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Comparative safety and effectiveness of cryoballoon versus radiofrequency ablation for atrial fibrillation: a systematic review and meta-analysis
Published 2025-02-01“…Methods This study compared the safety and effectiveness of CBA and RFCA for the treatment of AF using a thorough review of randomized controlled trials up until June 1, 2023. Results The results revealed that CBA and RFCA had similar effectiveness and safety profiles in achieving freedom from AF (RR: 1.00; 95% CI: 0.93 to 1.07, p = 0.99) and paroxysmal atrial fibrillation (PAF) (RR: 0.99; 95% CI: 0.89 to 1.10, p = 0.79). …”
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222
Comparison of efficacy and safety of thrombus prevention strategies after abdominal and pelvic cancer surgery: Bayesian network based meta-analysis
Published 2025-02-01“…However, there is insufficient evidence supporting the choice of anticoagulation strategies.MethodsWe searched PubMed, The Cochrane Library, Embase, and Web of Science for randomized controlled trials from inception to January 2024. …”
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223
The effectiveness of dyadic interventions for health outcomes of prostate cancer patients and informal caregivers: a systematic review and meta-analysis
Published 2025-02-01“…However, given features such as research quality and sample size, further randomized controlled trials with excellent study designs are needed in the future to evaluate and validate the efficacy of dyadic care treatments for patients with prostate cancer. …”
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224
Exploring the association between statins use or HMG-CoA reductase inhibition and migraine: a systematic review and meta-analysis
Published 2025-02-01“…Meta-analysis of randomized controlled trials (RCTs) showed that statins significantly reduced monthly migraine frequency (MD= -3.16, 95%CI= [-5.79, -0.53]; p = 0.02, I2 = 79%; P = 0.03). …”
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225
“Inclisiran: Early LDL-C target achievement in a real-life population”
Published 2025-03-01“…Inclisiran, a small interfering RNA, has been observed to effectively and sustainably reduce LDL-C in large randomized controlled trials (RCTs); however, real-world data on its short-term efficacy and use are limited. …”
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226
Proximal Hamstring Tendinopathy: A Systematic Review of Interventions
Published 2021-04-01“…Reporting quality was assessed using the Cochrane Risk of Bias Tool (Randomized Controlled Trials \[RCT\]) and the Joanna Briggs Institute Checklist (Case Series). …”
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227
Comparative efficacy of acupuncture therapies in premature ovarian failure: A systematic review and network meta-analysis
Published 2025-05-01“…Design: We systematically searched six databases from their inception to April 2024 for randomized controlled trials (RCTs) of acupuncture therapies for POF. …”
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228
Laparoscopic suture repair for perforated peptic ulcer disease: a meta-review and trial sequential analysis
Published 2025-02-01“…Meta-epidemiology, as a form of evidence synthesis, allows for the pooling of data and assessment of the diversity present in multiple and overlapping SRs.Aim of the researchThis study aimed to summarize evidence from systematic reviews of randomized controlled trials and reanalyze outcome data on laparoscopic suture repair of perforated peptic ulcers using trial sequential analysis (TSA).Materials and methodsThe Cochrane Library, PubMed, Embase, CINAHL, eLibrary, and ClinicalTrials.gov were searched before 1 June 2024. …”
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229
Effects of lower limb strengthening training on lower limb biomechanical characteristics and knee pain in patients with patellofemoral pain: a systematic review and meta-analysis
Published 2025-02-01“…The selected studies comprised nine randomized controlled trials (RCTs), one comparative controlled trial (CCTs) and two cohort studies (CSs), with a total of 1,066 patients. …”
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230
Rapid Verbal Persuasion to increase influenza vaccine uptake: protocol for a randomized hybrid type 2 effectiveness -implementation trial
Published 2025-02-01“…Method This study will be conducted as a two-tiered cluster of randomized controlled trials over three months. Initially, 32 vaccination clinics will be randomly allocated to one of two study arms: (a) implementation of RVP or (b) no implementation. …”
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231
Donafenib combined with sintilimab for advanced hepatocellular carcinoma: a single arm phase II trial
Published 2025-02-01“…The preliminary findings need to be further evaluated in phase III randomized controlled trials. Trial registration ClinicalTrials.gov (identifier: NCT05162352; date of registration: December 4, 2021).…”
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232
The effects of acute and chronic exercise on immune markers of TH1/TH2 cells in older adults: a systematic review
Published 2025-02-01“…This review investigates the impact of acute and chronic exercise on immune markers of Th1 and Th2 cells in the older adults.MethodsThis study was conducted as a systematic review, following PRISMA guidelines, databases including PubMed, Web of Science, Embase, Science Direct, and Scopus were searched until March 2024, identifying randomized controlled trials and prospective observational studies that examined the effects of acute and chronic exercise on intracellular and surface markers, cytokines, and immunoglobulins in older adults. …”
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233
Comparing the Effects of Integrative Neuromuscular Training and Traditional Physical Fitness Training on Physical Performance Outcomes in Young Athletes: A Systematic Review and Me...
Published 2025-02-01“…Results Seventeen randomized controlled trials with 649 young athletes were included in the systematic review. …”
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234
Ivermectin as a promising therapeutic option for onchocerciasis‐associated epilepsy
Published 2025-02-01“…However, there is a need for more randomized controlled trials specifically evaluating ivermectin's impact on seizures in O. volvulus‐infected epileptics on ASMs. …”
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235
Efficacy of electroacupuncture for insomnia in cancer patients: a systematic review and meta-analysis
Published 2025-02-01“…Data were analyzed using RevMan 5.4 and Stata 15.0 software.ResultsEight randomized controlled trials (RCTs) involving 550 patients (305 in the experimental group and 245 in the control group) were included. …”
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236
The efficacy of sodium-glucose transporter 2 inhibitors in patients with nonalcoholic fatty liver disease: A systematic review and meta-analysis
Published 2025-03-01“…We systematically searched major electronic databases (PubMed, Cochrane Library, Web of Science, Embase) from inception until 11/2023, identifying randomized controlled trials (RCTs) of SGLT-2 inhibitors treatment for patients with NAFLD. …”
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237
Acupuncture for somatosensory deficits after stroke: a systematic review and meta-analysis
Published 2025-02-01“…ObjectiveThis meta-analysis aimed to evaluate the randomized controlled trials (RCTs) of acupuncture for somatosensory deficits after stroke to provide the current best evidence for clinical practice.MethodsA systematic search was performed for eligible articles on the acupuncture for somatosensory deficits after stroke based on 14 databases. …”
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238
Clinical outcome analysis for surgical fixation versus conservative treatment on rib fractures: a systematic evaluation and meta-analysis
Published 2025-02-01“…Results A total of 47 studies involving 1,078,795 patients were included, consisting of three randomized controlled trials and 44 case–control studies. The results demonstrated that patients who underwent SSRF experienced better outcomes than those receiving conservative treatment in terms of all-cause mortality. …”
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239
Efficacy and safety of sequential therapy for primary osteoporosis with bone formation promoters followed by bone resorption inhibitors: a meta-analysis
Published 2025-02-01“…Methods PubMed, the Cochrane Library, Web of Science, and Embase databases were retrieved to identify pertinent studies. Randomized controlled trials (RCTs) on the sequential therapy of primary osteoporosis with bone formation promoters followed by bone resorption inhibitors were included. …”
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240
A systematic review and meta-analysis of the impact of transcranial direct current stimulation on cognitive function in older adults with cognitive impairments: the influence of do...
Published 2025-02-01“…This study further explores the impact of tDCS and its dosage parameters on cognitive enhancement in older people with cognitive impairments. Methods Randomized controlled trials (RCTs) published through November 2023 were retrieved from databases including PubMed, Scopus, EMBASE, EBSCO, and the Cochrane Library. …”
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