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241
Novel adaptive immune systems in pristine Antarctic soils
Published 2025-01-01“…Although several studies have investigated the phylogenetic repertoire of bacteria and viruses in these poly-extreme environments with freezing temperatures, high ultra violet irradiation levels, low moisture availability and hyper-oligotrophy, the evolutionary mechanisms governing microbial immunity remain poorly understood. …”
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242
Discrimination between the facial gestures of vocalising and non-vocalising lemurs and small apes using deep learning
Published 2025-03-01“…Our approach facilitates the investigation of facial repertoire across primate species and behavioural contexts, enabling comparative research in primate communication.…”
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243
Rotationsprinzip und synthetische Reprisenfunktion im Klavierkonzert des späten 18. und frühen 19. Jahrhunderts
Published 2021-06-01“…Instead of a “rapprochement with sonata form,” the generic identity of the concerto in this repertoire is strengthened by an array of different formal procedures alien to the concertos of Mozart.…”
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244
Maternal singing and speech have beneficial effects on preterm infant’s general movements at term equivalent age and at 3 months: an RCT
Published 2025-01-01“…BackgroundGeneral Movements (GMs) are part of the spontaneous movement repertoire and assessing them helps to determine the integrity of the central nervous system in newborns. …”
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245
Reverse transcriptase inhibitors diminish systemic proinflammatory responses to bacterial pathogens
Published 2025-02-01“…In the liver, NRTI administration following E. coli inoculation reduced the expression of a large repertoire of proinflammatory transcripts. NRTIs also had systemic anti-inflammatory effects, including reducing proinflammatory cytokine levels in serum in response to E. coli in different mouse strains. …”
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246
Concurrent Panniculectomy With Abdominal Wall Reconstruction: A Propensity-scored Matched Study of Quality Improvement Outcomes
Published 2024-12-01“…This large dataset demonstrates the safety of a single-stage repair that should be part of hernia surgeons' repertoire.…”
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247
Structure- and machine learning-guided engineering demonstrate that a non-canonical disulfide in an anti-PD-1 rabbit antibody does not impede antibody developability
Published 2024-12-01“…Rabbits produce robust antibody responses and have unique features in their antibody repertoire that make them an attractive alternative to rodents for in vivo discovery. …”
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248
Identification of novel fructo-oligosaccharide bacterial consumers by pulse metatranscriptomics in a human stool sample
Published 2025-01-01“…Our approach can be applied to identify consumers of understudied glycans and expand our prebiotic repertoire. It can also be used to study prebiotic glycans directly in stool samples in distinct patient populations to help delineate the prebiotic mechanism.…”
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249
Pre-transplant T-cell clonal analysis identifies CD8+ donor reactive clones that contribute to kidney transplant rejection
Published 2025-02-01“…DRTC were then tracked in post-transplant biopsies, blood, and urine samples in a cohort of kidney transplant recipients.ResultsIn patients with an abnormal biopsy, the majority of CD8+ DRTC found within the allograft were detected in the circulating pre-transplant repertoire. Circulating CD8+ DRTC were more abundant pre- and post-transplant in patients that received non-lymphodepletional induction and developed an abnormal biopsy when compared to stable patients. …”
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250
Préférence manuelle chez les gibbons
Published 2016-01-01“…Un des problèmes est le manque de données chez certaines espèces-clés comme notamment au sein des hylobatidés, alors que ce taxon est particulièrement intéressant dans ce contexte : 1. ils sont très proches de l’homme et partagent un répertoire vocal complexe, ils pourraient donc partager certaines voies neurologiques pour leur vocalisation complexe ; 2. leur adaptation à l’arboricolie s’associe à des contraintes posturales uniques ; 3. il y a peu de données sur leur latéralité, et celles-ci sont contradictoires. …”
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251
Acute Exposure to Microcystin-Producing Cyanobacterium Microcystis aeruginosa Alters Adult Zebrafish (Danio rerio) Swimming Performance Parameters
Published 2011-01-01“…When an organism is exposed to environmental perturbations, alterations in normal behavioral patterns occur. Behavioral repertoire represents the consequence of a diversity of physiological and biochemical alterations. …”
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252
New approach to generating of human monoclonal antibodies specific to the proteolytic domain of botulinum neurotoxin A
Published 2024-07-01“…The affinity-matured human antibody repertoire may be ideal as a source for antibody therapeutics against BoNTs. …”
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253
Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity
Published 2025-01-01“…Interestingly, we also observed upregulation of proteins involved in MHC-I presentation, suggesting that defective β-cell autophagy may alter the immunopeptidome, or antigen repertoire, and enhance β-cell immune visibility. In support of this hypothesis, we observed increased MHC-I expression and CD45+ immune cells in ATG7Δβ-cell islets. …”
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254
Omics-Based Comparison of Fungal Virulence Genes, Biosynthetic Gene Clusters, and Small Molecules in <i>Penicillium expansum</i> and <i>Penicillium chrysogenum</i>
Published 2024-12-01“…Our findings provide a solid omics-based foundation of small molecule production in these two fungal species with implications in postharvest context and expand the current knowledge of the <i>Penicillium</i>-derived chemical repertoire for broader fundamental and practical applications.…”
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255
Notation publications in the context of musical life in Lithuania in the XVI-XVII centuries
Published 2024-08-01“…They revealed the formation of a local hymn repertoire and the variability and great flexibility of the hymn melodies, some hymns having only empty staves provided. …”
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256
PEPITEM, its tripeptide pharmacophores and their peptidomimetic analogues regulate the inflammatory response through parenteral and topical dosing in models of peritonitis and psor...
Published 2025-03-01“…This expanded functional repertoire of PEPITEM and its derivatives provides innovative tools for countering immune and stromal cell-induced pathology in IMIDs. …”
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257
Imagined Libya: geopolitics of the margins
Published 2022-12-01“…After more than a century of substantial disregard, the rise of a pan-Ottoman geopolitical repertoire in Turkey and the nationalistic emphasis on the redeeming of the vatan (homeland) provide the key for interpreting Turkey’s resurrecting interest in Libya, and the justification of its military intervention vis-à-vis Ankara’s domestic audiences. …”
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258
Limnospira (Cyanobacteria) chemical fingerprint reveals local molecular adaptation
Published 2025-02-01“…The impact of accessory gene repertoires on respective chemical adaptations was also determined. …”
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259
Liver metastases of colorectal cancer contain different subsets of tissue-resident memory CD8 T cells correlated with a distinct risk of relapse following surgery
Published 2025-12-01“…Supporting this observation, CD103+CD69+ TRM cells showed a more oligoclonal TCR repertoire. Both TRM subsets presented higher cytotoxic and functional capacity compared to non-TRM cells. …”
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260
Immunoregulatory programs in anti‐N‐methyl‐D‐aspartate receptor encephalitis identified by single‐cell multi‐omics analysis
Published 2025-01-01“…In parallel, single‐cell B cell receptor sequencing (scBCR‐seq) and repertoire analysis were conducted to assess antigen‐driven clonal expansion within the B cell population. …”
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