A Randomized Controlled Trial Comparing Sequential with Triple Therapy for Helicobacter pylori in an Aboriginal Community in the Canadian North by Amy L Morse, Karen J Goodman, Rachel Munday, Hsiu-Ju Chang, John Morse, Monika Keelan, Janis Geary, Sander Veldhuyzen van Zanten, CAN Help Working Group

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Mindfulness influences the psycho-social dimension of chronic pain: A randomized controlled clinical trial in Indian context by Anirban Pal, Purnava Mukhopadhyay, Rajasree Biswas, Dipasri Bhattacharya

“…Materials and Methods: In this two-site, parallel group, clinical trial, 170 patients attending pain outdoors of two government hospitals in West Bengal, India, were randomized to attend five weekly in-person mindfulness sessions (cases) or usual care sessions (controls) within the hospital premises. …”
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Random-Parameter Multivariate Negative Binomial Regression for Modeling Impacts of Contributing Factors on the Crash Frequency by Crash Types by Chenzhu Wang, Fei Chen, Jianchuan Cheng, Wu Bo, Ping Zhang, Mingyu Hou, Feng Xiao

“…Independent negative binomial and Poisson models are considered as the base approaches to modeling in this study. However, random-parameter models reduce unobserved heterogeneity and obtain higher dimensions. …”
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Analgesic Effects of Preincision Ketamine on Postspinal Caesarean Delivery in Uganda’s Tertiary Hospital: A Randomized Clinical Trial by Richard Mwase, Tonny Stone Luggya, John Mark Kasumba, Humphrey Wanzira, Andrew Kintu, Joesph V. B. Tindimwebwa, Daniel Obua

“…We did an RCT among consenting parturients that were randomized to receive either intravenous ketamine (0.25 mg/kg) or placebo after spinal anesthetic. …”
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Randomized Clinical Trial of a Self-Adhering Flowable Composite for Class I Restorations: 2-Year Results by J. Sabbagh, S. Dagher, N. El Osta, P. Souhaid

“…Thirty-four pairs of restorations were randomly placed by the same operator. Fifteen patients were treated under rubber dam and nineteen using cotton rolls isolation and saliva ejector. …”
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Motivational interviewing to improve self‐care in heart failure patients (MOTIVATE‐HF): a randomized controlled trial by Ercole Vellone, Paola Rebora, Davide Ausili, Valentina Zeffiro, Gianluca Pucciarelli, Gabriele Caggianelli, Stefano Masci, Rosaria Alvaro, Barbara Riegel

“…Methods and results Parallel randomized controlled trial (1:1:1). A sample of 510 patients (median 74 years, 58% male) and caregivers (median 55 years, 75% female) was randomized to Arm 1 (MI only for patients), Arm 2 (MI for patients and caregivers), or Arm 3 (usual care). …”
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Rifaximin treatment in patients with severe alcoholic hepatitis: A multicenter, randomized controlled, open-label, pilot trial by Do Seon Song, Jin Mo Yang, Young Kul Jung, Hyung Joon Yim, Hee Yeon Kim, Chang Wook Kim, Soon Sun Kim, Jae Youn Cheong, Hae Lim Lee, Sung Won Lee, Jeong-Ju Yoo, Sang Gyune Kim, Young Seok Kim

“…Material and Methods: In this randomized controlled open-label trial, patients with SAH (Maddrey's discriminant function≥32) were randomized to the rifaximin or control group. …”
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Improvement of Fatigue in Patients with Ankylosing Spondylitis Receiving Tofacitinib: Analyses of a Phase 3 Randomized Controlled Trial by Laure Gossec, Jessica A. Walsh, Raj Sengupta, Andrew G. Bushmakin, Joseph C. Cappelleri, Arne Yndestad, Oluwaseyi Dina, David Cella

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Randomized clinical trial of a digital integrative medicine intervention among patients undergoing active cancer treatment by Jun J. Mao, Karolina Bryl, Erin F. Gillespie, Angela Green, Tony K. W. Hung, Raymond Baser, Katherine Panageas, Michael A. Postow, Bobby Daly

“…Abstract Exercise and mindfulness-based interventions have growing evidence for managing fatigue and comorbid symptoms; however, packaging them in a cohesive digital way for patients undergoing cancer treatment has not been evaluated. We conducted a randomized controlled trial to assess the impact of a 12 week digital integrative medicine program, Integrative Medicine at Home (IM@Home), versus enhanced usual care on fatigue severity (primary outcome), comorbid symptoms and acute healthcare utilization (secondary outcomes), in 200 patients with solid tumors experiencing fatigue during treatment. …”
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Effectiveness of Anti-Gravity Treadmill Exercise After Total Knee Arthroplasty: Protocol for a Randomized Controlled Trial by Elina Jääskeläinen, Mikko Manninen, Heikki Hurri, Mikko Rantasalo, Yun Zhou, Hannu Kautiainen, Leena Ristolainen

“…MethodsThis randomized controlled trial study divided the patients into two groups: the intervention group and the control group. …”
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Effectiveness of Scapular Stabilization Versus Non-Stabilization Stretching on Shoulder Range of Motion, a Randomized Clinical Trial by Alan J Howell, Andrew Burchett, Nicholas Heebner, Cody Walker, Alec Baunach, Asia Seidt, Tim L Uhl

“…. # Study Design Randomized Clinical Trial # Methods Sixteen patients with sub-acromial pain associated with tendinopathy and associated pathologies presenting to physical therapy were randomized into two groups (stabilized or non-stabilized scapular stretching). …”
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A Low Dose of Naloxone Added to Ropivacaine Prolongs Femoral Nerve Blockade: A Randomized Clinical Trial by Seung Cheol Lee, Jeong Ho Kim, So Ron Choi, Sang Yoong Park

“…This study evaluated whether a low dose of naloxone administered with local anesthetics prolongs the duration of FNB. A prospective, randomized double-blind controlled study was conducted with 74 patients undergoing unilateral TKA. …”
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Effects of Intraoperative Dexamethasone and Ondansetron on Postoperative Nausea and Vomiting in Microvascular Decompression Surgery: A Randomized Controlled Study by Cattleya Thongrong, Patitha Chullabodhi, Pornthep Kasemsiri, Amnat Kitkhuandee, Narin Plailaharn, Lumyai Sabangban, Thirada Jimarsa

“…A prospective, double-blinded, randomized control trial was conducted with 54 patients who underwent MVD. …”
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Damage Simulation of a Random Aggregate Model Induced by Microwave under Different Discontinuous Ratios and Exposure Times by Yang Tang, Guobin Xu, Chunlai Qu, Liying Sun, Yu Duan

“…A random aggregate algorithmic method and a numerical model for two-phase materials (composed of quartz and plagioclase) with different discontinuous ratios and irradiation times were studied based on the discrete element method using two-dimensional particle flow code (PFC2D). …”
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Oral dydrogesterone versus oral micronized progesterone in threatened miscarriage: protocol paper for a randomized controlled trial by Alka Kriplani, Gouri Shankar Kamilya, T Ramani Devi, Ashima Taneja, Amol Pawar, Gayathri Karthik Nagesh, Tapan Pattanaik, Tanusree Gupta, Mahima Jain, Monjori Mitra

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Effect of Virtual Reality Therapy with Brain Gym Exercises for Sleep-deprived Individuals: A Randomized Clinical Trial by Marissa De Souza Eremita, Jeba Chitra

“…Materials and Methods: A randomized clinical trial was performed by screening 51 samples, from which 32 individuals were recruited, using purposive sampling, based on the Pittsburgh Sleep Quality Index (PSQI) which was used as the inclusion criteria. …”
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Controlled-Release Oxycodone and Naloxone in the Treatment of Chronic Low Back Pain: A Placebo-Controlled, Randomized Study by C Cloutier, J Taliano, W O’Mahony, M Csanadi, G Cohen, I Sutton, D Sinclair, M Awde, S Henein, L Robinson, J Eisenhoffer, PS Piraino, Z Harsanyi, KJ Michalko

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Comprehensive Sepsis Risk Prediction in Leukemia Using a Random Forest Model and Restricted Cubic Spline Analysis by Kou Y, Tian Y, Ha Y, Wang S, Sun X, Lv S, Luo B, Yang Y, Qin L

“…Furthermore, we examined the interactions among predictors to better understand their potential interrelationships.Results: The random forest (RF) model outperformed all others, achieving an AUC of 0.765 in the training cohort and 0.700 in the validation cohort. …”
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Causal Relationship Between Emotional Disorders and Thyroid Disorders: A Bidirectional Two‐Sample Mendelian Randomization Study by Jiaying Fan, Kai Zhou, Cuiwen Yu

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Two-machine flowshop scheduling problem to minimize makespan or total completion time with random and bounded setup times by Ali Allahverdi, Tariq Aldowaisan, Yuri N. Sotskov

“…Setup times are relaxed to be random variables rather than deterministic as commonly used in the OR literature. …”
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