city by Dilan Burhan Yousif, Zana Qadir Omer

“…The most common symptom reported by students were joint sounds and joint fatigue. …”
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Psychometric validation of the Danish BREAST-Q reconstruction module by Cecilie Balslev Willert, Karl Bang Christensen, Pernille Envold Bidstrup, Lene Mellemkjær, Anne-Marie Axø Gerdes, Lisbet Rosenkrantz Hölmich

“…Aim/background: Patient-reported outcome measurement instruments are important tools in understanding a breast reconstruction's impact on the patients' quality of life. …”
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Biology of selective caries removal: a systematic scoping review protocol by Helge Knüttel, Matthias Widbiller, Rita Weiler, Kerstin M Galler, Wolfgang Buchalla, Konstantin J Scholz

“…It presents a lower risk of accidental pulp exposure, which reportedly has a positive effect on tooth survival. …”
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TARGET Protein: the effect of augmented administration of enteral protein to critically ill adults on clinical outcomes—statistical analysis plan for a cluster randomized, cross-se... by Sophie Zaloumis, Matthew J. Summers, Jeffrey J. Presneill, Rinaldo Bellomo, Lee-anne S. Chapple, Marianne J. Chapman, Adam M. Deane, Suzie Ferrie, Craig French, Sally Hurford, Nima Kakho, Matthew J. Maiden, Stephanie N. O’Connor, Sandra L. Peake, Emma J. Ridley, An Tran-Duy, Patricia J. Williams, Paul J. Young, Amalia Karahalios, on behalf of the TARGET Protein Investigators, the Australian, New Zealand Intensive Care Society Clinical Trials Group

“…Conclusion This statistical analysis plan enables transparent reporting of the TARGET Protein trial. It will reduce the risk of potential selective reporting biases. …”
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Anterior clinoid process metastasis with sudden loss of vision: role of emergency optic nerve decompression by Marta Rico-Pereira, Fernando Muñoz-Hernández

“…Conclusions Metastasis to the anterior clinoid process is very uncommon, with only one case previously reported in the literature. In cases of visual impairment, symptoms may deteriorate rapidly to complete loss of vision, so urgent decompressive surgery of the optic nerve may be indicated to recover visual function, although recovery may be partial.…”
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