Glucose‐induced LINC01419 reprograms the glycolytic pathway by recruiting YBX1 to enhance PDK1 mRNA stability in hepatocellular carcinoma by Yanfang Liu, Junjiao Song, Qili Shi, Bing Chen, Wenying Qiu, Yizhe Liu, Shenglin Huang, Xianghuo He

Get full text

Erratum to “miR-223 Inhibits the Polarization and Recruitment of Macrophages via NLRP3/IL-1β Pathway to Meliorate Neuropathic Pain” by Junsong Zhu, Jinmei Yang, Jianguo Xu

Get full text

Tail coiling behaviour around conspecific’s body during fur rubbing in white-faced capuchins by Helene Meunier, Jean-Louis Deneubourg, Odile Petit

Subjects: Get full text

A holistic and sustainable approach to public health staffing and workforce development by Paulani Mui, Ruth Maiorana, Beth Resnick

Subjects: Get full text

CircHIPK2 recruits SRSF1 to increase TXNIP mRNA stability and promotes autophagy-dependent ferroptosis and apoptosis in myocardial ischemia-reperfusion injury by Zhu Zhang, Jinqi Hao, Qinghong Qiao, Junting Song, Yanqin Yu

“…Additionally circHIPK2 recruited SRSF1 to target TXNIP and stabilized TXNIP mRNA expression. …”
Get full text

YTHDF2 in peritumoral hepatocytes mediates chemotherapy-induced antitumor immune responses through CX3CL1-mediated CD8+ T cell recruitment by Zhenyun Yang, Xin Wang, Yizhen Fu, Weijie Wu, Zili Hu, Qingyang Lin, Wei Peng, Yangxun Pan, Juncheng Wang, Jinbin Chen, Dandan Hu, Zhongguo Zhou, Li Xu, Yaojun Zhang, Jiajie Hou, Minshan Chen

“…Studies using tumor-bearing liver-specific Ythdf2 knockout mice revealed that hepatocyte YTHDF2 suppresses liver tumor growth through CD8+ T cell recruitment and activation. Additionally, YTHDF2 mediated the response to immunotherapy. …”
Get full text

HISTORICISING PARTY INTERNAL DEMOCRACY AND THE CHALLENGE OF DEMOCRATIC CONSOLIDATION IN NIGERIA’S FOURTH REPUBLIC, 1999-2023 by ADESOTE SAMSON ADESOLA, AKANDE SUNDAY ADEKUNLE

Subjects: Get full text

The staffing problem in the police during 1943–1944 and ways to resolve it by V. A. Grechenko

Subjects: Get full text

Spatial autocorrelation and host anemone species drive variation in local components of fitness in a wild clownfish population by Marrot, Pascal, Fauvelot, Cécile, Berumen, Michael L, Srinivasan, Maya, Jones, Geoffrey P, Planes, Serge, Pujol, Benoit

Subjects: “…clownfish, lifetime reproductive success, self-recruitment, spatial autocorrelation, PCNM…”
Get full text

Modern approaches and methods of formation and development of management personnel in a modern IT company by E. V. Yakovleva, R. G. Poldvey

Subjects: Get full text

General Volmar Anton von Shlippenbah – a Descendant of Livonian Knights by A. V. Bespalov, N. A. Kopylov

Subjects: Get full text

Les retours d’une exploration méthodologique croisant données Twitter, recrutement via Facebook et questionnaires web by Emmanuel Ravalet, Jean-François Lucas, Antoine Lohou

Subjects: Get full text

Biomimetic fabricated tubular graft in situ immobilized with peptides to restore the vascular structure and regulate the inflammation homeostasis through gastrodin coating by Shiwei Niu, Fan Li, Zhi Lin, Bo Chen, Lechun Lyu, Yongliang Jiang, Wanting Li, Jianlin Jiao, Yi Han, Di Lu, Lin Sun

Subjects: Get full text

A Digital-based Talent Acquisition Framework for Start-ups: A Qualitative Multiple Case Study by Mohammad Hosein Kenarroodi, Hasan Boudlaie

Subjects: Get full text

Planning for success but facing uncertainty: lessons learned from a native oyster, Ostrea lurida, restoration project in the Salish Sea by James T. McArdle, Julie S. Barber, Sarah K. Grossman, Lindy L. Hunter

Subjects: Get full text

Targeting sphingosine 1-phosphate receptor 3 inhibits T-cell exhaustion and regulates recruitment of proinflammatory macrophages to improve antitumor efficacy of CAR-T cells against solid tumor by Weiting Liao, Ge Gao, Xia He, Pei Shu, Qizhi Ma, Benxia Zhang, Diyuan Qin, Yongsheng Wang

“…Targeting S1PR3 was shown to remodel the TME through the recruitment of proinflammatory macrophages by promoting macrophage activation and proinflammatory phenotype polarization, resulting in improved CAR-T cell infiltration and amplified recruitment of CD8+T cells.Conclusions This work demonstrated targeting S1PR3 could increase the antitumor activities of CAR-T cell therapy at least partially by inhibiting T-cell exhaustion and remodeling the TME through the recruitment of proinflammatory macrophages. …”
Get full text

Correction: YTHDF2 in peritumoral hepatocytes mediates chemotherapy-induced antitumor immune responses through CX3CL1-mediated CD8+ T cell recruitment by Zhenyun Yang, Xin Wang, Yizhen Fu, Weijie Wu, Zili Hu, Qingyang Lin, Wei Peng, Yangxun Pan, Juncheng Wang, Jinbin Chen, Dandan Hu, Zhongguo Zhou, Li Xu, Yaojun Zhang, Jiajie Hou, Minshan Chen

Get full text

VANGL2 alleviates inflammatory bowel disease by recruiting the ubiquitin ligase MARCH8 to limit NLRP3 inflammasome activation through OPTN-mediated selective autophagy. by Huaji Jiang, Yingchao Xie, Zhiqiang Hu, Jiansen Lu, Jiahuan Zhang, Hongyu Li, Ke Zeng, Wenqiang Peng, Cheng Yang, Junsheng Huang, Zelong Han, Xiaochun Bai, Xiao Yu

“…Mechanistically, VANGL2 interacts with NLRP3 and promotes the autophagic degradation of NLRP3 through enhancing the K27-linked polyubiquitination at lysine 823 of NLRP3 by recruiting E3 ligase MARCH8, leading to optineurin (OPTN)-mediated selective autophagy. …”
Get full text

Using technology to increase reach and optimize consent experience for a large-scale research program by Emma Coen, Daniel P. Judge, Samantha Norman, John T. Clark, Andrew Cates, Randolph Thornhill, Kelly Hunt, Lori McMahon, Leslie Lenert, Caitlin G. Allen

Subjects: Get full text

The Equator Project Research School and Mentoring Network: Evaluated Interventions to Improve Equity in Geoscience Research by Natasha Dowey, Anya Lawrence, Munira Raji, Christopher Jackson, Rebecca Williams, Ben Fernando, Sam Giles, Jenni Barclay, Louisa Brotherson, Ethny Childs, Jacqueline Houghton, Anjana Khatwa, Keely Mills, George Jameson, Francisca Rockey, Steven Rogers, Catherine Souch

Subjects: Get full text