Molecular mechanisms induced by phase modifiers used in hydrometallurgy: consequences on transfer efficiency and process safety by El Maangar, Asmae, Prévost, Sylvain, Dourdain, Sandrine, Zemb, Thomas

“…However, an optimized process on an industrial scale has not yet been established. One of the main reasons is the lack of fundamental knowledge. Therefore, designing a cost-effective and adaptive formulation is still beyond the scope of possibilities. …”
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Advancing treatment choices: CDK4/6 inhibitor switching in HR+/HER2- metastatic breast cancer by Paola Zagami, Angela Esposito, Beatrice Taurelli Salimbeni, Pier Paolo Maria Berton Giachetti, Roberta Scafetta, Matteo Lambertini, Massimo Di Maio, Giuseppe Curigliano, Carmen Criscitiello, Saverio Cinieri

“…Yet, 49 % of respondents emphasized the need for more real world evidence on CDK4/6i switch safety and efficacy. 96 % of respondents reported discontinuation rates between 0% and 25 % of patients, with constipation and hematological toxicity being the most frequent treatment discontinuation reasons. The oncologists prescribing CDK4/6i switch reported that most of these patients were in first line treatment (85 %) and the most common second CDK4/6i most frequently initiated was palbociclib (69 %), then abemaciclib (17 %) and ribociclib (14 %). …”
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Five-year Variations in Air Pollutant Emissions with Ultra-low Emission Retrofits in a 660 MW Coal-fired Power Unit by Zhiyong Li, Zhuangzhuang Ren, Chengjing Cao, Chen Liu, Zhen Zhai, Jixiang Liu, Ziyi Zhan, Changtao Huang, Lan Chen, Hongdan Yuan

“…Unlike EFs expressed in mg m−3, the most decreases of EFs in kg h−1 and g MWh−1 in 2015 by more than 97.0% compared to 2014 for three air pollutants arisen from reasonable air supply or enhancement in thoroughness of coal combustion.…”
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Understanding the Broad-line Region of Active Galactic Nuclei with Photoionization. I. The Moderate-accretion Regime by Qiaoya Wu, Yue Shen, Hengxiao Guo, Scott F. Anderson, W. N. Brandt, Catherine J. Grier, Patrick B. Hall, Luis C. Ho, Yasaman Homayouni, Keith Horne, Jennifer I-Hsiu Li, Donald P. Schneider

“…The UV/optical line strengths and their dependences on accretion parameters are reasonably well reproduced by the locally optimally emitting cloud photoionization models. …”
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Polygenic prediction of human longevity on the supposition of pervasive pleiotropy by M. Reza Jabalameli, Jhih-Rong Lin, Quanwei Zhang, Zhen Wang, Joydeep Mitra, Nha Nguyen, Tina Gao, Mark Khusidman, Sanish Sathyan, Gil Atzmon, Sofiya Milman, Jan Vijg, Nir Barzilai, Zhengdong D. Zhang

“…Given the highly complex and non-linear interactions between the genetic determinants of longevity, we reasoned that a composite polygenic score would approximate a substantial portion of the variance in lifespan and developed the integrated longevity genetic scores (iLGSs) for distinguishing exceptional survival. …”
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Productivity loss due to menstruation-related symptoms: a nationwide cross-sectional survey among 32 748 women by Mark E Schoep, Eddy M M Adang, Jacques W M Maas, Bianca De Bie, Johanna W M Aarts, Theodoor E Nieboer

“…Objective To evaluate age-dependent productivity loss caused by menstruation-related symptoms, measured in absenteeism (time away from work or school) and presenteeism (productivity loss while present at work or school).Methods Design/setting: internet-based, cross-sectional survey conducted in the Netherlands from July to October 2017.Participants: 32 748 women aged 15–45 years, recruited through social media.Outcome measures: self-reported lost productivity in days, divided into absenteeism and presenteeism; impact of menstrual symptoms; reasons women give when calling in sick; and women’s preferences regarding the implications of menstruation-related symptoms for schools and workplaces.Results A total of 13.8% (n=4514) of all women reported absenteeism during their menstrual periods with 3.4% (n=1108) reporting absenteeism every or almost every menstrual cycle. …”
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Exploring the drivers of adolescent sexual and reproductive healthcare-seeking behavior in northwestern Botswana: a cross-sectional analysis by Mackenzie Lawson, Helen Apps, Peggie Ramaphane, Francis Barchi

“…At the multivariate level, younger respondents and those who had never been tested for HIV or had an STI had lower odds of forgone visits compared to their older peers and those who had been tested or had an STI. The most common reasons for forgoing visits reflected perceptions that nurses were unfriendly and did not believe adolescents should have sex. …”
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The sphingosine‐1‐phosphate signaling pathway (sphingosine‐1‐phosphate and its receptor, sphingosine kinase) and epilepsy by Lin Wang, Qingxia Kong, Xinyi Leng, Howan Leung, Yang Li

“…Here, we summarize and analyze the role of the S1P signaling pathway in epilepsy, provide a basis for finding potential therapeutic targets and/or epileptogenic biomarkers, analyze the reasons for these controversies, and put forward our opinions. …”
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Spatiotemporal Variations of PM2.5 and O3 Relationship during 2014–2021 in Eastern China by Yasong Li, Tijian Wang, Qin’geng Wang, Yawei Qu, Hao Wu, Min Xie, Mengmeng Li, Shu Li, Bingliang Zhuang

“…These findings serve as a valuable reference for formulating a reasonable collaborative control scheme for these two pollutants.…”
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Advances in the pilot point inverse method: Où En Sommes-Nous maintenant? by White, Jeremy, Lavenue, Marsh

“…While inversion research continues, only de Marsily’s PPM has achieved wide-spread adoption within the groundwater modeling community.The reasons for the popularity of the PPM are many but none more important than its adoption by John Doherty’s PEST inversion software in the early 2000s [Doherty, 2003]. …”
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Characterization of Vaginitis Among Women Complaining of Genital Tract Symptoms by Hemin Muheddin Kareem, Muhammed Saed Qadir, Safa Bakr Karim, Solaf Jawhar Ali

“…It is one of the most frequent reasons that women visit clinics. The objective of this study was to determine the importance of laboratory diagnosis methods in the treatment of the disease and to study the symptoms and risk factors associated with vaginitis among women with genital tract symptoms. …”
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Obesity prevalence among healthcare professionals in England: a cross-sectional study using the Health Survey for England by Richard G Kyle, Jane Wills, Catherine Mahoney, Louise Hoyle, Muireann Kelly, Iain M Atherton

“…Further research is required to better understand the reasons for high obesity prevalence among healthcare professionals in England to inform interventions to support individuals to achieve and maintain a healthy weight.…”
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Teaching accounting principles using augmented reality and artificial intelligence-generated IsiZulu language translations by Abejide Ade-Ibijola, Aneetha Sukhari, Solomon Sunday Oyelere

“…Earlier research found that the number of African chartered accountants in South Africa are inadequately represented and cited one of the reasons as being a language barrier. We propose that the translation of accounting concepts into indigenous African languages can improve the understanding of accounting principles which will allow for inclusive, equitable, and quality education for all. …”
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Rational design of novel phenol ether derivatives as non-covalent proteasome inhibitors through 3D-QSAR, molecular docking and ADMET prediction by Miao Yuan, Hanwen Ji, Fengxin Sun, Qiang Chen, Ping Cheng

“…In addition, the results of ADMET prediction indicated that the new designed compounds had reasonable PK parameters and drug-like properties. Conclusions: These statistical results can provide theoretical guidance for structural optimization, design, and synthesis of more effective non-covalent proteasome inhibitors in the future.…”
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Regional Medical Campuses in Canada by Aaron Johnston, Amanda Bell, Kristy Penner, Trushar Patel, Grace Perez

“…While the robust nature of the RMC model suggests that deployment into new settings is reasonable, the data also clearly shows areas that may be opportunities and challenges for each of these new, proposed, settings. …”
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"They gave us the right to choose." A qualitative study of preferences for differentiated service delivery location among recipients of antiretroviral therapy at Lighthouse Trust i... by Lisa Orii, Kate S Wilson, Jacqueline Huwa, Christine Kiruthu-Kamamia, Odala Sande, Agness Thawani, Astrid Berner-Rodoreda, Evelyn Viola, Hannock Tweya, Petros Tembo, Wapu Masambuka, Richard Anderson, Caryl Feldacker

“…In this qualitative study, we explore reasons why RoC enrolled in LT clinics and eligible for DSD chose clinic-based ART services or a Nurse-led Community-based ART Program (NCAP) that reaches clients in established community peer support groups. …”
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Automated Essay Scoring Menggunakan Semantic Textual Similarity Berbasis Transformer Untuk Penilaian Ujian Esai by Kharisma Ayu Pradani, Lya Hulliyyatus Suadaa

“…However, assessing this type of answer takes a lot of time and effort and often results in inconsistencies. One of the reasons is the different ways between people while doing the assessment. …”
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Factors Affecting Male Involvement in Family Planning at Kazo Health Center IV in Kazo Town Council Kazo District. by Ndyaguma, Laban

“…Among the views pointed out by the respondent's on men's participation in family planning as highlighted in the study also agreed with the related literature like culture factors, religious beliefs, social economic factors and psychological factors, Also suggested some other reasons like Ignorance lack of time false myth and fear of family planning side effects as mentioned by the majority of respondents as discussed during a focus group discussion where they mentioned that condoms cause cancer. …”
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Uptake and hesitancy of the second booster dose of COVID-19 vaccine among the general population in China after the surge period of the COVID-19 pandemic: a large-scale national st... by Xin Liu, You Xin, Ling Zhang, Yijin Wu, Shu Jing, Zhenwei Dai, Tianrui Ren, Xiaoyang Liu, Jiaqi Fu, Xu Chen, Weijun Xiao, Hao Wang, Yiman Huang, Wenjun Wang, Xiaofen Gu, Li Ma, Shaokai Zhang, Yanqin Yu, Li Li, Tianzuo Gao, Tianyou Zhao, Yimin Qu, Xinyan Liu, Xiaoyou Su, Youlin Qiao

“…To improve coverage of the second booster dose, it is crucial to investigate the prevalence of vaccine hesitancy among the general population during this period and explore the reasons for this phenomenon. Methods A cross-sectional survey was conducted between January 5 to February 9, 2023. …”
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CytoSorb hemoadsorption of apixaban during cardio-pulmonary bypass for heart transplantation by Anouk Frering, MD, Antoine Abi Lutfallah, MD, Aude Carillion, MD, PhD, Daniel Wendt, MD, Pascal Leprince, MD, PhD, Adrien Bougle, MD, PhD, Guillaume Lebreton, MD, PhD

“…Patients on the transplant waiting list often have multiple reasons for being anticoagulated. Intraoperative removal of apixaban using CytoSorb seems to be an interesting solution for patients on DOACs requiring an emergency CPB intervention. …”
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